Under the current government strategy of building a Silk Road economic belt, tourism in Chinese border counties has becoming increasingly popular. Studying tourism competitiveness in Chinese border counties is of siza...Under the current government strategy of building a Silk Road economic belt, tourism in Chinese border counties has becoming increasingly popular. Studying tourism competitiveness in Chinese border counties is of sizable theoretical and practical importance, as there are several notable factors involved. In this study, we constructed a tourism competitiveness evaluation model based on eight factors: natural environment, tourism resource, location and transportation, social environment, tourism service facility, border port, tourism industrial cluster and tourism market. We then analyzed the spatial characteristics of tourism competitiveness in border counties and identified five types of border counties: resource advantage type(RA), border-port advantage type(PA), location advantage type(LA), agglomeration advantage type(AA), and relative balance type(RB), and examined the correlation between tourism market competitiveness and interior competitiveness factors in the counties from 2006 to 2011. Results showed that tourism resource, location and transportation, and tourism service facility are the most important competition factors for RA border counties during the study period. Competition factors in PA counties transferred from tourism resource, social environment and tourism service facility to border port and tourism industrial cluster; competition factors in LA counties transferred from natural environment and tourism resource to tourism service facility and tourism industrial cluster and border port. Competition factors in AA counties transferred from tourism service facility to tourism resource. Tourism industrial cluster, tourism service facility and tourism resource proved to be important competition factors in RB counties. The findings of this study can be used to target tourism strategies according to different county types.展开更多
Research on the spatio-temporal correlation between the intensity of human activities and the temperature of earth surfaces is of great significance in many aspects,including fully understanding the causes and mechani...Research on the spatio-temporal correlation between the intensity of human activities and the temperature of earth surfaces is of great significance in many aspects,including fully understanding the causes and mechanisms of climate change,actively adapting to climate change,pursuing rational development,and protecting the ecological environment.Taking the north slope of Tianshan Mountains,located in the arid area of northwestern China and extremely sensitive to climate change,as the research area,this study retrieves the surface temperature of the mountain based on MODIS data,while characterizing the intensity of human activities thereby data on the night light,population distribution and land use.The evolution characteristics of human activity intensity and surface temperature in the study area from 2000 to 2018 were analyzed,and the spatio-temporal correlation between them was further explored.It is found that:(1)The average human activity intensity(0.11)in the research area has kept relatively low since this century,and the overall trend has been slowly rising in a stepwise manner(0.0024·a-1);in addition,the increase in human activity intensity has lagged behind that in construction land and population by 1-2 years.(2)The annual average surface temperature in the area is 7.18℃with a pronounced growth.The rate of change(0.02℃·a-1)is about 2.33 times that of the world.The striking boost in spring(0.068℃·a-1)contributes the most to the overall warming trend.Spatially,the surface temperature is low in the south and high in the north,due to the prominent influence of the underlying surface characteristics,such as elevation and vegetation coverage.(3)The intensity of human activity and the surface temperature are remarkably positively correlated in the human activity areas there,showing a strong distribution in the east section and a weak one in the west section.The expression of its spatial differentiation and correlation is comprehensively affected by such factors as scopes of human activities,manifestations,and land-use changes.Vegetation-related human interventions,such as agriculture and forestry planting,urban greening,and afforestation,can effectively reduce the surface warming caused by human activities.This study not only puts forward new ideas to finely portray the intensity of human activities but also offers a scientific reference for regional human-land coordination and overall development.展开更多
Objective:To investigate the clinical characteristics and clinicopathological correlations of bilateral breast cancer(BBC)in China.Methods:Data of 440 patients diagnosed with BBC in 2018 were collected from 33 centers...Objective:To investigate the clinical characteristics and clinicopathological correlations of bilateral breast cancer(BBC)in China.Methods:Data of 440 patients diagnosed with BBC in 2018 were collected from 33 centers of the Chinese Society of Breast Surgery.Demographic characteristics,bilateral tumor characteristics,and comprehensive treatment data were obtained.Correlations between the clinicopathological characteristics of bilateral tumors were analyzed.Results:The proportion of BBC was 0.22%-3.08%.A total of 33(7.5%)patients had a family history of malignant tumors,304(69.1%)patients had synchronous BBC.Only 1(0.2%)patient was male.More than half of all patients received concurrent or asynchronous endocrine/chemotherapy,32.5%of all human epidermal growth factor receptor 2(HER2)-positive patients received HER2-targeted therapy,and approximately 21.6%of all patients received radiotherapy.The most common pathological cancer type was invasive ductal cancer(>60%).Approximately 70%of all patients had bilateral hormone receptor(HR)-positive tumors and presented with a single breast mass.Significant correlations were found with pathological type,histological grade,locations of tumor,molecular subtype,Ki-67 index,tumor site and size of bilateral tumors.Results of the subgroup analysis showed more clinicopathological characteristics when synchronous BBC was compared with metachronous BBC.Conclusions:In China,the clinicopathological characteristics of bilateral tumors showed significant correlations,and more significant clinicopathological correlations were observed when synchronous BBC was compared with metachronous BBC.展开更多
<strong>Objective: </strong>This study is to analyze correlation between traditional Chinese medicine (TCM) syndrome distribution characteristics and prognosis of hypertensive intracerebral hemorrhage (HIC...<strong>Objective: </strong>This study is to analyze correlation between traditional Chinese medicine (TCM) syndrome distribution characteristics and prognosis of hypertensive intracerebral hemorrhage (HICH) operation. <strong>Methods: </strong>In this study, a total of 150 patients who had received HICH operation from April, 2017 to December, 2020 in our hospital and conformed to inclusion standards were selected. According to classification of TCM syndromes, amount of bleeding of patients was recorded through multiple radiological technologies, baseline information was collected, and prognosis was investigated. The final event was long-term follow-up visit of all-cause mortalities. Moreover, correlation between prognosis and TCM syndromes was analyzed. <strong>Results:</strong> It found through investigations that there are no statistically significant differences in composition ratio of TCM syndromes among patients with different genders and different age ranges (P > 0.05). Among so many TCM syndromes, bleeding amount of patients with declining vitality and distraction is the highest, while bleeding amount of patients with stirring wind due to yin deficiency is the lowest. With respect NIHSS scores, the patients with declining vitality and distraction show the highest NIHSS scores at admission and 10 d of the course of the disease, followed by patients with upward disturbance of wind-fire. There are statistically significant differences among these two groups (P < 0.05). In this study, follow-up visits are performed to all 150 patients and the average follow-up visit time ranges within 2 - 15 months. A total of 13 deaths are reported. Number of all-cause deaths has statistically significant differences among different syndromes (P < 0.05). <strong>Conclusions:</strong> Evolutionary characteristics of TCM syndromes of HICH are manifested by development from evidence-based symptoms to deficiency syndromes. Different syndromes are correlated with prognosis of patients. On the one hand, this can be used as an objective index for TCM syndrome classification. On the other hand, this is conducive to judge prognosis recovery of patients and to apply the corresponding symptomatic treatment.展开更多
