Based on the finite element-discrete element numerical method,a numerical model of fracture propagation in deflagration fracturing was established by considering the impact of stress wave,quasi-static pressure of expl...Based on the finite element-discrete element numerical method,a numerical model of fracture propagation in deflagration fracturing was established by considering the impact of stress wave,quasi-static pressure of explosive gas,and reflection of stress wave.The model was validated against the results of physical experiments.Taking the shale reservoirs of Silurian Longmaxi Formation in Luzhou area of the Sichuan Basin as an example,the effects of in-situ stress difference,natural fracture parameters,branch wellbore spacing,delay detonation time,and angle between branch wellbore and main wellbore on fracture propagation were identified.The results show that the fracture propagation morphology in deflagration fracturing is less affected by the in-situ stress difference when it is 5-15 MPa,and the tendency of fracture intersection between branch wellbores is significantly weakened when the in-situ stress difference reaches 20 MPa.The increase of natural fracture length promotes the fracture propagation along the natural fracture direction,while the increase of volumetric natural fracture density and angle limits the fracture propagation area and reduces the probability of fracture intersection between branch wells.The larger the branch wellbore spacing,the less probability of the fracture intersection between branch wells,allowing for the fracture propagation in multiple directions.Increasing the delay detonation time decreases the fracture spacing between branch wellbores.When the angle between the branch wellbore and the main wellbore is 45°and 90°,there is a tendency of fracture intersection between branch wellbores.展开更多
Hyperbranched polymer with highly branched three-dimensional topological structure, a large number of end groups, and multifaceted functionalities have gained much attention, while polymers with aggregation-induced em...Hyperbranched polymer with highly branched three-dimensional topological structure, a large number of end groups, and multifaceted functionalities have gained much attention, while polymers with aggregation-induced emission(AIE) properties become a group of popular luminescent materials recently. The design and synthesis of AIE-active hyperbranched polymers, which combine the advantages of these two types of materials, are attractive but challenging. In this work, four hyperbranched poly(tetrahydropyrimidine)s were synthesized from the metal-free room temperature multicomponent tandem polymerization of diester group-activated internal alkyne,polyfunctional aromatic amines, and formaldehyde in methanol under the catalysis of acetic acid. Through different monomer combination and controlling the monomer loading order, hyperbranched polymers with various topological structures as well as sequences of different functional groups in the polymer backbone were obtained with high molecular weights(up to 3.0 × 10~4 g/mol) in high yields(up to 98%). The hyperbranched poly(tetrahydropyrimidine) emitted faintly in solution, while its luminescence was notably enhanced in the aggregated state, suggesting its typical aggregation-induced emission property. It is anticipated that the multicomponent polymerization may provide a synthetic platform for the construction of hyperbranched polyheterocycles with diverse structures and functionalities.展开更多
Azide-alkyne click polymerization has become a powerful tool for polymer synthesis.However,the click polymerization between internal alkynes and azides is rarely utilized to prepare functional polymers.In this work,th...Azide-alkyne click polymerization has become a powerful tool for polymer synthesis.However,the click polymerization between internal alkynes and azides is rarely utilized to prepare functional polymers.In this work,the polymerization reactions of activated internal alkyne monomers of tris(2-butynoate)s(1)with tetraphenylethene-containing diazides(2)were performed in dimethylformamide(DMF)under simple heating,affording four hyperbranched poly(methyltriazolylcarboxylate)s(hb-PMTCs)with high molecular weights(A4W up to 2.4 x 104)and regioregularities(up to 83.9%)in good yields.The hb-PMTCs are soluble in common organic solvents,and thermally stable with 5%weight loss temperatures up to 400℃.They are non-emissive in dilute solution,but become highly emissive in aggregated state,exhibiting aggregationinduced emission characteristics.The polymers can generate fluorescent photopatterns with high resolution,and can work as fluorescent sensors to detect nitroaromatic explosive with high sensitivity.展开更多
