Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating th...Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating this condition.Nevertheless,considering the vast amount of research that is currently being conducted,focusing on the utilization of TCM in the management of myopia,there is an urgent requirement for a thorough and comprehensive review.The review would serve to clarify the practical applications of TCM within this specific field,and it would also aim to elucidate the underlying mechanisms that are at play,providing a deeper understanding of how TCM principles can be effectively integrated into modern medical practices.Here,some modern medical pathogenesis of myopia and appropriate TCM techniques studies are summarized in the prevention and treatment of myopia.Further,we discussed the potential mechanisms and the future research directions of TCM against myopia.Identifying these mechanisms is crucial for understanding how TCM can be effectively utilized in this context.The combination of various TCM methods or the combination of traditional Chinese and Western medicine is of great significance for the prevention and control of myopia in the future.展开更多
Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience...Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience-dependent mechanisms.The pruning process involves multiple molecular signals and a series of regulatory activities governing the“eat me”and“don't eat me”states.Under physiological conditions,the interaction between glial cells and neurons results in the clearance of unnecessary synapses,maintaining normal neural circuit functionality via synaptic pruning.Alterations in genetic and environmental factors can lead to imbalanced synaptic pruning,thus promoting the occurrence and development of autism spectrum disorder,schizophrenia,Alzheimer's disease,and other neurological disorders.In this review,we investigated the molecular mechanisms responsible for synaptic pruning during neural development.We focus on how synaptic pruning can regulate neural circuits and its association with neurological disorders.Furthermore,we discuss the application of emerging optical and imaging technologies to observe synaptic structure and function,as well as their potential for clinical translation.Our aim was to enhance our understanding of synaptic pruning during neural development,including the molecular basis underlying the regulation of synaptic function and the dynamic changes in synaptic density,and to investigate the potential role of these mechanisms in the pathophysiology of neurological diseases,thus providing a theoretical foundation for the treatment of neurological disorders.展开更多
This paper presents a high-fidelity lumpedparameter(LP)thermal model(HF-LPTM)for permanent magnet synchronous machines(PMSMs)in electric vehicle(EV)applications,where various cooling techniques are considered,includin...This paper presents a high-fidelity lumpedparameter(LP)thermal model(HF-LPTM)for permanent magnet synchronous machines(PMSMs)in electric vehicle(EV)applications,where various cooling techniques are considered,including frame forced air/liquid cooling,oil jet cooling for endwinding,and rotor shaft cooling.To address the temperature misestimation in the LP thermal modelling due to assumptions of concentrated loss input and uniform heat flows,the developed HF-LPTM introduces two compensation thermal resistances for the winding and PM components,which are analytically derived from the multi-dimensional heat transfer equations and are robust against different load/thermal conditions.As validated by the finite element analysis method and experiments,the conventional LPTMs exhibit significant winding temperature deviations,while the proposed HF-LPTM can accurately predict both the midpoint and average temperatures.The developed HFLPTM is further used to assess the effectiveness of various cooling techniques under different scenarios,i.e.,steady-state thermal states under the rated load condition,and transient temperature profiles under city,freeway,and hybrid(city+freeway)driving cycles.Results indicate that no single cooling technique can maintain both winding and PM temperatures within safety limits.The combination of frame liquid cooling and oil jet cooling for end winding can sufficiently mitigate PMSM thermal stress in EV applications.展开更多
Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of suc...Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of successful treatment and survival.However,current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue.Single-model deep learning technologies for lung cancer detection,while beneficial,cannot capture the full range of features present in medical imaging data,leading to incomplete or inaccurate detection.Furthermore,it may not be robust enough to handle the wide variability in medical images due to different imaging conditions,patient anatomy,and tumor characteristics.To overcome these disadvantages,dual-model or multi-model approaches can be employed.This research focuses on enhancing the detection of lung cancer by utilizing a combination of two learning models:a Convolutional Neural Network(CNN)for categorization and the You Only Look Once(YOLOv8)architecture for real-time identification and pinpointing of tumors.CNNs automatically learn to extract hierarchical features from raw image data,capturing patterns such as edges,textures,and complex structures that are crucial for identifying lung cancer.YOLOv8 incorporates multiscale feature extraction,enabling the detection of tumors of varying sizes and scales within a single image.This is particularly beneficial for identifying small or irregularly shaped tumors that may be challenging to detect.Furthermore,through the utilization of cutting-edge data augmentation methods,such as Deep Convolutional Generative Adversarial Networks(DCGAN),the suggested approach can handle the issue of limited data and boost the models’ability to learn from diverse and comprehensive datasets.The combined method not only improved accuracy and localization but also ensured efficient real-time processing,which is crucial for practical clinical applications.The CNN achieved an accuracy of 97.67%in classifying lung tissues into healthy and cancerous categories.The YOLOv8 model achieved an Intersection over Union(IoU)score of 0.85 for tumor localization,reflecting high precision in detecting and marking tumor boundaries within the images.Finally,the incorporation of synthetic images generated by DCGAN led to a 10%improvement in both the CNN classification accuracy and YOLOv8 detection performance.展开更多