This paper comprehensively studies the spatio-temporal characteristics of the frequency of extremely heavy precipitation events over South China by using the daily precipitation data of 110 stations during 1961 to 200...This paper comprehensively studies the spatio-temporal characteristics of the frequency of extremely heavy precipitation events over South China by using the daily precipitation data of 110 stations during 1961 to 2008 and the extremely heavy precipitation thresholds determined for different stations by REOF, trend coefficients, linear trend, Mann-Kendall test and variance analysis. The results are shown as follows. The frequency distribution of extremely heavy precipitation is high in the middle of South China and low in the Guangdong coast and western Guangxi. There are three spatial distribution types of extremely heavy precipitation in South China. The consistent anomaly distribution is the main type. Distribution reversed between the east and the west and between the south and the north is also an important type. Extremely heavy precipitation events in South China mainly occurred in the summer-half of the year. Their frequency during this time accounts for 83.7% of the total frequency. In the 1960 s and 1980 s, extremely heavy precipitation events were less frequent while having an increasing trend from the late 1980 s. Their climatological tendency rates decrease in the central and rise in the other areas of South China, and on average the mean series also shows an upward but insignificant trend at all of the stations. South China's frequency of extremely heavy precipitation events can be divided into six major areas and each of them shows a different inter-annual trend and three of the representative stations experience abrupt changes by showing remarkable increases in terms of Mann-Kendall tests.展开更多
In order to identify the principal factors influencing soil water characteristics （SWC） and evaluate SWC effectively, the multivariate-statistical canonical correlation analysis （CCA） method was used to study and ...In order to identify the principal factors influencing soil water characteristics （SWC） and evaluate SWC effectively, the multivariate-statistical canonical correlation analysis （CCA） method was used to study and analyze the correlation between SWC and soil physical and chemical properties. Twenty-two soil samples were taken from 11 main tobacco-growing areas in Guizhou Province in China and the soil water characteristic curves （SWCC） and basic physical and chemical properties of the soil samples were determined. The results show that： （1） The soil bulk density, soil total porosity and soil capillary porosity have significant effects on SWC of tobacco fiels. Bulk density and total porosity are positively correlated with soil water retention characteristics （SWRC）, and soil capillary porosity is positively correlated with soil water supply characteristics （SWSC）. （2） Soil samples from different soil layers at the same soil sampling point show similarity or consistency in SWC. Inadequate soil water supply capability and imbalance between SWRC and SWSC are problems of tobacco soil. （3） The SWC of loamy clay are generally superior to those of silty clay loam.展开更多
Sludge is the by-product of wastewater treatment process. Multisource sludge can be defined as sludge from different sources. Based on the sludge properties of five typical cities in the Yangtze River basin, including...Sludge is the by-product of wastewater treatment process. Multisource sludge can be defined as sludge from different sources. Based on the sludge properties of five typical cities in the Yangtze River basin, including Jiujiang, Wuhu, Lu’an, Zhenjiang and Wuhan, this study investigated and summarized the characteristic variations and distribution differences of multiple indicators and substances from municipal sludge, dredged sludge, and river and lake sediments. The results demonstrated pH of multisource sludge was relatively stable in the neutral range. Organic matter and water content among municipal sludge were high and varied considerably between different wastewater treatment plants. Dredged sludge had an obviously higher sand content and wider particle distribution, which could be considered for graded utilization depending on its size. The nutrients composition of river and lake sediments was usually stable and special, with lower nitrogen and phosphorus content but higher potassium levels. The sources of heavy metals and persistent organic pollutants in multisource sludge were correlated, generally much higher among municipal sludge than dredged sludge and river and lake sediments, which were the most important limitation for final land utilization. Despite various properties of multisource sludge, the final fate and destination have some overall similarities, which need to be supplemented and improved by standards and laws. The study provided a preliminary analysis of suitable technical routes for municipal sludge, dredged sludge, river and lake sediments based on their different characteristics respectively, which was of great significance for multisource sludge co-treatment and disposal in the future of China.展开更多
The Multi-angle imaging spectroradiometer(MISR) land-surface(LS) bidirectional reflectance factor(BRF) product(MILS_BRF) has unique semi-simultaneous multi-angle sampling and global coverage. However, unlike on-satell...The Multi-angle imaging spectroradiometer(MISR) land-surface(LS) bidirectional reflectance factor(BRF) product(MILS_BRF) has unique semi-simultaneous multi-angle sampling and global coverage. However, unlike on-satellite observations, the spatio-temporal characteristics of MILS_BRF data have rarely been explicitly and comprehensively analysed. Results from 5-yr(2011–2015) of MILS_BRF dataset from a typical region in central Northeast Asia as the study area showed that the monthly area coverage as well as MILS_BRF data quantity varies significantly, from the highest in October(99.05%) through median in June/July(78.09%/75.21%) to lowest in January(18.97%), and a large data-vacant area exists in the study area during four consecutive winter months(December through March). The data-vacant area is mainly composed of crop lands and cropland/natural vegetation mosaic. The amount of data within the principal plane(PP)±30°(nPP) or cross PP ±30°(nCP), varies intra-annually with significant differences from different view zeniths or forward/backward scattering directions. For example, multiple off-nadir cameras have nPP but no nCP data for up to six months(September through February), with the opposite occurring in June and July. This study provides explicit and comprehensive information about the spatio-temporal characteristics of product coverage and observation geometry of MILS_BRF in the study area. Results provide required user reference information for MILS_BRF to evaluate performance of BRDF models or to compare with other satellite-derived BRF or albedo products. Comparing this final product to on-satellite observations, what was found here reveals a new perspective on product spatial coverage and observation geometry for multi-angle remote sensing.展开更多
Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFRS)in Qingdao City,China.Methods Information was collected on HFRS cases in Qingda...Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFRS)in Qingdao City,China.Methods Information was collected on HFRS cases in Qingdao City from 2010 to 2022.Descriptive epidemiologic,seasonal decomposition,spatial autocorrelation,and spatio-temporal cluster analyses were performed.Results A total of 2,220 patients with HFRS were reported over the study period,with an average annual incidence of 1.89/100,000 and a case fatality rate of 2.52%.The male:female ratio was 2.8:1.75.3%of patients were aged between 16 and 60 years old,75.3%of patients were farmers,and 11.6%had both“three red”and“three pain”symptoms.The HFRS epidemic showed two-peak seasonality:the primary fall-winter peak and the minor spring peak.The HFRS epidemic presented highly spatially heterogeneous,street/township-level hot spots that were mostly distributed in Huangdao,Pingdu,and Jiaozhou.The spatio-temporal cluster analysis revealed three cluster areas in Qingdao City that were located in the south of Huangdao District during the fall-winter peak.Conclusion The distribution of HFRS in Qingdao exhibited periodic,seasonal,and regional characteristics,with high spatial clustering heterogeneity.The typical symptoms of“three red”and“three pain”in patients with HFRS were not obvious.展开更多
