2Klokkers-Bethke K, Fischer W. Development of multiple unit drug delivery system for positioned release in the gastrointestinal tract [J]. J Controlled Release,1991, 15(1):105-112.
3Davis SS, Hardy JG, Fara JW. Transit of pharmaceutical dosage forms through the small intestine [J].Gut, 1986, 27(8):886-892.
4Ishibashi T, Pitcaim GR, Yoshino H, et al. Scintigraphic evaluation of a new vapsule-type colon specific drug delivery system in health volunteers[J]. J Pharm Sci, 1998, 87(5):531-534.
5Evans DF, Pye G, Bramley R, et al. Measurments of gastrointestinal pH profiles in normal ambulant human subjects[J]. Gut, 1988, 29(8):1035-1041.
6Lemmer B. Implications of chronopharmacokinetics for drug delivery:antiasthmaties, H2-blockers and cardiovascular active drugs [J]. Adv Drug Deliv Rev,1991, 6(1):83-100.
8Makoto Otsuka,Yoshihisa Matsuda. Controlled Drug Release of Highly Water-Soluble Pentoxifylline from Time-Limit Disintegration-Type Wax Matrix Tablets[J] 1994,Pharmaceutical Research(3):351~352
9Ian R. Wilding,Stanley S. Davis,Massoud Bakhshaee,Howard N. E. Stevens,Robert A. Sparrow,John Brennan. Gastrointestinal Transit and Systemic Absorption of Captopril from a Pulsed-Release Formulation[J] 1992,Pharmaceutical Research(5):654~657