This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven second...This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven secondary sources,taking as an example ion acceleration by target normal sheath acceleration.The Pearson linear correlation of maximum return current amplitude and proton spectrum cutoff energy is found to be in the range from~0.70 to 0.94.kA-scale return currents rise in all interaction schemes where targets of any kind are charged by escaping laser-accelerated relativistic electrons.Their precise measurement is demonstrated using an inductive scheme that allows operation at high repetition rates.Thus,return currents can be used as a metrological online tool for the optimization of many laser-driven secondary sources and for diagnosing their stability.In particular,in two parametric studies of laser-driven ion acceleration,we carry out a noninvasive online measurement of return currents in a tape target system irradiated by the 1 PW VEGA-3 laser at Centro de Láseres Pulsados:first the size of the irradiated area is varied at best compression of the laser pulse;second,the pulse duration is varied by means of induced group delay dispersion at best focus.This work paves the way to the development of feedback systems that operate at the high repetition rates of PW-class lasers.展开更多
We introduce a scheme aiming at the generation of quasi-monochromatic carbon ion bunches from laser-solid interaction.The proposed scheme is an extension of the“peeler”acceleration originally proposed for proton acc...We introduce a scheme aiming at the generation of quasi-monochromatic carbon ion bunches from laser-solid interaction.The proposed scheme is an extension of the“peeler”acceleration originally proposed for proton acceleration,which involves irradiating the narrow(submicrometer)side of a tape target.This results in the generation of a surface plasma wave and the subsequent acceleration of a proton bunch with high peak energy,quasi-monochromaticity,low energy bandwidth,and low divergence by the electrostatic field induced at the target rear.Up to now,the higher-Z(e.g.,carbon)ion bunches obtained with the peeler scheme have been found to exhibit an exponentially decaying thermal-like energy spectrum.To achieve a low energy bandwidth,we place a mass-limited carbon structure at the rear of the target.Using 3D particle-in-cell simulations,we show that a quasi-monochromatic carbon bunch can indeed be obtained.With a multi-PW laser pulse,10^(8) carbon ions with peak energy~110 MeV/u and with a divergence of 20° in the vertical plane and~1° in the horizontal plane can be generated.The quasi-monochromaticity,together with the low duration of the beam and in combination with the versatility of high-power laser facilities,should make this scheme attractive for practical applications such as heavy ion cancer therapy and higher-resolution diagnostics of extreme plasma states.展开更多
Recent experiments at the National Ignition Facility and theoretical modeling suggest that side stimulated Raman scattering(SSRS)instability could reduce laser–plasma coupling and generate considerable fluxes of supr...Recent experiments at the National Ignition Facility and theoretical modeling suggest that side stimulated Raman scattering(SSRS)instability could reduce laser–plasma coupling and generate considerable fluxes of suprathermal hot electrons under interaction conditions envisaged for direct-drive schemes for inertial confinement fusion.Nonetheless,SSRS remains to date one of the least understood parametric instabilities.Here,we report the first angularly and spectrally resolved measurements of scattered light at laser intensities relevant for the shock ignition scheme(I×10^(16)W/cm^(2)),showing significant SSRS growth in the direction perpendicular to the laser polarization.Modification of the focal spot shape and orientation,obtained by using two different random phase plates,and of the density gradient of the plasma,by utilizing exploding foil targets of different thicknesses,clearly reveals a different dependence of backward SRS(BSRS)and SSRS on experimental parameters.While convective BSRS scales with plasma density scale length,as expected by linear theory,the growth of SSRS depends on the spot extension in the direction perpendicular to laser polarization.Our analysis therefore demonstrates that under current experimental conditions,with density scale lengths L_(n)≈60–120μm and spot sizes FWHM≈40–100μm,SSRS is limited by laser beam size rather than by the density scale length of the plasma.展开更多
Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential a...Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential applications:as an alternative to deuterium-tritium for fusion energy production,astrophysics studies,and alpha-particle generation for medical treatment.One possible scheme for laser-driven p-^(11)B reactions is to direct a beam of laser-accelerated protons onto a boron(B)sample(the so-called“pitcher-catcher”scheme).This technique has been successfully implemented on large high-energy lasers,yielding hundreds of joules per shot at low repetition.We present here a complementary approach,exploiting the high repetition rate of the VEGA III petawatt laser at CLPU(Spain),aiming at accumulating results from many interactions at much lower energy,to provide better control of the parameters and the statistics of the measurements.Despite a moderate energy per pulse,our experiment allowed exploration of the laser-driven fusion process with tens(up to hundreds)of laser shots.The experiment provided a clear signature of the reactions involved and of the fusion products,accumulated over many shots,leading to an improved optimization of the diagnostics for experimental campaigns of this type.In this paper,we discuss the effectiveness of laser-driven p-11B fusion in the pitcher-catcher scheme,at a high repetition rate,addressing the challenges of this experimental scheme and highlighting its critical aspects.Our proposed methodology allows evaluation of the performance of this scheme for laser-driven alpha particle production and can be adapted to high-repetition-rate laser facilities with higher energy and intensity.展开更多
Porous materials offer unique possibilities for the production of plasmas with controlled density profiles for experiments on laser–matter interaction.They are of growing relevance to many applications,such as inerti...Porous materials offer unique possibilities for the production of plasmas with controlled density profiles for experiments on laser–matter interaction.They are of growing relevance to many applications,such as inertial confinement fusion,fundamental research,and secondary sources.Understanding the processes of transformation of a porous solid into a plasma is of fundamental interest and is needed for producing materials with desired properties.展开更多
