摘要
目的 探讨以白芨微球行门脉栓塞 (TPI)联合肝动脉栓塞术 (TAE)对兔移植性肝癌门脉癌栓的治疗作用。方法 种植VX2瘤株的大白兔 3 0只 ,随机分为三组 ,采用三种方法治疗 ,对比观察疗效。结果 对照组、TAE组及TAE +TPI组 :肿瘤生长率分别为 45 .7%、-3 .3 %及 -81.8% ;肝内转移率分别 10 0 %、60 %及 0 % ;门脉主干癌栓的发生率分别为 90 %、70 %及 10 %。结论 TAE +TPI是一种有效地防治肝癌及门脉癌栓的方法 ;
Objective To study the effect of transcatheter arterial embolization (TAE) combined with transportal Bletilla microspheres injection (TPI) in treatment of transplanted liver neoplasms and portal vein tumor thrombus in rabbits. Methods Thirty white rabbits bearing VX2 transplanted tumor were randomly divided into three groups, each group was treated with different methods and the results were comparative studied. Results The tumor growth rate (GR) of the control group, TAE group and TAE+TPI group was 45.7%, -3.3% and -81.8%, respectively. The occurrence rate of intraparenchymal metastasis was 100%, 60%, 0%, and of portal vein tumor thrombus (PVTT) was 90%, 70%, 10%, respectively. Conclusion The TAE+TPI is an effective method in prevention and treatment of liver neoplasms and PVTT. Bletilla microspheres may be a useful potential peripheral portal vein embolizing agent.
出处
《中国医学影像技术》
CSCD
2004年第7期1006-1009,共4页
Chinese Journal of Medical Imaging Technology
关键词
肝肿瘤
瘤栓
门脉
治疗
栓塞
白芨微球
碘油
动物
实验性
Liver neoplasms
Tumor thrombus, portal vein, therapy
Embolization
Bletilla microspheres, iodine
Animals, laboratory
