摘要
目的:研究汉桃叶的化学成分。方法:运用D-101大孔树脂柱层析、Sephadex LH-20葡聚糖凝胶、正相硅胶柱等色谱技术进行分离,并运用MS、NMR技术对分离得到的化合物进行结构鉴定。结果:从汉桃叶的70%乙醇提取物中分离得到15个化合物,分别鉴定为:芥子醛(1)、香草醛(2)、咖啡酸乙酯(3)、(+)-syringaresinol(4)、erythro-guaiacyl-glycerol-β-coniferyl aldehyde ether(5)、ω-hydro-xypropioguaiacone(6)、5-hydroxymethyl-furfural(7)、对苯二酚(8)、3,4-dihydroxybenzaldehyde(9)、threo-1,2-bis-(4-hydroxy-3-methoxyphenyl)-propane-1,3-diol(10)、erythro-1,2-bis-(4-hydroxy-3-methoxyphenyl)-propane-1,3-diol(11)、coniferaldehyd(12)、3-表-白桦脂酸(13)、3-表-齐墩果酸(14)、kobophenol A(15)。结论:其中,化合物1、3~12、15为首次从鹅掌柴属植物中分离得到。
Objective:To study the chemical constituents from the stems and leafy stems of Schefflera leucantha.Methods:The compounds were isolated by using a combination of various chromatographic techniques,including D-101 macroporous adsorptive resins,Sephadex LH-20,silica gel and other methods.The structures were identified by the MS,NMR.Results:Fifteen compounds were isolated from the 70%ethanol extract of the stems and leafy stems of Schefflera leucantha and identified as sinapaldehyde(1),vanillin(2),caffeic acid ethyl ester(3),(+)-syringaresinol(4),erythro-guaiacyl-glycerol-β-coniferyl aldehyde ether(5),ω-hydro-xypropioguaiacone(6),5-hydroxymethyl-furfural(7),hydroquinone(8),3,4-dihydroxybenzaldehyde(9),threo-1,2-bis-(4-hydroxy-3-methoxyphenyl)-propane-1,3-diol(10),erythro-1,2-bis-(4-hydroxy-3-methoxyphenyl)-propane-1,3-diol(11),coniferaldehyd(12),3-epi-betulinic acid(13),3-epi-oleanolic acid(14),kobophenol A(15),respectively.Conclusion:Among them,compounds 1,3 to 12,15 are isolated from Schefflera genus for the first time.
作者
杨婷
李小双
黄勇
郑林
马雪
蒋礼
李勇军
YANG Ting;LI Xiao-shuang;HUANG Yong;ZHENG Lin;MA Xue;JIANG Li;LI Yong-jun(Guizhou Medical University,Engineering Research Center for Development and Application of Ethnic Medicine and Traditional Chinese Medicine,Ministry of Education/National Key Laboratory of Efficacy and Utilization of Medicinal Plants Jointly Built by the Ministry and the Province,Guiyang 550004,China;Guizhou Medical University,College of Pharmacy,Guiyang 550004,China;Guizhou Medical University,Guizhou Provincial Key Laboratory of Pharmaceutical Preparation,Guiyang 550004,China)
出处
《中药材》
CAS
北大核心
2021年第7期1631-1635,共5页
Journal of Chinese Medicinal Materials
基金
国家重点研发计划项目(2018YFC1708100)
中央引导地方科技专项项目(20184006)
贵州省科学技术厅人才团队项目(20165677)
关键词
汉桃叶
化学成分
结构鉴定
Stems or leafy steams of Schefflera leucantha R.Viguier
Chemical constituents
Structure identification
