With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenu...With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenues for digital transformation and intelligent upgrading.Industry 5.0,a further extension and development of Industry 4.0,has become an important development trend in industry with more emphasis on human-centered sustainability and flexibility.Accordingly,both the industrial metaverse and digital twins have attracted much attention in this new era.However,the relationship between them is not clear enough.In this paper,a comparison between digital twins and the metaverse in industry is made firstly.Then,we propose the concept and framework of Digital Twin Systems Engineering(DTSE)to demonstrate how digital twins support the industrial metaverse in the era of Industry 5.0 by integrating systems engineering principles.Furthermore,we discuss the key technologies and challenges of DTSE,in particular how artificial intelligence enhances the application of DTSE.Finally,a specific application scenario in the aviation field is presented to illustrate the application prospects of DTSE.展开更多
Background Organic selenium(Se)has gained recognition in poultry nutrition as a feed additive to boost production and Se deposition in eggs and tissues,owing to its high bioavailability,efficient tissue accumulation a...Background Organic selenium(Se)has gained recognition in poultry nutrition as a feed additive to boost production and Se deposition in eggs and tissues,owing to its high bioavailability,efficient tissue accumulation and minimal toxicity.Selenium-enriched yeast(SeY)is a well-established source,while selenium-enriched lactobacilli(SeL),a newer alternative,offers the added benefits of probiotics.This study examined the effects of SeY and SeL on egg quality,antioxidant capacity,Se deposition,and gut health in laying hens.After a two-week pre-treatment with a Sedeficient diet(SeD),450 Hy-Line Brown laying hens(30-week-old)were assigned into five dietary groups with six replicates of 15 hens each.The groups included a SeD,SeD supplemented with 1.5 mg Se/kg from SeY(SeY15),or 1.5,3.0,and 6.0 mg Se/kg from SeL(SeL15,SeL30,SeL60).The feeding trial lasted for 12 weeks.Results SeY15 and SeL15 improved the feed-to-egg ratio(P<0.05)in the latter stages.Haugh units were significantly increased(P<0.05)in the SeY15 and SeL30 groups,while darker yolk color(P<0.05)was observed in the SeY15,SeL15,and SeL60 groups.All Se-supplemented diets increased Se content in whole eggs,albumen,and yolk(P<0.05),while SeL groups showed a dose-dependent effect.Antioxidant enzyme activities increased,and MDA content decreased in the serum(P<0.05),with SeY15 showing the highest GSH-Px levels(P<0.05).SeL60 increased serum alkaline phosphatase and aspartate transaminase,and distorted the liver architecture(P<0.05).Se-diets reduced concentrations of reactive oxygen species(ROS)in the ileum and liver(P<0.05).SeL15 improved the ileal villus height-tocrypt depth ratio(P<0.05).SeY15 and/or SeL15 up-regulated TXNRD1 and SEPHS1 mRNA while down-regulating SCLY expression in the liver.SeY15 altered ileal microbiota by increasing both beneficial and pathogenic bacteria,whereas SeL15 predominantly boosted beneficial bacteria.Conclusion SeL integrates the antioxidant properties of organic Se with the probiotic benefits on gut health,resulting in a performance-enhancing effect comparable to that of SeY.However,high SeL level(6.0 mg Se/kg)compromised productivity and metabolic functions while enhancing Se deposition.展开更多
Based on the requirements of local high-quality economic development and addressing the critical task of transformation and upgrading in the tea industry,this paper systematically discusses the necessity and feasibili...Based on the requirements of local high-quality economic development and addressing the critical task of transformation and upgrading in the tea industry,this paper systematically discusses the necessity and feasibility of constructing an optimal industrialization operation system driven by the dual wheels of"branding+standardization".The article first clarifies the connotation of high-quality development and the synergistic mechanism between branding and standardization.It then analyzes the current situation and bottlenecks of China's tea industry development.Subsequently,it proposes a dual-wheel drive strategy where branding enhances value and standardization guarantees quality,and designs a systematic implementation plan involving industrial chain synergy optimization and integrated support from government,industry,academia,research,and application.On this basis,strategies and suggestions are proposed,encompassing the starting point,standard focal points,key effort areas,innovation points,and target achievement points.The aim is to promote the tea industry to break through homogeneous competition,achieve value ascent,and provide important industrial support for regional high-quality development through the construction of the aforementioned system.展开更多
The rapid evolution of industrial robots from automation tools to intelligent systems marks a pivotal shift in manufacturing practices within the framework of Industry 4.0.Industrial robots,once limited to repetitive ...The rapid evolution of industrial robots from automation tools to intelligent systems marks a pivotal shift in manufacturing practices within the framework of Industry 4.0.Industrial robots,once limited to repetitive tasks on assembly lines,are now increasingly powered by advanced technologies such as Artificial Intelligence(AI),machine learning,and the Internet of Things(IoT),enabling them to perform complex,adaptive tasks in real-time.This paper explores the technological advancements that have transformed industrial robots,highlighting the integration of AI,smart sensors,and autonomous systems.Furthermore,it examines the implications of this paradigm shift for industries,human-robot collaboration,and the workforce.While intelligent robots promise greater efficiency,flexibility,and safety in manufacturing,challenges regarding implementation,economic impact,and ethical considerations remain significant.The paper concludes by looking at the future trends in robotics and their potential to reshape the global industrial landscape.展开更多