The thermodynamic properties of boron nitride under extreme pressures and temperatures are of great interest and importance for materials science and inertial confinement fusion physics,but they are poorly understood ...The thermodynamic properties of boron nitride under extreme pressures and temperatures are of great interest and importance for materials science and inertial confinement fusion physics,but they are poorly understood owing to the challenges of performing experiments and realizing ab initio calculations.Here,we report the first shock Hugoniot data on hexagonal boron nitride at pressures of 5–16 Mbar,using hohlraum-driven shock waves at the SGIII-p laser facility in China.Our density functional theory molecular dynamics calculations closely match experimental data,validating the equations of state for modeling the shock response of boron nitride and filling a crucial gap in the knowledge of boron nitride properties in the region of multi-Mbar pressures and eV temperatures.The results presented here provide fundamental insights into boron nitride under the extreme conditions relevant to inertial confinement fusion,hydrogen–boron fusion,and high-energy-density physics.展开更多
We have recently proposed a new technique of plasma tailoring by laser-driven hydrodynamic shockwaves generated on both sides of a gas jet[Marquès et al.,Phys.Plasmas 28,023103(2021)].In a continuation of this nu...We have recently proposed a new technique of plasma tailoring by laser-driven hydrodynamic shockwaves generated on both sides of a gas jet[Marquès et al.,Phys.Plasmas 28,023103(2021)].In a continuation of this numerical work,we study experimentally the influence of the tailoring on proton acceleration driven by a high-intensity picosecond laser in three cases:without tailoring,by tailoring only the entrance side of the picosecond laser,and by tailoring both sides of the gas jet.Without tailoring,the acceleration is transverse to the laser axis,with a low-energy exponential spectrum,produced by Coulomb explosion.When the front side of the gas jet is tailored,a forward acceleration appears,which is significantly enhanced when both the front and back sides of the plasma are tailored.This forward acceleration produces higher-energy protons,with a peaked spectrum,and is in good agreement with the mechanism of collisionless shock acceleration(CSA).The spatiotemporal evolution of the plasma profile is characterized by optical shadowgraphy of a probe beam.The refraction and absorption of this beam are simulated by post-processing 3D hydrodynamic simulations of the plasma tailoring.Comparison with the experimental results allows estimation of the thickness and near-critical density of the plasma slab produced by tailoring both sides of the gas jet.These parameters are in good agreement with those required for CSA.展开更多
The discovery of chirped pulse amplification has led to great improvements in laser technology,enabling energetic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few micrometer...The discovery of chirped pulse amplification has led to great improvements in laser technology,enabling energetic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few micrometers.Protons with energies of tens of MeV can be accelerated using,for instance,target normal sheath acceleration and focused on secondary targets.Under such conditions,nuclear reactions can occur,with the production of radioisotopes suitable for medical application.The use of high-repetition lasers to produce such isotopes is competitive with conventional methods mostly based on accelerators.In this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currently used in positron emission tomography and other applications.At the same time,we study the reactions^(10)B(p,α)^(7)Be and^(70)Zn(p,4n)^(67)Ga to put further constraints on the proton distributions at different angles,as well as the reaction^(11)B(p,α)^(8)Be relevant for energy production.The experiment was performed at the 1 PW laser facility at VegaⅢin Salamanca,Spain.Angular distributions of radioisotopes in the forward(with respect to the laser direction)and backward directions were measured using a high purity germanium detector.Our results are in reasonable agreement with numerical estimates obtained following the approach of Kimura and Bonasera[Nucl.Instrum.Methods Phys.Res.,Sect.A 637,164–170(2011)].展开更多
We report novel results on top-down percussion drilling in different glasses with femtosecond laser GHz-bursts.Thanks to this particular regime of light–matter interaction,combining non-linear absorption and thermal ...We report novel results on top-down percussion drilling in different glasses with femtosecond laser GHz-bursts.Thanks to this particular regime of light–matter interaction,combining non-linear absorption and thermal cumulative effects,we obtained crack-free holes of aspect ratios exceeding 30 in sodalime and 70 in fused silica.The results are discussed in terms of inner wall morphology,aspect ratio and drilling speed.展开更多
AIM: To compare the efficacy and safety of recombinant streptokinase(rSK) vs hydrocortisone acetate-based suppositories in acute hemorrhoidal disease.METHODS: A multicenter(11 sites), randomized(1:1:1), open, controll...AIM: To compare the efficacy and safety of recombinant streptokinase(rSK) vs hydrocortisone acetate-based suppositories in acute hemorrhoidal disease.METHODS: A multicenter(11 sites), randomized(1:1:1), open, controlled trial with parallel groups was performed. All participating patients gave their written,informed consent. After inclusion, patients with acute symptoms of hemorrhoids were centrally randomized to receive, as outpatients, by the rectal route, suppositories of rSK 200000 IU of one unit every 8 h(first 3 units)and afterwards every 12 h until 8 administrations were completed(schedule A), one unit every 8 h until 6 units were completed(schedule B), or 25 mg hydrocortisone acetate once every 8 h up to a maximum of 24 administrations. Evaluations were performed at 3, 5,and 10 d post-inclusion. The main end-point was the 5thday response(disappearance of pain and bleeding, and≥ 70% reduction of the lesion size). Time to response and need for thrombectomy were secondary efficacy variables. Adverse events were also evaluated.RESULTS: Groups were homogeneous with regards to demographic and baseline characteristics. Fifth day complete response rates were 156/170(91.8%; 95%CI:87.3-96.2), 155/170(91.2%; 95%CI: 86.6%-95.7%),and 46/170(27.1%; 95%CI: 20.1%-34.0%) with rSK(schedule A and B) and hydrocortisone acetate suppositories, respectively. These 64.6% and 63.9%differences(95%CI: 56.7%-72.2% and 55.7%-72.0%)were highly significant(P < 0.001). This advantage was detected since the early 3rd day evaluation(68.8% and64.1% vs 7.1% for the rSK and active control groups,respectively; P < 0.001) and was maintained even at the late 10 th day assessment(97.1% and 93.5% vs67.1% for rSK and hydrocortisone acetate, respectively;P < 0.001). Time to response was 3 d(95%CI: 2.9-3.1)for both rSK groups and 10 d(95%CI: 9.3-10.7) in the hydrocortisone acetate group. This difference was highly significant(P < 0.001). All subgroup stratified analyses(with or without thrombosis and hemorrhoid classification) showed a statistically significant advantage for the rSK groups. Thrombectomy was necessary in4/251 and 14/133 patients with baseline thrombosis in the rSK and hydrocortisone acetate groups, respectively(P < 0.001). There were no adverse events attributable to the experimental treatment.CONCLUSION: rSK suppositories showed a significant advantage over a widely-used over-the-counter hydrocortisone acetate preparation for the treatment of acute hemorrhoidal illness, as well as having an adequate safety profile.展开更多
