<strong>Introduction:</strong> The role of immunosuppression of TCD4<sup>+</sup> lymphocytes in the onset of stroke in people living with HIV has been reported in numerous studies examining the...<strong>Introduction:</strong> The role of immunosuppression of TCD4<sup>+</sup> lymphocytes in the onset of stroke in people living with HIV has been reported in numerous studies examining the co-morbidity of stroke and HIV. Objective: To determine the correlation between the viral load and the type of stroke. <strong>Methodology:</strong> This was a 7-month cross-sectional descriptive study carried out in the Neurology Department of Loandjili General Hospital in Pointe-Noire. The study population consisted of patients living with HIV who had a stroke confirmed by brain scan. The sero-immunological investigation consisted of looking for T lymphocyte typing from two kits: a CD4<sup>+</sup> T lymphocyte typing reagent kit (BD FACS Presto TM) and a GeneXpert kit for viral load (Xpert<sup><span style="color:#000000;font-family:Roboto, "white-space:normal;background-color:#D46399;">®</span></sup>HIV-1 Viral Load). The database was made from the 2010 version of Microsoft Excel. <strong>Results:</strong> We included 16 patients living with HIV, 56% of whom were women with a sex ration of 0.78. The mean age was 56.92 ± 11.21. The mean number of TCD4<sup>+</sup> lymphocytes was 413.44 ± 677.95/mm<sup>3</sup>;minimum: 93/mm<sup>3</sup>;maximum: 2854/mm<sup>3</sup>. The mean viral load was 17,996.31 ± 20,982.22/mm<sup>3</sup>;minimum: 1002/mm<sup>3</sup>;maximum: 67,229/mm<sup>3</sup>. No significant difference between the viral load and the occurrence of the stroke (p = 0.13). <strong>Conclusion:</strong> Our study did not show a causal link between viral load, immunosuppression of TCD4<sup>+</sup> lymphocytes and the onset of stroke.展开更多
<strong><span style="font-family:Verdana;">INTRODUCTION</span></strong><span><span><span style="font-family:;" "=""><span style="fon...<strong><span style="font-family:Verdana;">INTRODUCTION</span></strong><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">:</span><span style="font-family:Verdana;"> Gait asymmetry can become very pronounced in patie</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">nts who have suffered a stroke. The impairment of trunk function in some stroke patients can restrict thorax mobility and cause respiratory muscle weakness. Trunk and neck dysfunction are believed to affect the gait in stroke patients. </span><b><span style="font-family:Verdana;">OBJECTIVE</span></b><span style="font-family:Verdana;">: This study aimed to investigate the relationship between gait asymmetry and respiratory function in stroke patients by measuring the step time and trunk acceleration. </span><b><span style="font-family:Verdana;">METHODS</span></b><span style="font-family:Verdana;">: This study employed a cross-sec</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">- </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">tional design. Thirty stroke patients participated in this study. The symmetry index (SI) and Lissajous index (LI) were used to evaluate asymmetry during walking. The respiratory function and respiratory muscle strength were eva</span><span style="font-family:Verdana;">luated by spirometry. We examined the relation between SI or LI and the res</span><span style="font-family:Verdana;">piratory function/respiratory muscle strength in patients with stroke. </span><b><span style="font-family:Verdana;">RE</span></b></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">- </span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">SULTS</span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">: The results of our analysis demonstrated that the SI was significantly correlated with the inspiratory and expiratory muscle strength and the </span><span><span style="font-family:Verdana;">LI was significantly correlated with the percentage of the predicted vital capacity (respectively, r = <span style="white-space:nowrap;">﹣</span>0.386, r = <span style="white-space:nowrap;">﹣</span>0.392, r = <span style="white-space:nowrap;">﹣</span>0.446;p < 0.05). </span><b><span style="font-family:Verdana;">CONCLUSION</span></b><span style="font-family:Verdana;">: </span></span><span style="font-family:Verdana;">The present study is the first to indicate a relationship between gait asymmetry and respiratory function in stroke patients.</span></span></span></span>展开更多
