目的:近年来,运动作为一种非药物干预手段被广泛认为可有效改善血管功能健康。此次研究系统评价不同运动方式对预防和改善超重或肥胖儿童青少年人群心血管疾病的效果。方法:在PubMed、Web of Science、Cochrane library及EBSCO-SPORTD...目的:近年来,运动作为一种非药物干预手段被广泛认为可有效改善血管功能健康。此次研究系统评价不同运动方式对预防和改善超重或肥胖儿童青少年人群心血管疾病的效果。方法:在PubMed、Web of Science、Cochrane library及EBSCO-SPORTD数据库中检索关于不同运动方式对超重或肥胖儿童青少年血管功能影响的随机对照试验文献,对照组进行常规生活,试验组进行连续的传统有氧训练、抗阻训练、传统间歇训练或联合训练,检索时限为各数据库建库至2025-02-17,由2名研究人员对所纳入的研究进行筛选、质量评价和数据提取,采用RevMan 5.4和R语言对结局指标进行贝叶斯Meta分析,包括合并效应量、亚组分析、马尔科夫链收敛性诊断以及漏斗图的绘制。结果:①最终筛选纳入符合要求的15项随机对照试验,包含767例受试者,纳入文献整体质量较高;②贝叶斯Meta分析结果显示,与对照组比较,运动干预对超重或肥胖儿童青少年脉搏波传导速度[SMD=-0.72,95%CI(-1.30,-0.15)]、血流介导的血管舒张功能[SMD=0.91,95%CI(0.38,1.40)]和颈动脉内膜中层厚度[SMD=-0.28,95%CI(-0.51,-0.06)]3项指标均具有改善效果;③亚组分析结果显示,与对照组相比,高强度间歇训练可改善超重或肥胖儿童青少年的脉搏波传导速度[SMD=-1.13,95%CI(-1.76,-0.51),P<0.05]、血流介导的血管舒张功能[SMD=0.74,95%CI(0.15,1.34),P<0.05]和颈动脉内膜中层厚度[SMD=-0.80,95%CI(-1.40,-0.20),P<0.05],有氧训练可改善超重或肥胖儿童青少年血流介导的血管舒张功能[SMD=1.37,95%CI(0.97,1.77),P<0.05]。结论:当前证据表明,运动干预对超重或肥胖儿童青少年血管功能具有显著改善效果,其中高强度间歇训练改善超重或肥胖儿童青少年血管功能健康的效果最为突出,传统有氧训练改善效果次之,建议未来通过更多研究确定适用于超重或肥胖儿童青少年最佳的运动训练处方。展开更多
This study investigated the quasi-biweekly oscillation(QBWO)of the South Asian high(SAH)center in midsummer and its possible impact on rainfall in the middle and lower reaches of the Yangtze River Basin(MLYRB),using E...This study investigated the quasi-biweekly oscillation(QBWO)of the South Asian high(SAH)center in midsummer and its possible impact on rainfall in the middle and lower reaches of the Yangtze River Basin(MLYRB),using ERA5 reanalysis data and CPC(Climate Prediction Center)Global Unified Precipitation data from 1979-2023.First,associated with the phase evolution of the QBWO of the SAH center zonally,a general systematic westward propagation of a wave train pattern along the northern margin of the SAH can be identified.Second,energy analysis indicates that this wave train pattern gains energy from the basic flow through both barotropic and baroclinic energy conversion.Compared with barotropic energy conversion,baroclinic energy conversion plays the more important role in the growth,maintenance,and propagation of the wave train pattern associated with the QBWO of the SAH center.Third,the QBWO of the SAH center leads the variation in rainfall in the MLYRB by approximately four days,and might modulate the precipitation in the MLYRB by affecting the coupling of upper-and lower-level circulation anomalies over the MLYRB.The findings of this study suggest that the QBWO of the SAH center could act as potential source of predictability of intraseasonal variation in precipitation in the MLYRB.展开更多