With the much-anticipated multi-petawatt(PW)laser facilities that are coming online,neutron sources with extreme fluxes could soon be in reach.Such sources would rely on spallation by protons accelerated by the high-i...With the much-anticipated multi-petawatt(PW)laser facilities that are coming online,neutron sources with extreme fluxes could soon be in reach.Such sources would rely on spallation by protons accelerated by the high-intensity lasers.These high neutron fluxes would make possible not only direct measurements of neutron capture andβ-decay rates related to the r-process of nucleosynthesis of heavy elements,but also such nuclear measurements in a hot plasma environment,which would be beneficial for s-process investigations in astrophysically relevant conditions.This could,in turn,finally allow possible reconciliation of the observed element abundances in stars and those derived from simulations,which at present show large discrepancies.Here,we review a possible pathway to reach unprecedented neutron fluxes using multi-PW lasers,as well as strategies to perform measurements to investigate the r-and s-processes of nucleosynthesis of heavy elements in cold matter,as well as in a hot plasma environment.展开更多
Direct laser acceleration(DLA)of electrons in a plasma of near-critical electron density(NCD)and the associated synchrotron-like radiation are discussed for moderate relativistic laser intensity(normalized laser ampli...Direct laser acceleration(DLA)of electrons in a plasma of near-critical electron density(NCD)and the associated synchrotron-like radiation are discussed for moderate relativistic laser intensity(normalized laser amplitude a0≤4.3)and ps length pulse.This regime is typical of kJ PW-class laser facilities designed for high-energy-density(HED)research.In experiments at the PHELIX facility,it has been demonstrated that interaction of a 1019 W/cm2 sub-ps laser pulse with a sub-mm length NCD plasma results in the generation of high-current well-directed superponderomotive electrons with an effective temperature ten times higher than the ponderomotive potential[Rosmej et al.,Plasma Phys.Controlled Fusion 62,115024(2020)].Three-dimensional particle-in-cell simulations provide good agreement with the measured electron energy distribution and are used in the current work to study synchrotron radiation from the DLA-accelerated electrons.The resulting x-ray spectrum with a critical energy of 5 keV reveals an ultrahigh photon number of 731011 in the 1–30 keV photon energy range at the focused laser energy of 20 J.Numerical simulations of betatron x-ray phase contrast imaging based on the DLA process for the parameters of a PHELIX laser are presented.The results are of interest for applications in HED experiments,which require a ps x-ray pulse and a high photon flux.展开更多
In an experiment carried out at the Prague Asterix Laser System at laser intensities relevant to shock ignition conditions(I>10^(16) W/cm^(2)),the heating and transport of hot electrons were studied by using severa...In an experiment carried out at the Prague Asterix Laser System at laser intensities relevant to shock ignition conditions(I>10^(16) W/cm^(2)),the heating and transport of hot electrons were studied by using several complementary diagnostics,i.e.,K_(α)time-resolved imaging,hard x-ray filtering(a bremsstrahlung cannon),and electron spectroscopy.Ablators with differing composition from low Z(parylene N)to high Z(nickel)were used in multilayer planar targets to produce plasmas with different coronal temperature and collisionality and modify the conditions of hot-electron generation.The variety of available diagnostics allowed full characterization of the population of hot electrons,retrieving their conversion efficiency,time generation and duration,temperature,and angular divergence.The obtained results are shown to be consistent with those from detailed simulations and similar inertial confinement fusion experiments.Based on the measured data,the advantages,reliability,and complementarity of the experimental diagnostics are discussed.展开更多
We present new diagnostics for use in optical laser pump-X-ray Free Electron Laser(XFEL)probe experiments to monitor dimensions,intensity profile and focusability of the XFEL beam and to control initial quality and ho...We present new diagnostics for use in optical laser pump-X-ray Free Electron Laser(XFEL)probe experiments to monitor dimensions,intensity profile and focusability of the XFEL beam and to control initial quality and homogeneity of targets to be driven by optical laser pulse.By developing X-ray imaging,based on the use of an LiF crystal detector,we were able to measure the distribution of energy inside a hard X-ray beam with unprecedented high spatial resolution(~1 mm)and across a field of view larger than some millimetres.This diagnostic can be used in situ,provides a very high dynamic range,has an extremely limited cost,and is relatively easy to be implemented in pump-probe experiments.The proposed methods were successfully applied in pump-probe experiments at the SPring-8 Angstrom Compact free electron LAser(SACLA)XFEL facility and its potential was demonstrated for current and future High Energy Density Science experiments.展开更多
We present a novel scheme for rapid quantitative analysis of debris generated during experiments with solid targets following relativistic laser–plasma interaction at high-power laser facilities.Results are supported...We present a novel scheme for rapid quantitative analysis of debris generated during experiments with solid targets following relativistic laser–plasma interaction at high-power laser facilities.Results are supported by standard analysis techniques.Experimental data indicate that predictions by available modelling for non-mass-limited targets are reasonable,with debris of the order of hundreds ofμg per shot.We detect for the first time two clearly distinct types of debris emitted from the same interaction.A fraction of the debris is ejected directionally,following the target normal(rear and interaction side).The directional debris ejection towards the interaction side is larger than on the side of the target rear.The second type of debris is characterized by a more spherically uniform ejection,albeit with a small asymmetry that favours ejection towards the target rear side.展开更多
We describe two numerical investigations performed using a 3D plasma Monte-Carlo code,developed to study hot-electron transport in the context of inertial confinement fusion.The code simulates the propagation of hot e...We describe two numerical investigations performed using a 3D plasma Monte-Carlo code,developed to study hot-electron transport in the context of inertial confinement fusion.The code simulates the propagation of hot electrons in ionized targets,using appropriate scattering differential cross sections with free plasma electrons and ionized or partially ionized atoms.In this paper,we show that a target in the plasma state stops and diffuses electrons more effectively than a cold target(i.e.,a target under standard conditions in which ionization is absent).This is related to the fact that in a plasma,the nuclear potential of plasma nuclei has a greater range than in the cold case,where the screening distance is determined by the electronic structure of atoms.However,in the ablation zone created by laser interaction,electrons undergo less severe scattering,counterbalancing the enhanced diffusion that occurs in the bulk.We also show that hard collisions,i.e.,collisions with large polar scattering angle,play a primary role in electron beam diffusion and should not be neglected.An application of the plasma MonteCarlo model to typical shock ignition implosions suggests that hot electrons will not give rise to any preheating concerns if their Maxwellian temperature is lower than 25–30 keV,although the presence of populations at higher temperatures must be suppressed.This result does not depend strongly on the initial angular divergence of the electron beam set in the simulations.展开更多
