Professor SHAO Jing-ming has obtained more significant effect during the clinical practice in treatment of wheezing diseases by adopting ＂three-acupoint and five-needling method＂ created by himself, and the effect h...Professor SHAO Jing-ming has obtained more significant effect during the clinical practice in treatment of wheezing diseases by adopting ＂three-acupoint and five-needling method＂ created by himself, and the effect has been widely recognized by doctors and patients. After decades of development, Shao＇s ＂three-acupoint and five-needling method＂ has become a therapy with complete theoretical system and a large number of clinical research achievements, and its application scope has been expanded. In this paper, the achievements of Shao＇s ＂three-acupoint and five-needling method＂ during clinical studies in the early, middle and current development stages and related problems were reviewed comprehensively.展开更多
目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为...目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为对照组和联合组,每组50例。两组患者均进行基础康复训练,对照组另给予三伏贴贴敷治疗,联合组在对照组治疗的基础上给予穴位针刺治疗。观察两组患者临床疗效、不良反应发生率、中医证候评分、Lysholm功能评分、Lequesnse指数,检测两组患者治疗前后血清骨钙素(bone glaprotein,BGP)、骨保护素(osteoprotegerin,OPG)、I型胶原C端肽(C-telopeptide of type I collagen,CTX-Ⅰ)、白细胞介素(interleukin,IL)-1、基质金属蛋白酶(matrix metalloproteinase,MMP)-3、肿瘤坏死因子(tumor necrosis factor,TNF)-α水平。结果:两组KOA患者治疗后中医证候评分、Lequesnse指数降低、Lysholm功能评分均优于治疗前(P<0.05),且联合组治疗后中医证候评分和Lequesnse指数低于对照组,Lysholm功能评分高于对照组,差异有统计学意义(P<0.05);联合组治疗后BGP、OPG水平高于对照组,CTX-I水平低于对照组,差异有统计学意义(P<0.05);联合组治疗后IL-1、MMP-3、TNF-α水平低于对照组,差异有统计学意义(P<0.05);联合组有效率为92.00%,对照组有效率为76.00%,联合组有效率高于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为8%,联合组不良反应发生率为4%,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:穴位针刺联合三伏贴治疗老年KOA,可调节血清炎症因子水平与骨代谢指标,降低Lequesnse指数,改善患者骨关节功能,提高患者生活质量,且不良反应发生率较低。展开更多
基金Supported by The Workstation of Affiliated Hospital of Gansu University of Chinese Medicine,Henan Shao’s Acupuncture-Moxibustion School Studio:LP0116036-Z8
文摘Professor SHAO Jing-ming has obtained more significant effect during the clinical practice in treatment of wheezing diseases by adopting ＂three-acupoint and five-needling method＂ created by himself, and the effect has been widely recognized by doctors and patients. After decades of development, Shao＇s ＂three-acupoint and five-needling method＂ has become a therapy with complete theoretical system and a large number of clinical research achievements, and its application scope has been expanded. In this paper, the achievements of Shao＇s ＂three-acupoint and five-needling method＂ during clinical studies in the early, middle and current development stages and related problems were reviewed comprehensively.
文摘目的:观察穴位针刺联合三伏贴治疗老年膝骨关节炎(knee osteoarthritis,KOA)的临床疗效及对患者血清骨代谢与Lequesnse指数的影响。方法:选取2022年7月至2023年7月江西中医药大学第二附属医院诊治的KOA患者100例,按照随机数字表法分为对照组和联合组,每组50例。两组患者均进行基础康复训练,对照组另给予三伏贴贴敷治疗,联合组在对照组治疗的基础上给予穴位针刺治疗。观察两组患者临床疗效、不良反应发生率、中医证候评分、Lysholm功能评分、Lequesnse指数,检测两组患者治疗前后血清骨钙素(bone glaprotein,BGP)、骨保护素(osteoprotegerin,OPG)、I型胶原C端肽(C-telopeptide of type I collagen,CTX-Ⅰ)、白细胞介素(interleukin,IL)-1、基质金属蛋白酶(matrix metalloproteinase,MMP)-3、肿瘤坏死因子(tumor necrosis factor,TNF)-α水平。结果:两组KOA患者治疗后中医证候评分、Lequesnse指数降低、Lysholm功能评分均优于治疗前(P<0.05),且联合组治疗后中医证候评分和Lequesnse指数低于对照组,Lysholm功能评分高于对照组,差异有统计学意义(P<0.05);联合组治疗后BGP、OPG水平高于对照组,CTX-I水平低于对照组,差异有统计学意义(P<0.05);联合组治疗后IL-1、MMP-3、TNF-α水平低于对照组,差异有统计学意义(P<0.05);联合组有效率为92.00%,对照组有效率为76.00%,联合组有效率高于对照组,差异有统计学意义(P<0.05);对照组不良反应发生率为8%,联合组不良反应发生率为4%,两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:穴位针刺联合三伏贴治疗老年KOA,可调节血清炎症因子水平与骨代谢指标,降低Lequesnse指数,改善患者骨关节功能,提高患者生活质量,且不良反应发生率较低。
