摘要
目的 测定中国成年男子主要器官、组织中元素浓度。方法 在我国 4个不同膳食类型地区补充采集 2 1例急死正常尸体肌肉、肋骨、肝、肾、肺、甲状腺、心、胃、脾和小肠样品 ,连同过去31例尸体采集的样品 ,采用ENAA、INAA、ICP AES和ICP MS方法及必要质控措施 ,共测定 37种元素浓度。结果 获得了我国成年男子这些器官、组织样品中 37种元素浓度。结论 除改善I在甲状腺和 33种元素在其他 5种器官、组织过去报道结果代表性外 ,本研究首次获得我国这些元素在心、胃、脾与小肠和Be、Cl、S、I在除甲状腺中I以外 10种器官、组织浓度资料。这些结果为确定中国成年男子器官、组织元素浓度背景值和中国参考人及生物动力学模型相应参数提供较前更为系统和代表性依据。
Objective To determine elemental concentrations in main organs or tissues of Chinese adult man. Methods Muscle,rib,liver,kidney,lung,thyroid,heart,stomach,spleen and small intestine samples were obtained in autopsy from 21 supplemental subjects died suddenly,who were healthy,normal before death and lived in 4 different areas with different dietary types in China.The concentrations of 37 elements in these samples together with those in samples of 31 subjects collected in the past were analyzed by ENAA,INAA,ICP-MS,ICP-AES technique and necessary QC measures. Results Concentrations of the 37 elements in these organ or tissue samples for these Chinese adult men were obtained. Conclusion Besides making results better representative than past reported results for I in thyroid and 33 elements in other 5 kinds of organs or tissues,this research obtained the data on concentrations of both these elements in heart,stomach,spleen,small intestine and Be,Cl,S,I in 10 kinds of organs and tissues (except I in thyroid) for the first time in China.These results provide more systematic and representative basis for developing concentration background values of these elements in organs or tissues of Chinese adult man,related parameters for both Chinese Reference Man and bio-kinetic models than before.Furthermore,the results have been compared with recent literature data and the newly estimated values for ICRP Reference Man.
出处
《中华放射医学与防护杂志》
CAS
CSCD
北大核心
2004年第3期211-216,共6页
Chinese Journal of Radiological Medicine and Protection
基金
国家自然科学基金资助项目 ( 3 9970 2 3 4)