Summary: In order to assess the clinical manifestations and electrocardiogram (ECG) characteristics of Chinese long QT syndrome (LQTS) patients and describe the phenotype-genotype correlation, the subjects from 5 cong...Summary: In order to assess the clinical manifestations and electrocardiogram (ECG) characteristics of Chinese long QT syndrome (LQTS) patients and describe the phenotype-genotype correlation, the subjects from 5 congenital LQTS families underwent clinical detailed examination including resting body surface ECG. QT interval and transmural dispersion of repolarization (TDR) were manually measured. Five families were genotyped by linkage analysis (polymerase chain reacting-short tandem repeat, PCR-STR). The phenotype-genotype correlation was analyzed. Four families were LQT2, 1 family was LQT3. Twenty-eight gene carriers were (14 males and 14 females) identified from 5 families. The mean QTc and TDRc were 0.56±0.04 s (range 0.42 to 0.63) and 0.16±0.04 s (range 0.09 to 0.24) respectively. 35.7 % (10/28) had normal to borderline QTc (≤ 0.460 s). There was significant difference in QTc and TDRc between the patients with symptomatic LQTS and those with asymptomatic LQTS, and there was significant difference in TDRc between the asymptomatic patients and normal people also. A history of cardiac events was present in 50 % (14/28), including 9 with syncope, 2 with sudden death (SD) and occurred in the absence of β-blocker. Three SDs occurred prior to the diagnosis of LQTS and had no ECG record. Two out of 5 SDs (40 %) occurred as the first symptom. Typical LQT2 T wave pattern were found in 40 % (6/15) of all affected members. The appearing-normal T wave was found in one LQT3 family. Low penetrance of QTc and symptoms resulted in diagnostic challenge. ECG patterns and repolarization parameters may be used to predict the genotype in most families. Genetic test is very important for identification of gene carriers.展开更多
This study reveals the temporal and spatial evolution characteristics of the winter nighttime urban heat island(UHI)effect in the case of Beijing,China.The land surface temperature(LST)is retrieved by radiative transf...This study reveals the temporal and spatial evolution characteristics of the winter nighttime urban heat island(UHI)effect in the case of Beijing,China.The land surface temperature(LST)is retrieved by radiative transfer equation by using the remote sensing data from Landsat ETM+/OLI_TIRS from 2007 to 2017 for the winter nighttime period,and LST is then divided by the mean-standard deviation method into different levels of thermal landscapes.A combination of the migration calculation of gravity center and multi-directional profile analysis is used to study the directional differentiation characteristics of LST and the migratory characteristics of the gravity center of UHI.Finally,the overall temporal and spatial evolution characteristics of winter nighttime surface urban heat island(SUHI)in Beijing are studied,and the possible reasons for the changes are discussed.Results show that Beijing's UHI effect first increased and subsequently decreased from 2007 to 2017.The winter heat island in the urban area developed from low-density agglomeration to high-density agglomeration to lowdensity diffusion.Additionally,the high-level thermal landscapes migrated to the southwest along with the city center of gravity,and the expansion rate is fastest in the southwest,which is directly linked to the changes in the urban construction land.Moreover,the overall spatial distribution of winter nighttime LST is high in the east and south and low in the west and north,and is influenced by topography,land cover,urbanization,anthropogenic heat,and other factors as well.展开更多
[Objectives]The paper was to investigate the correlation between the microscopic characteristic constants and the index component polysaccharide content of Dendrobium officinale from Guangxi.[Methods]The paraffin sect...[Objectives]The paper was to investigate the correlation between the microscopic characteristic constants and the index component polysaccharide content of Dendrobium officinale from Guangxi.[Methods]The paraffin sections of D.officinale were made,and the microscopic characteristic constants of D.officinale stem,including cross section area,vascular bundle area and phloem area,were determined by NIS-Elements D microscopic image processing software.The contents of polysaccharides in D.officinale were determined by UV-Vis spectrophotometry,and the quantitative values of microscopic characteristics of D.officinale with different growth years were analyzed by SPSS 23.0(IBM SPSS Statistics 23.0)data statistical software.The correlation between quantitative microscopic characteristics of D.officinale and its polysaccharide content was analyzed.[Results]According to the correlation between the index component of D.officinale and its quantitative microscopic characteristics,the measurement indexes,the percentage of vascular bundle in the cross section area and the percentage of hard structure in the cross section area,were strongly negatively correlated with polysaccharide content.[Conclusions]The microscopic characteristic constant values of vascular bundles of D.officinale can be used as a method to verify polysaccharide content.展开更多
Experiments were carried to determine correlations of important fruit and plant characteristics using 30 fig genotypes. The correlation coefficients between these traits were calculated using SAS program. Fruit weight...Experiments were carried to determine correlations of important fruit and plant characteristics using 30 fig genotypes. The correlation coefficients between these traits were calculated using SAS program. Fruit weight, fruit diameter, fruit length, neck length, ostiolium width, abscission of the stalk from the twig, ease of peeling, fruit skin cracks, thickness of the fruit skin, texture of skin, fruit ribs, fruit internal cavity, TSS （total soluble solids）, pH, acidity, TSS/acidity, trunk diameter, shoot length, yield per tree were traits examined in the study. According to five-year data, fruit weight was found to have positive correlation by fruit diameter （r = 0.92; P 〈 0.01）, fruit length （r = 0.81; P 〈 0.01）, neck length （r = 0.35; P 〈 0.01）, ostiolium width （r = 0.23; P 〈 0.01）, trunk diameter （r = 0.26; P 〈 0.01）, fruit skin cracks （r = 0.26; P 〈 0.01） and negative correlation by TSS （r = -0.26; P 〈 0.01） and fruit ribs （r = -0.21; P 〈 0.01）. Relations between some traits such as ostiolium width, abscission of the stalk from the twig, ease of peeling, fruit skin cracks, texture of skin and fruit ribs are deviated based on the years. Some relationships between fig fruit characteristics exist, which may help researchers to solve some problems such as ostiolium width and fruit skin cracking. These studies may contribute to producing fruit with a good quality and help to evaluate new cultivars.展开更多
Under the background of global warming, extreme cold events occur frequently. It is important to enhance the understanding of cold air patterns for forecasting cold air and reducing cold air-induced meteorological dis...Under the background of global warming, extreme cold events occur frequently. It is important to enhance the understanding of cold air patterns for forecasting cold air and reducing cold air-induced meteorological disasters. The study used the daily minimum temperatures from the National Climate Centre to classify the cold events affecting China into five different grades and the characteristics of different intensity cold events in China during the winter from 1960 to 2020 were analyzed. The results showed that there is little difference in the distribution of the frequency of general cold events from north to south, with duration longer in the north than in the south and an increase in frequency in the north in the last 60 years. The frequency of strong cold events is more in the north of China than in the south of China, and the duration is longer in the south than in the north China, with the frequency decreasing in most parts of the country. In addition to latitude, cold events frequency is closely linked to topography, with basins surrounded by high mountains being difficult to be affected by cold events, especially extreme cold events. In terms of month distribution, December was subject to the highest frequency of cold events and the longest duration of a single cold events process.展开更多
Partial discharge measurement is one of the most effective methods to find insulation defects and early failure of high voltage power equipments. The accuracy is significantly reduced by the interference in the partia...Partial discharge measurement is one of the most effective methods to find insulation defects and early failure of high voltage power equipments. The accuracy is significantly reduced by the interference in the partial discharge on-site detection or on-line monitoring, especially by the pulse interference. This paper studies the phase correlation of some types of typical partial discharge pulses and their characteristics in time domain and frequency domain. By collecting enough partial discharge pulse data, the correlation coefficient can be calculated based on both phase correlation and waveform similarity. The type of pulse will be determined by the scope of the calculated correlation coefficient. The pulses with very strong correlation will be identified as periodic pulse interference. The pulses with very weak correlation will be identified as random pulse interference. Only the pulses whose correlation coefficients fall into a specific range will be identified as partial discharge signals. In laboratory, simulated pulse interference is injected into measurement circuit, and typical partial discharge pulses are sampled by a high-speed acquisition system. The pulse interference can be effectively separated from partial discharge signals by correlation coefficient.展开更多
