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先心病体外循环术后血气指征在呼吸管理中应用的初步探讨 被引量:1

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摘要 目的 探讨小儿先心病体外循环心内直视手术后撤离呼吸机、拔除气管导管(撤机、拔管)血气指征和早期预测成败的指标。方法 非选择性调查PICU撤机、拔管病例血气分析与转归,按撤机、拔管转归和PaO2/FiO2(mmHg)分组,比较各组PaO2、PaCO2、PaO2/FiOa及成败比率。结果 3个月调查了30例次撤机、拔管前和1 h后血气分析结果,其中21例次成功,9倒次失败。成功组:撤机、拔管前后各血气值比较,均P>0.05;失败组:撤机、拔管前后比较,PaCO2P>0.05,而PaO2、PaO2/FiO2均P<0.05;撤机前PaCO2>45 mmHg与<45 mmHg组成功率比较,P>0.05;拔管后1 h PaCO2>45 mmHg与<45 mmHg组成功率比较,P<0.05。PaO2/FiO2不同水平拔管成功率比较:撤机前>200 mmHg与<200mmHg比较,P<0.01,<200 mmHg者无1例成功;拔管后1 h各组成功率比较,P<0.01,<250 mmHg者无1例成功;拔管后PaO2/FiO2升高与降低者比较,P<0.01,升高组成功率100%(11:11)。结论 撤机、拔管血气指征:PaO2、PaCO2、pH值正常,PaO2/FiO2>200 mmHg。拔管后1 h PaO2/FiO2比前升高、PaCO2<45 mmHg、PaO2/FiO2>250 mmng、PaO2(吸氧下)无下降者预示撤机、拔管将成功,PaCO2>45 mmHg、PaO2/FiO2<250 mmHg、PaO2(吸氧下)显著性下降者,需再次气管插管呼吸机治疗。
出处 《南华大学学报(医学版)》 2004年第4期507-509,共3页 Journal of Nanhua University(Medical Edition)
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