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同种异体骨融合技术在脊柱侧凸手术治疗中的应用 被引量:7

Freezedried allograft of posterior spinal fusion in patients with scoliosis
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摘要 目的 观察同种异体骨在治疗脊柱侧凸时的有效性和安全性。方法 对 5 4例脊柱侧凸患者采用同种异体骨植骨融合 ,随访 4 1例 ,平均随访 16个月。观察同种异体骨的临床反应及脊柱融合情况。结果 术后存在一定的排斥反应 ,但没有明显的临床意义 ;1例出现急性深层感染 ,无晚期感染者。均未因同种异体骨移植发生疾病感染。X线观察发现术后 4个月 ,开始出现新骨 ,最后随访时 ,矫正角度平均丢失 3 4°,最小者为 - 1°,最大者为 6°。内置物无脱位、折断。结论 在治疗脊柱侧凸植骨融合时 ,采用同种异体骨移植是安全、有效的。 Objective To observe the effectiveness and safty of allograft in posterior spinal fusion in patients with scoliosis. Methods 41 cases of 54 scoliosis patients with allograft for spinal fusion were followed up. The mean followup time is 16 months. Foreign body reaction was studied clinically and fusion status was assessed radiographically. Results There was no foreign body reaction significantly in all patients. Acute deep wound infection happened in one patient and no chronic deep wound infection occurred. There was no disease transferred by allograft in followed patients. New bone formation appeared after 4 months postoperatively in radiogram. At final followup, the mean angle of 3.4° lost and minimal -1° and maximal 6°. Implants were fastened and did not loosen and fractured. Conclusions Allograft for posterior spinal fusion in scoliosis patients was useful and safe.
出处 《中华外科杂志》 CAS CSCD 北大核心 2004年第19期1178-1181,共4页 Chinese Journal of Surgery
关键词 同种异体骨融合技术 脊柱侧凸 手术治疗 临床应用 Scoliosis Spinal fusion Transplantation,homologous Followup studies
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