摘要
目的 探讨早产儿发生院内感染的危险因素 ,为院内感染的监控和干预措施提供可靠的理论依据。 方法 对我科 1991年 1月～ 2 0 0 2年 12月共 12年期间住院的 94 8例早产儿及其院内感染病例进行回顾性研究总结。 结果 94 8例早产儿中 114例发生 135次院内感染 ,发生率为9 0‰。发生院内感染者比未感染者的胎龄及出生体重均小 ,住院时间明显延长。早产儿发生院内感染的危险性相关因素为出生体重 (≤ 15 0 0g)、胎龄 (≤ 32周 )及呼吸机治疗 (P <0 .0 0 1)。以肺炎占首位 ,细菌检出率为 2 3.7% ,其中G+菌占 1/ 3,G-菌占 2 / 3。院内感染病死率为 9.6 5 %。 结论 充分了解和纠正早产儿发生院内感染的高危因素 ,强调洗手的重要性 ,合理应用抗生素 ,尽量减少侵袭性操作次数 ,缩短操作时间 ,加强消毒隔离制度和无菌原则 。
Objective To explore the risk factors of nosocomial infections of preterm infants and the management of infection control. Methods A retrospective study was made among 984 hospitalized preterm infants from Jan 1991 to Dec. 2002. Results There were 135 times mosocomial infections in 114 preterm infants The overall incidence of nosocomial infection was 9.0‰ patients days. The smaller the gestational age and birth weight, the higher the morbidity.The duration of hospitalization were longer in infected infants.The high risk factors were low birth weight (≤1500 g), small gestational age (≤32 weeks) and mechanical ventilations utilization ( P <0.001). The most common infection was pneumonia (54.8%). Bacteria were detected in 23.7% of infected cases. The mortality rate was 9.65%.Conclusion It is important to identify the high risk factors of nosocomial infections in preterm infants. The importance of hand washing and rational use of antibiotics should be enforced.
出处
《中华围产医学杂志》
CAS
2004年第5期279-282,共4页
Chinese Journal of Perinatal Medicine