文摘<strong>Introduction:</strong> The role of immunosuppression of TCD4<sup>+</sup> lymphocytes in the onset of stroke in people living with HIV has been reported in numerous studies examining the co-morbidity of stroke and HIV. Objective: To determine the correlation between the viral load and the type of stroke. <strong>Methodology:</strong> This was a 7-month cross-sectional descriptive study carried out in the Neurology Department of Loandjili General Hospital in Pointe-Noire. The study population consisted of patients living with HIV who had a stroke confirmed by brain scan. The sero-immunological investigation consisted of looking for T lymphocyte typing from two kits: a CD4<sup>+</sup> T lymphocyte typing reagent kit (BD FACS Presto TM) and a GeneXpert kit for viral load (Xpert<sup><span style="color:#000000;font-family:Roboto, "white-space:normal;background-color:#D46399;">®</span></sup>HIV-1 Viral Load). The database was made from the 2010 version of Microsoft Excel. <strong>Results:</strong> We included 16 patients living with HIV, 56% of whom were women with a sex ration of 0.78. The mean age was 56.92 ± 11.21. The mean number of TCD4<sup>+</sup> lymphocytes was 413.44 ± 677.95/mm<sup>3</sup>;minimum: 93/mm<sup>3</sup>;maximum: 2854/mm<sup>3</sup>. The mean viral load was 17,996.31 ± 20,982.22/mm<sup>3</sup>;minimum: 1002/mm<sup>3</sup>;maximum: 67,229/mm<sup>3</sup>. No significant difference between the viral load and the occurrence of the stroke (p = 0.13). <strong>Conclusion:</strong> Our study did not show a causal link between viral load, immunosuppression of TCD4<sup>+</sup> lymphocytes and the onset of stroke.
文摘<strong><span style="font-family:Verdana;">INTRODUCTION</span></strong><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">:</span><span style="font-family:Verdana;"> Gait asymmetry can become very pronounced in patie</span></span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">nts who have suffered a stroke. The impairment of trunk function in some stroke patients can restrict thorax mobility and cause respiratory muscle weakness. Trunk and neck dysfunction are believed to affect the gait in stroke patients. </span><b><span style="font-family:Verdana;">OBJECTIVE</span></b><span style="font-family:Verdana;">: This study aimed to investigate the relationship between gait asymmetry and respiratory function in stroke patients by measuring the step time and trunk acceleration. </span><b><span style="font-family:Verdana;">METHODS</span></b><span style="font-family:Verdana;">: This study employed a cross-sec</span></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">- </span></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">tional design. Thirty stroke patients participated in this study. The symmetry index (SI) and Lissajous index (LI) were used to evaluate asymmetry during walking. The respiratory function and respiratory muscle strength were eva</span><span style="font-family:Verdana;">luated by spirometry. We examined the relation between SI or LI and the res</span><span style="font-family:Verdana;">piratory function/respiratory muscle strength in patients with stroke. </span><b><span style="font-family:Verdana;">RE</span></b></span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">- </span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">SULTS</span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">: The results of our analysis demonstrated that the SI was significantly correlated with the inspiratory and expiratory muscle strength and the </span><span><span style="font-family:Verdana;">LI was significantly correlated with the percentage of the predicted vital capacity (respectively, r = <span style="white-space:nowrap;">﹣</span>0.386, r = <span style="white-space:nowrap;">﹣</span>0.392, r = <span style="white-space:nowrap;">﹣</span>0.446;p < 0.05). </span><b><span style="font-family:Verdana;">CONCLUSION</span></b><span style="font-family:Verdana;">: </span></span><span style="font-family:Verdana;">The present study is the first to indicate a relationship between gait asymmetry and respiratory function in stroke patients.</span></span></span></span>
