摘要
目的 评估异环磷酰胺(IFO)、足叶乙甙(Vp-16)、顺铂(DDP)联合化疗对晚期非小细胞肺癌的疗效及毒副反应。方法 用IEP方案治疗晚期非小细胞肺癌64例。结果 完全缓解(CR)6例,部分缓解(PR)27例,稳定(NC)25例,进展(PD)5例。总有效率51.6％,毒性反应主要是骨髓抑制、消化反应、脱发。结论 IEP方案治疗晚期非小细胞肺癌疗效较好,毒副反应可以耐受,可作为治疗晚期非小细胞肺癌的一线方案。
Objective To evaluate the curative and side effects of ifosfomide etoposide and cisplatine regimen for treating advanced non small cell lung cancer (NSCLC) . Methods 64 cases of advanced NSCLC were treated in our department with IEP. Results Complete remission (CR) was observed in 6 cases, PR in 27 cases, while NC in 26 cases, and PD in 5 cases, with an overall response ate of 51.6% . The main side effects were neutropenia, alopecia, gastrointestinal tract reaction. Conclusion The combined regimen of IEP for treatment in advanced NSCLC has a high response rate and tolerable side effets, it can be used as the first line regimen for treating advanced NSCLC.
出处
《实用肿瘤学杂志》
CAS
2004年第5期335-336,共2页
Practical Oncology Journal