Inflatable penile prosthesis(IPP)implantation is the gold standard treatment for patients with erectile dysfunction who are refractory to medical therapy.The standard placement of the reservoir in the space of Retzius...Inflatable penile prosthesis(IPP)implantation is the gold standard treatment for patients with erectile dysfunction who are refractory to medical therapy.The standard placement of the reservoir in the space of Retzius(SOR)may be contraindicated in patients with prior pelvic or abdominal surgery due to altered anatomy and increased risk of complications.This has led to the development of alternative ectopic reservoir placement techniques.In this narrative review,we summarize the literature on various ectopic reservoir approaches,including low and high submuscular placements,submuscular techniques with counter incisions or transfascial fixation,midline submuscular placement,subcutaneous placement,and lateral retroperitoneal approaches.We describe the surgical methods,outcomes,and complication rates associated with each technique.While most methods demonstrate low complication and revision rates,direct comparisons remain limited due to heterogeneity and lack of prospective data.This review highlights the importance of individualized technique selection based on prior surgical history,body habitus,and surgeon experience.As ectopic placement becomes more widely adopted,familiarity with multiple approaches is essential for prosthetic surgeons.展开更多
Objective:To explore the application effect and value of characteristic traditional Chinese medicine(TCM)nursing techniques in the colorectal department in clinical practice,in order to provide references for improvin...Objective:To explore the application effect and value of characteristic traditional Chinese medicine(TCM)nursing techniques in the colorectal department in clinical practice,in order to provide references for improving the nursing quality of patients and promoting their rehabilitation.Method:The colorectal department of Hospital A began to implement characteristic TCM nursing techniques in January 2023.Therefore,100 patients admitted to the colorectal department from September 2022 to December 2022 were set as the control group,and 100 patients admitted from January 2023 to April 2023 were taken as the experimental group.The experimental group adopted characteristic TCM nursing techniques,including comprehensive measures such as herbal enema therapy,TCM hip bath,acupoint massage and application,and emotional care;the control group adopted conventional Western medicine nursing methods.The application effect and value of characteristic TCM nursing techniques in the clinical practice of the colorectal department were evaluated by comparing indicators such as the frequency of use,the proportion of treated patients,the number of types,and patient satisfaction between the two groups.Result:After using the characteristic TCM nursing techniques,the recovery speed of the patients in the experimental group was significantly accelerated,and the incidence of complications was significantly reduced.Specifically,the average hospital stay of the patients in the experimental group was shortened by approximately 20%compared with the control group.At the same time,the pain score of the patients in the experimental group was also significantly lower than that of the control group.In addition,the satisfaction rate of the patients in the experimental group with the nursing service was as high as 95%,significantly higher than 80%of the control group.Conclusion:The application and practice of the characteristic TCM nursing techniques in the colorectal department have shown significant advantages in improving the recovery speed of patients and the quality of nursing services,and can be further promoted in clinical practice.展开更多
In recent years,molecular identification technology has become the predominant approach for the identification of traditional Chinese medicine.The molecular identification techniques in recent years were analyzed and ...In recent years,molecular identification technology has become the predominant approach for the identification of traditional Chinese medicine.The molecular identification techniques in recent years were analyzed and summarized in this paper,such as RAPD,ISSR,RFLP,AFLP,SNP,and DNA bar code sequence analysis techniques.By consulting Sciencedirect databases and Web of Science databases,2348 related articles were found,of which 39 were related to molecular identification techniques and traditional Chinese medicine.The application of the molecular identification techniques in four aspects was reviewed,namely the identification on the authenticity(true or false),multi-source identification and genetic diversity,producing area,and growing year discrimination of traditional Chinese medicine.展开更多
With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s ...With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s lives,they also bring new opportunities for the innovation and development of competitive cheerleading.Especially for the training of aerial techniques in competitive cheerleading,which has high requirements for accuracy,coordination,and safety,the traditional training model has problems such as empiricism and insufficient risk prediction,which directly affect the quality of training.This article discusses the application value and application countermeasures of digital twin technology in the aerial techniques of competitive cheerleading,hoping to provide some reference for relevant personnel.展开更多
