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International Symposium Themed“Strengthen the Role of the United Nations and Promote Multilateralism”Held in Beijing
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《China International Studies》 2025年第2期F0002-F0002,共1页
On March 24,the international symposium themed“Strengthen the Role of the United Nations and Promote Multilateralism”was held in Beijing.The event was hosted by the Ministry of Foreign Affairs of China,and supported... On March 24,the international symposium themed“Strengthen the Role of the United Nations and Promote Multilateralism”was held in Beijing.The event was hosted by the Ministry of Foreign Affairs of China,and supported by China Institute of International Studies(CIIS),the United Nations Association of China. 展开更多
关键词 united nations association MULTILATERALISM PROMOTE role promote multilateralism united nations STRENGTHEN role united nations
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The Role Adaptation of Rural Primary School Teachers:Challenges and Solutions
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作者 Zhaoyang Zhang 《Journal of Contemporary Educational Research》 2025年第3期9-16,共8页
This study examines the role adaptation of rural primary school teachers through a literature review,summarizing the current research on general practice teachers and identifying emerging trends.Interviews were conduc... This study examines the role adaptation of rural primary school teachers through a literature review,summarizing the current research on general practice teachers and identifying emerging trends.Interviews were conducted with four rural primary school teachers,revealing key challenges:an incomplete understanding of their responsibilities as head teachers,a lack of theoretical and practical guidance in their role as learners,and insufficient research skills in their role as researchers.To address these issues,the study recommends reducing the number of subjects taught by general practice teachers in rural primary schools and providing targeted training,strengthening professional guidance and improving compensation,offering high-quality learning resources and encouraging further education,and establishing educational alliances to enhance teachers’research capabilities. 展开更多
关键词 General practice teacher Teacher role role adaptation
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Recent advances of metal vacancies in energy and environmental catalysis:Synthesis,characterization,and roles
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作者 Long Sun Shunzheng Zhao +4 位作者 Sirui Gao Ronghui Zhu Yiran Tan Xiaolong Tang Honghong Yi 《Green Energy & Environment》 SCIE EI CAS 2025年第1期84-108,共25页
With the ongoing depletion of fossil fuels,energy and environmental issues have become increasingly critical,necessitating the search for effective solutions.Catalysis,being one of the hallmarks of modern industry,off... With the ongoing depletion of fossil fuels,energy and environmental issues have become increasingly critical,necessitating the search for effective solutions.Catalysis,being one of the hallmarks of modern industry,offers a promising avenue for researchers.However,the question of how to significantly enhance the performance of catalysts has gradually drawn the attention of scholars.Defect engineering,a commonly employed and effective approach to improve catalyst activity,has become a significant research focus in the catalysis field in recent years.Nonmetal vacancies have received extensive attention due to their simple form.Consequently,exploration of metal vacancies has remained stagnant for a considerable period,resulting in a scarcity of comprehensive reviews on this topic.Therefore,based on the latest research findings,this paper summarizes and consolidates the construction strategies for metal vacancies,characterization techniques,and their roles in typical energy and environmental catalytic reactions.Additionally,it outlines potential challenges in the future,aiming to provide valuable references for researchers interested in investigating metal vacancies. 展开更多
关键词 Metal vacancies CATALYSIS Construction strategies Characterization techniques roleS
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The Accountant’s Role in the Era of Artificial Intelligence(AI)and Automation:Transforming Skills and Responsibilities
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作者 Adryanni Manurung Nengsyh Untari Panjaitan +1 位作者 Iskandar Muda Erlina 《Journal of Modern Accounting and Auditing》 2025年第3期197-208,共12页
The rapid advancement of Artificial Intelligence(AI)and automation has significantly transformed the accounting profession,shifting the role of accountants from routine data processors to strategic decision makers and... The rapid advancement of Artificial Intelligence(AI)and automation has significantly transformed the accounting profession,shifting the role of accountants from routine data processors to strategic decision makers and ethical stewards of technology.This conceptual study explores how AI and automation are reshaping accounting tasks,transforming required competencies,and redefining professional responsibilities.By analyzing relevant literature and theoretical frameworks,this paper identifies the evolving skill sets,both technical such as data analytics and AI literacy,and nontechnical such as critical thinking and ethical judgment,that are essential for modern accountants.The study also emphasizes the importance of continuous education,ethical integrity,and adaptive learning in navigating the digital transformation of accounting.Ultimately,this paper contributes to a deeper understanding of how accountants can maintain relevance and add value in an increasingly automated and data driven environment. 展开更多
