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重组人红细胞生成素治疗肾性贫血的疗效分析

The effectic dialysis of recombinanthuman erythropoietin
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摘要 目的:探讨不同透析方式影响重组人红细胞生成素的疗效。方法:75例病人分为血液透析、腹膜透析、无透析三组。分别在用药前后测定三组病人的贫血程度(血红蛋白、红细胞、红细胞压积)。结果:同组病人用药前与用药8周后的贫血程度有显著差异性(P<0.01),但三组之间对比无差异性(P>0.05)。结论:提示重组人红细胞生成素治疗肾性贫血有明显效果,但不同透析方式不影响其疗效。 Objective: To observe varionsly dialysis way if effect the therapent of recombinant human erythropoietin(rh - Epo). Methods: 75 patient divided into hemodiolysis adepuacydialysis and pri - dialysis, bifore and after administvation, the patient of three groups were examined in the degree of anemia(Hb. RBC. Hct. ). Results: The patient of same groups, before and after administration, there is remarkable difference either in the value of Hb, RBC, Hct of the 8th week(P<0. 01), but in the three groups have no obvione difference(P >0. 05). Conclusion: rh - EPO has significant effect for renal anemia, but variously dialysis way are do not effect the therapent of rh - EPO
出处 《中国中西医结合肾病杂志》 2000年第4期216-217,共2页 Chinese Journal of Integrated Traditional and Western Nephrology
关键词 重组人红细胞生成素 治疗 肾性贫血 疗效观察 dialysis rh - EPO curative effect
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参考文献3

  • 1Radtde Hw, Rege AB. Identification of spemine as an inhibitor of erythropoiesis in patients with chronic renal failre.J clin Invest. 1989, 67:1623-1629.
  • 2Lina VS, Degonlin RL. Recombinant human erythro poietin treatment in predialysis patients. Ahhsls of Internal medieime , 1989, 110: 108-114.
  • 3季曙明,黎磊石.应用重组促红细胞生成素治疗长期血透患者贫血[J].中华内科杂志,1993,32(2):100-102. 被引量:6

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