摘要
探讨低血钙症与机体体液免疫功能间的关系。对74例低血钙患儿和30名血钙正常的小儿进行了血清免疫球蛋白及补体C_3水平的测定。结果低血钙症患儿血清IgG明显降低(P<0.05),补体C_3明显升高(P<0.01),而IgA、IgM变化不显著(P>0.05)。低钙的严重程度、性别、年龄等因素对其免疫状态影响不大(P>0.05),低血钙纠正后,患儿的免疫功能有明显改善。提示低血钙症可导致机体体液免疫功能紊乱。
For study the relationship of hypocalcemia and humoral immunity function(HIF) the levels of serum immunoglobulin (Ig) and additament (C3) were determined in 74 infants with hypocalcemia (group A) and in 30 normocalcemic children (group B). The results showed: IgG was lower in group A than in group B (P<0.05), C3 was higher in group A than in group B (P<0.01), the levels of IgA, IgM were similar in both groups (P>0.05). But the severity of hypocalcemia, sex, and age had no influence on HIF (P>0.05). After the level of serum calcium had been raised to normal by treatment, there was notable improvement on HIF of the group A infants. It was suggested that hypocalcemia resulted in disturbance of HIF.
出处
《天津医药》
CAS
1993年第11期670-672,共3页
Tianjin Medical Journal
关键词
低钙血症
免疫功能紊乱
T细胞亚群
hypocalcemia humoral immunity function T cell subpopulation