摘要
作者应用氢气呼吸试验法(BHT)测定非溃疡性消化不良(NUD)患者45例的小肠传递时间(SBTT),并与健康志愿者32名对比。结果显示,NUD组SBTT平均为116.6±31.2 min,较正常对照组(80.6±28.3 min)显著延长(P<0.01)。SBTT延迟主要与上腹饱胀、反酸暧气有关;对其中SBTT延迟患者18例进行吗丁啉治疗前后观察,经治2周后,各组SBTT均较治疗前显著加快(P<0.05)。综上提示,NUD患者有SBTT延长,小肠运动功能障碍可能是其发病机理之一。
Small bowel transit time (SBTT) was detected in 45 patients with non-ulcer dyspepsia (NUD) and 32 normal volunteers using breath hydrogen test (BHT). The mean value of SBTT in NUD patients were longer than that in normal subjects (116. 6±31. 2 min vs 80. 6±28. 3 min, respectively, P<0. 01). The prolongation of SBTT was chiefly related to epigastric satiety, acid regurgitation and ructation. Eighteen patients with long SBTT were treated with domperidone, two weeks later the SBTT in all cases were shortened compared to pre-treatment (P<0.05). The results indicate that NUD has some relation to SBTT prolongation; perhaps, the disfunction of small bowel movement is the pathogensis in NUD.
出处
《第四军医大学学报》
1993年第6期449-451,共3页
Journal of the Fourth Military Medical University
关键词
消化不良
小肠传递时间
呼吸功能
dyspepsia
small bowel transit time
respiratory function tests
domperidone