We describe the development of a 3D Monte-Carlo model to study hot-electron transport in ionized or partially ionized targets,considering regimes typical of inertial confinement fusion.Electron collisions are modeled ...We describe the development of a 3D Monte-Carlo model to study hot-electron transport in ionized or partially ionized targets,considering regimes typical of inertial confinement fusion.Electron collisions are modeled using a mixed simulation algorithm that considers both soft and hard scattering phenomena.Soft collisions are modeled according to multiple-scattering theories,i.e.,considering the global effects of the scattering centers on the primary particle.Hard collisions are simulated by considering a two-body interaction between an electron and a plasma particle.Appropriate differential cross sections are adopted to correctly model scattering in ionized or partially ionized targets.In particular,an analytical form of the differential cross section that describes a collision between an electron and the nucleus of a partially ionized atom in a plasma is proposed.The loss of energy is treated according to the continuous slowing down approximation in a plasma stopping power theory.Validation against Geant4 is presented.The code will be implemented as a module in 3D hydrodynamic codes,providing a basis for the development of robust shock ignition schemes and allowing more precise interpretations of current experiments in planar or spherical geometries.展开更多
An analytical model of current propagation in a helical coil with varying geometry is developed.It can be used for post-acceleration and post-focusing of ions produced via laser-driven target normal sheath acceleratio...An analytical model of current propagation in a helical coil with varying geometry is developed.It can be used for post-acceleration and post-focusing of ions produced via laser-driven target normal sheath acceleration and generation of electromagnetic pulses.We calculate the current that propagates in a helical coil and suggest a method for improving its dispersion properties using a screening tube and with pitch and radius variation.The electromagnetic fields calculated with the analytical model are in agreement with particle-in-cell simulations.The model provides insights into the physics of current propagation in helical coils with varying geometries and enables a numerical implementation for rapid proton spectrum computations,which facilitate the design of such coils for future experiments.展开更多
基金funding from the European Union’s Horizon 2020 research and innovation program through the European IMPULSE project under Grant Agreement No.871161from LASERLAB-EUROPE V under Grant Agreement No.871124+6 种基金from the Grant Agency of the Czech Republic(Grant No.GM23-05027M)Grant No.PDC2021120933-I00 funded by MCIN/AEI/10.13039/501100011033by the European Union Next Generation EU/PRTRsupported by funding from the Ministerio de Ciencia,Innovación y Universidades in Spain through ICTS Equipment Grant No.EQC2018-005230-Pfrom Grant No.PID2021-125389O A-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER,UEby“ERDF A Way of Making Europe”by the European Unionfrom grants of the Junta de Castilla y León with Grant Nos.CLP263P20 and CLP087U16。
文摘This work demonstrates experimentally the close relation between return currents from relativistic laser-driven target polarization and the quality of the relativistic laser–plasma interaction for laser-driven secondary sources,taking as an example ion acceleration by target normal sheath acceleration.The Pearson linear correlation of maximum return current amplitude and proton spectrum cutoff energy is found to be in the range from~0.70 to 0.94.kA-scale return currents rise in all interaction schemes where targets of any kind are charged by escaping laser-accelerated relativistic electrons.Their precise measurement is demonstrated using an inductive scheme that allows operation at high repetition rates.Thus,return currents can be used as a metrological online tool for the optimization of many laser-driven secondary sources and for diagnosing their stability.In particular,in two parametric studies of laser-driven ion acceleration,we carry out a noninvasive online measurement of return currents in a tape target system irradiated by the 1 PW VEGA-3 laser at Centro de Láseres Pulsados:first the size of the irradiated area is varied at best compression of the laser pulse;second,the pulse duration is varied by means of induced group delay dispersion at best focus.This work paves the way to the development of feedback systems that operate at the high repetition rates of PW-class lasers.
基金the support of the Romanian Government and the European Union through the European Regional Development Fund–the Competitiveness Operational Programme (1/07.07.2016, COP, Grant ID No. 1334) Phases Ⅱthe Romanian Ministry of Research, Innovation and Digitalization: Program Nucleu Grant No. PN23210105+6 种基金supported by the IOSIN Funds for Research Infrastructures of National Interest funded by the Romanian Ministry of Research, Innovation and Digitalizationsupported by Project No. ELI-RO/DFG/2023_001 ARNPhot funded by the Institute of Atomic Physics (Romania), the European Union, the Romanian Governmentthe Health Program, within the project “Medical Applications of High-Power Lasers–Dr. LASER,” SMIS Code 326475by Grant Nos. ELI-RO/RDI/2024_14 SPARC and ELI-RO/RDI/2024_8 AMAPBMBF Grant No. 05P24PF2 (Germany)the EuroHPC Joint Undertaking for awarding us access to Karolina at IT4Innovations (VAB-TU), Czechia under Project No. EHPCREG-2023R02-006 (Grant No. DD-23-157)Ministry of Education, Youth and Sports of the Czech Republic through e-INFRA CZ (Grant ID No. 90140)
文摘We introduce a scheme aiming at the generation of quasi-monochromatic carbon ion bunches from laser-solid interaction.The proposed scheme is an extension of the“peeler”acceleration originally proposed for proton acceleration,which involves irradiating the narrow(submicrometer)side of a tape target.This results in the generation of a surface plasma wave and the subsequent acceleration of a proton bunch with high peak energy,quasi-monochromaticity,low energy bandwidth,and low divergence by the electrostatic field induced at the target rear.Up to now,the higher-Z(e.g.,carbon)ion bunches obtained with the peeler scheme have been found to exhibit an exponentially decaying thermal-like energy spectrum.To achieve a low energy bandwidth,we place a mass-limited carbon structure at the rear of the target.Using 3D particle-in-cell simulations,we show that a quasi-monochromatic carbon bunch can indeed be obtained.With a multi-PW laser pulse,10^(8) carbon ions with peak energy~110 MeV/u and with a divergence of 20° in the vertical plane and~1° in the horizontal plane can be generated.The quasi-monochromaticity,together with the low duration of the beam and in combination with the versatility of high-power laser facilities,should make this scheme attractive for practical applications such as heavy ion cancer therapy and higher-resolution diagnostics of extreme plasma states.
