Taking the academic association of the Federation of Life Science Research and Innovation of the College of Life Science and Biotechnology of Heilongjiang Bayi Agricultural University as the research platform,it is ne...Taking the academic association of the Federation of Life Science Research and Innovation of the College of Life Science and Biotechnology of Heilongjiang Bayi Agricultural University as the research platform,it is necessary to organically combine personalized education with the cultivation of innovative and entrepreneurial ability.On the basis of unified teaching ideas,we should pay attention to the individual differences of educational objects,eliminate the disadvantages of traditional education,and break the conventional"spoon-feeding"teaching mode.It is necessary to shift from only paying attention to one-way indoctrination to paying attention to the cultivation of students'innovative quality,and to enhance students'interest in scientific research and practical ability of innovation and entrepreneurship through the rich scientific research activities of academic associations.展开更多
With the further advancement of China’s major manned spaceflight project,the national space laboratory was successfully built.China has also made considerable progress and breakthroughs in the field of space life sci...With the further advancement of China’s major manned spaceflight project,the national space laboratory was successfully built.China has also made considerable progress and breakthroughs in the field of space life sciences.This paper reviews the related biological effects under space flight conditions,mainly including epigenetic effects,skeleton remodeling and peripheral body fluid circulation effects,as well as the research and application of space life science related biotechnology in the field of microbial culture and biological regeneration life support system.展开更多
In the past two years,China’s space life science has made great progress.Space biomedical and life science programs have carried out ground-based research for the first batch of projects,and are preparing to carry ou...In the past two years,China’s space life science has made great progress.Space biomedical and life science programs have carried out ground-based research for the first batch of projects,and are preparing to carry out space-based experiments along with the construction of China’s space station.And space life science payload of the space station completed the development of positive samples.Thus,with the development of lunar exploration and Mars exploration projects,astrobiology research has also made a lot of basic achievements.On the basis of summarizing the development of space life science in China,this paper mainly introduces the important progress of payload technology and life science research.展开更多
Gordon Life Science Institute is the first Internet Research Institute ever established in the world. It is a non-profit institute. Those scientists who really dedicate themselves to science and loving science more th...Gordon Life Science Institute is the first Internet Research Institute ever established in the world. It is a non-profit institute. Those scientists who really dedicate themselves to science and loving science more than anything else can become its member. In the friendly door-opened Institute, they can maximize their time and energy to engage in their scientific creativity. They have also believed that science would be more truthful and wonderful if scientists do not have to spend a lot of time on funding application, and that great scientific findings and creations in history were often made by those who were least supported or funded but driven by interesting imagination and curiosity. Recollected in this review article is its establishing and developing processes, as well as its philosophy and accomplishments. Particularly, its productive and by-productive outcomes have covered the following five very hot topics in bioinformatics and drug development: 1) PseAAC and PseKNC;2) Disported key theory;3) Wenxiang diagram;4) Multi-label system prediction;5) 5-steps rule. Their impacts on the proteomics and genomics as well as drug development are substantially and awesome.展开更多
The impacts of coronavirus to our planet <span>are</span><span "=""><span> unprecedented;</span><i><span>i.e.</span></i><span>, </span>&...The impacts of coronavirus to our planet <span>are</span><span "=""><span> unprecedented;</span><i><span>i.e.</span></i><span>, </span></span><span>they are</span><span> going to eliminate the entire mankind. Driven by such horrible situation, some philosophical viewpoints have naturally happened. Whether the “World End” must come? If yes, when? During this waiting period, the best way to do science is via the Internet Institute, such as “Gordon Life Science Institute”, and the results thus achieved will be most rewarding.</span>展开更多
