摘要
目的探讨伽玛刀治疗对前庭神经鞘瘤的疗效及对面听神经功能的影响。方法从1994年12月至2002年12月治疗并随访226例单侧前庭神经鞘瘤患者,平均临床随访期25.8个月(6～101个月),平均MRI随访期21.8个月(6～93个月)。结果226个瘤灶中70个体积缩小(31.0%),145个体积改变不明显(64.1%),11个体积扩大(4.9%),肿瘤控制率95.1%。听力下降率20.4%,永久面瘫率0%,一过性面瘫率6.2%,三叉神经症状加重21.2%。结论伽玛刀治疗对较小体积的前庭神经鞘瘤有良好的控制疗效,对面听神经功能有明显的保留作用。
Objective The aim of this article was to evaluate the effect of the gamma radiosurgery(GRS) for vestibular schwannoma(VS) . Methods 226 patients with vestibular schwannomas underwent GRS and were reviewed in our Beijing Neurosurgical Institute(BNI) between December 1994 and December 2002.The mean clinical follow-up period and radiological follow-up period was 25.8months(6～101months) and 21.8months(6～93months) respectively. Results With radiological follow-up 70 tumors(31.0%) regressed,145 tumors(64.1%) remained unchanged,11 tumors(4.9%) grew,and the overall tumor control rate was 95.1%.The rate of hearing deterioration was 20.4%,the rate of permanent facial paralysis was 0%,the rate of transient facial paralysis was 6.2%,and the incidences of trigeminal neuropathies were 21.2%. Conclusion GRS is effective for small VS and provide an visible protection for cranial nerve.
出处
《中国医刊》
CAS
2004年第12期22-24,共3页
Chinese Journal of Medicine