The integration and development of grass-roots Party organizations and accurate poverty alleviation is the focus in social development in the new period. This is also a new measure explored by the CPC Central Committe...The integration and development of grass-roots Party organizations and accurate poverty alleviation is the focus in social development in the new period. This is also a new measure explored by the CPC Central Committee in the new historical period to solve rural reform and extricate the poor from poverty,and can effectively enhance the enthusiasm of the masses in poverty alleviation and development work. Xundian Hui and Yi Autonomous County is located in the mountainous area of northeast Yunnan Province. It is one of the 592 national key counties for poverty alleviation and development and one of the 38 continuous development counties in Wumeng Mountain area. Since the implementation of the accurate poverty alleviation strategy,Xundian County insists on getting rid of poverty to grasp the overall situation of county economic and social development,focus on the actual situation of the county people,and conscientiously grasp the key of industrial poverty alleviation. It regards industry as the fundamental driving force to realize poverty alleviation from " blood transfusion" to " blood creation",and innovates the model of " Party branch +" to help the poor out of poverty by industry. It has selected 187 agricultural enterprises( cooperatives,large households) to achieve full coverage of all registered poor households,and achieved remarkable results. It has realized that each poor village has one to two leading industries,and each poor household has one to two industrial income projects,having led 30 500 poor households to increase their average income by more than 1 850 yuan. The final incidence of poverty decreased from 26. 93% in 2014 to 0. 35% at the end of 2017,becoming one of the first counties in Yunnan Province to get rid of poverty. It is also the only county in Yunnan Province that has won the Antipoverty Organization Innovation Award of the State Council. Based on field research and interviews,this paper analyzes and summarizes the specific methods,main achievements,practical experience and popularization and application measures of Xundian County " Party Branch +" to promote industrial poverty alleviation,so as to provide necessary reference for accurate poverty reduction and poverty alleviation in similar mountainous areas of Yunnan Province and other provinces.展开更多
Branch number(BN)is an important agronomic attribute related to the plant architecture,adaptability,and yield of soybean.To date,few studies ofBNhave been conducted to elucidate its genetic background.We aimed to loca...Branch number(BN)is an important agronomic attribute related to the plant architecture,adaptability,and yield of soybean.To date,few studies ofBNhave been conducted to elucidate its genetic background.We aimed to localize genetic factors affecting BN using segregating populations derived fromthe high-branching cultivar‘Kennong24’(KN24)and the low-branching cultivar‘Kenfeng19’(KF19).Composite interval mapping analysis detected a QTL(qBN-1)on chromosome 6 between the SSR markers BARCSOYSSR_06_0993 and BARCSOYSSR_06_1070 using an F2 population.To fine-map qBN-1,a RIL population was developed and genotyped with 14 SSRmarkers located in the QTL region.qBN-1 was localized to a 115.67-kb interval flanked by markers BARCSOYSSR_06_1048 and BARCSOYSSR_06_1053.The QTL was further confirmed using backcross populations of size 1305(BC2F2 with KN24 as a recurrent parent)and 1712(BC3F2 with KF19 as a recurrent parent).The fine-mapping region of qBN-1 contained only two candidate genes,Glyma.06G208800 and Glyma.06G208900,whose expression patterns were investigated by qRT-PCR.Compared to Glyma.06G208800 gene expression,Glyma.06G208900 showed the highest expression of the two genes and showed a significant difference in expression between high-and low-branching genotypes in either axillary meristem or shoot apical meristem,and showed opposite expression patterns in the two tissues at V4 and R1 stages.These results identify Glyma.06G208900 as a novel candidate gene controlling BN.Taken together,the results of this study provide a foundation for cloning and functional analysis of the qBN-1 gene and for the improvement of BN bymarker-assisted selection in soybean breeding.展开更多
Presented are the ideas and proposals in regards to the pooling of by RAS, SB, ISTP, and CSSAR,CAS toward coordinated usage of existing ground-based and orbiting helio-geophysical observatories, single large installat...Presented are the ideas and proposals in regards to the pooling of by RAS, SB, ISTP, and CSSAR,CAS toward coordinated usage of existing ground-based and orbiting helio-geophysical observatories, single large installations as well as creating, forecasting services and new observing facilities, in the interests of achieving a profitable activity of the China-Russia Joint Research Center on Space Weather (JRCSW).展开更多
