摘要
目的:探讨健康教育及行为环境保护对三硝基甲苯(trinitrotoluene,TNT)慢性职业损害的影响。方法:对177名作业工人进行健康教育;检查144人下班洗浴后皮肤TNT残留情况,检测32名志愿者口服维生素C对尿中三硝基甲苯及主要代谢产物2,6-二硝基-4-氨基甲苯(2.6-dinitro-4-amino-toluene,DNAT)指标。结果:作业人员下班洗浴后皮肤TNT残留检出率明显下降,干预前、干预后1周、干预后3周下班洗浴后皮肤TNT阳性检出率分别为45.9%,35.6%,13.8%,差异有显著性意义(χ2=44.2,P<0.01);尿中TNT及DNAT均呈降低的趋势(P<0.01);志愿者口服维生素C后,尿TNT含量呈上升趋势,尿DNAT含量呈下降趋势。结论:健康教育是预防TNT慢性中毒有效的方式方法。在现有生产条件下,预防TNT职业危害应采取综合性措施。
AIM:To explore the effect of health education and behavior environmental prote ction on trinitrotoluene(TNT) chronic occupational diseases. METHODS:Totally 177 workers received the health education,and the remnants of TNT on the skin of the 144 exposed workers after work and shower bath were exami ned.The contents of TNT and main metabolite 2,6-dinitro-4-amino-toluene(DNAT ) in urine were measured in 32 volunteers taking vitamin C orally. RESULTS:The positive rate of TNT on the skin decreased obviously,the positive rates before intervention,1 and 3 weeks after intervention were 45.9%,35.6%and 13.8%,respectively,and the differences were significant(χ2=44.2,P< 0.01);and the contents of TNT and DNAT in urine showed a decreasing tendency(P< 0.01).Afte r taking vitamin C orally,the contents of TNT in urine were increased,but the co ntents of DNAT were decreased. CONCLUSION:Health education is an effective way and means to prevent the TNT c hronic poisoning.In order to prevent TNT occupational diseases,a series of compr ehensive measures should be adopted in the present situations.
出处
《中国临床康复》
CSCD
2004年第15期2857-2859,共3页
Chinese Journal of Clinical Rehabilitation
基金
2000年美国中华医学基金会
美国健康基金会联合资助项目~~