关键词 artificial intelligence AUTOMATION ACCOUNTANT role transformation accounting skills
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The Path to Enhance Career Adaptability of Novice University Teachers:The Mediating Role of Organizational Support and Self-Efficacy
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作者 Zhenlong Yan Hsin Chang 《Journal of Contemporary Educational Research》 2025年第7期306-311,共6页
This study examines how organizational support influences the career adaptability of novice university teachers in Guangdong,China,and the mediating role of teacher self-efficacy.Drawing on social cognitive theory and... This study examines how organizational support influences the career adaptability of novice university teachers in Guangdong,China,and the mediating role of teacher self-efficacy.Drawing on social cognitive theory and organizational support theory,we hypothesized that organizational support would positively predict career adaptability through self-efficacy.A cross-sectional survey was conducted with 326 novice teachers(with 1–3 years of teaching experience)from 12 universities in Guangdong.Data were analyzed using correlation analysis,hierarchical regression,and bootstrap.Results showed that:(1)organizational support was positively associated with both self-efficacy(r=0.62,P<0.001)and career adaptability(r=0.58,P<0.001);(2)self-efficacy fully mediated the relationship between organizational support and career adaptability(indirect effect=0.24,95%CI[0.18,0.31]),with a partial reduction in the direct effect fromβ=0.35 toβ=0.17(P<0.05);(3)female teachers reported higher self-efficacy than males(P<0.05),and teachers with 2 years of experience showed significantly higher adaptability than those with 1 year(P<0.05).The findings highlight the critical role of self-efficacy in translating organizational support into adaptability,providing empirical evidence for universities to design targeted support strategies. 展开更多
关键词 Organizational support Novice teachers Career adaptability SELF-EFFICACY Mediating role
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Xi Jinping Focus: Xi Jinping stresses role of education in supporting sci-tech, talent development
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《China Rare Earth Information》 2025年第1期1-1,共1页
Chinese President Xi Jinping on March 6,2025,stressed strengthening the role of education in supporting scientific and technological advancement as well as talent development.
关键词 scientific technological advancement EDUCATION strengthening role education talent development
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Work-family behavioral role conflict and daytime sleepiness on suicide risk among Chinese nurses:A cross-sectional study
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作者 Qing-Wen Gan Yi-Ling Yuan +2 位作者 Yuan-Ping Li Yi-Wen Du Li-Lan Zheng 《World Journal of Psychiatry》 2025年第2期152-160,共9页
BACKGROUND Work-family conflicts and daytime sleepiness are related to the risk of suicide.At present,no study has investigated the relationship between nurses’work-family behavioral role conflict and suicide risk.Mo... BACKGROUND Work-family conflicts and daytime sleepiness are related to the risk of suicide.At present,no study has investigated the relationship between nurses’work-family behavioral role conflict and suicide risk.Moreover,it has not been confirmed whether,considering the effect of daytime sleepiness on suicide risk,daytime sleepiness mediates the effect of work-family behavioral role conflict and suicide risk.AIM To explore the pathway relationships among nurses'work-family behavioral role conflict,daytime sleepiness,and suicide risk.METHODS Convenience and purposive sampling methods were used to select 750 nurses from six provinces,including Jiangxi,Sichuan,and Shanxi.The work-family behavioral role conflict scale,the Chinese adult daytime sleepiness scale,and the suicide behavior questionnaire were used for the survey.The data were statistically analyzed via SPSS 25.0 software,Pearson correlation analysis was used to explore the correlations between the variables,the PROCESS 4.0 program was used for the mediation effect analysis,and the mediation effect model was tested via the bootstrap method.RESULTS Nurses'work-family behavioral role conflict and daytime sleepiness were positively correlated with suicide risk(r=734,0.717).Work-family behavioral role conflict positively predicted suicide risk(β=0.118),and daytime sleepiness positively predicted suicide risk(β=0.152).Daytime sleepiness partially mediated the role of nurses'work-family behavioral role conflict and suicide risk,with a mediation effect value of 0.046 and a mediation effect accounting for 38.98%.CONCLUSION The results of the Pearson correlation analysis and mediation effect analysis revealed that nurses'work-family behavioral role conflict has a direct effect on suicide risk and indirectly affects suicide risk through daytime drowsiness symptoms. 展开更多
