AIM： TO determine the expression of DNA （MMR） proteins, including hMLH1 and hMSH2, in gastric epithelial cells in the patients with or without Helicobacter pylori （H pylori）-infected gastritis. METHODS： Fifty Hp...AIM： TO determine the expression of DNA （MMR） proteins, including hMLH1 and hMSH2, in gastric epithelial cells in the patients with or without Helicobacter pylori （H pylori）-infected gastritis. METHODS： Fifty Hpylori-positive patients and 50 H pylori-negative patients were enrolled in the study. During endoscopy of patients with non-ulcer dyspepsia, two antral and two corpus biopsies were taken for histological examination （Giemsa stain） and for immunohistochemical staining of hMLH1 and hMSH2. RESULTS： The percentage of epithelial cell nuclei that demonstrated positivity for hMLH1 staining was 84.14 ± 7.32% in Hpylori-negative patients, while it was 73.34 ±10.10% in Hpylori-positive patients （P 〈 0.0001）. No significant difference was seen between the two groups regarding the percentage of epithelial cell nuclei that demonstrated positivity for hMSH2 staining （81.16±8.32% in H pylori-negative versus 78.24 ± 8.71% in Hpylori-positive patients; P = 0.09）. CONCLUSION： This study indicates that Hpylori might promote development of gastric carcinoma at least in part through its ability to affect the DNA MMR system展开更多
Trends in today' s steel production show increasing demands for highly-sophisticated steel grades. Therefore,the steel industry will eventually be required to install best performing technologies to meet governmen...Trends in today' s steel production show increasing demands for highly-sophisticated steel grades. Therefore,the steel industry will eventually be required to install best performing technologies to meet governmental specifications designed to significantly reduce environmental emissions.Such efforts are supported by innovative new solutions in the entire steel making process.One process that will need to be addressed is the cleanliness of the steel in the liquid steel phase,especially during the BOF-tapping process. The new converter gate(CG)(Fig.1) best supports the slide gate tapping technology for converters in terms of clean steel,productivity,yield and availability-at reduced costs. The CG gate introduces a unique feature for converter slide gates:The bottom plate can be exchanged while the gate remains mounted on the converter.This new feature allows for an increased utilisation of the refractory parts and a significant reduction of the downtime of the converter.This 'designed efficiency' is achieved with a refractory set consisting of three identical plates-two bottom plates and one slider plate-and a nozzle.A number of other improvements such as automatic cylinder coupling using the Interstop SNAP technology and a two step tensioning system have also been implemented. The new system is designed to meet minimal space requirements and therefore will adapt to most BOF shops.To perform preparation,service and maintenance work the modular CG gate can be dismounted from the converter and simultaneously replaced by a ready-to-use unit.The degree of automation for dismounting and mounting as well as for off-line preparation has been enhanced and reduces manual efforts. This paper provides a solution to the obvious trend towards efficient and controlled production of clean steel,in general,and especially at BOF shops.Moreover,it specifically describes the operational results of this innovative BOF tapping equipment at Salzgitter Flachstahl GmbH,Germany.展开更多
Beijing's strong renminbi policy will likely give China's commodity firms enormous buying powers in 2009. Cheap commodities and high leverage at overseas commodity firms provide further support to China's ...Beijing's strong renminbi policy will likely give China's commodity firms enormous buying powers in 2009. Cheap commodities and high leverage at overseas commodity firms provide further support to China's outward FDI. We forecast USD 150-180bn of resource-focused Chinese FDI overseas in 2009,vs.USD 80-100bn of FDI into China.展开更多