The“government-industry-university-research”model has significant practical significance in promoting the development of industries in colleges and universities and improving the quality of talent cultivation.This p...The“government-industry-university-research”model has significant practical significance in promoting the development of industries in colleges and universities and improving the quality of talent cultivation.This paper first provides a brief explanation of the concept and significance of the“government-industry-university-research”model,then conducts an in-depth analysis of the problems faced by the development of university industries,and finally proposes effective solutions to the problems faced by the development of university industries,hoping to provide some references and lessons for promoting the continuous development of university industries and the integration of industry and education.展开更多
Extraction unit operation is the first step in traditional Chinese medicine(TCM)product manufacturing,and it is crucial in determining the quality of the produced medicine.However,due to a lack of effective multimodal...Extraction unit operation is the first step in traditional Chinese medicine(TCM)product manufacturing,and it is crucial in determining the quality of the produced medicine.However,due to a lack of effective multimodal monitoring and adjustment strategies,achieving high quality and efficiency remains a challenge.In this work,we proposed an artificial intelligence(AI)-based robot platform for the multi-objective optimization of the extraction process.First,a perception intelligence method for multimodal process monitoring was established to track active ingredient transfer and production changes during the extraction process.Second,a digital twin model was developed to reconstruct the field information,which interacted with real-time monitoring data.Furthermore,the model performed real-time inference to predict future production process states by using the reconstructing information.Finally,according to the predicted process states,the autonomous decision-making robot implemented multi-objective optimization,ensuring efficient process adjustments for global optimization.Experimental and industrial results demonstrated that the platform could effectively infer component transfer dynamics,monitor temperature variations,and identify boiling states,ensuring product quality while reducing energy consumption.This pharmaceutical robot could promote the integration of AI and pharmaceutical engineering,thereby accelerating the iterative development and improvement of China’s pharmaceutical industry.展开更多
Objective To empirically analyze the relationship between Government R&D funding and R&D investment of the enterprises in different sub industries of pharmaceutical industry,and to provide reference for the de...Objective To empirically analyze the relationship between Government R&D funding and R&D investment of the enterprises in different sub industries of pharmaceutical industry,and to provide reference for the development of policies related to R&D funding input.Methods Granger causality test was performed using the data of relevant indicators in different sub industries of China’s pharmaceutical industry from 1995 to 2019 based on the theory of covariance.Results and Conclusion The funding of R&D from the government had a significant positive effect on their R&D funding inputs to enterprises with chemo products,Chinese patent products,and biological products.It means the improvement of government funding was beneficial in promoting the R&D investment from various sub industries of pharmaceutical industry.The order of this influence was biological products,chemo products,and Chinese patent drugs.As to chemical drugs and biological products,the government’s R&D funding and enterprises R&D funding input showed a good trend of mutual promotion in a certain lag period.The government can fully leverage its funding to promote the investment of all sub industries of pharmaceutical industry.Meanwhile,regulatory mechanisms should be refined for government funding.For the inheritance,innovation,and development of traditional Chinese medicine,the government should give more policy support than financial support.展开更多
“The silk of Suzhou,Hangzhou,Jiaxing and Huzhou are unrivalled in the world;all under heaven draw their supply from it.”So observed the Ming Dynasty(1368-1644)agronomist Xu Guangqi in his Complete Treatise on Agricu...“The silk of Suzhou,Hangzhou,Jiaxing and Huzhou are unrivalled in the world;all under heaven draw their supply from it.”So observed the Ming Dynasty(1368-1644)agronomist Xu Guangqi in his Complete Treatise on Agriculture,capturing the undisputed dominance of east China in sericulture centuries ago.展开更多
Zuoquan County has revitalized local villages with the fruits of their collected labor.GLOWING red apples hang heavily on branches in the orchards on the southern outskirts of Tongyu Town,Zuoquan County,Shanxi Provinc...Zuoquan County has revitalized local villages with the fruits of their collected labor.GLOWING red apples hang heavily on branches in the orchards on the southern outskirts of Tongyu Town,Zuoquan County,Shanxi Province,an area where a decade ago weeds and rocks covered a rather barren landscape.展开更多
Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may po...Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may pose certain environmental risks.Snow-melting agents and snow samples were collected and analyzed from highways,arterial roads,footbridges,and other locations in Beijing after the snowstorm in December 2023.It was found that the main component of snow-melting agents was sodium chloride with high concentrations of Cu,Mn,and Zn,which are not regulated in the current policies,despite the recent promotion of environmentally friendly snow-melting agents.The Pb,Zn and Cr contents of some snow samples exceeded the limitation value of surface water quality standards,potentially affecting the soil and water environment near roadsides,although the snow-melting agents comply with relevant standards,which indicates the policy gap in the management of recycled industrial salts.We reviewed and analyzed the relevant standards for snow-melting agents and industrial waste salts proposed nationally and internationally over the past 30 years.Through comparative analysis,we proposed relevant policy recommendations to the existing quality standards of snow-melting agents and the management regulations of industrial waste salts,and the formulation of corresponding usage strategies,aimed at reducing the potential environmental release of heavy metals from the use of snow-melting agents,thereby promoting more sustainable green urban development and environmentally sound waste management.展开更多