BACKGROUND Gastrointestinal submucosal tumors(SMTs)mostly grew in the lumen,but also some of the lesions were extraluminal,in which the stomach was the most co-mmon site.Gastrointestinal stromal tumor account for a la...BACKGROUND Gastrointestinal submucosal tumors(SMTs)mostly grew in the lumen,but also some of the lesions were extraluminal,in which the stomach was the most co-mmon site.Gastrointestinal stromal tumor account for a large proportion of SMT.Due to the deep lesion location of gastric SMT,endoscopic submucosal dissection related techniques are difficult to operate,while endoscopic full-thickness rese-ction(EFTR)has been widely used in clinical practice because it is less invasive and can preserve the physiological structure and function of the stomach.Ho-wever,complete closure of the gastrectomy site after EFTR is critical.If the closure is incomplete,it may cause peritonitis,late perforation and other conditions,and even require further surgical intervention.Although there are currently a number of suture devices and techniques that can be used to promote closure,they have the problem of requiring additional equipment or being inconvenient to use.Although metal clips are widely used,their effectiveness depends on the size and tension of the defect.Therefore,an effective and convenient endoscopic closure technique is urgently needed to solve the closure problem of gastric SMTs after treatment.AIM To investigate the effect of combined application of the preclosure technique and dental floss traction in gastric wound closure following EFTR.METHODS In this study,the data of 94 patients treated for gastric SMTs at the Gastrointestinal Endoscopy Center of the Affiliated Union Hospital of Fujian Medical University from April 2022 to May 2023 were retrospectively analyzed.The patients were divided into a preclosure group(54 patients)and a non-preclosure group(40 patients)on the basis of the timing of wound closure with titanium clips after dental floss traction-assisted EFTR.Each patient in the preclosure group had their wounds preclosed with titanium clips after subtotal lesion resection,whereas each patient in the non-preclosure group had their wounds closed with titanium clips after total lesion resection.The lesion size,wound closure time,number of titanium clips used,incidence of postoperative complications,and postoperative hospitalization time were compared between the two groups.RESULTS The wound closure time was significantly shorter in the preclosure group than in the non-preclosure group(6.69±2.109 minutes vs 11.65±3.786 minutes,P<0.001).The number of titanium clips used was significantly lower in the preclosure group(8.93±2.231)than in the non-preclosure group(12.05±4.495)(P<0.001).There was no sig-nificant difference between the two groups in terms of the need for an indwelling gastric tube or the length of postoperative hospital stay(6.41±1.31 vs 6.13±1.06 days).For all patients in the preclosure group and the non-preclosure group,resection was completed successfully without bleeding,abdominal pain,abdominal distension,or other postoperative complications.CONCLUSION Application of the preclosure technique combined with dental floss traction can be used intraoperatively to effectively close the surgical wound in patients undergoing EFTR,reliably preventing the tumor from falling into the peritoneal cavity.展开更多
BACKGROUND Gastrointestinal surgery has disadvantages such as long operation time,extended hospitalization time,and slow postoperative recovery.However,the promotion and clinical application of the enhanced recovery a...BACKGROUND Gastrointestinal surgery has disadvantages such as long operation time,extended hospitalization time,and slow postoperative recovery.However,the promotion and clinical application of the enhanced recovery after surgery(ERAS)concept have considerably shortened the hospitalization time of gastrointestinal surgery patients and reduced reactions to surgical stress and the risk of medical complications and readmission.ERAS breaks the conventional operating mode in the field of surgery but introduces great challenges in practice.AIM To explore the application of ERAS in perioperative patients within the field of gastrointestinal surgery,with a particular focus on investigating the awareness of ERAS among healthcare professionals and the barriers to its implementation.METHODS A retrospective study of medical records of perioperative patients in the gastrointestinal surgery ward of Ningbo No.2 Hospital from March 2020 to March 2022 was conducted.According to the different nursing modes adopted by patients during the perioperative period,patients were divided into the ERAS group and the control group.The postoperative outcomes of these groups such as the time to first ambulation,the time to first intake of food,and nursing satisfaction were compared.A self-developed questionnaire was used to assess the awareness of ERAS among healthcare professionals,along with a survey identifying barriers to its implementation.RESULTS Compared with the control group,the ERAS group demonstrated superior scores across various metrics,with the exception of the readmission rate due to complications within 1 month post-discharge(P<0.05).Statistically significant differences were observed between the two groups in terms of educational background,years of service,and prior training in ERAS(P<0.05).CONCLUSION ERAS significantly reduces the time to first ambulation and first food intake for patients undergoing gastrointestinal surgery.Furthermore,the awareness of ERAS among healthcare professionals correlates with their educational background,years of experience,and prior training.ERAS plays a crucial role in expediting patient recovery,improving nursing satisfaction,and optimizing healthcare resources.展开更多