We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, w...We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, we identified the characteristic spectral bands that were closely related to the structure of a drug substance of interest. These characteristic spectral bands were relatively less interfered by other ingredients for analysis by the NIR correlation coefficient method. With these characteristic spectral bands, the accuracy of screening illegally added Sildenafil citrate, Tadalafil and Metforrnin hydrochloride in Chinese patent drugs and healthcare products reached about 90%, which met the requirements of rapid screening.展开更多
Objective To identify the expression of DLK1 protein in different types of renal cell carcinomas and its correlations with pathological characteristics and metastasis. Methods Immunohistochemistry analysis was perform...Objective To identify the expression of DLK1 protein in different types of renal cell carcinomas and its correlations with pathological characteristics and metastasis. Methods Immunohistochemistry analysis was performed to evaluate the expression of DLK1 protein in展开更多
Based on spatio-temporal correlativity analysis method, the automatic identification techniques for data anomaly monitoring of coal mining working face gas are presented. The asynchronous correlative characteristics o...Based on spatio-temporal correlativity analysis method, the automatic identification techniques for data anomaly monitoring of coal mining working face gas are presented. The asynchronous correlative characteristics of gas migration in working face airflow direction are qualitatively analyzed. The calculation method of asynchronous correlation delay step and the prediction and inversion formulas of gas concentration changing with time and space after gas emission in the air return roadway are provided. By calculating one hundred and fifty groups of gas sensors data series from a coal mine which have the theoretical correlativity, the correlative coefficient values range of eight kinds of data anomaly is obtained. Then the gas moni- toring data anomaly identification algorithm based on spatio-temporal correlativity analysis is accordingly presented. In order to improve the efficiency of analysis, the gas sensors code rules which can express the spatial topological relations are sug- gested. The experiments indicate that methods presented in this article can effectively compensate the defects of methods based on a single gas sensor monitoring data.展开更多
False Data Injection Attacks(FDIAs)pose a critical security threat to modern power grids,corrupting state estimation and enabling malicious control actions that can lead to severe consequences,including cascading fail...False Data Injection Attacks(FDIAs)pose a critical security threat to modern power grids,corrupting state estimation and enabling malicious control actions that can lead to severe consequences,including cascading failures,large-scale blackouts,and significant economic losses.While detecting attacks is important,accurately localizing compromised nodes or measurements is even more critical,as it enables timely mitigation,targeted response,and enhanced system resilience beyond what detection alone can offer.Existing research typically models topological features using fixed structures,which can introduce irrelevant information and affect the effectiveness of feature extraction.To address this limitation,this paper proposes an FDIA localization model with adaptive neighborhood selection,which dynamically captures spatial dependencies of the power grid by adjusting node relationships based on data-driven similarities.The improved Transformer is employed to pre-fuse global spatial features of the graph,enriching the feature representation.To improve spatio-temporal correlation extraction for FDIA localization,the proposed model employs dilated causal convolution with a gating mechanism combined with graph convolution to capture and fuse long-range temporal features and adaptive topological features.This fully exploits the temporal dynamics and spatial dependencies inherent in the power grid.Finally,multi-source information is integrated to generate highly robust node embeddings,enhancing FDIA detection and localization.Experiments are conducted on IEEE 14,57,and 118-bus systems,and the results demonstrate that the proposed model substantially improves the accuracy of FDIA localization.Additional experiments are conducted to verify the effectiveness and robustness of the proposed model.展开更多
Objective:To explore the imaging characteristics changes of pulmonary infections in patients with hypo-immunity and analyze the correlation between NLR,PCT levels and their severity.Methods:This study included 80 pati...Objective:To explore the imaging characteristics changes of pulmonary infections in patients with hypo-immunity and analyze the correlation between NLR,PCT levels and their severity.Methods:This study included 80 patients with hypo-immunity and pulmonary infections who were diagnosed and treated at our hospital from October 2022 to October 2024.Imaging examinations were performed on the patients.Subsequently,the patients were divided into a severe group and a mild group based on the severity of their disease.Univariate analysis was conducted,and variables with statistical significance from the univariate analysis were included in a multivariate logistic regression analysis to clarify the correlation between plasma NLR,PCT levels,and their severity.Results:Imaging examinations revealed that ground-glass opacities in the lungs were centered around the hilum,with patchy or map-like distributions accompanied by reticular shadows.The affected areas and normal lung areas were interspersed,with a tendency to merge.Some patients also developed pneumothorax.Ground-glass opacities were the most characteristic manifestation,which could also present as reticular shadows,interstitial thickening,miliary shadows,multiple small nodules,intrathoracic lymphadenopathy,and a small amount of pleural effusion.In the correlation analysis,NLR and PCT were statistically significant in the univariate analysis(p<0.05).When included in the multivariate logistic regression analysis,NLR(OR=2.846,95%CI:2.402-3.358)and PCT(OR=1.958,95%CI:1.554-2.601)were found to be positively correlated with the severity of pulmonary infections in patients with hypo-immunity.Conclusion:The imaging manifestations of patients with impaired immune function are complex and diverse,primarily including patchy,linear,massive,cavitary,and diffuse lesions,among other forms.These manifestations not only assist physicians in identifying the presence of pulmonary infections but also provide crucial information for diagnosing the type,severity,and complications of the infections.The levels of NLR(Neutrophil-to-Lymphocyte Ratio)and PCT(Procalcitonin)exhibit a positive correlation with the severity of pulmonary infections in patients with impaired immune function,warranting significant attention.展开更多
基金National Natural Science Foundation of China(No.41171435)
文摘Under the current government strategy of building a Silk Road economic belt, tourism in Chinese border counties has becoming increasingly popular. Studying tourism competitiveness in Chinese border counties is of sizable theoretical and practical importance, as there are several notable factors involved. In this study, we constructed a tourism competitiveness evaluation model based on eight factors: natural environment, tourism resource, location and transportation, social environment, tourism service facility, border port, tourism industrial cluster and tourism market. We then analyzed the spatial characteristics of tourism competitiveness in border counties and identified five types of border counties: resource advantage type(RA), border-port advantage type(PA), location advantage type(LA), agglomeration advantage type(AA), and relative balance type(RB), and examined the correlation between tourism market competitiveness and interior competitiveness factors in the counties from 2006 to 2011. Results showed that tourism resource, location and transportation, and tourism service facility are the most important competition factors for RA border counties during the study period. Competition factors in PA counties transferred from tourism resource, social environment and tourism service facility to border port and tourism industrial cluster; competition factors in LA counties transferred from natural environment and tourism resource to tourism service facility and tourism industrial cluster and border port. Competition factors in AA counties transferred from tourism service facility to tourism resource. Tourism industrial cluster, tourism service facility and tourism resource proved to be important competition factors in RB counties. The findings of this study can be used to target tourism strategies according to different county types.