As an important symbol of agricultural and sideline products in Ankang City,selenium-enriched tea affects the development of regional agricultural and sideline industries.In this paper,the development status and probl...As an important symbol of agricultural and sideline products in Ankang City,selenium-enriched tea affects the development of regional agricultural and sideline industries.In this paper,the development status and problems of the selenium-enriched tea products of Ankang were analyzed in terms of capital,technology,management and sales mode.This research is of positive significance to the development of selenium-enriched products and other agricultural and sideline products of health value,and plays a very important role in promoting the cultivation of village-level characteristic industries and the effective realization of targeted poverty alleviation.展开更多
Based on the analysis of the characteristics and operation status of the process industry,as well as the development of the global intelligent manufacturing industry,a new mode of intelligent manufacturing for the pro...Based on the analysis of the characteristics and operation status of the process industry,as well as the development of the global intelligent manufacturing industry,a new mode of intelligent manufacturing for the process industry,namely,deep integration of industrial artificial intelligence and the Industrial Internet with the process industry,is proposed.This paper analyzes the development status of the existing three-tier structure of the process industry,which consists of the enterprise resource planning,the manufacturing execution system,and the process control system,and examines the decision-making,control,and operation management adopted by process enterprises.Based on this analysis,it then describes the meaning of an intelligent manufacturing framework and presents a vision of an intelligent optimal decision-making system based on human–machine cooperation and an intelligent autonomous control system.Finally,this paper analyzes the scientific challenges and key technologies that are crucial for the successful deployment of intelligent manufacturing in the process industry.展开更多
Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus...Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus on why and what is Industry 5.0 yet.In this paper,we define Industry 5.0from its philosophical and historical origin and evolution,emphasize its new thinking on virtual-real duality and human-machine interaction,and introduce its new theory and technology based on parallel intelligence(PI),artificial societies,computational experiments,and parallel execution(the ACP method),and cyber-physical-social systems(CPSS).Case studies and applications of Industry 5.0 over the last decade have been briefly summarized and analyzed with suggestions for its future development.We believe that Industry 5.0 of virtual-real interactive parallel industries has great potentials and is critical for building smart societies.Steps are outlined to ensure a roadmap that would lead to a smooth transition from CPS-based Industry 4.0 to CPSS-based Industry 5.0 for a better world which is Safe in physical spaces,S ecure in cyberspaces,Sustainable in ecology,Sensitive in individual privacy and rights,Service for all,and Smartness of all.展开更多
The objective of this study was to verify the protective effect of Bifidobacterium longum(BL) and the synergistical effect of Selenium and BL on alcohol plus high fat diet(HFD) induced hepatic injury in mice. We also ...The objective of this study was to verify the protective effect of Bifidobacterium longum(BL) and the synergistical effect of Selenium and BL on alcohol plus high fat diet(HFD) induced hepatic injury in mice. We also want to explore the mechanism of Selenium-enriched Bifidobacterium longum(Se BL). C57 BL/6 mice were treated with alcohol plus HFD with or without different dosage of BL or Se BL for 4 weeks. Serum levels of ALT, AST, TC, TG, LDL-C, HDL-C, FFAs, TNF-α, IL-6 and IL-1β, hepatic MDA level, SOD activity, the m RNA levels of AMPK, PPAR-α and SREBP1 were invested. Se BL inhibited lipid accumulation in hepatocytes;reduced serum AST and ALT levels;improved dyslipidemia;decreased serum FFAs, TC, TG and LDL-C levels. Se BL also inhibited alcohol plus HFD-induced hepatocyte oxidative stress through decrease in hepatic MDA levels and increase in SOD activity. Se BL also regulated lipid metabolism related genes such as AMPK, PPAR-α and SREBP1. Although BL had similar effect as Se BL, Se BL is more effective than BL. Se BL protected mice from alcohol plus HFD-induced hepatic injury in mice because of its inhibitory effect on hepatocellular oxidative stress, lipogenesis and inflammation. Selenium enhanced the protective effect of BL.展开更多
Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and respo...Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and responding to global environmental change. Aiming at a thorough examination of the implementation of ITGP in China, this paper presents its objectives, its three major areas, and their progress so far. It also identifies the key elements of its management and proposes new perspectives on managing green transformation. For instance, we introduce a case study on cement industry that shows the positive policy effects of reducing backward production capacity on PCDD/Fs emissions. Finally,to develop different transformation scenarios for a green future, we propose four strategies: 1) policy integration for promoting green industry, 2)system innovation and a multidisciplinary approach, 3) collaborative governance with all potential stakeholders, and 4) managing uncertainty,risks, and long-time horizons.展开更多
High-salt diet is well recognized as a risk factor for hypertension,and dietary intervention plays a critical role in the prevention of hypertension.The current study investigated the effects of selenium-enriched gree...High-salt diet is well recognized as a risk factor for hypertension,and dietary intervention plays a critical role in the prevention of hypertension.The current study investigated the effects of selenium-enriched green tea(Se-GT)and ordinary green tea(GT)on prevention of hypertension of rats induced by high-salt diet,as well as their potential regulatory and mechanism.Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure(BP),activated the phosphoinosmde-3-kinase/protein kinase B(PI3K/Akt)signaling pathway,and regulated the gene expression related to BP,as well as improved the tissue damage like heart,liver,and kidneys.Besides,the key parameters associated with oxidative stress,inflammation and endothelial dysfunction were also altered by GT and Se-GT treatments.Importantly,GT or Se-GT administration adjusted the diversity and composition of the intestinal flora.Moreover,GT and Se-GT supplementations increased the abundance of beneficial bacteria and reduced the abundance of harmful or conditional pathogenic bacteria.More specifically,GT intake specifically and significantly enriched the relative abundance of Paraprevotella and Bacteroides,whereas Se-GT was characterized by specific and significant enrichment for Allobaculum and Bifidobacterium.Our results proved that dietary supplement of GT and Se-GT remarkably improved the vascular functions and effectively prevented tissue damage by regulation of intestinal flora,and thus preventing hypertension induced by high-salt diet.展开更多