Established in 2004, Gordon Life Science Institute is the first Internet Research Institute in the world. It is a non-profit institute, a gift to science. Those scientists, who are really loving science more than anyt...Established in 2004, Gordon Life Science Institute is the first Internet Research Institute in the world. It is a non-profit institute, a gift to science. Those scientists, who are really loving science more than anything else and have shown fantastic creativity in science, can become the membership of such Institute. Their driving force is not funding but firmly belief that scientists will do much better science if they do not have to spend a lot of time for funding application, and that great scientific findings in history were often discovered by those who were without funding at all but driven by profound imagination and curiosity. Summarized in this review are also the accomplishments of the Gordon Life Science Institute and its future perspective.展开更多
With the human space exploration activities,space life science is an emerging interdisciplinary and it covers a wide range of research.Based on our country's manned space station and recoverable satellite science ...With the human space exploration activities,space life science is an emerging interdisciplinary and it covers a wide range of research.Based on our country's manned space station and recoverable satellite science experimental platform,the development of space life science research is very important to acquire new knowledge or new innovation in technology,to give further services to the human space exploration activities,to improve the national economic and social development.Based on present situation,both theoretical and applied researches were continuously performed in2015.Here,we review and summarize the researches on space life sciences which were contributed by Chinese scientists.展开更多
In the past two years, space life science research in China is characterized by a wide area of basic researches for providing foundation for the future China Space Station. The effect of microgravity and radiation was...In the past two years, space life science research in China is characterized by a wide area of basic researches for providing foundation for the future China Space Station. The effect of microgravity and radiation was further studied from physiology phenomena to the level of bio-molecule mechanisms. Chinese space life science is maturing in a new era of comprehensive development.Here, we review and summarize researches on space life sciences which were contributed by Chinese scientists.展开更多
In this review paper, the remarkable impacts of the first Internet Institute, the Gordon Life Science Institute, as well as its profound and far-reaching influence have been systematically and comprehensively presented.
With the human space exploration activities, space life science is an emerging interdiscipline,which covers a wide range of researches. Based on our country's manned space station and recoverable satellite science...With the human space exploration activities, space life science is an emerging interdiscipline,which covers a wide range of researches. Based on our country's manned space station and recoverable satellite science experimental platform, the development of space life science research is very important to acquire new knowledge or new technological innovation, to give further services to the human space exploration activities,to improve the national economic and social development. Both ground-based and flight applied studies were continuously performed in the previous 2 years. Here, we review and summarize the researches on space life sciences contributed by Chinese scientists.展开更多
The College of Life Sciences (CLS) remains one of the most prestigious—and the oldest—colleges in Zhejiang University. This special issue, which includes 16 reviews contributed by our alumni and faculties, is dedica...The College of Life Sciences (CLS) remains one of the most prestigious—and the oldest—colleges in Zhejiang University. This special issue, which includes 16 reviews contributed by our alumni and faculties, is dedicated to mark the 90th Anniversary of CLS.展开更多
Raman imaging,as a molecular spectroscopy technique,has been widely studied and applied in research fields such as life sciences and food safety due to its excellent specificity and high resolution.However,its develop...Raman imaging,as a molecular spectroscopy technique,has been widely studied and applied in research fields such as life sciences and food safety due to its excellent specificity and high resolution.However,its development still faces challenges such as weak signals,slow acquisition speed,and insufficient penetration depth.In recent years,the rapid development of aggregate science has provided new insights for addressing these limitations.Aggregation-induced emission(AIE)materials exhibit enhanced signals in the aggregated state,which may compensate for the inherent weak Raman signals.This article reviews the cutting-edge progress of Raman imaging technology and its current status in cross-disciplinary research with aggregate science,emphasizing the strategy of constructing AIE-Raman dual-responsive probes through