关键词 Work-family behavioral role conflict Daytime sleepiness Suicide risk Mediating effect Nurses
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Contemporary Role of Traditional Ecological Wisdom of Ethnic Groups in China--In the Case of Yi People
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作者 ZHANG Weiwen 《Cultural and Religious Studies》 2025年第3期121-130,共10页
Based on deep realization in relationship between human beings and environment,Yi people gradually formed high level ecological wisdom,which not only protects the environment very well where they are living in,but als... Based on deep realization in relationship between human beings and environment,Yi people gradually formed high level ecological wisdom,which not only protects the environment very well where they are living in,but also maintains their survival and development.Importantly,such traditional ecological wisdom will be very helpful for environmental protection and sustainable development of human beings,especially in the background of modern industrial civilization. 展开更多
关键词 ethnic groups ecological wisdom role
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Mixed lineage kinase domain-like protein in liver diseases:Cell-typespecific functions and dual roles
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作者 Ming-Xing Liang Ying Zhou +4 位作者 Su-Qun Li Wan-Sheng Xiang Zong-Qin Pan Ying-Hua Chen Yi-Huai He 《World Journal of Gastroenterology》 2025年第14期161-167,共7页
In this letter,we comment on the article by Xuan Yuan et al,published in the recent issue of the World Journal of Gastroenterology.Mixed lineage kinase domainlike protein(MLKL)exhibits cell-type-specific functions in ... In this letter,we comment on the article by Xuan Yuan et al,published in the recent issue of the World Journal of Gastroenterology.Mixed lineage kinase domainlike protein(MLKL)exhibits cell-type-specific functions in liver parenchymal and non-parenchymal cells,playing dual roles in the pathogenesis of liver diseases.In hepatocytes,MLKL primarily mediates necroptosis and inhibits autophagy,thereby exacerbating liver injury.Conversely,in non-parenchymal liver cells,MLKL modulates inflammatory responses and promotes fibrotic processes,thereby driving disease progression.Notably,MLKL also demonstrates protective functions under specific conditions.For instance,MLKL can inhibit intracellular bacterial replication,promote endosomal trafficking,and facilitate the generation and release of extracellular vesicles,potentially exerting hepatoprotective effects.Understanding these cell-type-specific mechanisms of MLKL action,including its dual roles in promoting injury and providing protection,is crucial for elucidating the complex pathogenesis of liver diseases and developing targeted therapeutic strategies. 展开更多
关键词 Cell-type-specific functions Dual roles Liver diseases Mixed lineage kinase domain-like protein NECROPTOSIS
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The Predictive Roles of Foreign Language Anxiety, Enjoyment, and Boredom on Chinese Students’ English Achievements
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作者 LIN Huachun WANG Chen 《Sino-US English Teaching》 2025年第5期163-173,共11页
This study examines the predictive roles of foreign language classroom anxiety(FLCA),foreign language enjoyment(FLE),and foreign language boredom(FLB)in English achievement among Chinese senior high school students.De... This study examines the predictive roles of foreign language classroom anxiety(FLCA),foreign language enjoyment(FLE),and foreign language boredom(FLB)in English achievement among Chinese senior high school students.Despite extensive research on anxiety in language learning,less attention has been given to boredom,and the combined effects of these three emotions on English achievement remain under-explored,particularly among high school students in China.To address these gaps,a sample of 142 students from Guangzhou was surveyed using questionnaires to assess their emotional experiences and English achievement.The research found that FLE exhibited a positive correlation with academic performance,while FLCA and FLB showed negative associations.Notably,FLE was the most significant predictor of English achievement,followed by FLCA and FLB.Gender differences were observed,with male students reporting significantly higher levels of environmental enjoyment,while female students experienced significantly greater communication anxiety.On this basis,this paper offers suggestions on how to enhance senior high school students’FLE while mitigating FLCA and FLB,thereby promoting more effective and sustained English learning. 展开更多
关键词 foreign language anxiety foreign language enjoyment foreign language boredom English achievement predictive roles