In recent decades, substantial increase in average weight of individuals has been seen in rich countries. Such changes are the result of significant changes in pattern of people’s lives. One of these issues is increa...In recent decades, substantial increase in average weight of individuals has been seen in rich countries. Such changes are the result of significant changes in pattern of people’s lives. One of these issues is increasing levels in consumption of fast foods or processed foods. According to experts, the consumption of processed foods, because of having high-calories and trans-fatty acids, is fattening and harmful. In this study, the researchers after obtaining permission from the ethics committee and head of the School of Nursing, introduced themselves to nursing students then, samples were randomly selected among those who are eligible for the study. Before performing to complete the questionnaire and relevant experiments, testimonial were asked from the subjects. At the end of the study, results were suggested that, levels of Serum folate between males and females and also among married and single people were equivalent. Level of Serum folate among those students who usually have anemia in their families is significantly lower than those ones who have not anemia in their families (P = 0.003). There was a significant relationship between age and semester with levels of folate (P i.e. by increasing age and educational terms, levels of serum folate would be reduced. The level of serum folate among students who smoke is lesser than those do not (P = 0.001).展开更多
Actin is a highly conserved cytoskeletal protein that is found in essentially all eukaryotic cells,which plays a paramount role in several basic functions of the organism, such as the maintenance of cellshape, cell di...Actin is a highly conserved cytoskeletal protein that is found in essentially all eukaryotic cells,which plays a paramount role in several basic functions of the organism, such as the maintenance of cellshape, cell division, cell mobility and muscle contraction. However, little is known about actin gene family inChinese amphioxus (Branchiostoma belcheri). Here we systemically analyzed the actin genes family inBranchiostoma belched and found that amphioxus contains 33 actin genes. These genes have undergoneextensive expansion through tandem duplications by phylogenetic analysis. In addition, we also providedevidence indicating that actin genes have divergent functions by specializing their EST data in both Bran-chiostoma belched and Branchiostoma florida. Our results provided an alternative explanation for the evolu-tion of actin genes, and gave new insights into their functional roles.展开更多
Introduction: Sickle cell disease is a public health problem in sub-Saharan Africa. A national referral center for the management of infants and pregnant women with sickle cell disease (CPMI-NFED) was created three de...Introduction: Sickle cell disease is a public health problem in sub-Saharan Africa. A national referral center for the management of infants and pregnant women with sickle cell disease (CPMI-NFED) was created three decades ago in Cotonou, in the south of Benin with two regional branches including that of Parakou in the North for better access of patients to specialized care. This work is a review of five years of activities in order to describe the epidemiological, clinical, hematological and evolutionary profiles of the children followed up in the said branch. Method: This was a descriptive and retrospective cross-sectional study on the medical records of children with sickle cell disease, followed up at the regional branch of CPMI-NFED in Borgou/Alibori from June 1, 2017 to May 31, 2022. The variables studied were epidemiological, clinical, biological and evolutionary. Results: A total of 101 children with sickle cell disease were included in the study, including 78 homozygous SS (77.2%) and 23 heterozygous SC (22.8%). Their mean age at inclusion was 51.2 ± 37.6 months [6 - 204]. The sex ratio was 1.4. Vaso-occlusive crises were the main diagnostic circumstances in 42.3% of homozygotes. More than half of the children (51.5%) had a regular follow-up. The average baseline level of hemoglobin (Hb) in homozygous children was 8.8 ± 1.4 g/dl [5.8 - 11.5];and the rate of Hb S varied between 61.9 and 94.7%. In heterozygous SC children, the mean baseline level of Hb was 10.7 ± 0.6 g/dl [9.7 - 11.5]. Acute complications observed during follow-up were dominated by pneumonia and vaso-occlusive crises in both phenotypes. The overall mortality was 3% and only affected homozygous patients. Conclusion: On average, three out of four children were homozygous in our cohort. The main acute complications were infectious and vaso-occlusive. The mortality only affected homozygous carriers. Specialized follow-up has contributed to improving the quality of life of children with sickle cell disease. This could be implemented on a large scale for better survival of children with sickle cell disease.展开更多
How ecological environmental monitoring provides scientific and technological strength for ecological environmental management was studied.In recent years,the Ecological Environment Monitoring Station of Yanshan Branc...How ecological environmental monitoring provides scientific and technological strength for ecological environmental management was studied.In recent years,the Ecological Environment Monitoring Station of Yanshan Branch,Wenshan Prefecture Ecological Environment Bureau,Yunnan Province has developed into a provincial environmental education base,a provincial science education base,and a national environmental protection facility open to the public by relying on monitoring equipment and facilities,personnel training,monitoring and law enforcement interaction,analysis of abnormal data,and countermeasures and suggestions were put forward for the problems in the development.展开更多
基金Supported by the National Natural Science Foundation of China(52374004)National Key R&D Program of China(2023YFF0614102,2023YFE0110900).