文摘目的:近年来,运动作为一种非药物干预手段被广泛认为可有效改善血管功能健康。此次研究系统评价不同运动方式对预防和改善超重或肥胖儿童青少年人群心血管疾病的效果。方法:在PubMed、Web of Science、Cochrane library及EBSCO-SPORTD数据库中检索关于不同运动方式对超重或肥胖儿童青少年血管功能影响的随机对照试验文献,对照组进行常规生活,试验组进行连续的传统有氧训练、抗阻训练、传统间歇训练或联合训练,检索时限为各数据库建库至2025-02-17,由2名研究人员对所纳入的研究进行筛选、质量评价和数据提取,采用RevMan 5.4和R语言对结局指标进行贝叶斯Meta分析,包括合并效应量、亚组分析、马尔科夫链收敛性诊断以及漏斗图的绘制。结果:①最终筛选纳入符合要求的15项随机对照试验,包含767例受试者,纳入文献整体质量较高;②贝叶斯Meta分析结果显示,与对照组比较,运动干预对超重或肥胖儿童青少年脉搏波传导速度[SMD=-0.72,95%CI(-1.30,-0.15)]、血流介导的血管舒张功能[SMD=0.91,95%CI(0.38,1.40)]和颈动脉内膜中层厚度[SMD=-0.28,95%CI(-0.51,-0.06)]3项指标均具有改善效果;③亚组分析结果显示,与对照组相比,高强度间歇训练可改善超重或肥胖儿童青少年的脉搏波传导速度[SMD=-1.13,95%CI(-1.76,-0.51),P<0.05]、血流介导的血管舒张功能[SMD=0.74,95%CI(0.15,1.34),P<0.05]和颈动脉内膜中层厚度[SMD=-0.80,95%CI(-1.40,-0.20),P<0.05],有氧训练可改善超重或肥胖儿童青少年血流介导的血管舒张功能[SMD=1.37,95%CI(0.97,1.77),P<0.05]。结论:当前证据表明,运动干预对超重或肥胖儿童青少年血管功能具有显著改善效果,其中高强度间歇训练改善超重或肥胖儿童青少年血管功能健康的效果最为突出,传统有氧训练改善效果次之,建议未来通过更多研究确定适用于超重或肥胖儿童青少年最佳的运动训练处方。
基金supported jointly by the National Natural Science Foundation of China(Grant No.42105039)the China Postdoctoral Science Foundation(Grant No.2024M753587)+4 种基金the Hubei Provincial Natural Science Foundation and Meteorological Innovation and development Joint Foundation of China(Grant No.2023AFD104)the Shanghai Science and Technology Development Funds(Grant No.24QB2703600)the Open Project Fund of the China Meteorological Administration Basin Heavy Rainfall Key Laboratory(Grant No.2023BHR-Y03)the Basic Research Fund of the Institute of Heavy Rain,China Meteorological Administration,Wuhan(Grant No.202314)the Open Project Fund of the Key Open Laboratory of Hydrometeorology,China Meteorological Administration(Grant No.23SWQXM018)。
文摘This study investigated the quasi-biweekly oscillation(QBWO)of the South Asian high(SAH)center in midsummer and its possible impact on rainfall in the middle and lower reaches of the Yangtze River Basin(MLYRB),using ERA5 reanalysis data and CPC(Climate Prediction Center)Global Unified Precipitation data from 1979-2023.First,associated with the phase evolution of the QBWO of the SAH center zonally,a general systematic westward propagation of a wave train pattern along the northern margin of the SAH can be identified.Second,energy analysis indicates that this wave train pattern gains energy from the basic flow through both barotropic and baroclinic energy conversion.Compared with barotropic energy conversion,baroclinic energy conversion plays the more important role in the growth,maintenance,and propagation of the wave train pattern associated with the QBWO of the SAH center.Third,the QBWO of the SAH center leads the variation in rainfall in the MLYRB by approximately four days,and might modulate the precipitation in the MLYRB by affecting the coupling of upper-and lower-level circulation anomalies over the MLYRB.The findings of this study suggest that the QBWO of the SAH center could act as potential source of predictability of intraseasonal variation in precipitation in the MLYRB.