基金National Natural Science Foundation of China(41461086)National Natural Science Foundation of China(41761108)。
文摘Research on the spatio-temporal correlation between the intensity of human activities and the temperature of earth surfaces is of great significance in many aspects,including fully understanding the causes and mechanisms of climate change,actively adapting to climate change,pursuing rational development,and protecting the ecological environment.Taking the north slope of Tianshan Mountains,located in the arid area of northwestern China and extremely sensitive to climate change,as the research area,this study retrieves the surface temperature of the mountain based on MODIS data,while characterizing the intensity of human activities thereby data on the night light,population distribution and land use.The evolution characteristics of human activity intensity and surface temperature in the study area from 2000 to 2018 were analyzed,and the spatio-temporal correlation between them was further explored.It is found that:(1)The average human activity intensity(0.11)in the research area has kept relatively low since this century,and the overall trend has been slowly rising in a stepwise manner(0.0024·a-1);in addition,the increase in human activity intensity has lagged behind that in construction land and population by 1-2 years.(2)The annual average surface temperature in the area is 7.18℃with a pronounced growth.The rate of change(0.02℃·a-1)is about 2.33 times that of the world.The striking boost in spring(0.068℃·a-1)contributes the most to the overall warming trend.Spatially,the surface temperature is low in the south and high in the north,due to the prominent influence of the underlying surface characteristics,such as elevation and vegetation coverage.(3)The intensity of human activity and the surface temperature are remarkably positively correlated in the human activity areas there,showing a strong distribution in the east section and a weak one in the west section.The expression of its spatial differentiation and correlation is comprehensively affected by such factors as scopes of human activities,manifestations,and land-use changes.Vegetation-related human interventions,such as agriculture and forestry planting,urban greening,and afforestation,can effectively reduce the surface warming caused by human activities.This study not only puts forward new ideas to finely portray the intensity of human activities but also offers a scientific reference for regional human-land coordination and overall development.
基金supported by the National Natural Science Foundation of China(No.81673762)Provincial Foundation of Liaoning(No.2019-BS-072,No.2019-ZD0780)Innovation Foundation of Dalian(No.2018J11CY026)。
文摘Objective:To investigate the clinical characteristics and clinicopathological correlations of bilateral breast cancer(BBC)in China.Methods:Data of 440 patients diagnosed with BBC in 2018 were collected from 33 centers of the Chinese Society of Breast Surgery.Demographic characteristics,bilateral tumor characteristics,and comprehensive treatment data were obtained.Correlations between the clinicopathological characteristics of bilateral tumors were analyzed.Results:The proportion of BBC was 0.22%-3.08%.A total of 33(7.5%)patients had a family history of malignant tumors,304(69.1%)patients had synchronous BBC.Only 1(0.2%)patient was male.More than half of all patients received concurrent or asynchronous endocrine/chemotherapy,32.5%of all human epidermal growth factor receptor 2(HER2)-positive patients received HER2-targeted therapy,and approximately 21.6%of all patients received radiotherapy.The most common pathological cancer type was invasive ductal cancer(>60%).Approximately 70%of all patients had bilateral hormone receptor(HR)-positive tumors and presented with a single breast mass.Significant correlations were found with pathological type,histological grade,locations of tumor,molecular subtype,Ki-67 index,tumor site and size of bilateral tumors.Results of the subgroup analysis showed more clinicopathological characteristics when synchronous BBC was compared with metachronous BBC.Conclusions:In China,the clinicopathological characteristics of bilateral tumors showed significant correlations,and more significant clinicopathological correlations were observed when synchronous BBC was compared with metachronous BBC.
文摘<strong>Objective: </strong>This study is to analyze correlation between traditional Chinese medicine (TCM) syndrome distribution characteristics and prognosis of hypertensive intracerebral hemorrhage (HICH) operation. <strong>Methods: </strong>In this study, a total of 150 patients who had received HICH operation from April, 2017 to December, 2020 in our hospital and conformed to inclusion standards were selected. According to classification of TCM syndromes, amount of bleeding of patients was recorded through multiple radiological technologies, baseline information was collected, and prognosis was investigated. The final event was long-term follow-up visit of all-cause mortalities. Moreover, correlation between prognosis and TCM syndromes was analyzed. <strong>Results:</strong> It found through investigations that there are no statistically significant differences in composition ratio of TCM syndromes among patients with different genders and different age ranges (P > 0.05). Among so many TCM syndromes, bleeding amount of patients with declining vitality and distraction is the highest, while bleeding amount of patients with stirring wind due to yin deficiency is the lowest. With respect NIHSS scores, the patients with declining vitality and distraction show the highest NIHSS scores at admission and 10 d of the course of the disease, followed by patients with upward disturbance of wind-fire. There are statistically significant differences among these two groups (P < 0.05). In this study, follow-up visits are performed to all 150 patients and the average follow-up visit time ranges within 2 - 15 months. A total of 13 deaths are reported. Number of all-cause deaths has statistically significant differences among different syndromes (P < 0.05). <strong>Conclusions:</strong> Evolutionary characteristics of TCM syndromes of HICH are manifested by development from evidence-based symptoms to deficiency syndromes. Different syndromes are correlated with prognosis of patients. On the one hand, this can be used as an objective index for TCM syndrome classification. On the other hand, this is conducive to judge prognosis recovery of patients and to apply the corresponding symptomatic treatment.