文摘Based on the finite element-discrete element numerical method,a numerical model of fracture propagation in deflagration fracturing was established by considering the impact of stress wave,quasi-static pressure of explosive gas,and reflection of stress wave.The model was validated against the results of physical experiments.Taking the shale reservoirs of Silurian Longmaxi Formation in Luzhou area of the Sichuan Basin as an example,the effects of in-situ stress difference,natural fracture parameters,branch wellbore spacing,delay detonation time,and angle between branch wellbore and main wellbore on fracture propagation were identified.The results show that the fracture propagation morphology in deflagration fracturing is less affected by the in-situ stress difference when it is 5-15 MPa,and the tendency of fracture intersection between branch wellbores is significantly weakened when the in-situ stress difference reaches 20 MPa.The increase of natural fracture length promotes the fracture propagation along the natural fracture direction,while the increase of volumetric natural fracture density and angle limits the fracture propagation area and reduces the probability of fracture intersection between branch wells.The larger the branch wellbore spacing,the less probability of the fracture intersection between branch wells,allowing for the fracture propagation in multiple directions.Increasing the delay detonation time decreases the fracture spacing between branch wellbores.When the angle between the branch wellbore and the main wellbore is 45°and 90°,there is a tendency of fracture intersection between branch wellbores.
基金financially supported by the National Natural Science Foundation of China (Nos. 21822102, 21774034, 21490573, 21490574, and 21788102)the Natural Science Foundation of Guangdong Province (Nos. 2016A030306045 and 2016030312002)the Innovation and Technology Commission of Hong Kong (No. ITC-CNERC14SC01)
文摘Hyperbranched polymer with highly branched three-dimensional topological structure, a large number of end groups, and multifaceted functionalities have gained much attention, while polymers with aggregation-induced emission(AIE) properties become a group of popular luminescent materials recently. The design and synthesis of AIE-active hyperbranched polymers, which combine the advantages of these two types of materials, are attractive but challenging. In this work, four hyperbranched poly(tetrahydropyrimidine)s were synthesized from the metal-free room temperature multicomponent tandem polymerization of diester group-activated internal alkyne,polyfunctional aromatic amines, and formaldehyde in methanol under the catalysis of acetic acid. Through different monomer combination and controlling the monomer loading order, hyperbranched polymers with various topological structures as well as sequences of different functional groups in the polymer backbone were obtained with high molecular weights(up to 3.0 × 10~4 g/mol) in high yields(up to 98%). The hyperbranched poly(tetrahydropyrimidine) emitted faintly in solution, while its luminescence was notably enhanced in the aggregated state, suggesting its typical aggregation-induced emission property. It is anticipated that the multicomponent polymerization may provide a synthetic platform for the construction of hyperbranched polyheterocycles with diverse structures and functionalities.
基金the National Natural Science Foundation of China(Nos.21875152 and 21404077)the Natural Science Foundation of the Jiangsu Higher Education Institutions of China(No.17KJB150034)+3 种基金the Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates,Guangzhou 510640,China(South China University of Technology)(No.2019B030301003)the Priority Academic Program Development of Jiangsu High Education Institutions(PAPD).M.N.L.and Q.Z.Z.thank the financial support from Undergraduate Training Program for Innovation and Entrepreneurship,Soochow University(No.2018xj032)H.K.L.acknowledges the supports from Jiangsu Planned Projects for Postdoctoral Research Funds(No.1501023B)China Postdoctoral Science Foundation(No.2016M591906).
文摘Azide-alkyne click polymerization has become a powerful tool for polymer synthesis.However,the click polymerization between internal alkynes and azides is rarely utilized to prepare functional polymers.In this work,the polymerization reactions of activated internal alkyne monomers of tris(2-butynoate)s(1)with tetraphenylethene-containing diazides(2)were performed in dimethylformamide(DMF)under simple heating,affording four hyperbranched poly(methyltriazolylcarboxylate)s(hb-PMTCs)with high molecular weights(A4W up to 2.4 x 104)and regioregularities(up to 83.9%)in good yields.The hb-PMTCs are soluble in common organic solvents,and thermally stable with 5%weight loss temperatures up to 400℃.They are non-emissive in dilute solution,but become highly emissive in aggregated state,exhibiting aggregationinduced emission characteristics.The polymers can generate fluorescent photopatterns with high resolution,and can work as fluorescent sensors to detect nitroaromatic explosive with high sensitivity.