Over the recent past few years, there is a huge innovation in plastic surgery and orthopedic surgery through implantation of new techniques, which enabled a great level of success in hand salvage. Conditions such as t...Over the recent past few years, there is a huge innovation in plastic surgery and orthopedic surgery through implantation of new techniques, which enabled a great level of success in hand salvage. Conditions such as trauma, tumor, sepsis, or vascular disease, may necessitate hand salvage. The most frequent argument among surgeon from different subspecialties (orthopedics, plastics, trauma, and vascular surgery) are characterized by in what way each one can do his own part of the salvage operation, be it bony fixation, revascularization, or soft-tissue coverage, but none of them is sure whether it should be endeavored. What is necessary in such clinical situations is an interdisciplinary team attitude led by individual or groups of clinicians who are conversant not only with their identifiable subspecialized skills but also with those of their coworkers and the consequences accompanying the joined efforts at hand salvage. The perception of orthoplastic surgery is based on such an indication, where the integrated skills and techniques of the orthopedic surgeon and reconstructive microsurgeon are performed in recital to direct efforts concerning hand salvage or choose against it when it is not designated. The current article reviews the roles of orthopedic and plastic surgery and how this team can deal with the existing techniques to improve outcomes in hand salvage surgery.展开更多
Chittagong Port is the principal seaport in Bangladesh that has contributed to the national economy with the opportunity to be a world-class regional port in South Asia.Cooperation among the three national ports Chitt...Chittagong Port is the principal seaport in Bangladesh that has contributed to the national economy with the opportunity to be a world-class regional port in South Asia.Cooperation among the three national ports Chittagong,Mongla and Payra is essential to do maritime logistics business in the region after serving the nation proudly.Here,Chittagong Port Authority(CPA)has the opportunity to help others in the process of port development for increasing efficiency and productivity by providing financial and technical assistance because of its financial and technical capabilities as a pioneer seaport in the port world.This paper examines the role of CPA to bolster and develop the underutilized Mongla Port and newly established Payra Port,where qualitative research methodology is applied to explore the ways,by which CPA can assist,link and integrate with others effectively,especially in developing the port infrastructure and inland transport networks.In addition,the research found the prospectus of Mongla and Payra to supply port services to the neighbors India,Nepal,and Bhutan as well as serve the South-West part of China with the aim of increasing regional connectivity and promoting international trade in those basically landlocked areas and countries of Asia.展开更多
Positive y/y inflation is back,which means rising inflation expectations are back on the radar Industrial growth steams ahead,while increasing project starts suggest the same goes for FAI Policies to remain stimulativ...Positive y/y inflation is back,which means rising inflation expectations are back on the radar Industrial growth steams ahead,while increasing project starts suggest the same goes for FAI Policies to remain stimulative,supporting consumption and wage growth into展开更多
In this review article,we explore the interplay between obstructive sleep apnea(OSA)and type 2 diabetes mellitus(T2DM),highlighting a significant yet often overlooked comorbidity.We delve into the pathophysiological l...In this review article,we explore the interplay between obstructive sleep apnea(OSA)and type 2 diabetes mellitus(T2DM),highlighting a significant yet often overlooked comorbidity.We delve into the pathophysiological links between OSA and diabetes,specifically how OSA exacerbates insulin resistance and disrupts glucose metabolism.The research examines the prevalence of OSA in diabetic patients and its role in worsening diabetes-related complications.Emphasizing the importance of comprehensive management,including weight control and positive airway pressure therapy,the study advocates integrated approaches to improve outcomes for patients with T2DM and OSA.This review underscores the necessity of recognizing and addressing OSA in diabetes care to ensure more effective treatment and better patient outcomes.展开更多
China＇s economy will likely start 2010 with double-digit GDP growth, a booming infrastructure build-out, a tightening labour market, and increasing worries about inflation. However, concerns about the global recovery...China＇s economy will likely start 2010 with double-digit GDP growth, a booming infrastructure build-out, a tightening labour market, and increasing worries about inflation. However, concerns about the global recovery and about what will hap- pen when the stimulus package ends mean policy makers will be hesitant to tighten. We expect growth to moderate during the year as consumer spending grows steadily but investment growth slows.展开更多