基金"Variations of Extremely Heavy Precipitation and Their Response to Global Climate Change",a project in Research Fund for the Science of Tropical Marine and Meteorology(200804)"On the Regional Extremely Heavy Rain in South China Under the Background of Climate Warming,a project in Special China Meteorological Administration Program for Climate Change(CCSF-09-03)Assessment Report on the Climate Change in the South China Region(CCSF-09-11)
文摘This paper comprehensively studies the spatio-temporal characteristics of the frequency of extremely heavy precipitation events over South China by using the daily precipitation data of 110 stations during 1961 to 2008 and the extremely heavy precipitation thresholds determined for different stations by REOF, trend coefficients, linear trend, Mann-Kendall test and variance analysis. The results are shown as follows. The frequency distribution of extremely heavy precipitation is high in the middle of South China and low in the Guangdong coast and western Guangxi. There are three spatial distribution types of extremely heavy precipitation in South China. The consistent anomaly distribution is the main type. Distribution reversed between the east and the west and between the south and the north is also an important type. Extremely heavy precipitation events in South China mainly occurred in the summer-half of the year. Their frequency during this time accounts for 83.7% of the total frequency. In the 1960 s and 1980 s, extremely heavy precipitation events were less frequent while having an increasing trend from the late 1980 s. Their climatological tendency rates decrease in the central and rise in the other areas of South China, and on average the mean series also shows an upward but insignificant trend at all of the stations. South China's frequency of extremely heavy precipitation events can be divided into six major areas and each of them shows a different inter-annual trend and three of the representative stations experience abrupt changes by showing remarkable increases in terms of Mann-Kendall tests.
基金supported by the National Key High-Tech Program (863) of China (Grant No. 2006AA10Z271)the Key Project of the Guizhou Tobacco Monopoly Administration (2007-7)
文摘In order to identify the principal factors influencing soil water characteristics （SWC） and evaluate SWC effectively, the multivariate-statistical canonical correlation analysis （CCA） method was used to study and analyze the correlation between SWC and soil physical and chemical properties. Twenty-two soil samples were taken from 11 main tobacco-growing areas in Guizhou Province in China and the soil water characteristic curves （SWCC） and basic physical and chemical properties of the soil samples were determined. The results show that： （1） The soil bulk density, soil total porosity and soil capillary porosity have significant effects on SWC of tobacco fiels. Bulk density and total porosity are positively correlated with soil water retention characteristics （SWRC）, and soil capillary porosity is positively correlated with soil water supply characteristics （SWSC）. （2） Soil samples from different soil layers at the same soil sampling point show similarity or consistency in SWC. Inadequate soil water supply capability and imbalance between SWRC and SWSC are problems of tobacco soil. （3） The SWC of loamy clay are generally superior to those of silty clay loam.
基金supported by the Scientific Research Project of China Three Gorges Corporation, China (No. 202003081)the National Key Research and Development Program of China (No. 2020YFC1908702)the National Natural Science Foundation of China (NSFC) (No. 52131002)。
文摘Sludge is the by-product of wastewater treatment process. Multisource sludge can be defined as sludge from different sources. Based on the sludge properties of five typical cities in the Yangtze River basin, including Jiujiang, Wuhu, Lu’an, Zhenjiang and Wuhan, this study investigated and summarized the characteristic variations and distribution differences of multiple indicators and substances from municipal sludge, dredged sludge, and river and lake sediments. The results demonstrated pH of multisource sludge was relatively stable in the neutral range. Organic matter and water content among municipal sludge were high and varied considerably between different wastewater treatment plants. Dredged sludge had an obviously higher sand content and wider particle distribution, which could be considered for graded utilization depending on its size. The nutrients composition of river and lake sediments was usually stable and special, with lower nitrogen and phosphorus content but higher potassium levels. The sources of heavy metals and persistent organic pollutants in multisource sludge were correlated, generally much higher among municipal sludge than dredged sludge and river and lake sediments, which were the most important limitation for final land utilization. Despite various properties of multisource sludge, the final fate and destination have some overall similarities, which need to be supplemented and improved by standards and laws. The study provided a preliminary analysis of suitable technical routes for municipal sludge, dredged sludge, river and lake sediments based on their different characteristics respectively, which was of great significance for multisource sludge co-treatment and disposal in the future of China.
基金Under the auspices the Fundamental Research Funds for the Central Universities,China(No.2017TD-26)the Plan for Changbai Mountain Scholars of Jilin Province,China(No.JJLZ[2015]54)
文摘The Multi-angle imaging spectroradiometer(MISR) land-surface(LS) bidirectional reflectance factor(BRF) product(MILS_BRF) has unique semi-simultaneous multi-angle sampling and global coverage. However, unlike on-satellite observations, the spatio-temporal characteristics of MILS_BRF data have rarely been explicitly and comprehensively analysed. Results from 5-yr(2011–2015) of MILS_BRF dataset from a typical region in central Northeast Asia as the study area showed that the monthly area coverage as well as MILS_BRF data quantity varies significantly, from the highest in October(99.05%) through median in June/July(78.09%/75.21%) to lowest in January(18.97%), and a large data-vacant area exists in the study area during four consecutive winter months(December through March). The data-vacant area is mainly composed of crop lands and cropland/natural vegetation mosaic. The amount of data within the principal plane(PP)±30°(nPP) or cross PP ±30°(nCP), varies intra-annually with significant differences from different view zeniths or forward/backward scattering directions. For example, multiple off-nadir cameras have nPP but no nCP data for up to six months(September through February), with the opposite occurring in June and July. This study provides explicit and comprehensive information about the spatio-temporal characteristics of product coverage and observation geometry of MILS_BRF in the study area. Results provide required user reference information for MILS_BRF to evaluate performance of BRDF models or to compare with other satellite-derived BRF or albedo products. Comparing this final product to on-satellite observations, what was found here reveals a new perspective on product spatial coverage and observation geometry for multi-angle remote sensing.
基金supported by the Chinese Field Epidemiology Training Program,the Research and Development of Standards and Standardization of Nomenclature in the Field of Public Health-Research Project on the Development of the Disciplines of Public Health and Preventive Medicine[242402]the Shandong Medical and Health Science and Technology Development Plan[202112050731].
文摘Objective This study investigated the epidemic characteristics and spatio-temporal dynamics of hemorrhagic fever with renal syndrome(HFRS)in Qingdao City,China.Methods Information was collected on HFRS cases in Qingdao City from 2010 to 2022.Descriptive epidemiologic,seasonal decomposition,spatial autocorrelation,and spatio-temporal cluster analyses were performed.Results A total of 2,220 patients with HFRS were reported over the study period,with an average annual incidence of 1.89/100,000 and a case fatality rate of 2.52%.The male:female ratio was 2.8:1.75.3%of patients were aged between 16 and 60 years old,75.3%of patients were farmers,and 11.6%had both“three red”and“three pain”symptoms.The HFRS epidemic showed two-peak seasonality:the primary fall-winter peak and the minor spring peak.The HFRS epidemic presented highly spatially heterogeneous,street/township-level hot spots that were mostly distributed in Huangdao,Pingdu,and Jiaozhou.The spatio-temporal cluster analysis revealed three cluster areas in Qingdao City that were located in the south of Huangdao District during the fall-winter peak.Conclusion The distribution of HFRS in Qingdao exhibited periodic,seasonal,and regional characteristics,with high spatial clustering heterogeneity.The typical symptoms of“three red”and“three pain”in patients with HFRS were not obvious.