基金financial support from the LASERLAB-EUROPE Access to Research Infrastructure Activity (Application No. 23068)carried out within the framework of EUROfusion Enabling Research Projects AWP21-ENR-01-CEA02 and AWP24-ENR-IFE-02-CEA-02+3 种基金received funding from Euratom Research and Training Programme 2021–2025 under Grant No. 633053supported by the Ministry of Youth and Sports of the Czech Republic [Project No. LM2023068 (PALS RI)]by the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant Nos. XDA25030200 and XDA25010100)supported by COST (European Cooperation in Science and Technology) through Action CA21128 PROBONO (PROton BOron Nuclear Fusion: from energy production to medical applicatiOns)
文摘Recent experiments at the National Ignition Facility and theoretical modeling suggest that side stimulated Raman scattering(SSRS)instability could reduce laser–plasma coupling and generate considerable fluxes of suprathermal hot electrons under interaction conditions envisaged for direct-drive schemes for inertial confinement fusion.Nonetheless,SSRS remains to date one of the least understood parametric instabilities.Here,we report the first angularly and spectrally resolved measurements of scattered light at laser intensities relevant for the shock ignition scheme(I×10^(16)W/cm^(2)),showing significant SSRS growth in the direction perpendicular to the laser polarization.Modification of the focal spot shape and orientation,obtained by using two different random phase plates,and of the density gradient of the plasma,by utilizing exploding foil targets of different thicknesses,clearly reveals a different dependence of backward SRS(BSRS)and SSRS on experimental parameters.While convective BSRS scales with plasma density scale length,as expected by linear theory,the growth of SSRS depends on the spot extension in the direction perpendicular to laser polarization.Our analysis therefore demonstrates that under current experimental conditions,with density scale lengths L_(n)≈60–120μm and spot sizes FWHM≈40–100μm,SSRS is limited by laser beam size rather than by the density scale length of the plasma.
基金funded by the European Union via the Euratom Research and Training Program(Grant Agreement No.101052200-EUROfusion)funding from LASERLAB-EUROPE(Grant Agreement No.871124,European Union’s Horizon 2020 Research and Innovation Program)+5 种基金supported in part by the United States Department of Energy under Grant No.DE-FG02-93ER40773We also acknowledge support from Grant No.PID2021-125389OA-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER,UEby“ERDF A Way of Making Europe”by the European Union and Unidad de Investigación Consolidada of Junta de Castilla y León UIC 167supported in part by the National Natural Science Foundation of China under Grant No.12375125the Fundamental Research Funds for the Central Universitiesthe support of the Czech Science Foundation through Grant No.GACR24-11398S.
文摘Driving of the nuclear fusion reaction p+^(11)B3α+8.7 MeV under laboratory conditions by interaction between high-power laser pulses and matter has become a popular field of research,owing to its numerous potential applications:as an alternative to deuterium-tritium for fusion energy production,astrophysics studies,and alpha-particle generation for medical treatment.One possible scheme for laser-driven p-^(11)B reactions is to direct a beam of laser-accelerated protons onto a boron(B)sample(the so-called“pitcher-catcher”scheme).This technique has been successfully implemented on large high-energy lasers,yielding hundreds of joules per shot at low repetition.We present here a complementary approach,exploiting the high repetition rate of the VEGA III petawatt laser at CLPU(Spain),aiming at accumulating results from many interactions at much lower energy,to provide better control of the parameters and the statistics of the measurements.Despite a moderate energy per pulse,our experiment allowed exploration of the laser-driven fusion process with tens(up to hundreds)of laser shots.The experiment provided a clear signature of the reactions involved and of the fusion products,accumulated over many shots,leading to an improved optimization of the diagnostics for experimental campaigns of this type.In this paper,we discuss the effectiveness of laser-driven p-11B fusion in the pitcher-catcher scheme,at a high repetition rate,addressing the challenges of this experimental scheme and highlighting its critical aspects.Our proposed methodology allows evaluation of the performance of this scheme for laser-driven alpha particle production and can be adapted to high-repetition-rate laser facilities with higher energy and intensity.
基金This work has been funded by the European Union via the Euratom Research and Training Programme(Grant Agreement No 101052200-EUROfusion).
文摘Porous materials offer unique possibilities for the production of plasmas with controlled density profiles for experiments on laser–matter interaction.They are of growing relevance to many applications,such as inertial confinement fusion,fundamental research,and secondary sources.Understanding the processes of transformation of a porous solid into a plasma is of fundamental interest and is needed for producing materials with desired properties.
文摘The thermodynamic properties of boron nitride under extreme pressures and temperatures are of great interest and importance for materials science and inertial confinement fusion physics,but they are poorly understood owing to the challenges of performing experiments and realizing ab initio calculations.Here,we report the first shock Hugoniot data on hexagonal boron nitride at pressures of 5–16 Mbar,using hohlraum-driven shock waves at the SGIII-p laser facility in China.Our density functional theory molecular dynamics calculations closely match experimental data,validating the equations of state for modeling the shock response of boron nitride and filling a crucial gap in the knowledge of boron nitride properties in the region of multi-Mbar pressures and eV temperatures.The results presented here provide fundamental insights into boron nitride under the extreme conditions relevant to inertial confinement fusion,hydrogen–boron fusion,and high-energy-density physics.
基金funding from the European Union’s Horizon 2020 research and innovation program under Grant Agreement No.871124 Laserlab-Europeby Grant No.ANR-17-CE30-0026-Pinnacle from the Agence Nationale de la Recherche.
