摘要
目的 分析江苏省启东市1972-2005年癌症发病谱,为癌症控制服务.方法 在约110万人口规模的启东地区建立以人群为基础的癌症登记报告系统,1972-2005年期间报告各种癌症发病病例70646例,用国际疾病分类第10版(ICD-10)进行分类编码,用发病率(CR)、标化率(ASR)对资料进行常规描述分析,用变化百分比(PC)、年均变化百分比(APC)、时期和出生队列方法进行发病趋势分析.结果 启东市:1972-2005年各种癌症年均发病率为184.77/10万,ASR为109.32/10万,其中男、女性发病率(ASR)分别为239.22/10万(136.08/10万)和131.58/10万(79.26/10万).启东居民发生癌症的终生累积危险为16.31%(男女分别为21.62%与11.1l%).启东前10位癌症部位(CR)分别为肝癌(60.69/10万)、胃癌(32.97/10万)、肺癌(27.59/10.万)、食管癌(9.34/10万)、直肠癌(8.06/10万)、乳腺癌(6.48/10万)、胰腺癌(5.97/10万)、白血病(3.84/10万)、脑(CNS)肿瘤(3.43/10万)、结肠癌(2.93/10万).乳腺癌(12.59/10万)和宫颈癌(4.62/10万)分别位居女性主要癌症的第4位和第8位.所有癌症中,肝癌占32.84%,消化系统癌症占65.85%.癌症粗发病率有逐年上升的趋势,PC和APC分别为87.19%和1.85%,但ASR却显示下降的趋势,PC和APC分别为-12.14%和-0.51%.ASR有显著上升趋势的癌症包括肺癌、乳腺癌、结直肠癌,有显著下降的包括胃癌、食管癌等.出生队列分析显示35岁以下青年人肝癌发病率、40岁以上人群的胃癌发病率、45岁以上人群的膀胱癌和50岁以上人群的食管癌发病率下降趋势明显.30岁以上人群的肺癌发病率、45~59岁人群的胰腺癌发病率以及40岁以上女性乳腺癌的发病率均有上升趋势.结论 启东市34年人群癌症登记资料的分析研究,显示了主要癌症的发病谱和流行趋势,提示了主要癌症的病因线索和癌症防治的重点.
Objective To explore the patterns of cancer incidence from 1972 to 2005 in Qidong,Jiangsu province.Methods A population-based cancer registration system was established in Qidong region with 1.1 milions residents to colleet data of cancer incident cases.70646 cases were registered during the years from 1972 to 2005,and ICD-10 was administrated for classification and coding,and crude rate(CR)and age-standardized rate(ASR),percent change(PC),annual percent change(APC)were caleulated using annual data on population size.Changes within age groups for different periods of incidence,and for different years of birth(birth cohort)for the leading sites of cancers were analyzed.Results The average annual incidence for cancers during the years of 1972-2005 was 184.77 per 100000(ASR:109.32 per.100000),of which,the incidence for male was 239.22(ASR:136.08),and 131.58(ASR:79.26)per 100000 for female.The cumulative risk of cancer occurrence was 16.31%(21.62%in males,and 11.11%in females).The most common leading sites in rank in this area were liver(CR:60.69 per 100000),stomach(32.97),lung(27.59),oesopagus(9.34),rectum(8.06),breast(6.48),pancreas(5.97),leukaemia(3.84),bran and CNS(3.43),and colon(2.93).Female breast cancer(12.59)and cervix cancer(4.62)were the forth and the eighth in rank among all sites for women.Liver cancer accounted for almost one third(32.84)of the maligmancies.Furthermore,the cancers from digestive organs accounted for 65.85%of all sites.CR rates were rising overal,at 87.19%for PC,and at 1.85%.for APC.The ASR,however,reduced by 12.14%for PC,and by 0.51%for APC.The rising trends were also observed for the ASR from cancers in lung,female breast,and colon-rectum,while the decreasing trends were observed for stomach and oesophagus cancer.Birth cohort analysis showed that there was a decline in ages under 35 for the incidence of liver cancer,in ages over 40 for stomach cancer,and in those aged over 45 for bladder cancer and over 50 for oesophagus cancer.Rising tyends existed for incidence rates from lung cancer in the aged over 30,pancreas cancer in aged 45-59,and female breast cancer in those aged 40 and above.Concusion Monitoring of cancer incidence rates through population-based cancer registration in 34 years did help to show the burden and patterns of main cancer sites and time trends,which provides some references to future aetiological study,and policy making on cancer control in Qidong
作者
陈建国
朱健
张永辉
陆建华
朱源荣
CHEN Jian-guo;ZHU Jian;ZHANG Yong-hui;LU Jian-hua;ZHU Yuan-rong(Department of Epidemiology,Qidong Liver Cancer Institute,Jiangsu 226200,China)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2007年第S01期47-55,共9页
Chinese Journal of Preventive Medicine
关键词
肿瘤
数据收集
疾病分类
发病率
评价研究
Neoplasms
Data collection
lassifcation
Incidence
Evaluation studies