文摘Summary: In order to assess the clinical manifestations and electrocardiogram (ECG) characteristics of Chinese long QT syndrome (LQTS) patients and describe the phenotype-genotype correlation, the subjects from 5 congenital LQTS families underwent clinical detailed examination including resting body surface ECG. QT interval and transmural dispersion of repolarization (TDR) were manually measured. Five families were genotyped by linkage analysis (polymerase chain reacting-short tandem repeat, PCR-STR). The phenotype-genotype correlation was analyzed. Four families were LQT2, 1 family was LQT3. Twenty-eight gene carriers were (14 males and 14 females) identified from 5 families. The mean QTc and TDRc were 0.56±0.04 s (range 0.42 to 0.63) and 0.16±0.04 s (range 0.09 to 0.24) respectively. 35.7 % (10/28) had normal to borderline QTc (≤ 0.460 s). There was significant difference in QTc and TDRc between the patients with symptomatic LQTS and those with asymptomatic LQTS, and there was significant difference in TDRc between the asymptomatic patients and normal people also. A history of cardiac events was present in 50 % (14/28), including 9 with syncope, 2 with sudden death (SD) and occurred in the absence of β-blocker. Three SDs occurred prior to the diagnosis of LQTS and had no ECG record. Two out of 5 SDs (40 %) occurred as the first symptom. Typical LQT2 T wave pattern were found in 40 % (6/15) of all affected members. The appearing-normal T wave was found in one LQT3 family. Low penetrance of QTc and symptoms resulted in diagnostic challenge. ECG patterns and repolarization parameters may be used to predict the genotype in most families. Genetic test is very important for identification of gene carriers.
基金supported by the Fund of National Key Laboratory of Science and Technology on Remote Sensing Information and imagery Analysis,Beijing Research Institute of Uranium Geology(No.6142A01210404)。
文摘This study reveals the temporal and spatial evolution characteristics of the winter nighttime urban heat island(UHI)effect in the case of Beijing,China.The land surface temperature(LST)is retrieved by radiative transfer equation by using the remote sensing data from Landsat ETM+/OLI_TIRS from 2007 to 2017 for the winter nighttime period,and LST is then divided by the mean-standard deviation method into different levels of thermal landscapes.A combination of the migration calculation of gravity center and multi-directional profile analysis is used to study the directional differentiation characteristics of LST and the migratory characteristics of the gravity center of UHI.Finally,the overall temporal and spatial evolution characteristics of winter nighttime surface urban heat island(SUHI)in Beijing are studied,and the possible reasons for the changes are discussed.Results show that Beijing's UHI effect first increased and subsequently decreased from 2007 to 2017.The winter heat island in the urban area developed from low-density agglomeration to high-density agglomeration to lowdensity diffusion.Additionally,the high-level thermal landscapes migrated to the southwest along with the city center of gravity,and the expansion rate is fastest in the southwest,which is directly linked to the changes in the urban construction land.Moreover,the overall spatial distribution of winter nighttime LST is high in the east and south and low in the west and north,and is influenced by topography,land cover,urbanization,anthropogenic heat,and other factors as well.
基金Supported by 2020 Operation Subsidy Project of Guangxi Key Research Laboratory of Zhuang&Yao Medicine(20-065-14)"Quantification of Microscopic Characteristics of Dendrobium officinale from Guangxi and Its Correlation with the Quality of Medicinal Materials"(GXZYYKF2020A-13)2011 Guangxi Collaborative Innovation Center"Pharmaceutical Collaborative Innovation Center of Zhuang&Yao Medicine"(GJKY[2013]20)+6 种基金Guangxi Engineering Research Center for Resources and Application of Ethnic Medicine(GFGGJH[2020]2605)National Natural Science Foundation of China(82060695)Joint Research Laboratory of Zhuang&Yao Medicine of Guangxi University of Traditional Chinese Medicine and Central South University(GKJZ[2021]238)Guangxi Science and Technology Base and Talent Project(GK AD19245090)2018 Research Start-up Fund Project of Guangxi University of Chinese Medicine for Introduced Doctors(2018BS019)2019 Basic Scientific Research Ability Improvement Project for Young and Middle-aged Teachers in Colleges and Universities in Guangxi(2019KY0310)2019-2021 Guangxi First-class Discipline Construction Open Project of Guangxi University of Traditional Chinese Medicine(2019XK101)。
文摘[Objectives]The paper was to investigate the correlation between the microscopic characteristic constants and the index component polysaccharide content of Dendrobium officinale from Guangxi.[Methods]The paraffin sections of D.officinale were made,and the microscopic characteristic constants of D.officinale stem,including cross section area,vascular bundle area and phloem area,were determined by NIS-Elements D microscopic image processing software.The contents of polysaccharides in D.officinale were determined by UV-Vis spectrophotometry,and the quantitative values of microscopic characteristics of D.officinale with different growth years were analyzed by SPSS 23.0(IBM SPSS Statistics 23.0)data statistical software.The correlation between quantitative microscopic characteristics of D.officinale and its polysaccharide content was analyzed.[Results]According to the correlation between the index component of D.officinale and its quantitative microscopic characteristics,the measurement indexes,the percentage of vascular bundle in the cross section area and the percentage of hard structure in the cross section area,were strongly negatively correlated with polysaccharide content.[Conclusions]The microscopic characteristic constant values of vascular bundles of D.officinale can be used as a method to verify polysaccharide content.
文摘Experiments were carried to determine correlations of important fruit and plant characteristics using 30 fig genotypes. The correlation coefficients between these traits were calculated using SAS program. Fruit weight, fruit diameter, fruit length, neck length, ostiolium width, abscission of the stalk from the twig, ease of peeling, fruit skin cracks, thickness of the fruit skin, texture of skin, fruit ribs, fruit internal cavity, TSS （total soluble solids）, pH, acidity, TSS/acidity, trunk diameter, shoot length, yield per tree were traits examined in the study. According to five-year data, fruit weight was found to have positive correlation by fruit diameter （r = 0.92; P 〈 0.01）, fruit length （r = 0.81; P 〈 0.01）, neck length （r = 0.35; P 〈 0.01）, ostiolium width （r = 0.23; P 〈 0.01）, trunk diameter （r = 0.26; P 〈 0.01）, fruit skin cracks （r = 0.26; P 〈 0.01） and negative correlation by TSS （r = -0.26; P 〈 0.01） and fruit ribs （r = -0.21; P 〈 0.01）. Relations between some traits such as ostiolium width, abscission of the stalk from the twig, ease of peeling, fruit skin cracks, texture of skin and fruit ribs are deviated based on the years. Some relationships between fig fruit characteristics exist, which may help researchers to solve some problems such as ostiolium width and fruit skin cracking. These studies may contribute to producing fruit with a good quality and help to evaluate new cultivars.
