摘要
目的探胺碘酮在院前急救中预防性应用治疗急性心肌梗死的临床效果。方法研究对象选取乌鲁木齐市达坂城区人民医院2016年11月到2018年11月间收治的急性心肌梗死患者98例,采取回顾性分析的方式进行研究,根据患者院前使用的药物将其分为常规组(利多卡因)和对照组(胺碘酮),每组各49例。比较两组患者治疗前后动脉血气指标,比较两组患者平均除颤次数、平均住院天数、预后及不良事件发生情况。结果治疗前,两组患者PaO2、PaCO2比较,差异无统计学意义(P>0.05)。治疗后,两组患者PaO2、PaCO2较治疗前均有显著改善,且试验组患者PaO2、PaCO2均显著优于常规组患者,差异有统计学意义(P<0.05)。常规组患者平均除颤次数、平均住院天数均显著多于试验组患者,差异有统计学意义(P<0.05)。常规组患者抢救成功率显著低于试验组患者,常规组患者心肌梗死复发率显著高于试验组患者,差异有统计学意义(P<0.05)。常规组出现低血压1例,胸闷1例,窦性停搏1例,窦性心动过缓2例,试验组无不良反应情况发生。常规组不良反应发生率为10.20%。结论胺碘酮在院前急救中预防急性心肌梗死的临床效果确切,有效改善患者血气指标,缓解临床症状,减少不良反应发生,提高预后水平,值得在临床推广。
Objective To investigate the clinical effect of Amiodarone in the prevention of acute myocardial infarction in prehospital emergency treatment.Methods In this study,98 patients with acute myocardial infarction who were admitted at the people’s hospital of Dabancheng district of Urumqi from November 2016 to November 2018 were selected and analyzed retrospectively.The patients were divided into regular group(Lidocaine)and experimental group(Amiodarone)according to prehospital medication.The mean value of defibrillation,the average length of hospital stay,the prognosis and the occurrence of adverse events were compared between the two groups before and after the treatment.Results Before treatment,there was no significant difference in Pa O2 and Pa CO2 between the two groups(P>0.05).After treatment,Pa O2 and Pa CO2 in the two groups were significantly improved compared with those before treatment,and Pa O2 and Pa CO2 in the experimental group were significantly better than those in the conventional group,the difference was statistically significant(P<0.05).The average value of defibrillation and the average length of hospital stay in the routine group were significantly higher than those in the experimental group,and the difference was statistically significant(P<0.05).The success rate of rescue in the conventional group was significantly lower than that in the experimental group.The recurrence rate of myocardial infarction in the conventional group was significantly higher than that in the experimental group(P<0.05).In the conventional group,there were one case of hypotension,one case of chest tightness,one case of sinus arrest,and two cases of sinus bradycardia.No adverse reactions occurred in the test group.The incidence of adverse reactions in the conventional group was 10.20%.Conclusions The clinical effect of amiodarone in preventing acute myocardial infarction in pre-hospital emergency is effective.It can effectively improve the blood gas index,alleviate clinical symptoms,reduce adverse reactions and improve the prognosis.It is worthy of clinical promotion.
作者
单玉巧
SHAN Yuqiao(Department of Emergency,The People's Hospital of Dabancheng district of Urumqi,Urumqi,830039,China)
出处
《新疆医学》
2020年第7期715-717,共3页
Xinjiang Medical Journal
关键词
胺碘酮
院前急救
急性心肌梗死
临床效果
Amiodarone
pre-hospital first aid
Acute myocardial infarction
Clinical effect
