摘要
目的探讨血清HBsAg(+)且HBV-DNA含量大于1000拷贝/mL患者尿液乙肝病毒DNA与血清ALT含量的关系。方法应用荧光定量聚合酶链反应(FQ-PCR)检测32例患者(血清HBsAg(+)且HBV-DNA含量大于1000拷贝/mL)尿液的HBV-DNA,与其血清HBV-DNA比较,并分析与ALT的关系。结果尿液HBV-DNA与血清HBV-DNA存在正相关关系(r=0.797,P<0.01),尿液HBV-DNA与ALT有正相关关系(r=0.655,P<0.01)。结论血清中乙肝病毒拷贝数越大,尿液检出率也越大且与其ALT含量呈正相关。HBV-DNA高拷贝的患者更要注意尿液的传染性。
Objective To investigate the correlation between HBV-DNA(>1000 copies/mL content) in urine of patients with serum HBsAg(+) and ALT in serum.Methods HBV-DNA(>1000 copies/mL content) in urine of 32 cases with serum HBsAg(+) were detected by FQ-PCR.And urine HBV-DNA was compared with ALT in serum.Results There was a straight line correlation of HBV-DNA between in urine and in serum;and the correlation between HBV-DNA in urine and ALT in serum.Conclusion HBV-DNA in urine had well relevance with HBV-DNA in serum.More attention should be paid to the infectious urine for patients with high HBV-DNA in serum,and the correlation existed between HBV-DNA in urine and ALT in serum.
出处
《分子诊断与治疗杂志》
2009年第4期243-244,共2页
Journal of Molecular Diagnostics and Therapy