基金Supported by the Construction Project of Party Branch Secretary’s Studio of "Double Leader" Teachers in Colleges and Universities of the Ministry of Education of ChinaThe Project of Party Construction Research of Yunnan University of Finance and Economics
文摘The integration and development of grass-roots Party organizations and accurate poverty alleviation is the focus in social development in the new period. This is also a new measure explored by the CPC Central Committee in the new historical period to solve rural reform and extricate the poor from poverty,and can effectively enhance the enthusiasm of the masses in poverty alleviation and development work. Xundian Hui and Yi Autonomous County is located in the mountainous area of northeast Yunnan Province. It is one of the 592 national key counties for poverty alleviation and development and one of the 38 continuous development counties in Wumeng Mountain area. Since the implementation of the accurate poverty alleviation strategy,Xundian County insists on getting rid of poverty to grasp the overall situation of county economic and social development,focus on the actual situation of the county people,and conscientiously grasp the key of industrial poverty alleviation. It regards industry as the fundamental driving force to realize poverty alleviation from " blood transfusion" to " blood creation",and innovates the model of " Party branch +" to help the poor out of poverty by industry. It has selected 187 agricultural enterprises( cooperatives,large households) to achieve full coverage of all registered poor households,and achieved remarkable results. It has realized that each poor village has one to two leading industries,and each poor household has one to two industrial income projects,having led 30 500 poor households to increase their average income by more than 1 850 yuan. The final incidence of poverty decreased from 26. 93% in 2014 to 0. 35% at the end of 2017,becoming one of the first counties in Yunnan Province to get rid of poverty. It is also the only county in Yunnan Province that has won the Antipoverty Organization Innovation Award of the State Council. Based on field research and interviews,this paper analyzes and summarizes the specific methods,main achievements,practical experience and popularization and application measures of Xundian County " Party Branch +" to promote industrial poverty alleviation,so as to provide necessary reference for accurate poverty reduction and poverty alleviation in similar mountainous areas of Yunnan Province and other provinces.
基金This research was supported by the National Key Research and Development Program of China(2016YFD0100201 and 2016YFD0100304)the Platform of National Crop Germplasm Resources of China(2016-004 and 2017-004)the Agricultural Science and Technology Innovation Program(ASTIP)of the Chinese Academy of Agricultural Sciences.
文摘Branch number(BN)is an important agronomic attribute related to the plant architecture,adaptability,and yield of soybean.To date,few studies ofBNhave been conducted to elucidate its genetic background.We aimed to localize genetic factors affecting BN using segregating populations derived fromthe high-branching cultivar‘Kennong24’(KN24)and the low-branching cultivar‘Kenfeng19’(KF19).Composite interval mapping analysis detected a QTL(qBN-1)on chromosome 6 between the SSR markers BARCSOYSSR_06_0993 and BARCSOYSSR_06_1070 using an F2 population.To fine-map qBN-1,a RIL population was developed and genotyped with 14 SSRmarkers located in the QTL region.qBN-1 was localized to a 115.67-kb interval flanked by markers BARCSOYSSR_06_1048 and BARCSOYSSR_06_1053.The QTL was further confirmed using backcross populations of size 1305(BC2F2 with KN24 as a recurrent parent)and 1712(BC3F2 with KF19 as a recurrent parent).The fine-mapping region of qBN-1 contained only two candidate genes,Glyma.06G208800 and Glyma.06G208900,whose expression patterns were investigated by qRT-PCR.Compared to Glyma.06G208800 gene expression,Glyma.06G208900 showed the highest expression of the two genes and showed a significant difference in expression between high-and low-branching genotypes in either axillary meristem or shoot apical meristem,and showed opposite expression patterns in the two tissues at V4 and R1 stages.These results identify Glyma.06G208900 as a novel candidate gene controlling BN.Taken together,the results of this study provide a foundation for cloning and functional analysis of the qBN-1 gene and for the improvement of BN bymarker-assisted selection in soybean breeding.
基金Supported by Siberian Branch of RASEducation and Science Ministry of Russian Federation (No. 01-27-SSRT, FSTP "Astron- omy", Leading scientific school 00-15-96 710/SS-477.2003.2)RFBR (02-02-39030, 03-02-16591, 03-02-16229, 03-07-90087, 03-02-3102)RFBR-SFNS (02-02-39030)Integration with the Universities: state contract (No. 10208/1173)the China- Russia Joint Research Center on Space Weather, Chinese Academy of Sciences
文摘Presented are the ideas and proposals in regards to the pooling of by RAS, SB, ISTP, and CSSAR,CAS toward coordinated usage of existing ground-based and orbiting helio-geophysical observatories, single large installations as well as creating, forecasting services and new observing facilities, in the interests of achieving a profitable activity of the China-Russia Joint Research Center on Space Weather (JRCSW).