Car sales in China are booming,but gasoline consumption seems to be stuck in the slow lane. Chart 1 illustrates this apparent mystery(it shows sales of petroleum and oil products,since we do not have data on retail ga...Car sales in China are booming,but gasoline consumption seems to be stuck in the slow lane. Chart 1 illustrates this apparent mystery(it shows sales of petroleum and oil products,since we do not have data on retail gasoline sales).Sceptics point to this odd turn of events as evidence that cars are being bought en masse by state firms and government展开更多
Is China＇s economy really overheating？ Many of the year-on-year （y/y） numbers now look worrying. Electricity production in December 2009 rose 27% y/y, for instance; Q4 GDP rose by 10.7% y/y, above the 8-10% range ...Is China＇s economy really overheating？ Many of the year-on-year （y/y） numbers now look worrying. Electricity production in December 2009 rose 27% y/y, for instance; Q4 GDP rose by 10.7% y/y, above the 8-10% range which most economists agree is .trend growth. The problem with looking at year-on-year numbers, though, is that be-cause of the problems the economy experienced a year ago, the base effects are huge.展开更多
Wages are up by 10%in nominal terms in Guangdong province,our survey suggests That is roughly 6-8%in real terms,which is not inflationary,in our view Rising wages add to the list of challenges already faced by PRD man...Wages are up by 10%in nominal terms in Guangdong province,our survey suggests That is roughly 6-8%in real terms,which is not inflationary,in our view Rising wages add to the list of challenges already faced by PRD manufacturers Factory workers are the winners,though,further supporting consumption growth Wages are on the rise again in Guangdong,a big exporting province,and across much of the rest of China.In recent months,there展开更多
The number of new project starts is still high,pointing to a huge investment boom in 2010 Cement and steel production numbers are a better gauge of real activity than FAI numbers, but also have issues Both have platea...The number of new project starts is still high,pointing to a huge investment boom in 2010 Cement and steel production numbers are a better gauge of real activity than FAI numbers, but also have issues Both have plateaued recently but are likely to rise more after the mid-February展开更多
Today＇s trade data showed a continued strong recovery for China and the world. Both export and import growth exceeded market expectations, at 45.7% and 44.7% y/y, respectively, in nominal terms. This is positive for ...Today＇s trade data showed a continued strong recovery for China and the world. Both export and import growth exceeded market expectations, at 45.7% and 44.7% y/y, respectively, in nominal terms. This is positive for risk sentiment generally, since it suggests that the global recovery, as well as China＇s, is still on track, and it is bullish for the commodity currencies. Here are four key things to know about the recent data.展开更多
In this review article, various preferences in breast plastic surgery particularly after breast cancer will be discussed in view of the diverse indications for the different construction procedures. The various condit...In this review article, various preferences in breast plastic surgery particularly after breast cancer will be discussed in view of the diverse indications for the different construction procedures. The various conditions that necessitate the need for reconstruction are appraised, the important reconstructive procedures are discussed. The most important indications procedures discussed in this review include;Prophylactic subcutaneous mastectomy, Lumpectomy and Radiation, Modified Mastectomy with Axillary Sampling, Nipple reconstruction, and the contralateral breast. These procedures are discussed in view of plastic surgeon practice and patients acceptability in Saudi Arabia. Data from Saudi Arabia in particular was identified through searches of the EMBASE, and MEDLINE database, using the keywords: Saudi Arabia, breast plastic Surgery, breast reconstruction, autologous breast reconstruction, breast augmentation. Advances in prosthetic technologies and modifications in autologous flap techniques, and the development of novel tissue alternatives have allowed for sustained developments in breast reconstruction results. A variety of attitudes has been accessible for addressing the difficulties that endure after resection of breast cancer in Saudi Arabia. Patients should be educated to accept different process in this context.展开更多
Plane, transverse MHD flow through a porous structure is considered in this work. Solution to the governing equations is obtained using an inverse method in which the streamfunction of the flow is considered linear in...Plane, transverse MHD flow through a porous structure is considered in this work. Solution to the governing equations is obtained using an inverse method in which the streamfunction of the flow is considered linear in one of the space variables. Expressions for flow quantities are obtained for finitely conducting and infinitely conducting fluids.展开更多
