Hirschsprung’s disease(HSCR)results from neural crest cell migration and differentiation issues.1 Previously,analysis was limited to bulk tissue samples,but single-cell RNA sequencing now offers microscopic insights....Hirschsprung’s disease(HSCR)results from neural crest cell migration and differentiation issues.1 Previously,analysis was limited to bulk tissue samples,but single-cell RNA sequencing now offers microscopic insights.Our pioneering single-cell RNA sequencing analysis of colon tissue is helping unravel HSCR’s origins and development.展开更多
基金supported by the National Natural Science Foundation of China(No.81770514,81270439).
文摘Hirschsprung’s disease(HSCR)results from neural crest cell migration and differentiation issues.1 Previously,analysis was limited to bulk tissue samples,but single-cell RNA sequencing now offers microscopic insights.Our pioneering single-cell RNA sequencing analysis of colon tissue is helping unravel HSCR’s origins and development.