molecular engineering to achieve functional complementarity between fluorescence localization and Raman quantification,thereby significantly improving detection sensitivity and specificity.These probes have demonstrated single-cell resolution and high spatiotemporal accuracy in applications such as tumor surgical navigation,diagnosis and treatment of drug-resistant bacteria,and dynamic monitoring of organelles.We also analyze the bottlenecks in this field,such as biological safety and the complexity of molecular design,and outline the future development directions,including intelligent responsive probes,artificial intelligence-assisted analysis,and multimodal fusion platforms.The integration of Raman imaging and AIE sheds new light in the field of medical imaging.展开更多
Healthy life expectancy is a pivotal measure of population health by integrating both life expectancy and the quality of years lived.A significant increase in life expectancy was evident in most populations during the...Healthy life expectancy is a pivotal measure of population health by integrating both life expectancy and the quality of years lived.A significant increase in life expectancy was evident in most populations during the past decades worldwide[1],but the growth in healthy life expectancy has generally lagged behind[2].China has made substantial strides in enhancing both life expectancy and healthy life expectancy.展开更多
Myostatin(MSTN)is principally expressed in skeletal muscle and negatively regulates muscle growth and development.MSTN mutation can induce muscle overgrowth in cattle by activating cell proliferation,presenting a“dou...Myostatin(MSTN)is principally expressed in skeletal muscle and negatively regulates muscle growth and development.MSTN mutation can induce muscle overgrowth in cattle by activating cell proliferation,presenting a“double-muscle”phenotype.However,the specific regulatory mechanism is still unclear.Here,we found that Ca^(2+)content in muscle tissue and muscle satellite cells of MSTN mutated(MSTN^(–/–))cattle were significantly increased compared to wild-type(WT).Furthermore,transcriptome analysis of muscle satellite cells revealed that TRPC4 was significantly increased in MSTN^(–/–)cattle.And the expression of TRPC4 in muscle tissue of MSTN^(–/–)cattle was detected by RT-qPCR and Western blot,which was significantly higher than that of WT.These results suggested that MSTN mutation promoted muscle satellite cells proliferation through activation of TRPC4 channel.To further verify,ML204,a specific inhibitor of TRPC4,was used to treat MSTN^(–/–)muscle satellite cells.We found that cell proliferation was inhibited,calcineurin expression was downregulated,and the entry of NFATc3 into nuclei was reduced,which was similar to WT group.Thus,MSTN mutation leads to the activation of TRPC4 channel,which increases intracellular Ca^(2+)content,further activates calcineurin/NFATc3 pathway,and ultimately promotes the proliferation of muscle satellite cells.展开更多
Banana(Musa spp.)is one of the most important fruit crop worldwide,and plays a critical role in human diet and agricultural economies across tropical and subtropical regions,including China(Jiang et al.,2025;Wu et al....Banana(Musa spp.)is one of the most important fruit crop worldwide,and plays a critical role in human diet and agricultural economies across tropical and subtropical regions,including China(Jiang et al.,2025;Wu et al.,2025).However,its rapid softening severely limits shelf life,causing substantial economic losses during transport and storage.Recently,the enhanced shelf-life can be generated by compromising the key ripening regulators,such as RIN,but other fruit quality traits including flavor and color also can be impaired concurrently(Kitagawa et al.,2005).展开更多
Trentepohliales is a completely terrestrial order within Ulvophyceae(the core Chlorophyta),and its closely related lineages are mainly marine macroalgae(green seaweeds).Despite the considerable interest in their biote...Trentepohliales is a completely terrestrial order within Ulvophyceae(the core Chlorophyta),and its closely related lineages are mainly marine macroalgae(green seaweeds).Despite the considerable interest in their biotechnological potential,little is known about their adaptations to challenging terrestrial habitats.Here,we assemble the high-quality reference genome of Trentepohlia odorata.This alga shows duplications of key genes associated with lipid metabolism and carotenoid synthesis,potentially facilitating intracellular accumulation of lipid droplets and carotenoids.We further reveal positive selection and expansion of gene families involved in vesicle trafficking and cell division regulation in T.odorata compared with other algae(cleavage furrow-mediated cell division)in Ulvophyceae,providing a genetic foundation for the evolution of phragmoplast-mediated cell division.The combined C_(4)-like and biophysical CO_(2)-concentrating mechanisms(CCMs)of T.odorata enable adaptation to fluctuating CO_(2) environments,and support efficient photosynthesis under CO_(2)-limited conditions.Adaptive strategies of T.odorata to terrestrial stressors,such as drought,intense light,and UV-B radiation,include horizontally acquired genes involved in cell wall synthesis and remodeling,homeostasis of aldehydes,and expanded genes associated with reactive oxygen species(ROS),DNA repair,and photoprotection.Our study provides a valuable genomic resource for studying aerial algae and improves understanding of plant terrestrialization.展开更多