文摘We have recently proposed a new technique of plasma tailoring by laser-driven hydrodynamic shockwaves generated on both sides of a gas jet[Marquès et al.,Phys.Plasmas 28,023103(2021)].In a continuation of this numerical work,we study experimentally the influence of the tailoring on proton acceleration driven by a high-intensity picosecond laser in three cases:without tailoring,by tailoring only the entrance side of the picosecond laser,and by tailoring both sides of the gas jet.Without tailoring,the acceleration is transverse to the laser axis,with a low-energy exponential spectrum,produced by Coulomb explosion.When the front side of the gas jet is tailored,a forward acceleration appears,which is significantly enhanced when both the front and back sides of the plasma are tailored.This forward acceleration produces higher-energy protons,with a peaked spectrum,and is in good agreement with the mechanism of collisionless shock acceleration(CSA).The spatiotemporal evolution of the plasma profile is characterized by optical shadowgraphy of a probe beam.The refraction and absorption of this beam are simulated by post-processing 3D hydrodynamic simulations of the plasma tailoring.Comparison with the experimental results allows estimation of the thickness and near-critical density of the plasma slab produced by tailoring both sides of the gas jet.These parameters are in good agreement with those required for CSA.
文摘The discovery of chirped pulse amplification has led to great improvements in laser technology,enabling energetic laser beams to be compressed to pulse durations of tens of femtoseconds and focused to a few micrometers.Protons with energies of tens of MeV can be accelerated using,for instance,target normal sheath acceleration and focused on secondary targets.Under such conditions,nuclear reactions can occur,with the production of radioisotopes suitable for medical application.The use of high-repetition lasers to produce such isotopes is competitive with conventional methods mostly based on accelerators.In this paper,we study the production of^(67)Cu,^(63)Zn,^(18)F,and^(11)C,which are currently used in positron emission tomography and other applications.At the same time,we study the reactions^(10)B(p,α)^(7)Be and^(70)Zn(p,4n)^(67)Ga to put further constraints on the proton distributions at different angles,as well as the reaction^(11)B(p,α)^(8)Be relevant for energy production.The experiment was performed at the 1 PW laser facility at VegaⅢin Salamanca,Spain.Angular distributions of radioisotopes in the forward(with respect to the laser direction)and backward directions were measured using a high purity germanium detector.Our results are in reasonable agreement with numerical estimates obtained following the approach of Kimura and Bonasera[Nucl.Instrum.Methods Phys.Res.,Sect.A 637,164–170(2011)].
文摘We report novel results on top-down percussion drilling in different glasses with femtosecond laser GHz-bursts.Thanks to this particular regime of light–matter interaction,combining non-linear absorption and thermal cumulative effects,we obtained crack-free holes of aspect ratios exceeding 30 in sodalime and 70 in fused silica.The results are discussed in terms of inner wall morphology,aspect ratio and drilling speed.
基金Supported by Heber Biotec,Havana(for providing products and reagents)and the Ministry of Public Health of Cuba(for hospital facilities and general medical care of patients)
文摘AIM: To compare the efficacy and safety of recombinant streptokinase(rSK) vs hydrocortisone acetate-based suppositories in acute hemorrhoidal disease.METHODS: A multicenter(11 sites), randomized(1:1:1), open, controlled trial with parallel groups was performed. All participating patients gave their written,informed consent. After inclusion, patients with acute symptoms of hemorrhoids were centrally randomized to receive, as outpatients, by the rectal route, suppositories of rSK 200000 IU of one unit every 8 h(first 3 units)and afterwards every 12 h until 8 administrations were completed(schedule A), one unit every 8 h until 6 units were completed(schedule B), or 25 mg hydrocortisone acetate once every 8 h up to a maximum of 24 administrations. Evaluations were performed at 3, 5,and 10 d post-inclusion. The main end-point was the 5thday response(disappearance of pain and bleeding, and≥ 70% reduction of the lesion size). Time to response and need for thrombectomy were secondary efficacy variables. Adverse events were also evaluated.RESULTS: Groups were homogeneous with regards to demographic and baseline characteristics. Fifth day complete response rates were 156/170(91.8%; 95%CI:87.3-96.2), 155/170(91.2%; 95%CI: 86.6%-95.7%),and 46/170(27.1%; 95%CI: 20.1%-34.0%) with rSK(schedule A and B) and hydrocortisone acetate suppositories, respectively. These 64.6% and 63.9%differences(95%CI: 56.7%-72.2% and 55.7%-72.0%)were highly significant(P < 0.001). This advantage was detected since the early 3rd day evaluation(68.8% and64.1% vs 7.1% for the rSK and active control groups,respectively; P < 0.001) and was maintained even at the late 10 th day assessment(97.1% and 93.5% vs67.1% for rSK and hydrocortisone acetate, respectively;P < 0.001). Time to response was 3 d(95%CI: 2.9-3.1)for both rSK groups and 10 d(95%CI: 9.3-10.7) in the hydrocortisone acetate group. This difference was highly significant(P < 0.001). All subgroup stratified analyses(with or without thrombosis and hemorrhoid classification) showed a statistically significant advantage for the rSK groups. Thrombectomy was necessary in4/251 and 14/133 patients with baseline thrombosis in the rSK and hydrocortisone acetate groups, respectively(P < 0.001). There were no adverse events attributable to the experimental treatment.CONCLUSION: rSK suppositories showed a significant advantage over a widely-used over-the-counter hydrocortisone acetate preparation for the treatment of acute hemorrhoidal illness, as well as having an adequate safety profile.
基金We acknowledge fruitful discussions with H.P´epin(INRS),V.M´eot,L.Gremillet,X.Davoine(CEA),S.Orlando(INAF),C.Guerrero(Universidad de Sevilla),and Y.Caristan(Universit´e Paris-Saclay).This project received funding from the European Research Council(ERC)under the European Union’s Horizon 2020 Research and Innovation Programme(Grant Agreement No.787539),and was partly conducted within the LABEX Plas@Par project and supported by Grant Nos.11-IDEX-0004-02 and an ANR-17-CE30-0026 PiNNaCLE grant from Agence Nationale de la Recherche(France).I.P.acknowledges the support of ISF Grant No.1135/15.The research leading to these results is supported by Extreme Light Infrastructure Nuclear Physics(ELI-NP)Phase I,a project cofinanced by the Romanian Government and the European Union through the European Regional Development Fund.
