Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injectio...Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.展开更多
Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Er...Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed展开更多
Objective:Acne scarring is more common in patients with moderate to severe acne,and various monotherapies are useful to treat acne scars,however,studies evaluating the effect of combined treatments are still insuffici...Objective:Acne scarring is more common in patients with moderate to severe acne,and various monotherapies are useful to treat acne scars,however,studies evaluating the effect of combined treatments are still insufficient.This study was aimed to assess the impact of 30.0%supramolecular salicylic acid(SSA)combined with ultra-pulse carbon dioxide(CO_(2))fractional laser therapy on facial atrophic acne scars.Methods:This retrospective study included data from patients with atrophic acne scars treated from June 2020 to June 2022 in Mylike Cosmetology Hospital of Yunnan.The patients were divided into the combination group(SSA combined with ultra-pulse CO_(2)fractional laser therapy)and the laser group(ultra-pulse CO_(2)fractional laser therapy alone)depending on the treatments received.Four treatment sessions were conducted for each group.Follow-up visits were performed every 2 months after each treatment and included assessments of theÉchelle d’Évaluation clinique des cicatrices d’acnéscore,effective rate,and visual analog scale score.Continuous data were analyzed using Student t test.Dichotomous or unordered categorical data were compared using the Chi-square(χ2)test,and ordered categorical data were compared using the Mann-Whitney U test.Results:The combination and laser groups comprised 72 and 61 patients,respectively,and there were no significant differences in sex,age,or baselineÉchelle d’Évaluation clinique des cicatrices d’acnéscore between the 2 groups.The effective rate(95.8%vs.67.2%,P<0.001)was higher and the pain scores(during and after the intervention)were lower in the combination group than in the laser group(all P<0.001).The severity of erythema,edema,and crusting was milder in the combination group(P<0.001).The proportion of highly satisfied patients was higher(73.6%vs.31.2%,P<0.001)and the Dermatology Life Quality Index showed greater improvement(0.15±0.40 vs.1.39±1.53,P<0.001)in the combination group than that in the laser group.Conclusion:The combination of ultra-pulse CO_(2)fractional laser therapy and 30.0%SSA had improved efficacy in treating facial atrophic acne scars without increasing pain or inducing serious adverse reactions.展开更多
文摘Objective To investigate the clinical effect of botulinum toxin type A injection combined with low-energy CO2 fractional laser periocular rejuvenation treatment.Methods The clinical effect of botulinum type A injection alone and botulinum type A injection combined with low-energy CO2 fractional laser was compared in 96 patients who needed to receive periocular rejuvenation treatment from April 2018 to April 2019.Results After the combined low-energy CO2 fractional laser treatment was given on the basis of botulinum toxin type A injection,the follow-up global aesthetic improvement scale(GAIS)scores of the observation group were 86.78±4.67,80.31±3.66,76.94±4.03 and 40.59±4.78.The global aesthetic improvement of the dynamic and static wrinkles was obvious.The total effective rate was 93.7%.The total satisfaction rate of the patients was 95.8%,which was higher than that of the control group(P<0.05).The clinical efficacy was significant.Conclusion The application of the combined periocular rejuvenation treatment can improve the dynamic and static wrinkles simultaneously with remarkable rejuvenation effect,increase the effective rate of treatment and enhance the patients'satisfaction.
文摘Objective To observe the effect of uitrapulse CO2 laser combined with Erbium fractional laser on treatment facial scars. Methods Total 70 cases with facial scars were treated with ultrapulse CO2 laser combined with Erbium fractional laser for 3 times with 2 ～ 3 months interval. Firstly,scar resurfacing was performed
文摘Objective:Acne scarring is more common in patients with moderate to severe acne,and various monotherapies are useful to treat acne scars,however,studies evaluating the effect of combined treatments are still insufficient.This study was aimed to assess the impact of 30.0%supramolecular salicylic acid(SSA)combined with ultra-pulse carbon dioxide(CO_(2))fractional laser therapy on facial atrophic acne scars.Methods:This retrospective study included data from patients with atrophic acne scars treated from June 2020 to June 2022 in Mylike Cosmetology Hospital of Yunnan.The patients were divided into the combination group(SSA combined with ultra-pulse CO_(2)fractional laser therapy)and the laser group(ultra-pulse CO_(2)fractional laser therapy alone)depending on the treatments received.Four treatment sessions were conducted for each group.Follow-up visits were performed every 2 months after each treatment and included assessments of theÉchelle d’Évaluation clinique des cicatrices d’acnéscore,effective rate,and visual analog scale score.Continuous data were analyzed using Student t test.Dichotomous or unordered categorical data were compared using the Chi-square(χ2)test,and ordered categorical data were compared using the Mann-Whitney U test.Results:The combination and laser groups comprised 72 and 61 patients,respectively,and there were no significant differences in sex,age,or baselineÉchelle d’Évaluation clinique des cicatrices d’acnéscore between the 2 groups.The effective rate(95.8%vs.67.2%,P<0.001)was higher and the pain scores(during and after the intervention)were lower in the combination group than in the laser group(all P<0.001).The severity of erythema,edema,and crusting was milder in the combination group(P<0.001).The proportion of highly satisfied patients was higher(73.6%vs.31.2%,P<0.001)and the Dermatology Life Quality Index showed greater improvement(0.15±0.40 vs.1.39±1.53,P<0.001)in the combination group than that in the laser group.Conclusion:The combination of ultra-pulse CO_(2)fractional laser therapy and 30.0%SSA had improved efficacy in treating facial atrophic acne scars without increasing pain or inducing serious adverse reactions.
文摘目的:探讨点阵CO_(2)激光联合短波治疗仪导入重组牛碱性成纤维细胞生长因子(Recombinant bovine basic fibroblast growth factor,rb-bFGF)凝胶修复痤疮凹陷性瘢痕的美学效果及安全性。方法:纳入2023年1月-2024年1月就诊于笔者医院的134例痤疮凹陷性瘢痕患者,根据随机数字表法将其分为对照组和观察组,各67例;对照组接受点阵CO_(2)激光治疗,观察组接受点阵CO_(2)激光联合短波治疗仪导入rb-bFGF凝胶治疗。比较两组临床疗效、皮肤生理指标、美学效果评分及不良事件。结果:观察组临床疗效率(94.03%)显著高于对照组(76.12%)(P<0.05)。在调整治疗前各皮肤生理指标后,观察组治疗后经皮水分丢失量(Transdermal water loss,TEWL)、蛋白质含量均低于对照组,皮肤角质层含水量(Water content of cuticle of skin,WCSC)高于对照组(P<0.05)。在调整治疗前美观评分量表各条目后,观察组治疗后舒适度、心理影响、社交影响、自我观感、可接受性、色素沉着、柔软度、平整度和瑕疵范围得分均高于对照组(P<0.05)。两组痤疮凹陷性瘢痕患者水肿、红斑、色素沉着等不良事件发生率比较,差异无统计学意义(11.94%vs.5.97%,P>0.05)。结论:点阵CO_(2)激光联合短波治疗仪导入rb-bFGF用于痤疮凹陷性瘢痕患者的临床疗效确切,可改善皮肤生理指标,显著提升美学效果,且安全性良好。
