摘要
目的 :观察厄贝沙坦与黄芪注射液联合治疗对肾性蛋白尿的影响。方法 :将 80例慢性肾病患者分为A组 (对比组 )和B组 (治疗组 ) ,A组为常规治疗 :低盐、低蛋白饮食、控制感染、控制血压等 ;B组在常规治疗的基础上 ,给予厄贝沙坦与黄芪注射液治疗。观察治疗 1个月前后 2 4h尿量、2 4h尿蛋白定量、血肌酐、血尿素和血浆白蛋白的变化。结果 :B组治疗后 2 4h尿量明显增加 ,P <0 .0 1,有非常显著差异 ;2 4h尿蛋白减少 ,P <0 .0 5 ,有显著差异 ;血浆白蛋白增加 ,P <0 .0 5 ,有显著差异。结论
Objective: To observe the curative effect of Astragalus injection combined with irbesartan in treatment of nephrotic proteinuria.Method: 80 patients with chronic nephropathy were divided into group A(controlled group) and group B(treated group). group A consisting of 40 patients were treated with irbesartan and Astragalus injection everyday. 24 h urine excretion, 24 h urine protein quantity, plasm albumin, Scr and BUN were observed before and 1 month after therapy.Result: 24 h urine excretion was significantly increased ( P < 0.01 ), 24 h urine protein quantitate was significantly reduced( P < 0.05 ), and plasma albumin was significantly increased ( P < 0.05 ) after with treatment of irbesartan and astragalus injection.Conclusion: The therapy of irbesartan combined with Astragalus injection can significantly reduce proteinuria in the patients with chronic nephropathy.
出处
《中国药师》
CAS
2004年第9期719-720,共2页
China Pharmacist
关键词
厄贝沙坦
黄芪
蛋白尿
Irbesartan
Astragalus
Proteinuria