The purpose of this study was to explore the application of TCM-appropriate technology in neurogenic bladder rehabilitation nursing.Firstly,the background and contents of the study were introduced.Then,it summarizes t...The purpose of this study was to explore the application of TCM-appropriate technology in neurogenic bladder rehabilitation nursing.Firstly,the background and contents of the study were introduced.Then,it summarizes the definition and development of TCM-appropriate technology and expounds the main therapy and application of TCM-appropriate technology in the rehabilitation nursing field.Besides,the pathophysiological characteristics,rehabilitation nursing measures,and rehabilitation difficulties of the neurogenic bladder are described.Then,the application method,effect and prospect of TCM-suitable technology in rehabilitation nursing of neurogenic bladder are described.In addition,the object,method,result analysis,and conclusion of the experimental study are introduced,the main results of this study are summarized,and the future research direction is prospected.In summary,this study aims to provide effective TCM-appropriate technology for neurogenic bladder rehabilitation nursing and provide a reference for clinical practice and theoretical research in related fields.展开更多
Nitrogen oxides(NO_(x))are crucial in tropospheric photochemical ozone(O_(3))production and oxidation capacity.Currently,the widely used NO_(x)measurement technique is chemiluminescence(CL)(CL-NO_(x)),which tends to o...Nitrogen oxides(NO_(x))are crucial in tropospheric photochemical ozone(O_(3))production and oxidation capacity.Currently,the widely used NO_(x)measurement technique is chemiluminescence(CL)(CL-NO_(x)),which tends to overestimate NO_(2)due to atmospheric oxidation products of NO_(x)(i.e.,NO_(z)).We developed and characterized a NO_(x)measurement system using the cavity attenuated phase shift(CAPS)technique(CAPS-NO_(x)),which is free from interferences with nitrogen-containing species.The NO_(x)measured by the CAPS-NO_(x)and CL-NO_(x)analyzers were compared.Results show that both analyzers showed consistent measurement results for NO,but the NO_(2)measured by the CAPS-NO_(x)analyzer(NO_(2)_CAPS)was mostly lower than that measured by the CL-NO_(x)analyzer(NO_(2)_CL),which led to the deviations in O_(3)formation sensitivity regime and O_(x)(=O_(3)+NO_(2))sources(i.e.,regional background and photochemically produced O_(x))determined by the ozone production efficiencies(OPE)calculated from NO_(2)_CL and NO_(2)_CAPS.Overall,OPE_CL exceeded OPE_CAPS by 18.9%,which shifted 3 out of 13 observation days from the VOCs-limited to the transition regime when judging using OPE_CL,as compared to calculations using OPE_CAPS.During the observation period,days dominated by regional background O_(x)accounted for 46%and 62%when determined using NO_(2)_CL and NO_(2)_CAPS,respectively.These findings suggest that the use of the CL-NO_(x)analyzer tends to underestimate both the VOCs-limited regime and the regional background O_(x)dominated days.The newly built CAPS-NO_(x)analyzer here can promote the accurate measurement of NO_(2),which is meaningful for diagnosing O_(3)formation regimes and O_(x)sources.展开更多
With the increasing emphasis on personal information protection,encryption through security protocols has emerged as a critical requirement in data transmission and reception processes.Nevertheless,IoT ecosystems comp...With the increasing emphasis on personal information protection,encryption through security protocols has emerged as a critical requirement in data transmission and reception processes.Nevertheless,IoT ecosystems comprise heterogeneous networks where outdated systems coexist with the latest devices,spanning a range of devices from non-encrypted ones to fully encrypted ones.Given the limited visibility into payloads in this context,this study investigates AI-based attack detection methods that leverage encrypted traffic metadata,eliminating the need for decryption and minimizing system performance degradation—especially in light of these heterogeneous devices.Using the UNSW-NB15 and CICIoT-2023 dataset,encrypted and unencrypted traffic were categorized according to security protocol,and AI-based intrusion detection experiments were conducted for each traffic type based on metadata.To mitigate the problem of class imbalance,eight different data sampling techniques were applied.The effectiveness of these sampling techniques was then comparatively analyzed using two ensemble models and three Deep Learning(DL)models from various perspectives.The experimental results confirmed that metadata-based attack detection is feasible using only encrypted traffic.In the UNSW-NB15 dataset,the f1-score of encrypted traffic was approximately 0.98,which is 4.3%higher than that of unencrypted traffic(approximately 0.94).In addition,analysis of the encrypted traffic in the CICIoT-2023 dataset using the same method showed a significantly lower f1-score of roughly 0.43,indicating that the quality of the dataset and the preprocessing approach have a substantial impact on detection performance.Furthermore,when data sampling techniques were applied to encrypted traffic,the recall in the UNSWNB15(Encrypted)dataset improved by up to 23.0%,and in the CICIoT-2023(Encrypted)dataset by 20.26%,showing a similar level of improvement.Notably,in CICIoT-2023,f1-score and Receiver Operation Characteristic-Area Under the Curve(ROC-AUC)increased by 59.0%and 55.94%,respectively.These results suggest that data sampling can have a positive effect even in encrypted environments.However,the extent of the improvement may vary depending on data quality,model architecture,and sampling strategy.展开更多
基金supported by Healthy China initiative of Traditional Chinese Medicine(No.889042).