Recovering LiFePO_(4) extraction slag(LES)-the FePO_(4)-rich residue formed after Li leaching from spent LiFePO_(4)-has become pivotal to minimizing resource losses,mitigating environmental risks,and advancing circula...Recovering LiFePO_(4) extraction slag(LES)-the FePO_(4)-rich residue formed after Li leaching from spent LiFePO_(4)-has become pivotal to minimizing resource losses,mitigating environmental risks,and advancing circularity in lithium-ion battery value chains.However,integrative frameworks that link closed-loop routes(returning to battery precursors/cathodes)with non-closed-loop upcycling are still limited,constraining process optimization and scale-up.This review synthesizes current progress in LES recycling with emphasis on maximizing recovery efficiency and product value.In closed-loop pathways,hydrometallurgical purification removes impurities to yield battery-grade FePO_(4) as an LiFePO_(4) precursor,while direct relithiation(e.g.,solid-state sintering aided by Li sources and reductants)restores Li and reduces Fe^(3+)to Fe^(2+),thereby regenerating LiFePO_(4) cathodes from LES.In non-closed-loop pathways,compositionally guided upcycling converts LES into advanced materials(e.g.,high-performance electrodes,highcapacity adsorbents),thereby broadening the techno-economic value propositions.We also distill lessons from early industrial practice,identifying constraints arising from feedstock variability,energy-cost coupling(thermal/chemical utilities),and product-quality assurance(battery-grade specifications).Finally,we map research directions-including data-driven feed characterization and process control,defecthealing relithiation strategies and interfacial engineering,quality grading and market pathways,and multi-scenario deployment-to enhance the technical and economic sustainability of LES recycling and accelerate its contribution to a circular battery economy.展开更多
Estimation of the sample position is essential for working process monitoring and management in the life science automation laboratory.Bluetooth low-energy(BLE)beacons have the advantages of low price,small size and l...Estimation of the sample position is essential for working process monitoring and management in the life science automation laboratory.Bluetooth low-energy(BLE)beacons have the advantages of low price,small size and low energy consumption,which make them a promising solution for sample position estimation in the automated laboratory.Several fingerprinting models have been proposed to achieve indoor localization with the received signal strength(RSS)data.However,most of the research depends on intensive beacon installation.Proximity estimation,which depends entirely on one beacon,is more suitable for sample position estimation in large automated laboratories.The complexity of the life science automation laboratory environment brings challenges to the traditional path loss model(PLM),which is a widely used radio wave propagation model-based proximity estimation method.In this paper,BLE sensing devices for sample position estimation are proposed.The BLE beacon-based proximity estimation is discussed in the framework of machine learning,in which the support vector regression(SVR)is utilized to model the nonlinear relationship between the RSS data and distance,and the Kalman filter is utilized to decrease the RSS data deviation.The experimental results over different environments indicate that the SVR outperforms the PLM significantly,and provides 1 m absolute errors for more than 95%of the testing samples.The Kalman filter brings benefits to stable distance predictions.Apart from proximity-based sample position estimation,the proposed framework turned out to be effective in position estimation between parallel workbenches and position estimation on an automated workstation.展开更多
Since the launch in 1950,Science China Series and Science Bulletin have published numerous significant scientific achievements,witnessing the development of science and technology in China and serving as a bridge conn...Since the launch in 1950,Science China Series and Science Bulletin have published numerous significant scientific achievements,witnessing the development of science and technology in China and serving as a bridge connecting Chinese scientists with their counterparts in the international scientific community.展开更多
基金Research Project of Higher Education and Teaching Reform in Heilongjiang Province(SJGY20190484)Heilongjiang Educational Science 13 th Five-Year Plan Project(GBC1317101)Graduate Education and Teaching Reform Project of Heilongjiang Bayi Agricultural University(YJG201803).