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Outcomes of patients receiving extracorporeal membrane oxygenation:Direct vs consultative advanced heart failure and transplant cardiology physicians’role
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作者 Gemechu Dereje Feyissa 《World Journal of Transplantation》 2025年第4期497-502,共6页
This manuscript provides a commentary on the article by Zhang et al.Patients with heart and pulmonary failure who do not respond to standard treatment may benefit from extracorporeal membrane oxygenation(ECMO)support.... This manuscript provides a commentary on the article by Zhang et al.Patients with heart and pulmonary failure who do not respond to standard treatment may benefit from extracorporeal membrane oxygenation(ECMO)support.Advanced heart failure and transplant cardiology(AHFTC)teams play an essential role in managing patients in cardiogenic shock.To determine whether ECMO patient management outcomes differ based on whether AHFTC physicians assume a direct or consultative role,a retrospective cohort study of 51 patients placed on veno-venous and veno-arterial(VA)ECMO between January 2015 and February 2023 was conducted.Results demonstrated a significantly higher 30-day postdischarge survival rate in the AHFTC direct involvement cohort compared to the consultative group(67%vs 30%)for all ECMO patients.This survival benefit was primarily attributable to VA ECMO patients(64%vs 20%).Direct involvement of AHFTC teams in patient selection and management may enhance survival in patients requiring VA ECMO for cardiogenic shock;however,further research is necessary to confirm these findings. 展开更多
关键词 Advanced heart failure Critical care Extracorporeal membrane oxygenation MORTALITY Patients’outcomes Physicians’role Transplant cardiology Veno-arterial Veno-venous
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Discussion on Artistry and Techniques of Role Shaping in Drama Performance
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作者 Ruixuan Liang 《Journal of Contemporary Educational Research》 2025年第5期326-331,共6页
Role shaping in dramatic performance is a fusion of art and skills,which involves the deep digging of character,the delicate expression of emotion,and the logical construction of behavior.Actors not only analyze the s... Role shaping in dramatic performance is a fusion of art and skills,which involves the deep digging of character,the delicate expression of emotion,and the logical construction of behavior.Actors not only analyze the script and understand the emotions of the role to create a multi-dimensional,three-dimensional character image,but also need to use the skills of sound,form,lines,and so on,to convey the role’s internal emotions and psychological changes.This process tests the artistic accomplishment and skill level of the actors,and requires them to have keen observation and rich imagination and creativity.Through the analysis of the role of Yu Ji in the Peking Opera Farewell My Concubine,it shows the deep integration of artistry and skill,highlighting the unique charm of dramatic performance. 展开更多
关键词 role shaping Emotion expression Dramatic skill
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Trends in Division of Labor Adjustment in the Asia-Pacific Region Under the Impact of Trump 2.0 and China’s Role in It
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作者 Liu Hongzhong 《Contemporary World》 2025年第3期35-40,共6页
The Asia-Pacific region is the most dynamic part of the global economy.After over 50 years of continuously expanding trade,investment and industrial cooperation,the region has formed a highly-tied multi-level labor di... The Asia-Pacific region is the most dynamic part of the global economy.After over 50 years of continuously expanding trade,investment and industrial cooperation,the region has formed a highly-tied multi-level labor division system covering vertical integration and horizontal complementarity of industrial chains.From the V-shaped development model in the twentieth century to the East Asian production network in the twenty-first century,the intra-industry and intra-product division of labor in the Asia-Pacific region has been ever deepening.However,due to the region’s high dependence on the U.S.market,the division of labor model in the Asia-Pacific suffers structural problems and is relatively fragile.Under the shock of Trump 1.0,countries in the Asia-Pacific region were forced to make adaptive adjustments,causing short-term turmoil in the regional economic order.Trump’s strong return in 2025,driven by the“America First”principle,brought forth a series of policies with strong unilateralism,isolationism and protectionism tendencies within just a few months。 展开更多
关键词 vertical integration horizontal complementarity Chinas role economic order east asian production network Trump trade policies Asia Pacific region division labor
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Parental cognitive ability effects on children’s logical reasoning ability:The mediating role of academic expectation and the family environment
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作者 Qing Wang Haiyan Xu Xuhuan Wang 《Journal of Psychology in Africa》 2025年第4期497-503,共7页