文摘Currently,the number of patients with myopia is increasing rapidly across the globe.Traditional Chinese medicine(TCM),with its long history and rich experience,has shown promise in effectively managing and treating this condition.Nevertheless,considering the vast amount of research that is currently being conducted,focusing on the utilization of TCM in the management of myopia,there is an urgent requirement for a thorough and comprehensive review.The review would serve to clarify the practical applications of TCM within this specific field,and it would also aim to elucidate the underlying mechanisms that are at play,providing a deeper understanding of how TCM principles can be effectively integrated into modern medical practices.Here,some modern medical pathogenesis of myopia and appropriate TCM techniques studies are summarized in the prevention and treatment of myopia.Further,we discussed the potential mechanisms and the future research directions of TCM against myopia.Identifying these mechanisms is crucial for understanding how TCM can be effectively utilized in this context.The combination of various TCM methods or the combination of traditional Chinese and Western medicine is of great significance for the prevention and control of myopia in the future.
基金supported by the National Natural Science Foundation of China,No.31760290,82160688the Key Development Areas Project of Ganzhou Science and Technology,No.2022B-SF9554(all to XL)。
文摘Synaptic pruning is a crucial process in synaptic refinement,eliminating unstable synaptic connections in neural circuits.This process is triggered and regulated primarily by spontaneous neural activity and experience-dependent mechanisms.The pruning process involves multiple molecular signals and a series of regulatory activities governing the“eat me”and“don't eat me”states.Under physiological conditions,the interaction between glial cells and neurons results in the clearance of unnecessary synapses,maintaining normal neural circuit functionality via synaptic pruning.Alterations in genetic and environmental factors can lead to imbalanced synaptic pruning,thus promoting the occurrence and development of autism spectrum disorder,schizophrenia,Alzheimer's disease,and other neurological disorders.In this review,we investigated the molecular mechanisms responsible for synaptic pruning during neural development.We focus on how synaptic pruning can regulate neural circuits and its association with neurological disorders.Furthermore,we discuss the application of emerging optical and imaging technologies to observe synaptic structure and function,as well as their potential for clinical translation.Our aim was to enhance our understanding of synaptic pruning during neural development,including the molecular basis underlying the regulation of synaptic function and the dynamic changes in synaptic density,and to investigate the potential role of these mechanisms in the pathophysiology of neurological diseases,thus providing a theoretical foundation for the treatment of neurological disorders.
文摘This paper presents a high-fidelity lumpedparameter(LP)thermal model(HF-LPTM)for permanent magnet synchronous machines(PMSMs)in electric vehicle(EV)applications,where various cooling techniques are considered,including frame forced air/liquid cooling,oil jet cooling for endwinding,and rotor shaft cooling.To address the temperature misestimation in the LP thermal modelling due to assumptions of concentrated loss input and uniform heat flows,the developed HF-LPTM introduces two compensation thermal resistances for the winding and PM components,which are analytically derived from the multi-dimensional heat transfer equations and are robust against different load/thermal conditions.As validated by the finite element analysis method and experiments,the conventional LPTMs exhibit significant winding temperature deviations,while the proposed HF-LPTM can accurately predict both the midpoint and average temperatures.The developed HFLPTM is further used to assess the effectiveness of various cooling techniques under different scenarios,i.e.,steady-state thermal states under the rated load condition,and transient temperature profiles under city,freeway,and hybrid(city+freeway)driving cycles.Results indicate that no single cooling technique can maintain both winding and PM temperatures within safety limits.The combination of frame liquid cooling and oil jet cooling for end winding can sufficiently mitigate PMSM thermal stress in EV applications.
文摘Lung cancer continues to be a leading cause of cancer-related deaths worldwide,emphasizing the critical need for improved diagnostic techniques.Early detection of lung tumors significantly increases the chances of successful treatment and survival.However,current diagnostic methods often fail to detect tumors at an early stage or to accurately pinpoint their location within the lung tissue.Single-model deep learning technologies for lung cancer detection,while beneficial,cannot capture the full range of features present in medical imaging data,leading to incomplete or inaccurate detection.Furthermore,it may not be robust enough to handle the wide variability in medical images due to different imaging conditions,patient anatomy,and tumor characteristics.To overcome these disadvantages,dual-model or multi-model approaches can be employed.This research focuses on enhancing the detection of lung cancer by utilizing a combination of two learning models:a Convolutional Neural Network(CNN)for categorization and the You Only Look Once(YOLOv8)architecture for real-time identification and pinpointing of tumors.CNNs automatically learn to extract hierarchical features from raw image data,capturing patterns such as edges,textures,and complex structures that are crucial for identifying lung cancer.YOLOv8 incorporates multiscale feature extraction,enabling the detection of tumors of varying sizes and scales within a single image.This is particularly beneficial for identifying small or irregularly shaped tumors that may be challenging to detect.Furthermore,through the utilization of cutting-edge data augmentation methods,such as Deep Convolutional Generative Adversarial Networks(DCGAN),the suggested approach can handle the issue of limited data and boost the models’ability to learn from diverse and comprehensive datasets.The combined method not only improved accuracy and localization but also ensured efficient real-time processing,which is crucial for practical clinical applications.The CNN achieved an accuracy of 97.67%in classifying lung tissues into healthy and cancerous categories.The YOLOv8 model achieved an Intersection over Union(IoU)score of 0.85 for tumor localization,reflecting high precision in detecting and marking tumor boundaries within the images.Finally,the incorporation of synthetic images generated by DCGAN led to a 10%improvement in both the CNN classification accuracy and YOLOv8 detection performance.