文摘Taking the academic association of the Federation of Life Science Research and Innovation of the College of Life Science and Biotechnology of Heilongjiang Bayi Agricultural University as the research platform,it is necessary to organically combine personalized education with the cultivation of innovative and entrepreneurial ability.On the basis of unified teaching ideas,we should pay attention to the individual differences of educational objects,eliminate the disadvantages of traditional education,and break the conventional"spoon-feeding"teaching mode.It is necessary to shift from only paying attention to one-way indoctrination to paying attention to the cultivation of students'innovative quality,and to enhance students'interest in scientific research and practical ability of innovation and entrepreneurship through the rich scientific research activities of academic associations.
文摘With the further advancement of China’s major manned spaceflight project,the national space laboratory was successfully built.China has also made considerable progress and breakthroughs in the field of space life sciences.This paper reviews the related biological effects under space flight conditions,mainly including epigenetic effects,skeleton remodeling and peripheral body fluid circulation effects,as well as the research and application of space life science related biotechnology in the field of microbial culture and biological regeneration life support system.
基金Supported by Space Medical Experiment Project of China Manned Space Program(HYZHXM02003)。
文摘In the past two years,China’s space life science has made great progress.Space biomedical and life science programs have carried out ground-based research for the first batch of projects,and are preparing to carry out space-based experiments along with the construction of China’s space station.And space life science payload of the space station completed the development of positive samples.Thus,with the development of lunar exploration and Mars exploration projects,astrobiology research has also made a lot of basic achievements.On the basis of summarizing the development of space life science in China,this paper mainly introduces the important progress of payload technology and life science research.
文摘Gordon Life Science Institute is the first Internet Research Institute ever established in the world. It is a non-profit institute. Those scientists who really dedicate themselves to science and loving science more than anything else can become its member. In the friendly door-opened Institute, they can maximize their time and energy to engage in their scientific creativity. They have also believed that science would be more truthful and wonderful if scientists do not have to spend a lot of time on funding application, and that great scientific findings and creations in history were often made by those who were least supported or funded but driven by interesting imagination and curiosity. Recollected in this review article is its establishing and developing processes, as well as its philosophy and accomplishments. Particularly, its productive and by-productive outcomes have covered the following five very hot topics in bioinformatics and drug development: 1) PseAAC and PseKNC;2) Disported key theory;3) Wenxiang diagram;4) Multi-label system prediction;5) 5-steps rule. Their impacts on the proteomics and genomics as well as drug development are substantially and awesome.
文摘The impacts of coronavirus to our planet <span>are</span><span "=""><span> unprecedented;</span><i><span>i.e.</span></i><span>, </span></span><span>they are</span><span> going to eliminate the entire mankind. Driven by such horrible situation, some philosophical viewpoints have naturally happened. Whether the “World End” must come? If yes, when? During this waiting period, the best way to do science is via the Internet Institute, such as “Gordon Life Science Institute”, and the results thus achieved will be most rewarding.</span>
文摘Established in 2004, Gordon Life Science Institute is the first Internet Research Institute in the world. It is a non-profit institute, a gift to science. Those scientists, who are really loving science more than anything else and have shown fantastic creativity in science, can become the membership of such Institute. Their driving force is not funding but firmly belief that scientists will do much better science if they do not have to spend a lot of time for funding application, and that great scientific findings in history were often discovered by those who were without funding at all but driven by profound imagination and curiosity. Summarized in this review are also the accomplishments of the Gordon Life Science Institute and its future perspective.
文摘With the human space exploration activities,space life science is an emerging interdisciplinary and it covers a wide range of research.Based on our country's manned space station and recoverable satellite science experimental platform,the development of space life science research is very important to acquire new knowledge or new innovation in technology,to give further services to the human space exploration activities,to improve the national economic and social development.Based on present situation,both theoretical and applied researches were continuously performed in2015.Here,we review and summarize the researches on space life sciences which were contributed by Chinese scientists.
