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原子吸收光谱法测定氨苄西林钠和美洛西林钠 被引量:3

Determination of Ampicillin Sodium and Mezlocillin Sodium by Atomic Absorbption Spectrometry
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摘要 基于氨苄西林钠和美洛西林钠分子中含钠元素 ,通过原子吸收光谱法测定钠的含量 ,可测得药品中氨苄西林钠和美洛西林钠的含量 .氨苄西林钠和美洛西林钠的浓度分别为 0 .81~ 5 .6 5 μg/mL和 0 .82~ 1 2 .33μg/mL时与吸光度呈线性关系 ,检出限分别为 4 .99μg/mL和 7.93μg/mL ,精密度分别为 0 .84 %和 2 .93% ,回收率分别为 97.5 %~ 95 .0 %和 95 .5 %~ 1 0 5 .0 % . Due to Ampicillin Sodium and Mezlocillin sodium molecules contain Sodium element, We can measure the content of Sodium by the atomic Absorption Spectrometry,to measure the content of Ampicillin Sodium and Mezlocillin sodium in medicine,respectwely. The linear calibration range ampicillin sodium and Mezlocillin sodium is 0.81~5.65μg/mL and 0.82~12.33μg/mL respectively, with detection limits of 4.99μg/mL respectively, and 7.93 μg/mL, and the relative standard deviation is 0.84% and 2.93% , respectively. The recovery is 97.5%~95.0% and 95.5%~105.0% ,respectively.
出处 《雁北师范学院学报》 2003年第5期46-47,共2页 Journal of Yanbei Teachers College
基金 雁北师范学院科学研究基金 (2 0 0 30 4 1 0 2 )
关键词 氨苄西林钠 美洛西林钠 原子吸收光谱法 测定 ampicillin sodium mezlocillin sodium atomic absorption spectrometry measurement
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  • 1张维民.国内新药文献指南(第一分册)(西药部分)[M].北京:中医古籍出版社,1995.297.
  • 2-.美国药典.ⅩⅩⅢ[M].,1994.专题1024.
  • 3张维民,国内新药文献指南.1,1995年,297页
  • 4WS-131(X-108)-93 (试行).

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  • 1中华人民共和国药典委员会.中华人民共和国药典(二部)[M].北京:化学工业出版社,2000.1025-1052.
  • 2Betriu C, Sanchez A, Gomez M et al.J Antimicrob Chemother, 1999. 43:133.
  • 3Garcia-Glez J C, Mendez R, Martfn-Villacorta J. J Chromatogr A, 1998, 812(1-2): 213.
  • 4Colaizzi P A, Coniglio A A, Poynor W J et al.Antimicrob Agents Chemother, 1986, 30(5): 675.
  • 5McCloskey R V, LeFrock J L, Smith B R et al. Phamacotherapy, 1982, 2(6): 300.
  • 6中华人民共和国药典委员会.中华人民共和国药典(二部)[M].北京:化学工业出版社,2000.517.
  • 7BETRIU C, SANCHEZ A, GOMEZ M, et al. In-vitro susceptibilities of the bacteroides fragilis group to newer β -lactam agents[ J]. The Journal of Antimicrob Chemother, 1999, 43( 1 ) : 133 - 136.
  • 8GARCIA-GLEZ J C, MENDEZ R, MARTIN-VILLACORTA J.Determination of piperacillin and mezlocillin in serum and urine by high-performance liquid chromatography after derivatisation with 1,2,4-triazole[ J ].Journal of Chromatography A. , 1998,812( 1 - 2) : 213 - 220.
  • 9ARZUAGA A, ISLA A R, GASCON J, et al.Quantitation and stability of piperacillin and tazobactam in plasma and ultratrate from patients undergoing continuous venovenous hemofiltration by HPLC [ J ]. Biomedical Chromatography,2005,19(8) :570-578.
  • 10COLAIZZI P A, CONIGLIO A A, POYNOR W J, et al.Comparative pharmacokinetics of two multiple-dose mezlocillin regimens in normal volunteers[ J ].Antimicrob Agents Chemother, 1986, 30(5) : 675 - 678.

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