文摘In recent decades, substantial increase in average weight of individuals has been seen in rich countries. Such changes are the result of significant changes in pattern of people’s lives. One of these issues is increasing levels in consumption of fast foods or processed foods. According to experts, the consumption of processed foods, because of having high-calories and trans-fatty acids, is fattening and harmful. In this study, the researchers after obtaining permission from the ethics committee and head of the School of Nursing, introduced themselves to nursing students then, samples were randomly selected among those who are eligible for the study. Before performing to complete the questionnaire and relevant experiments, testimonial were asked from the subjects. At the end of the study, results were suggested that, levels of Serum folate between males and females and also among married and single people were equivalent. Level of Serum folate among those students who usually have anemia in their families is significantly lower than those ones who have not anemia in their families (P = 0.003). There was a significant relationship between age and semester with levels of folate (P i.e. by increasing age and educational terms, levels of serum folate would be reduced. The level of serum folate among students who smoke is lesser than those do not (P = 0.001).
文摘Actin is a highly conserved cytoskeletal protein that is found in essentially all eukaryotic cells,which plays a paramount role in several basic functions of the organism, such as the maintenance of cellshape, cell division, cell mobility and muscle contraction. However, little is known about actin gene family inChinese amphioxus (Branchiostoma belcheri). Here we systemically analyzed the actin genes family inBranchiostoma belched and found that amphioxus contains 33 actin genes. These genes have undergoneextensive expansion through tandem duplications by phylogenetic analysis. In addition, we also providedevidence indicating that actin genes have divergent functions by specializing their EST data in both Bran-chiostoma belched and Branchiostoma florida. Our results provided an alternative explanation for the evolu-tion of actin genes, and gave new insights into their functional roles.
文摘Introduction: Sickle cell disease is a public health problem in sub-Saharan Africa. A national referral center for the management of infants and pregnant women with sickle cell disease (CPMI-NFED) was created three decades ago in Cotonou, in the south of Benin with two regional branches including that of Parakou in the North for better access of patients to specialized care. This work is a review of five years of activities in order to describe the epidemiological, clinical, hematological and evolutionary profiles of the children followed up in the said branch. Method: This was a descriptive and retrospective cross-sectional study on the medical records of children with sickle cell disease, followed up at the regional branch of CPMI-NFED in Borgou/Alibori from June 1, 2017 to May 31, 2022. The variables studied were epidemiological, clinical, biological and evolutionary. Results: A total of 101 children with sickle cell disease were included in the study, including 78 homozygous SS (77.2%) and 23 heterozygous SC (22.8%). Their mean age at inclusion was 51.2 ± 37.6 months [6 - 204]. The sex ratio was 1.4. Vaso-occlusive crises were the main diagnostic circumstances in 42.3% of homozygotes. More than half of the children (51.5%) had a regular follow-up. The average baseline level of hemoglobin (Hb) in homozygous children was 8.8 ± 1.4 g/dl [5.8 - 11.5];and the rate of Hb S varied between 61.9 and 94.7%. In heterozygous SC children, the mean baseline level of Hb was 10.7 ± 0.6 g/dl [9.7 - 11.5]. Acute complications observed during follow-up were dominated by pneumonia and vaso-occlusive crises in both phenotypes. The overall mortality was 3% and only affected homozygous patients. Conclusion: On average, three out of four children were homozygous in our cohort. The main acute complications were infectious and vaso-occlusive. The mortality only affected homozygous carriers. Specialized follow-up has contributed to improving the quality of life of children with sickle cell disease. This could be implemented on a large scale for better survival of children with sickle cell disease.
文摘How ecological environmental monitoring provides scientific and technological strength for ecological environmental management was studied.In recent years,the Ecological Environment Monitoring Station of Yanshan Branch,Wenshan Prefecture Ecological Environment Bureau,Yunnan Province has developed into a provincial environmental education base,a provincial science education base,and a national environmental protection facility open to the public by relying on monitoring equipment and facilities,personnel training,monitoring and law enforcement interaction,analysis of abnormal data,and countermeasures and suggestions were put forward for the problems in the development.
