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新生儿疾病筛查的安全性和有效性评价 被引量:3

Safety and effectiveness assessment of neonatal disease screening
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摘要 目的 评价影响新生儿疾病筛查安全性与有效性的因素 ,为构建新生儿疾病筛查管理机制提供依据。方法 运用循证医学的理念 ,采用文献归纳方法对新生儿疾病筛查的安全性和有效性进行评价。结果 新生儿疾病筛查技术具有很高的安全性 ,但影响有效性的环节和因素很多 ,文献中报道的采血时间、检测方法、切值水平、效果评价指标等方面均存在一定差异 ,有效性令人忧虑。结论 重视对筛查技术安全性的认识和评价 ; Objective To assess the safety and effectiveness of neonatal disease screening so as to provide basis for the establishment of a mechanism for managing neonatal disease screening. Methods Using the ideas of evidence-based medicine, a safety and effectiveness assessment of neonatal disease screening was made by means of literature induction. Results The techniques used in neonatal disease screening were highly safe, but their effectiveness was affected by a variety of links and factors. The differences reported in literature in such aspects as blood-collecting time, testing methods, cut-off values, and indexes for outcome evaluation might mean negative impact on the effectiveness. Conclusion More attention ought to be attached to the understanding and assessment of the safety of screening techniques and more efforts need to be made in conducting systematic studies into the effectiveness of screening techniques.
出处 《中华医院管理杂志》 2004年第12期716-719,共4页 Chinese Journal of Hospital Administration
基金 卫生部妇幼卫生与社区卫生司资助项目 ( 2 0 0 3 )
关键词 新生儿疾病筛查 安全性 循证医学 采血时间 效果评价 影响 因素 有效性 文献 归纳方法 Disease, Neonate Disease screening Safety Effectiveness
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参考文献5

  • 1American Academy of Pediatrics. Serving the family from birth to the medical home. Pediatrics, 2000,106:389-421.
  • 2WHO. Guidelines on the prevention and control of Phenylketonuria. 1990.
  • 3WHO. Guidelines on the prevention and control of Congenital hypothyroidism. 1991.
  • 4White KR, Behrens TR. The Rhode Island Hearing Assessment Project: implications for universal newborn hearing screening. Semin Hear,1993,14:1-122.
  • 5National Institute of Health and Human Services: NIH Consensus Statement: early identification of hearing impairment in infants and young children. NIH, 1993,11:1-24.

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