摘要
目的探讨黏液性交界性卵巢肿瘤(mucinous borderline ovarian tumor,M-BOT)的临床特点与预后。方法收集33例M-BOT患者的临床资料,分析患者的临床特征、影响预后的病理因素,并分析与肿瘤复发有关的危险因素。结果33例中,57.6%(19/33)进行了根治性手术,42.4%(14/33)进行了姑息性手术。39.4%(13/33)进行了全面分期手术。随访70(10~130)个月,随访率87.9%,全部病例复发11例(33.3%,11/33),与肿瘤相关死亡2例(6.1%,2/33)。单因素分析显示患者FIGO分期、手术方式与复发有关(P<0.05),但多因素分析结果显示2因素均不是肿瘤复发的独立危险因素(95%CI:0.115~1.369和0.763~11.93)。结论M-BOT患者预后较好,进展期患者复发率高,对于有生育要求的早期患者,可以选择保守性手术。
Objective To explore the relationship between the clinical features and prognosis of mucinous borderline ovarian tumors(M-BOTs).Methods The clinical data on 33 patients with M-BOTs was collected before the clinical features,pathological factors affecting prognosis and risk factors for tumor recurrence were analyzed retrospectively.Results All the patients underwent surgery as the initial treatment,19 of whom(57.6%)underwent a radical procedure,and 14(42.4%)underwent conservative surgery.Of these 33 patients,13(39.4%)underwent a staging procedure.With an average follow-up of 70 months(ranging from 10 to 130 months),the follow-up rate was 87.9%.Tumor recurred in eleven of these patients(33.3%,11/33)and 2 cases(6.1%,2/33)died of tumor progression.Univariate analysis showed that FIGO staging and types of surgical procedures were factors that influenced recurrence(P<0.05),but multivariate analysis showed that advanced FIGO staging(95%CI 0.115-1.369;P>0.05)and conservative surgery(95%CI 0.763-11.93;P>0.05)were not independent risk factors.Conclusions The majority of patients with M-BOTs have a favorable prognosis.Recurrence is more likely in patients with later-stage disease.Conservative surgery can be an option for early-stage patients who hope to remain fertile.
作者
刘芳
徐培培
周雪梅
杜克容
LIU Fang;XU Peipei;ZHOU Xuemei;DU Kerong(Department of Gynaecology and Obstetrics,Sichuan Armed Police Hospital,Leshan 614000,China)
出处
《武警医学》
CAS
2021年第7期595-599,共5页
Medical Journal of the Chinese People's Armed Police Force
