摘要
给卒中型自发性高血压大鼠 (SHRsp)预先口服艾地苯醌 ,可延缓用手术方式结扎大鼠双侧颈总动脉造成的急性脑缺血的痉挛发作出现时间及延长 36 h内存活时间。脑卒中发生后 ,用艾地苯醌治疗可明显减轻 SH Rsp神经系统的损害 ,增加体重 ,改善存活期。
The results showed that idebenone can delay the time of spasm onset and prolong the time of survival from acute cerebral ischemia in stroke-prone spontaneously hypertensive rats(SHRsp).It can also reduce damages to the nervous system,increase body weight and improve the survival from stroke of SHRsp.
