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重症病毒性肝炎预后探讨

APPROACH ON PROGNOSIS OF SEVERE VIRAL HEPATITIS
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摘要 94例重症病毒性肝炎病人,按全国肝炎诊断标准分别诊断为急性重症、亚急性重症及慢性重症肝炎,其中54例死亡,死亡率为57.4%。其预后与残存肝细胞数量,并发症,胆红素浓度,凝血酶原活动度,胆碱酯酶活力,血清总胆固醇等有关。血清胆红素>34(?)mmol/L,胆碱酯酶活力<3000U/L,凝血酶原活动度<15%,胆固醇<1.8mmol/L。肝(?)迷Ⅳ级均为预后不佳的指征。感染、脑水肿、消化道出血、肝肾综合征则是该病致死性并发症。 Ninty four patients were diagnosed as having fulminant hepatitis,subacute severe hepatitis and chronic severe hepatitis,respectively,according to the diagnostic criteria for viral hepatitis, The mortality was 57.4%(54/94),It is suggested that the quantity of surviving hepatocytes, complications,concentration of total serum bilirubin(SB),prothrombin activity(PTA), cholinesterase activity(CHA)and serum cholesterol(CHOL)are related with the prognosis.SB> 342μmol/L,PTA<15%,CHOL<1.8mmol/L indicate a poor prognosis.Infection,cerebral ede- ma,gastro-intestinal bleeding,hepatic coma IV and hepato-renal syndrome are grave complica- tions that resulte in death.
出处 《南京铁道医学院学报》 1993年第4期214-217,共4页 Journal of Nanjing Railway Medical College
关键词 病毒性肝炎 预后 重症肝炎 Severe viral hepatitis Complications Prognosis
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