文摘In the past two years, space life science research in China is characterized by a wide area of basic researches for providing foundation for the future China Space Station. The effect of microgravity and radiation was further studied from physiology phenomena to the level of bio-molecule mechanisms. Chinese space life science is maturing in a new era of comprehensive development.Here, we review and summarize researches on space life sciences which were contributed by Chinese scientists.
文摘In this review paper, the remarkable impacts of the first Internet Institute, the Gordon Life Science Institute, as well as its profound and far-reaching influence have been systematically and comprehensively presented.
文摘With the human space exploration activities, space life science is an emerging interdiscipline,which covers a wide range of researches. Based on our country's manned space station and recoverable satellite science experimental platform, the development of space life science research is very important to acquire new knowledge or new technological innovation, to give further services to the human space exploration activities,to improve the national economic and social development. Both ground-based and flight applied studies were continuously performed in the previous 2 years. Here, we review and summarize the researches on space life sciences contributed by Chinese scientists.
文摘The College of Life Sciences (CLS) remains one of the most prestigious—and the oldest—colleges in Zhejiang University. This special issue, which includes 16 reviews contributed by our alumni and faculties, is dedicated to mark the 90th Anniversary of CLS.
文摘Raman imaging,as a molecular spectroscopy technique,has been widely studied and applied in research fields such as life sciences and food safety due to its excellent specificity and high resolution.However,its development still faces challenges such as weak signals,slow acquisition speed,and insufficient penetration depth.In recent years,the rapid development of aggregate science has provided new insights for addressing these limitations.Aggregation-induced emission(AIE)materials exhibit enhanced signals in the aggregated state,which may compensate for the inherent weak Raman signals.This article reviews the cutting-edge progress of Raman imaging technology and its current status in cross-disciplinary research with aggregate science,emphasizing the strategy of constructing AIE-Raman dual-responsive probes through molecular engineering to achieve functional complementarity between fluorescence localization and Raman quantification,thereby significantly improving detection sensitivity and specificity.These probes have demonstrated single-cell resolution and high spatiotemporal accuracy in applications such as tumor surgical navigation,diagnosis and treatment of drug-resistant bacteria,and dynamic monitoring of organelles.We also analyze the bottlenecks in this field,such as biological safety and the complexity of molecular design,and outline the future development directions,including intelligent responsive probes,artificial intelligence-assisted analysis,and multimodal fusion platforms.The integration of Raman imaging and AIE sheds new light in the field of medical imaging.
文摘Healthy life expectancy is a pivotal measure of population health by integrating both life expectancy and the quality of years lived.A significant increase in life expectancy was evident in most populations during the past decades worldwide[1],but the growth in healthy life expectancy has generally lagged behind[2].China has made substantial strides in enhancing both life expectancy and healthy life expectancy.
