摘要
目的:观察146名TIA患者的情感障碍及认知功能,探索TIA患者卒中后抑郁对认知功能障碍的影响。方法:采用汉密尔顿抑郁量表(HAMD)和中文版简易智能量表(MMSE)进行抑郁及认知障碍评定。结果:卒中后抑郁和卒中后认知功能障碍的发生率分别为20.55％和35.62％。抑郁组与非抑郁组患者的MMSE评分有非常显著的差异(P=0.001),两组患者的认知功能异常率也有显著差异(P=0.002)MMSE得分和认知功能异常率与HAMd评分密切相关(P值分别为0.002,0.030)。结论:TIA患者卒中后抑郁与认知功能障碍有着密切关系。
Objective: To study the effects of post - stroke depression (PSD) on cognitive functions in 146 patients with TIA. Methods: Hamilton depression rating scale for depression (HAMD) and mini mental state examination (MMSE) were used to assess depression and cognitive function. Results: Incidence of PSD and cognitive impairment was 20.55% , 35.62%, respectively. The difference of the score on the MMSE and the incidence of cognitive impairment between PSD group and non-PSD group were statistically significant (P = 0.001, 0.002) . The scores on MMSE, as well as incidence of cognitive impairment, were associated with scale of HAMD(P = 0.002, 0.030). Conclusion: Our findings suggest a definitive association of PSD with cognitive impairment in patients with TIA.
出处
《现代医药卫生》
2003年第5期522-523,共2页
Journal of Modern Medicine & Health