文摘Inflatable penile prosthesis(IPP)implantation is the gold standard treatment for patients with erectile dysfunction who are refractory to medical therapy.The standard placement of the reservoir in the space of Retzius(SOR)may be contraindicated in patients with prior pelvic or abdominal surgery due to altered anatomy and increased risk of complications.This has led to the development of alternative ectopic reservoir placement techniques.In this narrative review,we summarize the literature on various ectopic reservoir approaches,including low and high submuscular placements,submuscular techniques with counter incisions or transfascial fixation,midline submuscular placement,subcutaneous placement,and lateral retroperitoneal approaches.We describe the surgical methods,outcomes,and complication rates associated with each technique.While most methods demonstrate low complication and revision rates,direct comparisons remain limited due to heterogeneity and lack of prospective data.This review highlights the importance of individualized technique selection based on prior surgical history,body habitus,and surgeon experience.As ectopic placement becomes more widely adopted,familiarity with multiple approaches is essential for prosthetic surgeons.
文摘Objective:To explore the application effect and value of characteristic traditional Chinese medicine(TCM)nursing techniques in the colorectal department in clinical practice,in order to provide references for improving the nursing quality of patients and promoting their rehabilitation.Method:The colorectal department of Hospital A began to implement characteristic TCM nursing techniques in January 2023.Therefore,100 patients admitted to the colorectal department from September 2022 to December 2022 were set as the control group,and 100 patients admitted from January 2023 to April 2023 were taken as the experimental group.The experimental group adopted characteristic TCM nursing techniques,including comprehensive measures such as herbal enema therapy,TCM hip bath,acupoint massage and application,and emotional care;the control group adopted conventional Western medicine nursing methods.The application effect and value of characteristic TCM nursing techniques in the clinical practice of the colorectal department were evaluated by comparing indicators such as the frequency of use,the proportion of treated patients,the number of types,and patient satisfaction between the two groups.Result:After using the characteristic TCM nursing techniques,the recovery speed of the patients in the experimental group was significantly accelerated,and the incidence of complications was significantly reduced.Specifically,the average hospital stay of the patients in the experimental group was shortened by approximately 20%compared with the control group.At the same time,the pain score of the patients in the experimental group was also significantly lower than that of the control group.In addition,the satisfaction rate of the patients in the experimental group with the nursing service was as high as 95%,significantly higher than 80%of the control group.Conclusion:The application and practice of the characteristic TCM nursing techniques in the colorectal department have shown significant advantages in improving the recovery speed of patients and the quality of nursing services,and can be further promoted in clinical practice.
基金supported by National Nature Science Foundation of China(81973284)Scientific Research Foundation of the Education Department of Liaoning Province(LJKZ0944).
文摘In recent years,molecular identification technology has become the predominant approach for the identification of traditional Chinese medicine.The molecular identification techniques in recent years were analyzed and summarized in this paper,such as RAPD,ISSR,RFLP,AFLP,SNP,and DNA bar code sequence analysis techniques.By consulting Sciencedirect databases and Web of Science databases,2348 related articles were found,of which 39 were related to molecular identification techniques and traditional Chinese medicine.The application of the molecular identification techniques in four aspects was reviewed,namely the identification on the authenticity(true or false),multi-source identification and genetic diversity,producing area,and growing year discrimination of traditional Chinese medicine.
基金AI-Empowered Practical Course Teaching Project of Zhuhai College of Science and Technology(Project No.:SYSG2025025)。
文摘With the continuous development of science and technology,we have already entered the digital age.While big data,artificial intelligence,and digital twin technology provide convenience for various fields of people’s lives,they also bring new opportunities for the innovation and development of competitive cheerleading.Especially for the training of aerial techniques in competitive cheerleading,which has high requirements for accuracy,coordination,and safety,the traditional training model has problems such as empiricism and insufficient risk prediction,which directly affect the quality of training.This article discusses the application value and application countermeasures of digital twin technology in the aerial techniques of competitive cheerleading,hoping to provide some reference for relevant personnel.