Taking the city of Qitaihe is as an example in order to provide practical methods for the selection of leading industries for coal resource cities, this paper establishes the specific operation scheme for selection of...Taking the city of Qitaihe is as an example in order to provide practical methods for the selection of leading industries for coal resource cities, this paper establishes the specific operation scheme for selection of leading industries according to the actual situation of coal resource cities based on the theory of coupling coordination together with the coupling coordination for technological innovation. The results show that the degree for coupling coordination of the technological innovation for each alternative industry differentiates with the development of coal resource cities. For example, the average degree of food processing industry from agricultural produce is 0.9. Therefore, coal resource cities should develop some industries related to coal industry, such as coking industry, some chemical and medicines industry and non-metallic mineral products manufacturing, in the near future, however, some industries with greater market and influence potentials and low carbon emissions should be attached much importance to in the future.展开更多
In the process of industrialization of tomato industry in Xinjiang, the cooperative models of rural households and tomato processing enterprises are order type, mediated type and workshop type. The contents, closeness...In the process of industrialization of tomato industry in Xinjiang, the cooperative models of rural households and tomato processing enterprises are order type, mediated type and workshop type. The contents, closeness degree and stability of cooperation of them are different. Under different cooperation models, the closeness degree of pillar industry and rural households differs, as well as the speed and effect of the technology promotion. By comparing the situation of technology promotion under the three cooperative models, the results can be obtained. The workshop type can reduce the risks of adopting new technologies of farmers greatly; strengthen the internal motivation of farmers to adopt new technology, so it can attract more farmers. Therefore, the workshop type represents the developmental direction of industrialization of tomato industry in Xinjiang to a certain extent.展开更多
[Objectives] The aims were to optimize the extraction process of selenoproteins from selenium-enriched rice in Guangxi and provide references for the intensive processing and comprehensive utilization of selenium prot...[Objectives] The aims were to optimize the extraction process of selenoproteins from selenium-enriched rice in Guangxi and provide references for the intensive processing and comprehensive utilization of selenium protein resources. [Methods]Selenium-enriched rice was used as materials to extract selenoproteins by phosphate buffer extraction method and to optimize the extraction process of selenoproteins by using the orthogonal experiment. Proteins and selenium content was measured by Coomassie Brilliant Blue G-250 reagent and AFS（ atomic fluorescence spectrometry） respectively. [Results] The most significant factor affecting extraction of rice Selenoproteins was extraction NaO H concentration,followed by the ratio of solid-liquid,temperature and then extraction time. The optimum extraction conditions of selenoproteins from rice were extraction temperature of 50 ℃,NaO H concentration of 0. 14 mol/L,extraction time of 5 h,and solid-liquid ratio of 1∶ 30. [Conclusions]The alkali extraction process optimized by orthogonal test could effectively improve the extraction rate of selenoproteins,and the optimized process parameters could be popularized and applied in practical production.展开更多
As the significant regional development driving,industry agglomeration has become one of the most interested for industrial economist and regional economist.This paper chooses the main five E&I industrial parks in...As the significant regional development driving,industry agglomeration has become one of the most interested for industrial economist and regional economist.This paper chooses the main five E&I industrial parks in Shaanxi Province as the research object,and systematically compares their industry agglomerations,such as the situations,patterns,development approaches,and so on.Finally,based on the situation of the five E&I industrial parks,combined with the power and the attraction of sub-sectors industry,some suggestions on the formation and consolidation of agglomeration effect for each park are proposed.展开更多
基金Supported by Beijing Municipal Natural Science Foundation of China(Grant No.24JL002)China Postdoctoral Science Foundation(Grant No.2024M754054)+2 种基金National Natural Science Foundation of China(Grant No.52120105008)Beijing Municipal Outstanding Young Scientis Program of Chinathe New Cornerstone Science Foundation through the XPLORER PRIZE。
文摘With the continuous advancement and maturation of technologies such as big data,artificial intelligence,virtual reality,robotics,human-machine collaboration,and augmented reality,many enterprises are finding new avenues for digital transformation and intelligent upgrading.Industry 5.0,a further extension and development of Industry 4.0,has become an important development trend in industry with more emphasis on human-centered sustainability and flexibility.Accordingly,both the industrial metaverse and digital twins have attracted much attention in this new era.However,the relationship between them is not clear enough.In this paper,a comparison between digital twins and the metaverse in industry is made firstly.Then,we propose the concept and framework of Digital Twin Systems Engineering(DTSE)to demonstrate how digital twins support the industrial metaverse in the era of Industry 5.0 by integrating systems engineering principles.Furthermore,we discuss the key technologies and challenges of DTSE,in particular how artificial intelligence enhances the application of DTSE.Finally,a specific application scenario in the aviation field is presented to illustrate the application prospects of DTSE.