文摘With the much-anticipated multi-petawatt(PW)laser facilities that are coming online,neutron sources with extreme fluxes could soon be in reach.Such sources would rely on spallation by protons accelerated by the high-intensity lasers.These high neutron fluxes would make possible not only direct measurements of neutron capture andβ-decay rates related to the r-process of nucleosynthesis of heavy elements,but also such nuclear measurements in a hot plasma environment,which would be beneficial for s-process investigations in astrophysically relevant conditions.This could,in turn,finally allow possible reconciliation of the observed element abundances in stars and those derived from simulations,which at present show large discrepancies.Here,we review a possible pathway to reach unprecedented neutron fluxes using multi-PW lasers,as well as strategies to perform measurements to investigate the r-and s-processes of nucleosynthesis of heavy elements in cold matter,as well as in a hot plasma environment.
基金the DFG(Project No.PU 213/9),EPSRC Grant No.EP/P026796/1the Ministry of Science and Higher Education of the Russian Federation(Agreement with Joint Institute for High Temperatures RAS No 075-15-2020-785,dated September 23,2020).
文摘Direct laser acceleration(DLA)of electrons in a plasma of near-critical electron density(NCD)and the associated synchrotron-like radiation are discussed for moderate relativistic laser intensity(normalized laser amplitude a0≤4.3)and ps length pulse.This regime is typical of kJ PW-class laser facilities designed for high-energy-density(HED)research.In experiments at the PHELIX facility,it has been demonstrated that interaction of a 1019 W/cm2 sub-ps laser pulse with a sub-mm length NCD plasma results in the generation of high-current well-directed superponderomotive electrons with an effective temperature ten times higher than the ponderomotive potential[Rosmej et al.,Plasma Phys.Controlled Fusion 62,115024(2020)].Three-dimensional particle-in-cell simulations provide good agreement with the measured electron energy distribution and are used in the current work to study synchrotron radiation from the DLA-accelerated electrons.The resulting x-ray spectrum with a critical energy of 5 keV reveals an ultrahigh photon number of 731011 in the 1–30 keV photon energy range at the focused laser energy of 20 J.Numerical simulations of betatron x-ray phase contrast imaging based on the DLA process for the parameters of a PHELIX laser are presented.The results are of interest for applications in HED experiments,which require a ps x-ray pulse and a high photon flux.
基金This work was carried out within the framework of the EUROfusion Consortium,funded by the European Union via the Euratom Research and Training Programme(Grant No.101052200-EUROfusion)Views and opinions expressed are however those of the authors only and do not necessarily reflect those of the European Union or the European Commission.Neither the European Union nor the European Commission can be held responsible for them.The involved teams have operated within the framework of the Enabling Research Project:Grant No.ENR-IFE.01.CEA“Advancing shock ignition for direct-drive inertial fusion.”The work was also supported by the Natural Sciences and Engineering Research Council of Canada(Grant No.RGPIN-2019-05013)+5 种基金The authors acknowledge support of the PALS Infrastructure within the MŠMT(MEYS)project Grant No.LM2023068Staff members of the PALS Research Center appreciate financial support(Grant No.LM2023068)from the Czech Ministry of Education,Youth and Sports facilitating operation of the PALS facilityThe work of JIHT RAS team was supported by the Ministry of Science and Higher Education of the Russian Federation(State Assignment No.075-01129-23-00)The work at NRMU MEPhI was supported by the Ministry of Science and Higher Education of the Russian Federation(Agreement No.075-15-2021-1361)This project has received funding from the CNR funded Italian research Network ELI-Italy(D.M.No.63108.08.2016)This work was funded by United Kingdom EPSRC Grants No.EP/P026796/1 and No.EP/L01663X/1.The results presented in this paper are based on work carried out between September 2018 and December 2021.
文摘In an experiment carried out at the Prague Asterix Laser System at laser intensities relevant to shock ignition conditions(I>10^(16) W/cm^(2)),the heating and transport of hot electrons were studied by using several complementary diagnostics,i.e.,K_(α)time-resolved imaging,hard x-ray filtering(a bremsstrahlung cannon),and electron spectroscopy.Ablators with differing composition from low Z(parylene N)to high Z(nickel)were used in multilayer planar targets to produce plasmas with different coronal temperature and collisionality and modify the conditions of hot-electron generation.The variety of available diagnostics allowed full characterization of the population of hot electrons,retrieving their conversion efficiency,time generation and duration,temperature,and angular divergence.The obtained results are shown to be consistent with those from detailed simulations and similar inertial confinement fusion experiments.Based on the measured data,the advantages,reliability,and complementarity of the experimental diagnostics are discussed.
基金The XFEL experiments were performed at the BL3 of SACLA with the approval of the Japan Synchrotron Radiation Research Institute(JASRI)(Proposals Nos.2014A8045,and 2014B8068)This research was partially supported by grants from Grants-in-Aid for Scientific Research(Kakenhi Grant Nos.15H02153 and 17K05729)+1 种基金the Core-to-Core Program on International Alliance for Material Science in Extreme States with High Power Laser of the Japan Society for the Promotion of Science(JSPS),from the X-ray Free Electron Laser Priority Strategy Program of the MEXT,contract 12005014,and within the state assignment of FASO of Russia(theme N01201357846)The part of work was supported by the Agence Nationale de la Recherche in the frame of the ANR project TurboHEDP(ANR-15-CE30-0011).
文摘We present new diagnostics for use in optical laser pump-X-ray Free Electron Laser(XFEL)probe experiments to monitor dimensions,intensity profile and focusability of the XFEL beam and to control initial quality and homogeneity of targets to be driven by optical laser pulse.By developing X-ray imaging,based on the use of an LiF crystal detector,we were able to measure the distribution of energy inside a hard X-ray beam with unprecedented high spatial resolution(~1 mm)and across a field of view larger than some millimetres.This diagnostic can be used in situ,provides a very high dynamic range,has an extremely limited cost,and is relatively easy to be implemented in pump-probe experiments.The proposed methods were successfully applied in pump-probe experiments at the SPring-8 Angstrom Compact free electron LAser(SACLA)XFEL facility and its potential was demonstrated for current and future High Energy Density Science experiments.