基金supported by the National Natural Science Foundation of China(32360837 and 32341052)the STI2030 Major Projects,China(2023ZW0404803)+8 种基金the Inner Mongolia Open Competition Projects,China(2022JBGS0025)the Inner Mongolia Science and Technology Leading Team,China(2022LJRC0006)the Inner Mongolia Science and Technology Major Projects,China(2021ZD0009,2021ZD0008,2022ZD0008,2023KJHZ0028)the Inner Mongolia Young Talents Projects,China(NJYT23138)the Inner Mongolia Natural Science Foundation,China(2023MS03004)the Central Government Guides Development,China(2022ZY0212)the National Agricultural Science and Technology Project of China(NK2022130203)the Collaborative Innovation among Universities in Hohhot,China(XTCX2023-06)the Ministry of Education Engineering Centre Project,China(JYBGCSYS2022)。
文摘Myostatin(MSTN)is principally expressed in skeletal muscle and negatively regulates muscle growth and development.MSTN mutation can induce muscle overgrowth in cattle by activating cell proliferation,presenting a“double-muscle”phenotype.However,the specific regulatory mechanism is still unclear.Here,we found that Ca^(2+)content in muscle tissue and muscle satellite cells of MSTN mutated(MSTN^(–/–))cattle were significantly increased compared to wild-type(WT).Furthermore,transcriptome analysis of muscle satellite cells revealed that TRPC4 was significantly increased in MSTN^(–/–)cattle.And the expression of TRPC4 in muscle tissue of MSTN^(–/–)cattle was detected by RT-qPCR and Western blot,which was significantly higher than that of WT.These results suggested that MSTN mutation promoted muscle satellite cells proliferation through activation of TRPC4 channel.To further verify,ML204,a specific inhibitor of TRPC4,was used to treat MSTN^(–/–)muscle satellite cells.We found that cell proliferation was inhibited,calcineurin expression was downregulated,and the entry of NFATc3 into nuclei was reduced,which was similar to WT group.Thus,MSTN mutation leads to the activation of TRPC4 channel,which increases intracellular Ca^(2+)content,further activates calcineurin/NFATc3 pathway,and ultimately promotes the proliferation of muscle satellite cells.
基金supported by the Natural Science Foundation of China(Grant Nos.32172544,32441071)the special fund for scientific innovation strategy-construction of high level Academy of Agriculture Science(Grant No.R2023PY-JG003)+4 种基金the earmarked fund for CARS(Grant No.CARS-31-01)Guangdong Special Support Program(Grant No.NYLJ2024010)Guangdong S&T Program(Grant No.2025B0202070005)IAEA CRP D23033the Project from Guangzhou Municipal Science and Technology Bureau(2023B03J0991).
文摘Banana(Musa spp.)is one of the most important fruit crop worldwide,and plays a critical role in human diet and agricultural economies across tropical and subtropical regions,including China(Jiang et al.,2025;Wu et al.,2025).However,its rapid softening severely limits shelf life,causing substantial economic losses during transport and storage.Recently,the enhanced shelf-life can be generated by compromising the key ripening regulators,such as RIN,but other fruit quality traits including flavor and color also can be impaired concurrently(Kitagawa et al.,2005).
基金supported by the National Natural Science Foundation of China(W2511024,32370228,32470232)the Natural Science Foundation of Jiangsu Province(BK20250004)+3 种基金the Collaborative Innovation Center for Modern Crop Production co-sponsored by Province and Ministry,the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)the fund of Taxonomy Scientist Program'of the Chinese Academy of Sciences(CAS-TAX-24-038)the Youth Innovation Promotion Association CAS(2023355)Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX24_1846).
文摘Trentepohliales is a completely terrestrial order within Ulvophyceae(the core Chlorophyta),and its closely related lineages are mainly marine macroalgae(green seaweeds).Despite the considerable interest in their biotechnological potential,little is known about their adaptations to challenging terrestrial habitats.Here,we assemble the high-quality reference genome of Trentepohlia odorata.This alga shows duplications of key genes associated with lipid metabolism and carotenoid synthesis,potentially facilitating intracellular accumulation of lipid droplets and carotenoids.We further reveal positive selection and expansion of gene families involved in vesicle trafficking and cell division regulation in T.odorata compared with other algae(cleavage furrow-mediated cell division)in Ulvophyceae,providing a genetic foundation for the evolution of phragmoplast-mediated cell division.The combined C_(4)-like and biophysical CO_(2)-concentrating mechanisms(CCMs)of T.odorata enable adaptation to fluctuating CO_(2) environments,and support efficient photosynthesis under CO_(2)-limited conditions.Adaptive strategies of T.odorata to terrestrial stressors,such as drought,intense light,and UV-B radiation,include horizontally acquired genes involved in cell wall synthesis and remodeling,homeostasis of aldehydes,and expanded genes associated with reactive oxygen species(ROS),DNA repair,and photoprotection.Our study provides a valuable genomic resource for studying aerial algae and improves understanding of plant terrestrialization.