基金supported by the National Natural Science Foundation of China(32302774)Beijing Innovation Consortium of Agriculture Research System(BAIC04)+1 种基金China Agriculture Research System(CARS-40)the Agricultural Science and Technology Innovation Program of the Feed Research Institute of the Chinese Academy of Agricultural Sciences(CAASIFR-ZDRW202402).
文摘Background Organic selenium(Se)has gained recognition in poultry nutrition as a feed additive to boost production and Se deposition in eggs and tissues,owing to its high bioavailability,efficient tissue accumulation and minimal toxicity.Selenium-enriched yeast(SeY)is a well-established source,while selenium-enriched lactobacilli(SeL),a newer alternative,offers the added benefits of probiotics.This study examined the effects of SeY and SeL on egg quality,antioxidant capacity,Se deposition,and gut health in laying hens.After a two-week pre-treatment with a Sedeficient diet(SeD),450 Hy-Line Brown laying hens(30-week-old)were assigned into five dietary groups with six replicates of 15 hens each.The groups included a SeD,SeD supplemented with 1.5 mg Se/kg from SeY(SeY15),or 1.5,3.0,and 6.0 mg Se/kg from SeL(SeL15,SeL30,SeL60).The feeding trial lasted for 12 weeks.Results SeY15 and SeL15 improved the feed-to-egg ratio(P<0.05)in the latter stages.Haugh units were significantly increased(P<0.05)in the SeY15 and SeL30 groups,while darker yolk color(P<0.05)was observed in the SeY15,SeL15,and SeL60 groups.All Se-supplemented diets increased Se content in whole eggs,albumen,and yolk(P<0.05),while SeL groups showed a dose-dependent effect.Antioxidant enzyme activities increased,and MDA content decreased in the serum(P<0.05),with SeY15 showing the highest GSH-Px levels(P<0.05).SeL60 increased serum alkaline phosphatase and aspartate transaminase,and distorted the liver architecture(P<0.05).Se-diets reduced concentrations of reactive oxygen species(ROS)in the ileum and liver(P<0.05).SeL15 improved the ileal villus height-tocrypt depth ratio(P<0.05).SeY15 and/or SeL15 up-regulated TXNRD1 and SEPHS1 mRNA while down-regulating SCLY expression in the liver.SeY15 altered ileal microbiota by increasing both beneficial and pathogenic bacteria,whereas SeL15 predominantly boosted beneficial bacteria.Conclusion SeL integrates the antioxidant properties of organic Se with the probiotic benefits on gut health,resulting in a performance-enhancing effect comparable to that of SeY.However,high SeL level(6.0 mg Se/kg)compromised productivity and metabolic functions while enhancing Se deposition.
基金Supported by General Project of Philosophy and Social Sciences Research in Universities of Jiangsu Province,2024(2024SJYB1650).
文摘Based on the requirements of local high-quality economic development and addressing the critical task of transformation and upgrading in the tea industry,this paper systematically discusses the necessity and feasibility of constructing an optimal industrialization operation system driven by the dual wheels of"branding+standardization".The article first clarifies the connotation of high-quality development and the synergistic mechanism between branding and standardization.It then analyzes the current situation and bottlenecks of China's tea industry development.Subsequently,it proposes a dual-wheel drive strategy where branding enhances value and standardization guarantees quality,and designs a systematic implementation plan involving industrial chain synergy optimization and integrated support from government,industry,academia,research,and application.On this basis,strategies and suggestions are proposed,encompassing the starting point,standard focal points,key effort areas,innovation points,and target achievement points.The aim is to promote the tea industry to break through homogeneous competition,achieve value ascent,and provide important industrial support for regional high-quality development through the construction of the aforementioned system.
文摘The rapid evolution of industrial robots from automation tools to intelligent systems marks a pivotal shift in manufacturing practices within the framework of Industry 4.0.Industrial robots,once limited to repetitive tasks on assembly lines,are now increasingly powered by advanced technologies such as Artificial Intelligence(AI),machine learning,and the Internet of Things(IoT),enabling them to perform complex,adaptive tasks in real-time.This paper explores the technological advancements that have transformed industrial robots,highlighting the integration of AI,smart sensors,and autonomous systems.Furthermore,it examines the implications of this paradigm shift for industries,human-robot collaboration,and the workforce.While intelligent robots promise greater efficiency,flexibility,and safety in manufacturing,challenges regarding implementation,economic impact,and ethical considerations remain significant.The paper concludes by looking at the future trends in robotics and their potential to reshape the global industrial landscape.