基金funding from the European Union’s Horizon 2020 research and innovation programme through the European IMPULSE project under grant agreement No.871161 and LASERLAB-EUROPE V under grant agreement No.871124from grant PDC2021-120933-I00 funded by MCIN/AEI/10.13039/501100011033 and by the European Union Next Generation EU/PRTR+4 种基金from grant PID2021-125389OA-I00 funded by MCIN/AEI/10.13039/501100011033/FEDER,UE and by‘ERDF A way of making Europe’by the European Union and in addition to Unidad de Investigacion Consolidada de la Junta de Castilla y Leon No.CLP087U16The UPM47 campaign was funded through IOSIN,Nucleu PN-IFIN-HH 23-26 Code PN 2321the ELI-NP Phase II,a project co-financed by the Romanian Government and the European Union through the European Regional Development Fund and the Competitiveness Operational Programme(1/07.07.2016,COP,ID 1334)This research was funded,in part,by the French Agence Nationale de la Recherche(ANR),Project No.ANR-22-CE30-0044supported by the Ministry of Youth and Sports of the Czech Republic(Project Nos.LM2023068 and LM2018114(PALS RI)).
文摘We present a novel scheme for rapid quantitative analysis of debris generated during experiments with solid targets following relativistic laser–plasma interaction at high-power laser facilities.Results are supported by standard analysis techniques.Experimental data indicate that predictions by available modelling for non-mass-limited targets are reasonable,with debris of the order of hundreds ofμg per shot.We detect for the first time two clearly distinct types of debris emitted from the same interaction.A fraction of the debris is ejected directionally,following the target normal(rear and interaction side).The directional debris ejection towards the interaction side is larger than on the side of the target rear.The second type of debris is characterized by a more spherically uniform ejection,albeit with a small asymmetry that favours ejection towards the target rear side.
基金This work has been carried out within the framework of the EUROfusion Enabling Research Project No.AWP17-ENR-IFECEA-01“Preparation and Realization of European Shock Ignition Experiments”and has received funding from the Euratom Research and Training Program 2014-2018 under Grant Agreement No.633053.The views and opinions expressed herein do not necessarily reflect those of the European Commission.
文摘We describe two numerical investigations performed using a 3D plasma Monte-Carlo code,developed to study hot-electron transport in the context of inertial confinement fusion.The code simulates the propagation of hot electrons in ionized targets,using appropriate scattering differential cross sections with free plasma electrons and ionized or partially ionized atoms.In this paper,we show that a target in the plasma state stops and diffuses electrons more effectively than a cold target(i.e.,a target under standard conditions in which ionization is absent).This is related to the fact that in a plasma,the nuclear potential of plasma nuclei has a greater range than in the cold case,where the screening distance is determined by the electronic structure of atoms.However,in the ablation zone created by laser interaction,electrons undergo less severe scattering,counterbalancing the enhanced diffusion that occurs in the bulk.We also show that hard collisions,i.e.,collisions with large polar scattering angle,play a primary role in electron beam diffusion and should not be neglected.An application of the plasma MonteCarlo model to typical shock ignition implosions suggests that hot electrons will not give rise to any preheating concerns if their Maxwellian temperature is lower than 25–30 keV,although the presence of populations at higher temperatures must be suppressed.This result does not depend strongly on the initial angular divergence of the electron beam set in the simulations.
基金This work has been carried out within the framework of the EUROfusion Enabling Research Project No.AWP17-ENR-IFECEA-01“Preparation and Realization of European Shock Ignition Experiments”and has received funding from the Euratom Research and Training Program 2014-2018 under Grant Agreement No.633053The views and opinions expressed herein do not necessarily reflect those of the European Commission.The authors thank Professors Vladimir Tikhonchuk and Stefano Atzeni for many useful discussions.We also thank the anonymous reviewers for their constructive comments.
文摘We describe the development of a 3D Monte-Carlo model to study hot-electron transport in ionized or partially ionized targets,considering regimes typical of inertial confinement fusion.Electron collisions are modeled using a mixed simulation algorithm that considers both soft and hard scattering phenomena.Soft collisions are modeled according to multiple-scattering theories,i.e.,considering the global effects of the scattering centers on the primary particle.Hard collisions are simulated by considering a two-body interaction between an electron and a plasma particle.Appropriate differential cross sections are adopted to correctly model scattering in ionized or partially ionized targets.In particular,an analytical form of the differential cross section that describes a collision between an electron and the nucleus of a partially ionized atom in a plasma is proposed.The loss of energy is treated according to the continuous slowing down approximation in a plasma stopping power theory.Validation against Geant4 is presented.The code will be implemented as a module in 3D hydrodynamic codes,providing a basis for the development of robust shock ignition schemes and allowing more precise interpretations of current experiments in planar or spherical geometries.
基金supported by the CEA/DAM Laser Plasma Experiments Validation Projectthe CEA/DAM Basic Technical and Scientific Studies Project+4 种基金supported by the National Sciences and Engineering Research Council of Canada(NSERC)(Grant Nos.RGPIN-2023-05459 and ALLRP 556340-20)Compute Canada(Job pve-323-ac)the Canada Foundation for Innovation(CFI)financial support by the IdEx University of Bordeaux/Grand Research Program“GPR LIGHT”the Graduate Program on Light Sciences and Technologies of the University of Bordeaux。
文摘An analytical model of current propagation in a helical coil with varying geometry is developed.It can be used for post-acceleration and post-focusing of ions produced via laser-driven target normal sheath acceleration and generation of electromagnetic pulses.We calculate the current that propagates in a helical coil and suggest a method for improving its dispersion properties using a screening tube and with pitch and radius variation.The electromagnetic fields calculated with the analytical model are in agreement with particle-in-cell simulations.The model provides insights into the physics of current propagation in helical coils with varying geometries and enables a numerical implementation for rapid proton spectrum computations,which facilitate the design of such coils for future experiments.