This study investigated the relationship between parental cognitive ability and child logical reasoning ability,and the role of academic expectation and family environment in that relationship.Based on the 2020 China ... This study investigated the relationship between parental cognitive ability and child logical reasoning ability,and the role of academic expectation and family environment in that relationship.Based on the 2020 China Family Panel Studies(CFPS)data,1491 children(girls ratio=53.78%;average grade=6.023 years,school grade standard deviation=1.825 years).Results following multiple regression model(OLS)show that the higher the parental cognitive ability,the higher the children’s logical reasoning ability.Secondly,parental academic expectation serves as a mediator between their cognitive ability and children’s logical reasoning ability for higher logical reasoning by children.Third,a possible family environment acts as a mediator in the relationship between parents’cognitive ability and children’s logical reasoning ability to be higher.We conclude from thesefindings that parents with high cognitive abilities can enhance their children’s logical reasoning skills not only by setting higher academic expectations,but also by cultivating a supportive family environment.Thesefindings imply a need for intervention to improve family quality of life to enhance children’s thinking abilities to optimize their academic learning. 展开更多
关键词 parental cognitive ability children’s logical reasoning ability academic expectation family environment intermediary role
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From Knowledge Authority to Wisdom Collaborator: The Transformation and Reconstruction of the Role of English Teachers in the Era of Gene AI
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作者 JIA Jun 《Journal of Literature and Art Studies》 2025年第3期207-215,共9页
Grounded in educational ecology and constructivist theory,this study examines the challenges and opportunities faced by English teachers in the Gene AI era.While Gene AI is efficient in surface-level tasks,it has limi... Grounded in educational ecology and constructivist theory,this study examines the challenges and opportunities faced by English teachers in the Gene AI era.While Gene AI is efficient in surface-level tasks,it has limitations in cultural interpretation,ethical guidance,and metacognitive development.The paper proposes a tripartite framework for role transformation:cognitive reframing,pedagogical innovation,and ethical repositioning to help tackle the problem of functional substitution anxiety due to AI’s encroachment on traditional roles.The study concludes that English teachers must evolve into“intelligent curators”who can synergize AI’s technical prowess with human wisdom,prioritizing holistic human development over skill acquisition. 展开更多
关键词 English teacher role transformation Generative artificial intelligence(Gene AI) Human-AI collaboration educational ecosystem reconstruction wisdom collaborator
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Role-play联合翻转课堂教学法对护理实习生新生儿复苏知信行的影响 被引量:3
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作者 丁卉 李眉 +3 位作者 陈静 汪婕 蒋丽军 李霖 《临床医学研究与实践》 2024年第26期195-198,共4页
目的分析角色扮演(Role-play)联合翻转课堂教学法对护理实习生新生儿复苏知信行的影响。方法选取2022年10月1日至2023年8月1日在我院产科及儿科实习的80名本科段护理实习生进行前瞻性研究,将其随机分为试验组(采用Role-play联合翻转课... 目的分析角色扮演(Role-play)联合翻转课堂教学法对护理实习生新生儿复苏知信行的影响。方法选取2022年10月1日至2023年8月1日在我院产科及儿科实习的80名本科段护理实习生进行前瞻性研究,将其随机分为试验组(采用Role-play联合翻转课堂教学法进行新生儿复苏技能培训)和对照组(采用传统临床教学法进行新生儿复苏技能培训),各40名。比较两组的教学效果。结果试验组的理论知识、态度信念得分高于对照组,差异具有统计学意义(P<0.05)。试验组的复苏操作得分高于对照组,差异具有统计学意义(P<0.05)。试验组的灵活应变能力、资源利用能力及沟通协作能力得分均高于对照组,差异具有统计学意义(P<0.05)。试验组的教学满意度高于对照组,差异具有统计学意义(P<0.05)。结论Role-play联合翻转课堂教学法在护理实习生新生儿复苏教学中的效果优于传统临床教学法。 展开更多
关键词 role-play教学法 翻转课堂 护理实习生 新生儿复苏 知信行
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Role Dynamic Allocation of Human-Robot Cooperation Based on Reinforcement Learning in an Installation of Curtain Wall
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作者 Zhiguang Liu Shilin Wang +2 位作者 Jian Zhao Jianhong Hao Fei Yu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第1期473-487,共15页
A real-time adaptive roles allocation method based on reinforcement learning is proposed to improve humanrobot cooperation performance for a curtain wall installation task.This method breaks the traditional idea that ... A real-time adaptive roles allocation method based on reinforcement learning is proposed to improve humanrobot cooperation performance for a curtain wall installation task.This method breaks the traditional idea that the robot is regarded as the follower or only adjusts the leader and the follower in cooperation.In this paper,a self-learning method is proposed which can dynamically adapt and continuously adjust the initiative weight of the robot according to the change of the task.Firstly,the physical human-robot cooperation model,including the role factor is built.Then,a reinforcement learningmodel that can adjust the role factor in real time is established,and a reward and actionmodel is designed.The role factor can be adjusted continuously according to the comprehensive performance of the human-robot interaction force and the robot’s Jerk during the repeated installation.Finally,the roles adjustment rule established above continuously improves the comprehensive performance.Experiments of the dynamic roles allocation and the effect of the performance weighting coefficient on the result have been verified.The results show that the proposed method can realize the role adaptation and achieve the dual optimization goal of reducing the sum of the cooperator force and the robot’s Jerk. 展开更多