文摘The“government-industry-university-research”model has significant practical significance in promoting the development of industries in colleges and universities and improving the quality of talent cultivation.This paper first provides a brief explanation of the concept and significance of the“government-industry-university-research”model,then conducts an in-depth analysis of the problems faced by the development of university industries,and finally proposes effective solutions to the problems faced by the development of university industries,hoping to provide some references and lessons for promoting the continuous development of university industries and the integration of industry and education.
基金funded by the National Key Research and Development Program of China(2024YFC3506900)the Special Project for Technological Innovation in New Productive Forces of Modern Chinese Medicines(24ZXZKSY00010 and 24ZXZKSY00040)the Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine(ZYYCXTD-D-202002)。
文摘Extraction unit operation is the first step in traditional Chinese medicine(TCM)product manufacturing,and it is crucial in determining the quality of the produced medicine.However,due to a lack of effective multimodal monitoring and adjustment strategies,achieving high quality and efficiency remains a challenge.In this work,we proposed an artificial intelligence(AI)-based robot platform for the multi-objective optimization of the extraction process.First,a perception intelligence method for multimodal process monitoring was established to track active ingredient transfer and production changes during the extraction process.Second,a digital twin model was developed to reconstruct the field information,which interacted with real-time monitoring data.Furthermore,the model performed real-time inference to predict future production process states by using the reconstructing information.Finally,according to the predicted process states,the autonomous decision-making robot implemented multi-objective optimization,ensuring efficient process adjustments for global optimization.Experimental and industrial results demonstrated that the platform could effectively infer component transfer dynamics,monitor temperature variations,and identify boiling states,ensuring product quality while reducing energy consumption.This pharmaceutical robot could promote the integration of AI and pharmaceutical engineering,thereby accelerating the iterative development and improvement of China’s pharmaceutical industry.
文摘Objective To empirically analyze the relationship between Government R&D funding and R&D investment of the enterprises in different sub industries of pharmaceutical industry,and to provide reference for the development of policies related to R&D funding input.Methods Granger causality test was performed using the data of relevant indicators in different sub industries of China’s pharmaceutical industry from 1995 to 2019 based on the theory of covariance.Results and Conclusion The funding of R&D from the government had a significant positive effect on their R&D funding inputs to enterprises with chemo products,Chinese patent products,and biological products.It means the improvement of government funding was beneficial in promoting the R&D investment from various sub industries of pharmaceutical industry.The order of this influence was biological products,chemo products,and Chinese patent drugs.As to chemical drugs and biological products,the government’s R&D funding and enterprises R&D funding input showed a good trend of mutual promotion in a certain lag period.The government can fully leverage its funding to promote the investment of all sub industries of pharmaceutical industry.Meanwhile,regulatory mechanisms should be refined for government funding.For the inheritance,innovation,and development of traditional Chinese medicine,the government should give more policy support than financial support.
文摘“The silk of Suzhou,Hangzhou,Jiaxing and Huzhou are unrivalled in the world;all under heaven draw their supply from it.”So observed the Ming Dynasty(1368-1644)agronomist Xu Guangqi in his Complete Treatise on Agriculture,capturing the undisputed dominance of east China in sericulture centuries ago.
文摘Zuoquan County has revitalized local villages with the fruits of their collected labor.GLOWING red apples hang heavily on branches in the orchards on the southern outskirts of Tongyu Town,Zuoquan County,Shanxi Province,an area where a decade ago weeds and rocks covered a rather barren landscape.
基金supported by the National Natural Science Foundation of China(No.22176200)the Industrial Innovation Entrepreneurial Team Project of Ordos 2021.
文摘Industrial waste salts are commonly used to make value-added snow-melting agents to ensure traffic safety in northern China during winter and spring after snowfall.However,heavy metals in industrial waste salts may pose certain environmental risks.Snow-melting agents and snow samples were collected and analyzed from highways,arterial roads,footbridges,and other locations in Beijing after the snowstorm in December 2023.It was found that the main component of snow-melting agents was sodium chloride with high concentrations of Cu,Mn,and Zn,which are not regulated in the current policies,despite the recent promotion of environmentally friendly snow-melting agents.The Pb,Zn and Cr contents of some snow samples exceeded the limitation value of surface water quality standards,potentially affecting the soil and water environment near roadsides,although the snow-melting agents comply with relevant standards,which indicates the policy gap in the management of recycled industrial salts.We reviewed and analyzed the relevant standards for snow-melting agents and industrial waste salts proposed nationally and internationally over the past 30 years.Through comparative analysis,we proposed relevant policy recommendations to the existing quality standards of snow-melting agents and the management regulations of industrial waste salts,and the formulation of corresponding usage strategies,aimed at reducing the potential environmental release of heavy metals from the use of snow-melting agents,thereby promoting more sustainable green urban development and environmentally sound waste management.
基金National Key R&D Program of China(2018YFD1100202)Shaanxi Social Science Fund Program of China(2018S30)Shaanxi Undergraduate Innovation Planning Project of China(201829041).
