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孕妇血清HBV-DNA含量对预测胎儿宫内感染的临床价值 被引量:1

Clinical value of serum HBV-DNA content for measuring intrauterine fetal infection
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摘要 目的:探讨孕妇血清HBV-DNA含量对预测胎儿宫内感染的临床价值。方法:应用聚合酶链反应(PCR)法检 测103例乙型肝炎表面抗原(HBsAg)阳性孕妇的血清HBV-DNA含量,并对相关因素进行分析。结果:103例HBsAg阳性孕妇 的HBV-DNA检出阳性率为56%,胎儿宫内感染率为12.6%,且胎儿宫内感染率随血清HBV-DNA含量的增加而升高, HBV-DNA含量与胎儿宫内感染率呈正相关(r=0.572,P<0.01)。结论:孕妇血清HBV-DNA含量可间接预测胎儿宫内感染 的发生率。 Objective: To study the clinical value of serum HBV-DNA content for measuring intrauterine fetal infection. Methods: Polymerase chain reaction (PCR) was used to measure serum HBV-DNA content in 103 HBsAg positive pregnant woment, and the results are analyzed. Results: The positive rate of HBV-DNA was 56%, intrauterine fetal infection rate was 12. 6% , and the rate of fetal intrauterine infection was increasing with the increase of serum HBV-DNA content. Conclusion: Fetal intrauterine infection was relative with serum HBV-DNA content of pregnant women.
出处 《中国妇幼保健》 CAS 2004年第12期52-53,共2页 Maternal and Child Health Care of China
关键词 乙型肝炎病毒 宫内感染 胎儿 DNA Hepatitis B virus Intrauterine infection Fetal DNA
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  • 1刘志华,徐德忠,闫永平,门可,张景霞,徐剑秋,蒋美玲.孕妇血清中乙型肝炎病毒DNA含量与胎儿宫内感染的关系[J].中华妇产科杂志,1999,34(3):133-134. 被引量:68
  • 2钱宇平主编.流行病学[M].北京:人民卫生出版社,1998.38.
  • 3Memahon BJ, Bulow L, Harpster A et al.Sereening for hepatoeellular carcinoma in Alaska natives infected with chronic hepatitis B: a 16-year population-based study. Hepatology, 2000, 32 (4 pt 1): 842-846.
  • 4Burk RD, Huang LY, Ho GY et al. Outcome of perinatal hepatitis B virus exposure is dependent on maternal virus load. J Infect Dis, 1994, 170 (6): 1418-1423.
  • 5Lin HH, Lee TY, Chen DS et al, Transplaeental leakage of HBeAg -positive maternal blood as the most likely route in causing intrauterine infection with hepatitis B virus, J Pediatr, 1987, 111(6 Pt 1): 877-881.
  • 6Sumazaki R, Motz M, Wolf H et al. Detection of hepatitis B virus in serum using amplification of viral DNA by means of polymerse chain reaction. J Med Virol, 1989, 27:304-308.

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