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脂肪肉瘤中HSP70和mdm2与p53及Rb表达的关系 被引量：5

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作者 王亚兰 李圆圆
机构地区 重庆医科大学病理教研室
出处 《中国肿瘤临床》 CAS CSCD 北大核心 2004年第15期888-890,共3页 Chinese Journal of Clinical Oncology
基金 重庆市科委科研基金资助(编号:渝卫科技2000-50-39)
关键词 脂肪肉瘤 HSP70 MDM2 P53 RB 基因突变 基因表达
分类号 R738.6 [医药卫生—肿瘤]
  • 相关文献

参考文献16

  • 1Dahiya R, Deng G, Chen KMK, et al. p53 tumor-suppressor gene mutations are mainly localied on exon 7 in human primary and metastatic prostate cancer [J]. Br J Cancer, 1996, 74 (2):264-268
  • 2Slebos RJC, Baas IO, Clement M, et al . Clinical and pathological associations with p53 tumor-suppressor gene mutations and expression of p21 WAF1/GIP1 in colorectal carcinoma[J]. Br J Cancer, 1996, 74(2):165～ 171
  • 3Wang YL, Qiu JS, Xiong M. Relashionship between tumor suppressor p53 and tumors of adipose tissue [J]. Chinese Medical J,2001, 114(1):39-43
  • 4Gress TM, Muller-Pillasch F, Weber C, et al. Differential expression of HSPs in pancreatic carcinoma [J]. Cancer Res, 1994,54(2):547-551
  • 5Shimizu M, Saiton Y, Itoh H. Immunohistochemical staining of Ha-ras oncogene product in normal, benign and malignant human pancreatic tissues[J]. Hum Pathol, 1990, 21 (6):607 - 612
  • 6Maki CG, Huibregtse JM, Howley PM. In vivo ubiquitination nd proteasome-mediated degradation of p53 [J]. Cancer Res,1996, 56(11): 2649-2654
  • 7Scolnick DM, Chehab NH, Stavridi ES, et al. CREB-binding protein and p300/CBP-associated are transcriptional coactivators of the p53 tumor suppressor protein[J]. Cancer Res, 1997, 57(17):3693 -3696
  • 8Xiao ZX, Chen J, Levine AJ, et al. Interaction between the retinoblastoma protein and the oncoprotein in MDM2 [J]. Nature,1995, 375(6533):694-698
  • 9Martin K, Trouche D, Hagemeier C, et al. Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein [J]. Nature,1995, 375(6533):691- 694
  • 10Iwaya K, Tsuda H, Fujita S, et al. Natural state of mutant p53protein and heat shock protein 70 in breast cancer [J]. Lab Invest,1995, 72(5): 707-714

二级参考文献10

共引文献77

同被引文献46

  • 1高松源,钱碧云,陈华,刘岩雪.非霍奇金淋巴瘤中p53、MDM2表达与组织学类型及预后的关系[J].中国肿瘤临床,2004,31(13):764-766. 被引量：2
  • 2王晓玫,陶凤华,成志强,单军,苏学劲,王玲.结直肠癌MDM2基因表达与生物学行为的关系[J].第四军医大学学报,2003,24(15):1356-1358. 被引量：8
  • 3张珊文,肖绍文,刘长清,孙艳,苏星,李东明,徐刚,朱广迎,徐博.头颈鳞癌基因治疗结合放射治疗的临床研究[J].中华肿瘤杂志,2005,27(7):426-428. 被引量：24
  • 4肖绍文,颜博,吕有勇,杨敬贤,杨新宇,张珊文.野生型p53基因转染对人胃癌细胞的作用[J].中国血液流变学杂志,2006,16(1):4-6. 被引量：4
  • 5Preudhomme C,Fenaux P.The clinical significance of mutations of the p53 tumor suppressor gene in haematological malignancies[J].Br J Haematol,1997,98(3):502-511.
  • 6Swisher SG,Roth JA,Komaki R,et al.Induction of p 53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy[J].Clin Cancer Res,2003,9(1):93-101.
  • 7Mineta H,Borg A,Dictor M,et al.p53 mutation but not p53 expression,correlates with survival in head and neck squamous cell carcinmo[J].Br J Cancer,1998,78(8):1084-1090.
  • 8Baker SJ,Fearon ER,Nigro JM,et al.Chromosome 17 deletions and p53 gene mutations in colorectal carcinomas[J].Science,1989,244(4901):217-221.
  • 9Ganjavi H,Gee M,Narendran A,et al.Adenovirus mediated p 53 gene therapy in pediatric soft tissue sarcoma cell lines:sensitization to cisplatin and doxorubicin[J].Cancer Gene Ther,2005,12(4):397-406.
  • 10Xu L,Pirollo KF,Chang EH.Transferrin liposome mediated p53 sensitization of squamous cell carcinoma of the head and neck to radiation in vitro[J].Hum Gene Ther,1997,8(4):467-475.

引证文献5

二级引证文献36

中国肿瘤临床
2004年 第15期

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