文摘As an important symbol of agricultural and sideline products in Ankang City,selenium-enriched tea affects the development of regional agricultural and sideline industries.In this paper,the development status and problems of the selenium-enriched tea products of Ankang were analyzed in terms of capital,technology,management and sales mode.This research is of positive significance to the development of selenium-enriched products and other agricultural and sideline products of health value,and plays a very important role in promoting the cultivation of village-level characteristic industries and the effective realization of targeted poverty alleviation.
基金This research was supported by the National Natural Science Foundation of China(61991400,61991403,and 61991404)China Institute of Engineering Consulting Research Project(2019-ZD-12)the 2020 Science and Technology Major Project of Liaoning Province(2020JH1/10100008),China.
文摘Based on the analysis of the characteristics and operation status of the process industry,as well as the development of the global intelligent manufacturing industry,a new mode of intelligent manufacturing for the process industry,namely,deep integration of industrial artificial intelligence and the Industrial Internet with the process industry,is proposed.This paper analyzes the development status of the existing three-tier structure of the process industry,which consists of the enterprise resource planning,the manufacturing execution system,and the process control system,and examines the decision-making,control,and operation management adopted by process enterprises.Based on this analysis,it then describes the meaning of an intelligent manufacturing framework and presents a vision of an intelligent optimal decision-making system based on human–machine cooperation and an intelligent autonomous control system.Finally,this paper analyzes the scientific challenges and key technologies that are crucial for the successful deployment of intelligent manufacturing in the process industry.
基金partially supported by the Science and Technology Development Fund of Macao SAR(0050/2020/A1)。
文摘Very recently,intensive discussions and studies on Industry 5.0 have sprung up and caused the attention of researchers,entrepreneurs,and policymakers from various sectors around the world.However,there is no consensus on why and what is Industry 5.0 yet.In this paper,we define Industry 5.0from its philosophical and historical origin and evolution,emphasize its new thinking on virtual-real duality and human-machine interaction,and introduce its new theory and technology based on parallel intelligence(PI),artificial societies,computational experiments,and parallel execution(the ACP method),and cyber-physical-social systems(CPSS).Case studies and applications of Industry 5.0 over the last decade have been briefly summarized and analyzed with suggestions for its future development.We believe that Industry 5.0 of virtual-real interactive parallel industries has great potentials and is critical for building smart societies.Steps are outlined to ensure a roadmap that would lead to a smooth transition from CPS-based Industry 4.0 to CPSS-based Industry 5.0 for a better world which is Safe in physical spaces,S ecure in cyberspaces,Sustainable in ecology,Sensitive in individual privacy and rights,Service for all,and Smartness of all.
基金National Natural Science Foundation of China(Nos.81872917 and 81741164)。
文摘The objective of this study was to verify the protective effect of Bifidobacterium longum(BL) and the synergistical effect of Selenium and BL on alcohol plus high fat diet(HFD) induced hepatic injury in mice. We also want to explore the mechanism of Selenium-enriched Bifidobacterium longum(Se BL). C57 BL/6 mice were treated with alcohol plus HFD with or without different dosage of BL or Se BL for 4 weeks. Serum levels of ALT, AST, TC, TG, LDL-C, HDL-C, FFAs, TNF-α, IL-6 and IL-1β, hepatic MDA level, SOD activity, the m RNA levels of AMPK, PPAR-α and SREBP1 were invested. Se BL inhibited lipid accumulation in hepatocytes;reduced serum AST and ALT levels;improved dyslipidemia;decreased serum FFAs, TC, TG and LDL-C levels. Se BL also inhibited alcohol plus HFD-induced hepatocyte oxidative stress through decrease in hepatic MDA levels and increase in SOD activity. Se BL also regulated lipid metabolism related genes such as AMPK, PPAR-α and SREBP1. Although BL had similar effect as Se BL, Se BL is more effective than BL. Se BL protected mice from alcohol plus HFD-induced hepatic injury in mice because of its inhibitory effect on hepatocellular oxidative stress, lipogenesis and inflammation. Selenium enhanced the protective effect of BL.
基金funded by the Chinese Academy of Sciences (KZZD-EW-TZ-12)National Natural Science Foundation of China (414201040045 and 41371488)Natural Science Foundation of Hainan Province (413129)
文摘Industrial transformation and green production(ITGP) is a new 10-year international research initiative proposed by the Chinese National Committee for Future Earth. It is also an important theme for adapting and responding to global environmental change. Aiming at a thorough examination of the implementation of ITGP in China, this paper presents its objectives, its three major areas, and their progress so far. It also identifies the key elements of its management and proposes new perspectives on managing green transformation. For instance, we introduce a case study on cement industry that shows the positive policy effects of reducing backward production capacity on PCDD/Fs emissions. Finally,to develop different transformation scenarios for a green future, we propose four strategies: 1) policy integration for promoting green industry, 2)system innovation and a multidisciplinary approach, 3) collaborative governance with all potential stakeholders, and 4) managing uncertainty,risks, and long-time horizons.