SOUTH Africa＇s invitation to the BRICS club back in December 2010- arguably President Jacob Zuma＇s greatest foreign policy success - has by association positioned the country as a ＂leading＂ emerging market economy...SOUTH Africa＇s invitation to the BRICS club back in December 2010- arguably President Jacob Zuma＇s greatest foreign policy success - has by association positioned the country as a ＂leading＂ emerging market economy~ While some still question the inclusion based on economic merit, South Africa has become an active member looking to shape the grouping. South Africa is looking to leverage the advantages of this association with particular focus on collaboration opportunities for Africa＇s development.展开更多
IN December 2012, as corporate South Africa closed down for the holiday season, more than 4,500 members of the ruling African National Congress （ANC） descended on the city of Mangaung to elect their leadership for t...IN December 2012, as corporate South Africa closed down for the holiday season, more than 4,500 members of the ruling African National Congress （ANC） descended on the city of Mangaung to elect their leadership for the next five years, and ultimately determine the future of South Africa＇s development.展开更多
The International Committee of Medical Journal Editors(ICMJE)believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves ...The International Committee of Medical Journal Editors(ICMJE)believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016.展开更多
文摘AIM： TO determine the expression of DNA （MMR） proteins, including hMLH1 and hMSH2, in gastric epithelial cells in the patients with or without Helicobacter pylori （H pylori）-infected gastritis. METHODS： Fifty Hpylori-positive patients and 50 H pylori-negative patients were enrolled in the study. During endoscopy of patients with non-ulcer dyspepsia, two antral and two corpus biopsies were taken for histological examination （Giemsa stain） and for immunohistochemical staining of hMLH1 and hMSH2. RESULTS： The percentage of epithelial cell nuclei that demonstrated positivity for hMLH1 staining was 84.14 ± 7.32% in Hpylori-negative patients, while it was 73.34 ±10.10% in Hpylori-positive patients （P 〈 0.0001）. No significant difference was seen between the two groups regarding the percentage of epithelial cell nuclei that demonstrated positivity for hMSH2 staining （81.16±8.32% in H pylori-negative versus 78.24 ± 8.71% in Hpylori-positive patients; P = 0.09）. CONCLUSION： This study indicates that Hpylori might promote development of gastric carcinoma at least in part through its ability to affect the DNA MMR system
文摘Trends in today' s steel production show increasing demands for highly-sophisticated steel grades. Therefore,the steel industry will eventually be required to install best performing technologies to meet governmental specifications designed to significantly reduce environmental emissions.Such efforts are supported by innovative new solutions in the entire steel making process.One process that will need to be addressed is the cleanliness of the steel in the liquid steel phase,especially during the BOF-tapping process. The new converter gate(CG)(Fig.1) best supports the slide gate tapping technology for converters in terms of clean steel,productivity,yield and availability-at reduced costs. The CG gate introduces a unique feature for converter slide gates:The bottom plate can be exchanged while the gate remains mounted on the converter.This new feature allows for an increased utilisation of the refractory parts and a significant reduction of the downtime of the converter.This 'designed efficiency' is achieved with a refractory set consisting of three identical plates-two bottom plates and one slider plate-and a nozzle.A number of other improvements such as automatic cylinder coupling using the Interstop SNAP technology and a two step tensioning system have also been implemented. The new system is designed to meet minimal space requirements and therefore will adapt to most BOF shops.To perform preparation,service and maintenance work the modular CG gate can be dismounted from the converter and simultaneously replaced by a ready-to-use unit.The degree of automation for dismounting and mounting as well as for off-line preparation has been enhanced and reduces manual efforts. This paper provides a solution to the obvious trend towards efficient and controlled production of clean steel,in general,and especially at BOF shops.Moreover,it specifically describes the operational results of this innovative BOF tapping equipment at Salzgitter Flachstahl GmbH,Germany.
