摘要
目的:观察蒙药毛勒日达布苏-4汤散治疗颈动脉斑块的临床疗效。方法:选取2017年3月—2019年3月在我院接受治疗的100例颈动脉斑块患者作为研究对象,随机分为蒙西药组和西药组,各50例。蒙西药组给予毛勒日达布苏-4汤散3 g/早、辛伐他汀片10 mg/晚;西药组给予辛伐他汀片10 mg/晚。疗程24周,比较两组治疗前后颈动脉斑块面积大小、血脂指标变化、斑块稳定情况。结果:两组治疗24周后与治疗前比较,颈动脉斑块面积缩小、斑块稳定,血总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)指标下降,差异有统计学意义(P<0.05)。治疗24周后蒙西药组与西药组相比颈动脉斑块面积缩小显著,颈动脉斑块稳定作用更佳,血总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)指标下降明显,差异有统计学意义(P<0.05)。结论:蒙药毛勒日达布苏-4汤散能有效缩小颈动脉斑块面积、稳定颈动脉斑块、降低血脂指标。
Objective:To investigate the clinical efficacy of Mongolian medicine Maoleri dabusi-4 powder in the treatment of carotid atherosclerotic plaque.Methods:100 patients with carotid artery plaque who received treatment in our hospital from March 2017 to March 2019 were selected as the study objects.The patients were randomly divided into Mongolian medicine group and western medicine group with 50 patients in each group.The Mongolian medicine group was given Maoleri dabusi-4 powder 3 g/morning and Simvastatin tablets 10 mg/evening,western medicine group was given with simvastatin tablets for 24 weeks.The changes of carotid plaque area,lipid profile and plaque stability before and after treatment were compared between the two groups.Results:After 24 weeks of treatment,the two groups had the effect of reducing the area of carotid artery plaque and stabilizing the plaque,total blood cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C)decreased.The difference was statistically significant(P<0.05).After 24 weeks of treatment,compared with the western medicine group,the area of carotid artery plaque in the Mongolian medicine group decreased significantly,and the stabilizing effect of carotid artery plaque was better in the western medicine group.The indicators of total blood TC,TG and LDL-C decreased significantly,with statistically significant differences(P<0.05).Conclusion:The Mongolian medicine Maoleri dabusi-4 powder can effectively reduce the area of carotid artery plaque,stabilize carotid artery plaque and reduce the blood lipid index.
作者
包英姝
都伊乐
小荣
乌仁斯琴
乌林图雅
白朝鲁
BAO Ying-shu;DU Yi-le;XIAO Rong;Wurensiqin;Wulintuya;Baichaolu(Xilingol League Mongolian Medical Hospital,Xilinhot,Inner Mongolia 026000)
出处
《中国民族医药杂志》
2020年第7期1-2,共2页
Journal of Medicine and Pharmacy of Chinese Minorities
基金
锡林郭勒盟科技局计划项目,项目编号201716
关键词
蒙药毛勒日达布苏4汤散
颈动脉斑块
辛伐他汀片
Mongolian medicine Maoleri dabusi-4 powder
Carotid plaque
simvastatin tablets