关键词 Human-robot cooperation roles allocation reinforcement learning
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Understanding the roles of Brønsted/Lewis acid sites on manganese oxide-zeolite hybrid catalysts for low-temperature NH_(3)-SCR
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作者 Hyun Sub Kim Hwangho Lee +2 位作者 Hongbeom Park Inhak Song Do Heui Kim 《Chinese Journal of Catalysis》 SCIE CAS CSCD 2024年第10期79-88,共10页
Although metal oxide-zeolite hybrid materials have long been known to achieve enhanced catalytic activity and selectivity in NO_(x)removal reactions through the inter-particle diffusion of intermediate species,their s... Although metal oxide-zeolite hybrid materials have long been known to achieve enhanced catalytic activity and selectivity in NO_(x)removal reactions through the inter-particle diffusion of intermediate species,their subsequent reaction mechanism on acid sites is still unclear and requires investigation.In this study,the distribution of Brønsted/Lewis acid sites in the hybrid materials was precisely adjusted by introducing potassium ions,which not only selectively bind to Brønsted acid sites but also potentially affect the formation and diffusion of activated NO species.Systematic in situ diffuse reflectance infrared Fourier transform spectroscopy analyses coupled with selective catalytic reduction of NO_(x)with NH_(3)(NH_(3)-SCR)reaction demonstrate that the Lewis acid sites over MnO_(x)are more active for NO reduction but have lower selectivity to N_(2)than Brønsted acids sites.Brønsted acid sites primarily produce N_(2),whereas Lewis acid sites primarily produce N_(2)O,contributing to unfavorable N_(2)selectivity.The Brønsted acid sites present in Y zeolite,which are stronger than those on MnO_(x),accelerate the NH_(3)-SCR reaction in which the nitrite/nitrate species diffused from the MnO_(x)particles rapidly convert into the N_(2).Therefore,it is important to design the catalyst so that the activated NO species formed in MnO_(x)diffuse to and are selectively decomposed on the Brønsted acid sites of H-Y zeolite rather than that of MnO_(x)particle.For the physically mixed H-MnO_(x)+H-Y sample,the abundant Brønsted/Lewis acid sites in H-MnO_(x)give rise to significant consumption of activated NO species before their inter-particle diffusion,thereby hindering the enhancement of the synergistic effects.Furthermore,we found that the intercalated K+in K-MnO_(x)has an unexpected favorable role in the NO reduction rate,probably owing to faster diffusion of the activated NO species on K-MnO_(x)than H-MnO_(x).This study will help to design promising metal oxide-zeolite hybrid catalysts by identifying the role of the acid sites in two different constituents. 展开更多
关键词 Hybrid metal oxide-zeolite The role of acid sites Manganese oxides Physical mixing Selective catalytic reduction of NO_(x)with NH_(3)
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Interaction mechanism between luteoloside and corn silk glycans and the synergistic role in hypoglycemic activity
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作者 Shihui Qin Yanlang Li +6 位作者 Huiyan Shao Yang Yu Yina Yang Yi Zeng Jia Huang Jiang-miao Hu Liu Yang 《Natural Products and Bioprospecting》 CSCD 2024年第1期147-158,共12页
As the two most principal active substances in the corn silk,polysaccharides and flavonoids,the mechanism of interaction between them has been a topic of intense research.This study provides an in-depth investigation ... As the two most principal active substances in the corn silk,polysaccharides and flavonoids,the mechanism of interaction between them has been a topic of intense research.This study provides an in-depth investigation of the interaction mechanism between corn silk glycans and luteoloside(LUT)and the synergistic role that result from this interaction.The interaction mechanism was evaluated by isothermal titration calorimetry(ITC)and circular dichroism(CD),and the synergistic role was evaluated by the expression of glucose transporters(GLUT-1),insulin secretion and surface plasmon resonance(SPR).CD and ITC results indicated that the interaction between CSGs and LUT mainly driven by the Cotton effects,enthalpy and entropy-driven.This interaction precipitated the formation of complexes(CSGs/LUT complexes)between corn silk glycans(CSGs)with four different molecular weights and luteoloside(LUT).Furthermore,the CSGs and LUT play a synergistic role in glucose regulation through GLUT-1 expression and insulin secretion experiments,compared to single luteoloside group. 展开更多
关键词 Corn silk glycans CSGs/LUT complexes The molecular interaction mechanism The synergistic role
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