基金financial sponsored by the National Key R&D Program of China(No.2018YFC1604405)Fund of Shanghai Engineering Research Center of Plant Germplasm Resources(No.17DZ2252700)Research on the health function of tea and deep-processed products in preventing metabolic diseases(No.C-6105-20-074)。
文摘High-salt diet is well recognized as a risk factor for hypertension,and dietary intervention plays a critical role in the prevention of hypertension.The current study investigated the effects of selenium-enriched green tea(Se-GT)and ordinary green tea(GT)on prevention of hypertension of rats induced by high-salt diet,as well as their potential regulatory and mechanism.Our results showed that GT and Se-GT supplementations significantly prevented the increase of blood pressure(BP),activated the phosphoinosmde-3-kinase/protein kinase B(PI3K/Akt)signaling pathway,and regulated the gene expression related to BP,as well as improved the tissue damage like heart,liver,and kidneys.Besides,the key parameters associated with oxidative stress,inflammation and endothelial dysfunction were also altered by GT and Se-GT treatments.Importantly,GT or Se-GT administration adjusted the diversity and composition of the intestinal flora.Moreover,GT and Se-GT supplementations increased the abundance of beneficial bacteria and reduced the abundance of harmful or conditional pathogenic bacteria.More specifically,GT intake specifically and significantly enriched the relative abundance of Paraprevotella and Bacteroides,whereas Se-GT was characterized by specific and significant enrichment for Allobaculum and Bifidobacterium.Our results proved that dietary supplement of GT and Se-GT remarkably improved the vascular functions and effectively prevented tissue damage by regulation of intestinal flora,and thus preventing hypertension induced by high-salt diet.
基金provided by the National Natural Science Foundation of China (No. 70972098)
文摘Taking the city of Qitaihe is as an example in order to provide practical methods for the selection of leading industries for coal resource cities, this paper establishes the specific operation scheme for selection of leading industries according to the actual situation of coal resource cities based on the theory of coupling coordination together with the coupling coordination for technological innovation. The results show that the degree for coupling coordination of the technological innovation for each alternative industry differentiates with the development of coal resource cities. For example, the average degree of food processing industry from agricultural produce is 0.9. Therefore, coal resource cities should develop some industries related to coal industry, such as coking industry, some chemical and medicines industry and non-metallic mineral products manufacturing, in the near future, however, some industries with greater market and influence potentials and low carbon emissions should be attached much importance to in the future.
基金Supported by Major Biding Projects by National Social Science Fund(07&ZD026)
文摘In the process of industrialization of tomato industry in Xinjiang, the cooperative models of rural households and tomato processing enterprises are order type, mediated type and workshop type. The contents, closeness degree and stability of cooperation of them are different. Under different cooperation models, the closeness degree of pillar industry and rural households differs, as well as the speed and effect of the technology promotion. By comparing the situation of technology promotion under the three cooperative models, the results can be obtained. The workshop type can reduce the risks of adopting new technologies of farmers greatly; strengthen the internal motivation of farmers to adopt new technology, so it can attract more farmers. Therefore, the workshop type represents the developmental direction of industrialization of tomato industry in Xinjiang to a certain extent.
基金Supported by the Science and Technology Major Project of Guangxi(Guike AA17202026)Program for Scientific Research and Technology Development in Xixiangtant District of Nanning City(201710304)+7 种基金the Special Fund for the Innovation-Driven Development in Guangxi(Guike AA17202019-4&AA17202019)the Science and Technology Development Fund of Guangxi Academy of Agricultural Sciences(Guinongke 2017JM03)the Program for the Scientific Research and Technology Development in Guangxi(Guikehe415104001-22)the Fundamental Research Funds for Guangxi Academy of Agricultural Sciences(Guinongke 2017YZ03)the Key Research and Development Program of Guangxi(Guike AB16380088)the Experiment Station for Selenium Featured Crops in Guangxi(Gui TS2016011)the Key Research and Development Program of Qingxiu District,Guangxi(2016039)the Scientific and Technological Transformative Project of Guangxi Academy of Agricultural Sciences(NO.2017NZ04)
文摘[Objectives] The aims were to optimize the extraction process of selenoproteins from selenium-enriched rice in Guangxi and provide references for the intensive processing and comprehensive utilization of selenium protein resources. [Methods]Selenium-enriched rice was used as materials to extract selenoproteins by phosphate buffer extraction method and to optimize the extraction process of selenoproteins by using the orthogonal experiment. Proteins and selenium content was measured by Coomassie Brilliant Blue G-250 reagent and AFS（ atomic fluorescence spectrometry） respectively. [Results] The most significant factor affecting extraction of rice Selenoproteins was extraction NaO H concentration,followed by the ratio of solid-liquid,temperature and then extraction time. The optimum extraction conditions of selenoproteins from rice were extraction temperature of 50 ℃,NaO H concentration of 0. 14 mol/L,extraction time of 5 h,and solid-liquid ratio of 1∶ 30. [Conclusions]The alkali extraction process optimized by orthogonal test could effectively improve the extraction rate of selenoproteins,and the optimized process parameters could be popularized and applied in practical production.
文摘As the significant regional development driving,industry agglomeration has become one of the most interested for industrial economist and regional economist.This paper chooses the main five E&I industrial parks in Shaanxi Province as the research object,and systematically compares their industry agglomerations,such as the situations,patterns,development approaches,and so on.Finally,based on the situation of the five E&I industrial parks,combined with the power and the attraction of sub-sectors industry,some suggestions on the formation and consolidation of agglomeration effect for each park are proposed.
