摘要
目的 通过经颅多普勒超声 (TCD)及颈部血管彩色超声 (CDFI)联合检查对血管性帕金森综合征 (VP)和帕金森病 (PD)不同结果的对比分析 ,进一步探讨VP和PD的发病机制。方法 以 2 9例血管性帕金森综合征和 30例帕金森病为对象 ,2组患者均行TCD检查及CDFI检查。以颈动脉内膜厚度、斑块情况、狭窄程度的超声分级作为评价颈动脉硬化程度的指标。结果 VP组TCD异常率为 5 5 .17% ,PD组为 35 .18% ,2组的异常率有显著性差异 (P <0 .0 5 )。CDFI也显示 2组的动脉硬化斑块致血管狭窄程度分级间有显著性差异 (P <0 .0 5 )。结论 采用TCD及CDFI联合检查有助于鉴别VP、PD ,可揭示二者不同的脑血流动力学改变 ,为进一步探讨VP、PD发病机制提供临床依据。
Objective To analyze the results of transcranial Doppler (TCD) and color Doppler flow imaging (CDFI) on the patients with idiopathic Parkinson's disease (PD) and vascular Parkinson's syndrome (VP) and to better understand the pathogensis of the two diseases.Methods 29 cases of VP and 30 cases of PD were evaluated by TCD and CDFI.Results The abnormality rate was 55.17% in VP and 35.18% in PD by TCD, the difference in abnormality rate was significant(P<0.05). CDFI also revealed obvious difference in the degree of narrowing of the carotid artery caused by atherosclerotic plaque(P<0.05).Conclusion Combined use of the two techniques helps to differentiate VP from PD, and provides clinical evidence to better understand the changes in cerebral hemodynamics in connection with the pathogenesis of the two Parkinsonian disorders.
出处
《徐州医学院学报》
CAS
2004年第4期353-356,共4页
Acta Academiae Medicinae Xuzhou
