摘要
目的 :评价相对脑血流率 (rCBF)在脑胶质类肿瘤病理分级中的价值。方法 :对 18例脑胶质类肿瘤患者术前行MR灌注成像 ,序列采用GRE EPI ,经去卷积法及运用AIF后获得相对脑血容量 (rCBV )、rCBF图。计算出最大rCBV、rCBF后 ,与病理学分级进行对照分析。结果 :高、低度恶性胶质类肿瘤的rCBV值分别为 6.19、1.76,rCBF值分别为 6.5 8、1.62 ,高、低度恶性胶质类肿瘤之间的rCBV或rCBF值差异均有显著性意义 (t检验 ,P <0 .0 1)。另外 ,rCBV、rCBF间有高度相关性 (r =0 .911,P <0 .0 1)。结论 :除rCBV外 。
Objective:To assess the value of rCBF in assessing the histophathologic grade of cerebral gliomas. Methods: 18 patients with proven cerebral gliomas were studied preoperatively, using a first pass Gd DTPA T 2 weighted echoplanar perfusion sequence. The perfusion data were deconvoluted, with an arterial input function(AIF),to obtain a color map of rCBV and rCBF. The student t test was used to determine if there was a statistical difference between the mean values of rCBV or rCBF in high grade gliomas and in low grade gliomas. Results: The mean of the rCBV was 6.19 in the high grade gliomas and 1.76 in the low grade gliomas. The mean of the rCBF was 6.58 in the high grade gliomas and 1.62 in the low grade gliomas.A significant difference in each rCBV and rCBF was found between the high and low grade gliomas ( t test, P <0.01).Additionally, there was a strong correlation between the rCBV and rCBF ( r =0.911; P < 0.01). Conclusion:A rCBF, besides a rCBV, can be a useful tool in the evaluation of the histopathologic grade of cerebral gliomas.
出处
《放射学实践》
2004年第6期392-394,共3页
Radiologic Practice
