摘要
目的:分析重组人脑利钠肽治疗慢性心力衰竭急性发作的临床治疗效果。方法:回顾性分析100例慢性心力衰竭急性发作的患者,随机分为两组,即对照组50例和观察组50例,对照组采用基础治疗方法,观察组在对照组治疗的基础上加用基因重组人脑利钠肽,将两组的治疗效果进行统计学比较分析,观察两组治疗后的不良反应。结果:对照组的总有效率为72.0%,观察组的总有效率为92.0%,将两组的总有效率经统计学比较,结果显示P<0.05,表明观察组疗效显著强于对照组,同时观察组不良反应发生率低。结论:基因重组人脑利钠肽治疗慢性心力衰竭急性发作疗效显著,具有安全、有效、不良反应少的优点,值得临床推广使用。
Objective To analyze the clinical therapeutic effect of recombinant human brain natriuretic peptide in treatment of acute attack of chronic heart failure.Method A total of 100 cases of patients with acute exacerbation of chronic heart failure from Jan 2011 to Jan 2012 in our department were retrospectively analyzed,and they were randomly divided into two groups.The control group was 50 cases and observation group was 50 cases,The control group was treated by basic treatment method,observation group was added with natriuretic peptide based on the treatment in control group,the treatment effect of the two groups were statistically analyzed,adverse reactions of the two groups after treatment were observed.Results The total efficiency of the control group was 75.4%,the total effective rate of observation group was 89.3%,the total effective rate of two groups was compared,The results showed that P<0.05,effect of the observation group was significantly stronger than that in control group,At the same time,the observation group had low incidence of adverse reactions.Conclusion Brain natriuretic peptide has great effect in the treatment of acute exacerbation of chronic heart failure,and it is safety,effective,with fewer adverse reactions,so it is worthy of clinical using.
出处
《吉林医学》
CAS
2013年第13期2415-2416,共2页
Jilin Medical Journal
关键词
基因重组人脑利钠肽
慢性心力衰竭
临床疗效
Recombinant human brain
Natriuretic peptide
Chronic heart failure
Clinical curative effect