文摘Under the background of global warming, extreme cold events occur frequently. It is important to enhance the understanding of cold air patterns for forecasting cold air and reducing cold air-induced meteorological disasters. The study used the daily minimum temperatures from the National Climate Centre to classify the cold events affecting China into five different grades and the characteristics of different intensity cold events in China during the winter from 1960 to 2020 were analyzed. The results showed that there is little difference in the distribution of the frequency of general cold events from north to south, with duration longer in the north than in the south and an increase in frequency in the north in the last 60 years. The frequency of strong cold events is more in the north of China than in the south of China, and the duration is longer in the south than in the north China, with the frequency decreasing in most parts of the country. In addition to latitude, cold events frequency is closely linked to topography, with basins surrounded by high mountains being difficult to be affected by cold events, especially extreme cold events. In terms of month distribution, December was subject to the highest frequency of cold events and the longest duration of a single cold events process.
文摘Partial discharge measurement is one of the most effective methods to find insulation defects and early failure of high voltage power equipments. The accuracy is significantly reduced by the interference in the partial discharge on-site detection or on-line monitoring, especially by the pulse interference. This paper studies the phase correlation of some types of typical partial discharge pulses and their characteristics in time domain and frequency domain. By collecting enough partial discharge pulse data, the correlation coefficient can be calculated based on both phase correlation and waveform similarity. The type of pulse will be determined by the scope of the calculated correlation coefficient. The pulses with very strong correlation will be identified as periodic pulse interference. The pulses with very weak correlation will be identified as random pulse interference. Only the pulses whose correlation coefficients fall into a specific range will be identified as partial discharge signals. In laboratory, simulated pulse interference is injected into measurement circuit, and typical partial discharge pulses are sampled by a high-speed acquisition system. The pulse interference can be effectively separated from partial discharge signals by correlation coefficient.
基金National Key Technology R & D Program-On-site Rapid Identification of Drug Research Project (Grant No. 2008BAI55B06)
文摘We analyzed the infrared 0R）-near infrared （NIR） 2D correlation spectra of drugs perturbed by temperature. By identification of functional groups by IR spectrum and by the correlation analysis of IR-NIR spectrum, we identified the characteristic spectral bands that were closely related to the structure of a drug substance of interest. These characteristic spectral bands were relatively less interfered by other ingredients for analysis by the NIR correlation coefficient method. With these characteristic spectral bands, the accuracy of screening illegally added Sildenafil citrate, Tadalafil and Metforrnin hydrochloride in Chinese patent drugs and healthcare products reached about 90%, which met the requirements of rapid screening.
文摘Objective To identify the expression of DLK1 protein in different types of renal cell carcinomas and its correlations with pathological characteristics and metastasis. Methods Immunohistochemistry analysis was performed to evaluate the expression of DLK1 protein in
基金Supported by the National Natural Science Foundation of China （40971275, 50811120111）
文摘Based on spatio-temporal correlativity analysis method, the automatic identification techniques for data anomaly monitoring of coal mining working face gas are presented. The asynchronous correlative characteristics of gas migration in working face airflow direction are qualitatively analyzed. The calculation method of asynchronous correlation delay step and the prediction and inversion formulas of gas concentration changing with time and space after gas emission in the air return roadway are provided. By calculating one hundred and fifty groups of gas sensors data series from a coal mine which have the theoretical correlativity, the correlative coefficient values range of eight kinds of data anomaly is obtained. Then the gas moni- toring data anomaly identification algorithm based on spatio-temporal correlativity analysis is accordingly presented. In order to improve the efficiency of analysis, the gas sensors code rules which can express the spatial topological relations are sug- gested. The experiments indicate that methods presented in this article can effectively compensate the defects of methods based on a single gas sensor monitoring data.
基金supported by National Key Research and Development Plan of China(No.2022YFB3103304).
文摘False Data Injection Attacks(FDIAs)pose a critical security threat to modern power grids,corrupting state estimation and enabling malicious control actions that can lead to severe consequences,including cascading failures,large-scale blackouts,and significant economic losses.While detecting attacks is important,accurately localizing compromised nodes or measurements is even more critical,as it enables timely mitigation,targeted response,and enhanced system resilience beyond what detection alone can offer.Existing research typically models topological features using fixed structures,which can introduce irrelevant information and affect the effectiveness of feature extraction.To address this limitation,this paper proposes an FDIA localization model with adaptive neighborhood selection,which dynamically captures spatial dependencies of the power grid by adjusting node relationships based on data-driven similarities.The improved Transformer is employed to pre-fuse global spatial features of the graph,enriching the feature representation.To improve spatio-temporal correlation extraction for FDIA localization,the proposed model employs dilated causal convolution with a gating mechanism combined with graph convolution to capture and fuse long-range temporal features and adaptive topological features.This fully exploits the temporal dynamics and spatial dependencies inherent in the power grid.Finally,multi-source information is integrated to generate highly robust node embeddings,enhancing FDIA detection and localization.Experiments are conducted on IEEE 14,57,and 118-bus systems,and the results demonstrate that the proposed model substantially improves the accuracy of FDIA localization.Additional experiments are conducted to verify the effectiveness and robustness of the proposed model.
基金Pathogen Distribution,Imaging Features,and Clinical Manifestations of Pulmonary Infections in Patients with Impaired Immune Function(Project No.:2023-1-NS-017)。
文摘Objective:To explore the imaging characteristics changes of pulmonary infections in patients with hypo-immunity and analyze the correlation between NLR,PCT levels and their severity.Methods:This study included 80 patients with hypo-immunity and pulmonary infections who were diagnosed and treated at our hospital from October 2022 to October 2024.Imaging examinations were performed on the patients.Subsequently,the patients were divided into a severe group and a mild group based on the severity of their disease.Univariate analysis was conducted,and variables with statistical significance from the univariate analysis were included in a multivariate logistic regression analysis to clarify the correlation between plasma NLR,PCT levels,and their severity.Results:Imaging examinations revealed that ground-glass opacities in the lungs were centered around the hilum,with patchy or map-like distributions accompanied by reticular shadows.The affected areas and normal lung areas were interspersed,with a tendency to merge.Some patients also developed pneumothorax.Ground-glass opacities were the most characteristic manifestation,which could also present as reticular shadows,interstitial thickening,miliary shadows,multiple small nodules,intrathoracic lymphadenopathy,and a small amount of pleural effusion.In the correlation analysis,NLR and PCT were statistically significant in the univariate analysis(p<0.05).When included in the multivariate logistic regression analysis,NLR(OR=2.846,95%CI:2.402-3.358)and PCT(OR=1.958,95%CI:1.554-2.601)were found to be positively correlated with the severity of pulmonary infections in patients with hypo-immunity.Conclusion:The imaging manifestations of patients with impaired immune function are complex and diverse,primarily including patchy,linear,massive,cavitary,and diffuse lesions,among other forms.These manifestations not only assist physicians in identifying the presence of pulmonary infections but also provide crucial information for diagnosing the type,severity,and complications of the infections.The levels of NLR(Neutrophil-to-Lymphocyte Ratio)and PCT(Procalcitonin)exhibit a positive correlation with the severity of pulmonary infections in patients with impaired immune function,warranting significant attention.
