期刊文献+

热性惊厥患儿神经元特异性烯醇化酶、一氧化氮、一氧化氮合酶的变化 被引量:6

Changes of neuron-specific enolase, nitric oxide, nitric oxide synthase in children with febrile convulsion
暂未订购
导出
摘要 目的探讨热性惊厥(FC)患儿血清和脑脊液(CSF)神经元特异性烯醇化酶(NSE)、一氧化氮(NO)和一氧化氮合酶(NOS)的含量及其与FC发病机制、脑损伤的关系。方法分别采用电化学发光法、硝酸还原酶法、酶测定法测定FC患儿血清和CSF中NSE、NO、NOS的含量。 结果 FC组血清和CSF中NSE水平均明显高于对照组(P均<0.05);严重组FC患儿血清和CSF中NSE水平明显高于普通组(P<0.05)。FC组CSF中NO水平、NOS活性均明显低于对照组(P均<0.05) 结论 FC发作可引起血清和CSF中NSE水平升高,可导致神经元损伤。
出处 《实用儿科临床杂志》 CAS CSCD 北大核心 2004年第12期1072-1074,共3页 Journal of Applied Clinical Pediatrics
  • 相关文献

参考文献8

二级参考文献20

  • 1夏吉荣,伯孝华,黄天禄,马志如.脑脊液保存条件对神经元特异性烯醇化酶测定结果的影响分析[J].陕西医学检验,1996,11(4):34-35. 被引量:6
  • 2[1]Dube C, Chen K, Eghbal-Ahmadi M,et al. Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long term[J]. Ann Neurol,2000; 47: 336~344
  • 3[2]Holmes GL. Do seizures cause brain damage[J]?Epilepsia,1991; 32(suppl 5): S14~28
  • 4[3]Freeman JM. A clinical approach to the child with seizures and epilepsy[J]. Epilepsia,1987; 28(suppl 1): S103~109
  • 5[4]Jiang W, Duong TM,De Lanerolle NC. Neuropathology of hyperthermic seizures in the rat[J]. Epilepsia,1999; 40(1):5~19
  • 6[5]Morris R. Developments of a water-maze procedure for studying spatial learning in the rat[J].J Neurosci Methods,1984;11(1):47~60
  • 7[6]Holmes GL, Gairsa JL, Chevassus-Au-Louis N,et al. Consequences of neonatal seizures in the rat: morphological and behavioral effects[J]. Ann Neurol,1998; 44(5): 845~857
  • 8[7]Cronin J,Dudek FE. Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats[J]. Brain Res,1988; 474(1): 181~184
  • 9[8]Cronin J, Obenaus A, Houser CR,et al. Electrophysiology of dentate granule cells after kainate-induced synaptic reorganization of the mossy fiber[J]. Brain Res,1992; 573(2): 305~310
  • 10[9]Lipp HP, Schwegler H, Driscoll P. Postnatal modification of hippocampal circuitry alters avoidance learning in adult rats[J]. Science,1984; 225(4657): 80~82

共引文献49

同被引文献80

引证文献6

二级引证文献77

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部