摘要
目的探讨开封县居民恶性肿瘤死亡率的动态变化趋势,为肿瘤防治研究提供依据.方法资料取自河南省开封县肿瘤登记报告办公室1988-2005年恶性肿瘤死亡资料(共计9543例,其中男5976例,女3567例),用世界标准人口计算每2年合并资料的标化死亡率(标化率),标化死亡率年均变化百分比用对数线性回归计算.结果开封县居民恶性肿瘤年均死亡率男性为95.09/10.万,标化率为117.41/10万;女性死亡率为59.13/10万,标化率为57.15/10万.开封县1988-1989年至2004-2005年恶性肿瘤标化死亡率的比较显示:男、女性所有部位肿瘤标化死亡率变动趋势不明显;但男性肺癌、肝癌和女性乳腺癌标化死亡率上升趋势显著,年均增加6.54%、5.07%和7.04%.同时,男、女性食管癌年降幅为7.09%和13.53%,呈显著下降趋势.其他部位肿瘤标化死亡率分别有不同程度的波动,但变化幅度均未达显著性水平.结论近20年来,开封县部分常见恶性肿瘤死亡率有显著的时间变动趋势,应开展流行病学研究,探索影响肿瘤死亡率变动的危险因素.
Objective To investigate the time trends of cancer mortality among residents in Kaifeng county,Henan province.Methods Data on cancer mortality from the vital registration system in Kaifeng county from 1988 to 2005 was analyzed.A total of 9543 death records(5974 males and 3567 females)due to malignant tumors were studied.A two-year period age-specified standarized mortality rates were directly adjusted by the world standard population,and the annual percentage change(APC)of mortality were estimated by a linear logarithm regression.Results The crude cancer death rate for male was 95.09/100000 and its age-standardized death rate was 117.41/100000.While,the crude cancer death rate for female was 59.13/100000 and the age-standardized death rate was 57.15/100000.There was a significant growth tread for lung cancer(APC:6.54%),liver cancer(5.07%)in males and breast cancer(7.04%)in females in the groups aged over 18.On the contrary,the decreasing treads for esophageal cancer in both of sexes(-7.09%,-13.53%)were also observed in this study.Meanwhile,there was no other significant changes in the trend,either in the tumor sites or mortality,was observed.Conclusion In the past two decades,there has been a significant increasing trend for cancer mortality in Kaifeng county,of Henan Province.Hence,it is necessary to enhance epidemiological survey to identify risk factors at the earlier stages.
作者
崔亚玲
付莉
耿振新
李海冰
马师
吕全军
陆维权
杨文献
CUI Ya-ling;FU Li;GENG Zhen-xin;LI Hai-bing;MA Shi;LüQuan-jun;LU Wei-quan;YANG Wen-xian(Henan Tumor Institute,Zhengzhou 450008,China;不详)
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
2007年第S01期62-65,共4页
Chinese Journal of Preventive Medicine
关键词
肿瘤
死亡率
趋势
回归分析
Neoplasms
Mortality
Time trends
Regression analysis
