摘要
阿斯匹林和双嘧哌胺醇对ADP诱导的血小板聚集均有抑制作用,不同剂量的两药复方制剂复方潘生丁缓释片对体外血小板聚集抑制率分别为49.4%、67.9%,半体内血小板聚集抑制率分别为24.0%、47.1%,表明其抗血小板聚集作用比两药单用明显增强。
The effects of aspirin,dipyridamole and Sustained Release Tablet(SRT of DPD Co.)on platelet aggregation were studied.The inhibitory rates of platelet aggregation of SRT of DPD Co.on platelet aggregation induced by ADP in different doses were 49.4%, 67.9%(in vitro)and 24.0%,47.1%(in vivo)respectively.The results show that SRT of DPD Co.is a potent inhibitor of platelet aggregation both in vitro and in vivo.Its action sur- passes that of aspirin and dipyridamole used separately.
关键词
阿斯匹林
双嘧哌胺醇
血小板聚集
scetylsalicylic acid
dipyridamole
platelet aggregation
comparative study