文摘Beijing's strong renminbi policy will likely give China's commodity firms enormous buying powers in 2009. Cheap commodities and high leverage at overseas commodity firms provide further support to China's outward FDI. We forecast USD 150-180bn of resource-focused Chinese FDI overseas in 2009,vs.USD 80-100bn of FDI into China.
文摘Over the recent past few years, there is a huge innovation in plastic surgery and orthopedic surgery through implantation of new techniques, which enabled a great level of success in hand salvage. Conditions such as trauma, tumor, sepsis, or vascular disease, may necessitate hand salvage. The most frequent argument among surgeon from different subspecialties (orthopedics, plastics, trauma, and vascular surgery) are characterized by in what way each one can do his own part of the salvage operation, be it bony fixation, revascularization, or soft-tissue coverage, but none of them is sure whether it should be endeavored. What is necessary in such clinical situations is an interdisciplinary team attitude led by individual or groups of clinicians who are conversant not only with their identifiable subspecialized skills but also with those of their coworkers and the consequences accompanying the joined efforts at hand salvage. The perception of orthoplastic surgery is based on such an indication, where the integrated skills and techniques of the orthopedic surgeon and reconstructive microsurgeon are performed in recital to direct efforts concerning hand salvage or choose against it when it is not designated. The current article reviews the roles of orthopedic and plastic surgery and how this team can deal with the existing techniques to improve outcomes in hand salvage surgery.
文摘Chittagong Port is the principal seaport in Bangladesh that has contributed to the national economy with the opportunity to be a world-class regional port in South Asia.Cooperation among the three national ports Chittagong,Mongla and Payra is essential to do maritime logistics business in the region after serving the nation proudly.Here,Chittagong Port Authority(CPA)has the opportunity to help others in the process of port development for increasing efficiency and productivity by providing financial and technical assistance because of its financial and technical capabilities as a pioneer seaport in the port world.This paper examines the role of CPA to bolster and develop the underutilized Mongla Port and newly established Payra Port,where qualitative research methodology is applied to explore the ways,by which CPA can assist,link and integrate with others effectively,especially in developing the port infrastructure and inland transport networks.In addition,the research found the prospectus of Mongla and Payra to supply port services to the neighbors India,Nepal,and Bhutan as well as serve the South-West part of China with the aim of increasing regional connectivity and promoting international trade in those basically landlocked areas and countries of Asia.
文摘Positive y/y inflation is back,which means rising inflation expectations are back on the radar Industrial growth steams ahead,while increasing project starts suggest the same goes for FAI Policies to remain stimulative,supporting consumption and wage growth into
文摘In this review article,we explore the interplay between obstructive sleep apnea(OSA)and type 2 diabetes mellitus(T2DM),highlighting a significant yet often overlooked comorbidity.We delve into the pathophysiological links between OSA and diabetes,specifically how OSA exacerbates insulin resistance and disrupts glucose metabolism.The research examines the prevalence of OSA in diabetic patients and its role in worsening diabetes-related complications.Emphasizing the importance of comprehensive management,including weight control and positive airway pressure therapy,the study advocates integrated approaches to improve outcomes for patients with T2DM and OSA.This review underscores the necessity of recognizing and addressing OSA in diabetes care to ensure more effective treatment and better patient outcomes.
文摘China＇s economy will likely start 2010 with double-digit GDP growth, a booming infrastructure build-out, a tightening labour market, and increasing worries about inflation. However, concerns about the global recovery and about what will hap- pen when the stimulus package ends mean policy makers will be hesitant to tighten. We expect growth to moderate during the year as consumer spending grows steadily but investment growth slows.
