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CYPHER药物洗脱支架治疗支架内再狭窄的临床疗效 被引量:2

Rapamycin-Eluting Stents for the Treatment of In-Stent Restenosis
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摘要 目的 :探讨CYPHER药物洗脱支架治疗支架内再狭窄的经验及临床疗效。方法 :9例支架内再狭窄患者接受了 12枚CYPHER药物洗脱支架治疗 ,其中右冠状动脉病变 4例 ,前降支病变 7例 ,左旋支病变 1例。结果 :12处支架内再狭窄病变均成功放置药物支架 ,手术成功率 10 0 %。所有患者临床症状明显改善 ,无并发症发生。所有患者于术后 6个月复查冠状动脉造影 ,无一例发生再狭窄。结论 :CYPHER药物洗脱支架治疗支架内再狭窄安全、有效。 Objective: To investigate the experience and efficacy of rapamycin-eluting stents in the treatment of in-stent restenosis. Methods: Nine patients who were angiographically diagnosed as having in-stent restenosis were implanted 12 rapamycin-eluting stents, 4 in the right coronary,7 in the left anterior descending, and one in the left circumflex. Results: The success rate of the procedure was 100%. Clinical symptoms were obviously ameliorated in all patients,and no severe complication was found.All patients received coronary angiography 6 months after procedure and no in-stent restenosis was noted. Conclusion: Rapamycin-eluting stent implantation can be considered safe, efficacious and feasible in the treatment of in-stent restenosis.
出处 《中国循环杂志》 CSCD 北大核心 2004年第3期178-179,共2页 Chinese Circulation Journal
关键词 支架 再狭窄 药物洗脱支架 雷帕霉素 Stent Restenosis Drug-eluting stent Rapamycin
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  • 1Lefevre T,Louvard Y,Morice MC,et al.In-stent restenosis:Should we stent the stent? A single center prospective study.Circulation,1997,96:1-88.
  • 2Morice MC,Serruys PW,Sousa JE,et al.A randomized comparision of a sirolimus-eluting stent with a standard stent for coronary revascularization.N Engl J Med,2002,346:1773-1780.
  • 3Moses JW,Shaughnessy C,Caputo R,et al.The US multiceter,randomized,double-blind study of the sirolimus-eluting stent in coronary lesions:safety outcomes at 9 months.Eur Heart J ,2002,23 (Suppl):264.
  • 4Degertekin M,Regar E,Smits PC,et al.Sirolimus-eluting stent for treatment of in-stent restenosis: the first European clinical experience.Eur Heart J,2002,23 (Suppl) :265.
  • 5Degertekin M,Saia F,Lemos PA,et al.Sirolimus-eluting stents for the treatment of in-stent restenosis.Minerva Cardioangiol,2003,51: 475-484.

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