文摘BACKGROUND Gastrointestinal submucosal tumors(SMTs)mostly grew in the lumen,but also some of the lesions were extraluminal,in which the stomach was the most co-mmon site.Gastrointestinal stromal tumor account for a large proportion of SMT.Due to the deep lesion location of gastric SMT,endoscopic submucosal dissection related techniques are difficult to operate,while endoscopic full-thickness rese-ction(EFTR)has been widely used in clinical practice because it is less invasive and can preserve the physiological structure and function of the stomach.Ho-wever,complete closure of the gastrectomy site after EFTR is critical.If the closure is incomplete,it may cause peritonitis,late perforation and other conditions,and even require further surgical intervention.Although there are currently a number of suture devices and techniques that can be used to promote closure,they have the problem of requiring additional equipment or being inconvenient to use.Although metal clips are widely used,their effectiveness depends on the size and tension of the defect.Therefore,an effective and convenient endoscopic closure technique is urgently needed to solve the closure problem of gastric SMTs after treatment.AIM To investigate the effect of combined application of the preclosure technique and dental floss traction in gastric wound closure following EFTR.METHODS In this study,the data of 94 patients treated for gastric SMTs at the Gastrointestinal Endoscopy Center of the Affiliated Union Hospital of Fujian Medical University from April 2022 to May 2023 were retrospectively analyzed.The patients were divided into a preclosure group(54 patients)and a non-preclosure group(40 patients)on the basis of the timing of wound closure with titanium clips after dental floss traction-assisted EFTR.Each patient in the preclosure group had their wounds preclosed with titanium clips after subtotal lesion resection,whereas each patient in the non-preclosure group had their wounds closed with titanium clips after total lesion resection.The lesion size,wound closure time,number of titanium clips used,incidence of postoperative complications,and postoperative hospitalization time were compared between the two groups.RESULTS The wound closure time was significantly shorter in the preclosure group than in the non-preclosure group(6.69±2.109 minutes vs 11.65±3.786 minutes,P<0.001).The number of titanium clips used was significantly lower in the preclosure group(8.93±2.231)than in the non-preclosure group(12.05±4.495)(P<0.001).There was no sig-nificant difference between the two groups in terms of the need for an indwelling gastric tube or the length of postoperative hospital stay(6.41±1.31 vs 6.13±1.06 days).For all patients in the preclosure group and the non-preclosure group,resection was completed successfully without bleeding,abdominal pain,abdominal distension,or other postoperative complications.CONCLUSION Application of the preclosure technique combined with dental floss traction can be used intraoperatively to effectively close the surgical wound in patients undergoing EFTR,reliably preventing the tumor from falling into the peritoneal cavity.
基金Supported by Zhejiang Province Medical and Health Science and Technology Project,No.2025KY1381。
文摘BACKGROUND Gastrointestinal surgery has disadvantages such as long operation time,extended hospitalization time,and slow postoperative recovery.However,the promotion and clinical application of the enhanced recovery after surgery(ERAS)concept have considerably shortened the hospitalization time of gastrointestinal surgery patients and reduced reactions to surgical stress and the risk of medical complications and readmission.ERAS breaks the conventional operating mode in the field of surgery but introduces great challenges in practice.AIM To explore the application of ERAS in perioperative patients within the field of gastrointestinal surgery,with a particular focus on investigating the awareness of ERAS among healthcare professionals and the barriers to its implementation.METHODS A retrospective study of medical records of perioperative patients in the gastrointestinal surgery ward of Ningbo No.2 Hospital from March 2020 to March 2022 was conducted.According to the different nursing modes adopted by patients during the perioperative period,patients were divided into the ERAS group and the control group.The postoperative outcomes of these groups such as the time to first ambulation,the time to first intake of food,and nursing satisfaction were compared.A self-developed questionnaire was used to assess the awareness of ERAS among healthcare professionals,along with a survey identifying barriers to its implementation.RESULTS Compared with the control group,the ERAS group demonstrated superior scores across various metrics,with the exception of the readmission rate due to complications within 1 month post-discharge(P<0.05).Statistically significant differences were observed between the two groups in terms of educational background,years of service,and prior training in ERAS(P<0.05).CONCLUSION ERAS significantly reduces the time to first ambulation and first food intake for patients undergoing gastrointestinal surgery.Furthermore,the awareness of ERAS among healthcare professionals correlates with their educational background,years of experience,and prior training.ERAS plays a crucial role in expediting patient recovery,improving nursing satisfaction,and optimizing healthcare resources.