基金financially supported by the National Key Research and Development Program of China(Nos.2023YFC3904800)the National Outstanding Young Scientists Fund(No.52125002)+6 种基金the National Science Foundation of China(No.22476073 and U24A20194)the Key Project of Jiangxi Provincial Research and Development Program(Nos.20223BBG74006and 20243BBI91001)the Jiangsu Special Fund on Technology Innovation of Carbon Dioxide Peaking and Carbon Neutrality(No.BT2024011)the China Postdoctoral Science Foundation(Nos.2024M751282 and 2025T180353)the“Thousand Talents Program”of Jiangxi Province(S2021GDQN2161)the Key Project of Ganzhou City Research and Development Program(No.2023PGX17350)the Key Laboratory of Jiangxi Province for Functional Biology and Pollution Control in Red Soil Regions(No.2023SSY02051)。
文摘Recovering LiFePO_(4) extraction slag(LES)-the FePO_(4)-rich residue formed after Li leaching from spent LiFePO_(4)-has become pivotal to minimizing resource losses,mitigating environmental risks,and advancing circularity in lithium-ion battery value chains.However,integrative frameworks that link closed-loop routes(returning to battery precursors/cathodes)with non-closed-loop upcycling are still limited,constraining process optimization and scale-up.This review synthesizes current progress in LES recycling with emphasis on maximizing recovery efficiency and product value.In closed-loop pathways,hydrometallurgical purification removes impurities to yield battery-grade FePO_(4) as an LiFePO_(4) precursor,while direct relithiation(e.g.,solid-state sintering aided by Li sources and reductants)restores Li and reduces Fe^(3+)to Fe^(2+),thereby regenerating LiFePO_(4) cathodes from LES.In non-closed-loop pathways,compositionally guided upcycling converts LES into advanced materials(e.g.,high-performance electrodes,highcapacity adsorbents),thereby broadening the techno-economic value propositions.We also distill lessons from early industrial practice,identifying constraints arising from feedstock variability,energy-cost coupling(thermal/chemical utilities),and product-quality assurance(battery-grade specifications).Finally,we map research directions-including data-driven feed characterization and process control,defecthealing relithiation strategies and interfacial engineering,quality grading and market pathways,and multi-scenario deployment-to enhance the technical and economic sustainability of LES recycling and accelerate its contribution to a circular battery economy.
基金the Synergy Project ADAM(Autonomous Discovery of Advanced Materials)funded by the European Research Council(Grant No.856405).
文摘Estimation of the sample position is essential for working process monitoring and management in the life science automation laboratory.Bluetooth low-energy(BLE)beacons have the advantages of low price,small size and low energy consumption,which make them a promising solution for sample position estimation in the automated laboratory.Several fingerprinting models have been proposed to achieve indoor localization with the received signal strength(RSS)data.However,most of the research depends on intensive beacon installation.Proximity estimation,which depends entirely on one beacon,is more suitable for sample position estimation in large automated laboratories.The complexity of the life science automation laboratory environment brings challenges to the traditional path loss model(PLM),which is a widely used radio wave propagation model-based proximity estimation method.In this paper,BLE sensing devices for sample position estimation are proposed.The BLE beacon-based proximity estimation is discussed in the framework of machine learning,in which the support vector regression(SVR)is utilized to model the nonlinear relationship between the RSS data and distance,and the Kalman filter is utilized to decrease the RSS data deviation.The experimental results over different environments indicate that the SVR outperforms the PLM significantly,and provides 1 m absolute errors for more than 95%of the testing samples.The Kalman filter brings benefits to stable distance predictions.Apart from proximity-based sample position estimation,the proposed framework turned out to be effective in position estimation between parallel workbenches and position estimation on an automated workstation.
文摘Since the launch in 1950,Science China Series and Science Bulletin have published numerous significant scientific achievements,witnessing the development of science and technology in China and serving as a bridge connecting Chinese scientists with their counterparts in the international scientific community.
