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MEMS微针阵列及其在生物医学上的应用 被引量:11

Application of MEMS Microneedles Array in Biomedicine
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摘要 利用微机械技术制作的 MEMS微针阵列是 MEMS技术在生物医学上一个重要应用 ,它为生物医学领域提供了新的医疗手段。微针技术在精确药物注射、临床监测、生化检测等领域有着广泛的发展前景。本文介绍了MEMS微针阵列在生物医学领域的三个方面的重要应用 :生物医学微针电极、经皮药物传输及流体采样 ,对他们的应用原理和当前的最新技术进展进行了概述 ,说明了 MEMS微针应用的特点 ,它为患者提供了无痛、高效、安全的医疗手段 ,更符合医学研究人性化的特点。另外 ,讨论了微针阵列制作的一系列工艺方法。 Microneedles array based on micro electro-mechanical system (MEMS) technology is one of important applications in biomedicine and brings a new means in biomedicine field. The prospect for the development of microneedles technology in precision drug injection, clinical monitoring and biochemistry test is and save broad. This paper describes three important applications of MEMS microneedles array in biomedicine field: biomedicine microneedles electrode, transdermal delivery of drugs and fluid extraction, and then summarizes their application elements and recent development. It explains the characteristics of microneedles, which provide painless, effective and save biomedical method in accordance with human requirements. In addition, a series of the fabrication technology of microneedles array is discussed.
出处 《生物医学工程学杂志》 EI CAS CSCD 2004年第3期482-485,共4页 Journal of Biomedical Engineering
基金 国家自然科学基金资助项目 ( 2 983 3 0 70 ) 国家重点基础研究发展规划项目"集成微光机电系统研究"资助项目 ( G19990 3 3 10 6)
关键词 微针阵列 微电极 药物传输 流体采样 生物医学 微机电系统 MEMS Microneedles arrary Microelectrode Drug delivery Fluid extraction
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参考文献8

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