文摘The purpose of this study was to explore the application of TCM-appropriate technology in neurogenic bladder rehabilitation nursing.Firstly,the background and contents of the study were introduced.Then,it summarizes the definition and development of TCM-appropriate technology and expounds the main therapy and application of TCM-appropriate technology in the rehabilitation nursing field.Besides,the pathophysiological characteristics,rehabilitation nursing measures,and rehabilitation difficulties of the neurogenic bladder are described.Then,the application method,effect and prospect of TCM-suitable technology in rehabilitation nursing of neurogenic bladder are described.In addition,the object,method,result analysis,and conclusion of the experimental study are introduced,the main results of this study are summarized,and the future research direction is prospected.In summary,this study aims to provide effective TCM-appropriate technology for neurogenic bladder rehabilitation nursing and provide a reference for clinical practice and theoretical research in related fields.
基金supported by the Natural Science Foundation of Guangdong Province(No.2020A1515110526)the Key-Area Research and Development Programof Guangdong Province(No.2020B1111360003)the National Natural Science Foundation of China(No.42305096).
文摘Nitrogen oxides(NO_(x))are crucial in tropospheric photochemical ozone(O_(3))production and oxidation capacity.Currently,the widely used NO_(x)measurement technique is chemiluminescence(CL)(CL-NO_(x)),which tends to overestimate NO_(2)due to atmospheric oxidation products of NO_(x)(i.e.,NO_(z)).We developed and characterized a NO_(x)measurement system using the cavity attenuated phase shift(CAPS)technique(CAPS-NO_(x)),which is free from interferences with nitrogen-containing species.The NO_(x)measured by the CAPS-NO_(x)and CL-NO_(x)analyzers were compared.Results show that both analyzers showed consistent measurement results for NO,but the NO_(2)measured by the CAPS-NO_(x)analyzer(NO_(2)_CAPS)was mostly lower than that measured by the CL-NO_(x)analyzer(NO_(2)_CL),which led to the deviations in O_(3)formation sensitivity regime and O_(x)(=O_(3)+NO_(2))sources(i.e.,regional background and photochemically produced O_(x))determined by the ozone production efficiencies(OPE)calculated from NO_(2)_CL and NO_(2)_CAPS.Overall,OPE_CL exceeded OPE_CAPS by 18.9%,which shifted 3 out of 13 observation days from the VOCs-limited to the transition regime when judging using OPE_CL,as compared to calculations using OPE_CAPS.During the observation period,days dominated by regional background O_(x)accounted for 46%and 62%when determined using NO_(2)_CL and NO_(2)_CAPS,respectively.These findings suggest that the use of the CL-NO_(x)analyzer tends to underestimate both the VOCs-limited regime and the regional background O_(x)dominated days.The newly built CAPS-NO_(x)analyzer here can promote the accurate measurement of NO_(2),which is meaningful for diagnosing O_(3)formation regimes and O_(x)sources.
基金supported by the Institute of Information&Communications Technology Planning&Evaluation(IITP)grant funded by the Korea government(MSIT)(No.RS-2023-00235509Development of security monitoring technology based network behavior against encrypted cyber threats in ICT convergence environment).
文摘With the increasing emphasis on personal information protection,encryption through security protocols has emerged as a critical requirement in data transmission and reception processes.Nevertheless,IoT ecosystems comprise heterogeneous networks where outdated systems coexist with the latest devices,spanning a range of devices from non-encrypted ones to fully encrypted ones.Given the limited visibility into payloads in this context,this study investigates AI-based attack detection methods that leverage encrypted traffic metadata,eliminating the need for decryption and minimizing system performance degradation—especially in light of these heterogeneous devices.Using the UNSW-NB15 and CICIoT-2023 dataset,encrypted and unencrypted traffic were categorized according to security protocol,and AI-based intrusion detection experiments were conducted for each traffic type based on metadata.To mitigate the problem of class imbalance,eight different data sampling techniques were applied.The effectiveness of these sampling techniques was then comparatively analyzed using two ensemble models and three Deep Learning(DL)models from various perspectives.The experimental results confirmed that metadata-based attack detection is feasible using only encrypted traffic.In the UNSW-NB15 dataset,the f1-score of encrypted traffic was approximately 0.98,which is 4.3%higher than that of unencrypted traffic(approximately 0.94).In addition,analysis of the encrypted traffic in the CICIoT-2023 dataset using the same method showed a significantly lower f1-score of roughly 0.43,indicating that the quality of the dataset and the preprocessing approach have a substantial impact on detection performance.Furthermore,when data sampling techniques were applied to encrypted traffic,the recall in the UNSWNB15(Encrypted)dataset improved by up to 23.0%,and in the CICIoT-2023(Encrypted)dataset by 20.26%,showing a similar level of improvement.Notably,in CICIoT-2023,f1-score and Receiver Operation Characteristic-Area Under the Curve(ROC-AUC)increased by 59.0%and 55.94%,respectively.These results suggest that data sampling can have a positive effect even in encrypted environments.However,the extent of the improvement may vary depending on data quality,model architecture,and sampling strategy.
