摘要
Objective:To research the anti-inflammatory and antioxidation effect of atorvastatin and probucol joint therapy on patients with acute coronary syndrome.Methods:228 patients with acute coronary syndrome were enrolled and randomized to atorvastatin group(atorvastatin 10 mg/d,n=120)and joint therapy group(atorvastatin 10 mg/d and probucol 0.25 g,2/d,n=108).The serum total cholesterol,low density lipoprotein cholesterol,hs-CRP and oxLDL level were measured before and 1 month after the therapy.Results:The indexes were no difference between the two groups before the therapy but significant difference 1 month after the therapy.Conclusion:Compare with atorvastatin alone,the joint therapy with probucol can give better anti-inflammatory and antioxidation effect and than better prognosis.
Objective:To research the anti-inflammatory and antioxidation effect of atorvastatin and probucol joint therapy on patients with acute coronary syndrome.Methods:228 patients with acute coronary syndrome were enrolled and randomized to atorvastatin group(atorvastatin 10 mg/d,n=120)and joint therapy group(atorvastatin 10 mg/d and probucol 0.25 g,2/d,n=108).The serum total cholesterol,low density lipoprotein cholesterol,hs-CRP and oxLDL level were measured before and 1 month after the therapy.Results:The indexes were no difference between the two groups before the therapy but significant difference 1 month after the therapy.Conclusion:Compare with atorvastatin alone,the joint therapy with probucol can give better anti-inflammatory and antioxidation effect and than better prognosis.
出处
《心肺血管病杂志》
CAS
2010年第S1期65-66,共2页
Journal of Cardiovascular and Pulmonary Diseases
