摘要
目的探讨血清总25-(OH)D对急性心肌梗死患者的临床分析。方法根据2018年1月-2020年2月在本院漯河医学高等专科学校第三附属医院消化内科治疗的急性心肌梗死患者70例和将同期进行正常体检的健康人70例作为研究对象,分别对于两组人员的临床资料进行评估,比较两组人员体内血清总25-(OH)D的缺乏程度对于不良事件的单因素分析和多因素分析。结果健康体检组的血清总25-(OH)D水平高于心肌梗死组,MCP-1、Hs-CRP、WBC、IL-6要低于心肌梗死组(P<0.05);多因素Logistic分析结果表明:急性心肌梗死患者患病原因均与年龄、高血压、糖尿病、充血性心力衰竭、恶性心律失常、非致死性心肌梗死、心原性死亡有一定关系,差异具有统计学意义(P<0.05)。结论血清总25-(OH)可作为判断临床急性心肌梗死患者患病的因素之一,患者基础性疾病和总25-(OH)D的严重缺乏是导致急性心肌梗死患者发生不良事件的主要因素,应注重临床总25-(OH)D的摄入,减少患者痛苦,值得推广应用。
Objective To investigate the clinical analysis of serum total 25-(OH)D in patients with acute myocardial infarction.Methods 70 patients with acute myocardial infarction treated in the third affiliated hospital of Luohe medical college from January 2018 to February 2020 were chosen as subjects,and 70 healthy people who underwent normal physical examinations during the same period were chosen as the control group.The clinical data between the two groups were evaluated,and the relationship between the level of total serum 25-(OH)D and adverse events between two groups were compared through univariate analysis and multivariate analysis.Results The level of total serum 25-(OH)D in healthy people was higher than that of patients with acute myocardial infarction,while the amounts of MCP-1、Hs-CRP、WBC、IL-6 were lower than those of observation group(P<0.05).The results of multivariate logistic analysis showed that the causes of acute myocardial infarction were related to age,hypertension,diabetes,congestive heart failure,malignant arrhythmia,non-fatal myocardial infarction and cardiogenic death,and the difference was statistically significant(P<0.05).Conclusion Serum total 25-(OH)D can be used as one of the indexes to determine the clinical disease of patients with acute myocardial infarction.Basic diseases and severe deficiency of total 25-(OH)D are the main causes of adverse events in patients with acute myocardial infarction.So it should be paid more attention to intake of clinical total 25-(OH)D,which can reduce the suffering of patients.it is worthy of promotion and application.
作者
杨水长
朱桂华
YANG Shui-chang;ZHU Gui-hua(The Third Affiliated Hospital of Luohe Medical College,Luohe,Henan,462000,China;The Affiliated Hospital of Xinyang Vocational and Technical College,Xinyang,Henan,464099,China)
出处
《新疆医学》
2021年第7期808-810,共3页
Xinjiang Medical Journal
关键词
血清总25-(OH)D
急性心肌梗死
预后影响
多因素分析
serum total 25-(OH)D
Acute myocardial infarction
prognostic impact
Univariate analysis
Multivariate analysis