文摘Car sales in China are booming,but gasoline consumption seems to be stuck in the slow lane. Chart 1 illustrates this apparent mystery(it shows sales of petroleum and oil products,since we do not have data on retail gasoline sales).Sceptics point to this odd turn of events as evidence that cars are being bought en masse by state firms and government
文摘Is China＇s economy really overheating？ Many of the year-on-year （y/y） numbers now look worrying. Electricity production in December 2009 rose 27% y/y, for instance; Q4 GDP rose by 10.7% y/y, above the 8-10% range which most economists agree is .trend growth. The problem with looking at year-on-year numbers, though, is that be-cause of the problems the economy experienced a year ago, the base effects are huge.
文摘Wages are up by 10%in nominal terms in Guangdong province,our survey suggests That is roughly 6-8%in real terms,which is not inflationary,in our view Rising wages add to the list of challenges already faced by PRD manufacturers Factory workers are the winners,though,further supporting consumption growth Wages are on the rise again in Guangdong,a big exporting province,and across much of the rest of China.In recent months,there
文摘The number of new project starts is still high,pointing to a huge investment boom in 2010 Cement and steel production numbers are a better gauge of real activity than FAI numbers, but also have issues Both have plateaued recently but are likely to rise more after the mid-February
文摘Today＇s trade data showed a continued strong recovery for China and the world. Both export and import growth exceeded market expectations, at 45.7% and 44.7% y/y, respectively, in nominal terms. This is positive for risk sentiment generally, since it suggests that the global recovery, as well as China＇s, is still on track, and it is bullish for the commodity currencies. Here are four key things to know about the recent data.
文摘In this review article, various preferences in breast plastic surgery particularly after breast cancer will be discussed in view of the diverse indications for the different construction procedures. The various conditions that necessitate the need for reconstruction are appraised, the important reconstructive procedures are discussed. The most important indications procedures discussed in this review include;Prophylactic subcutaneous mastectomy, Lumpectomy and Radiation, Modified Mastectomy with Axillary Sampling, Nipple reconstruction, and the contralateral breast. These procedures are discussed in view of plastic surgeon practice and patients acceptability in Saudi Arabia. Data from Saudi Arabia in particular was identified through searches of the EMBASE, and MEDLINE database, using the keywords: Saudi Arabia, breast plastic Surgery, breast reconstruction, autologous breast reconstruction, breast augmentation. Advances in prosthetic technologies and modifications in autologous flap techniques, and the development of novel tissue alternatives have allowed for sustained developments in breast reconstruction results. A variety of attitudes has been accessible for addressing the difficulties that endure after resection of breast cancer in Saudi Arabia. Patients should be educated to accept different process in this context.
文摘Plane, transverse MHD flow through a porous structure is considered in this work. Solution to the governing equations is obtained using an inverse method in which the streamfunction of the flow is considered linear in one of the space variables. Expressions for flow quantities are obtained for finitely conducting and infinitely conducting fluids.
文摘SOUTH Africa＇s invitation to the BRICS club back in December 2010- arguably President Jacob Zuma＇s greatest foreign policy success - has by association positioned the country as a ＂leading＂ emerging market economy~ While some still question the inclusion based on economic merit, South Africa has become an active member looking to shape the grouping. South Africa is looking to leverage the advantages of this association with particular focus on collaboration opportunities for Africa＇s development.
文摘IN December 2012, as corporate South Africa closed down for the holiday season, more than 4,500 members of the ruling African National Congress （ANC） descended on the city of Mangaung to elect their leadership for the next five years, and ultimately determine the future of South Africa＇s development.
文摘The International Committee of Medical Journal Editors(ICMJE)believes that there is an ethical obligation to responsibly share data generated by interventional clinical trials because participants have put themselves at risk.In a growing consensus,many funders around the world-foundations,government agencies,and industry-now mandate data sharing.Here,we outline ICMJE's proposed requirements to help meet this obligation.We encourage feedback on the proposed requirements.Anyone can provide feedback at www.icmje.org by April 18,2016.
