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The Impact and Response of Automatic Driving Technology Standards on the Determination of Criminal Responsibility for Traffic Accidents in China
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作者 Sun Jianfeng 《科技与法律(中英文)》 2026年第1期134-148,共15页
With the continuous progress of automatic driving technology,automatic driving technology standards are gradually affecting the determination of criminal responsibility for traffic accidents in China.At present,the ch... With the continuous progress of automatic driving technology,automatic driving technology standards are gradually affecting the determination of criminal responsibility for traffic accidents in China.At present,the characteristics and tendency of China's automatic driving technology standards present the situation of high policy relevance coexisting with low normative binding,professionalism coexist with barriers,forefront coexist with ambiguity.Therefore,challenges are presented both theoretically and practically on the determination of criminal responsibility based on automatic driving technology standard..In this regard,the misunderstanding should be clarified in theory:The legal order under the automatic driving technology standard has constitutionality and systematic,and there is a balance between the frontier of automatic driving technology development and the lagging of criminal law.The automatic driving technology risk level system should be built to clarify the boundary of the effectiveness of criminal law norms,seeking fora breakthrough in the application of the establishment of a comprehensive judgment system of the risks and accidents and the system of evidence to prove the system,which clarifies the determination of criminal responsibility under the automatic driving technology standard.This essay hopes to pursue breakthroughs in the application-to establish a comprehensive judgment system of risks and accidents as well as an evidence proof system,so as to clarify the determination of criminal responsibility under automatic driving technology standards. 展开更多
关键词 automatic driving traffic accidents criminal responsibility legal order
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The 2025 version of CSC9000T has been released,using the power of responsibility to chart a new blueprint for high-quality industrial development
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作者 Qiu Shuchen 《China Textile》 2025年第6期19-20,共2页
On November 28th,the launch conference and industry exchange seminar on the"CSC9000T Social Responsibility Management System for Textile and Apparel Enterprises(2025 Edition)"was grandly held in Beijing.Du Y... On November 28th,the launch conference and industry exchange seminar on the"CSC9000T Social Responsibility Management System for Textile and Apparel Enterprises(2025 Edition)"was grandly held in Beijing.Du Yuzhou,former President of the China National Textile and Apparel Council,and Chen Shujin,former Vice President,as well as Sun Ruizhe,Secretary of the Party Committee and President of the China National Textile and Apparel Council,and Vice President Yan Yan,witnessed the release of"CSC900OT 2025". 展开更多
关键词 industry exchange seminar high quality industrial development social responsibility launch conference social responsibility management system textile apparel enterprises CSC T
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Corporate Social Responsibility
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《China Oil & Gas》 2025年第6期46-53,共8页
CNPC Abu Dhabi actively fulfills its overseas social responsibilities,continuously deepens local integration and cultural exchanges,and promotes people-to-people ties between China and foreign countries.It continuousl... CNPC Abu Dhabi actively fulfills its overseas social responsibilities,continuously deepens local integration and cultural exchanges,and promotes people-to-people ties between China and foreign countries.It continuously explores and practices educational cooperation,cultural dissemination,and international exchanges and is committed to building diverse interactive platforms that promote cross-cultural understanding and friendly cooperation.Through long-term commitment to public welfare and active participation in local community development,the company has effectively enhanced its international image and influence,demonstrating CNPC’s character as a central state-owned enterprise that embraces openness,inclusiveness,and win-win cooperation. 展开更多
关键词 overseas social responsibilities cultural exchanges building diverse interactive platforms corporate social responsibility CNPC Abu Dhabi people people ties educational cooperation
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A pathway to local legitimacy:the impact of corporate governance on corporate social responsibility in chaebol‑affiliated firms
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作者 Chune Young Chung Hoje Jo Junyoup Lee 《Financial Innovation》 2025年第1期3286-3323,共38页
Drawing on local legitimacy theory,which posits that firms seek acceptance and approval from their local community and stakeholders,we examine the effect of corporate governance(CG)quality on corporate social responsi... Drawing on local legitimacy theory,which posits that firms seek acceptance and approval from their local community and stakeholders,we examine the effect of corporate governance(CG)quality on corporate social responsibility(CSR)activities in Korea.Enhancing CG quality and engaging in CSR activities are increasingly important for firms’long-term sustainability.Using the KEJI-CSR index and the KCGS CG score,we find that CG quality positively influences CSR activities.Specifically,if the CG quality score increases by one standard deviation,CSR improves by approximately 1.6–2.3%of the mean CSR score.Furthermore,the relationship between CG and CSR is stronger for business conglomerates(chaebol-affiliated firms),suggesting that sound CG practices can promote CSR activities more effectively when the interests of management and stakeholders are better aligned.This finding supports local legitimacy theory.Our findings are robust under various tests,including difference-in-differences analysis and propensity score matching.An interesting policy implication is that multinational enterprises or foreign investors should prioritize the CG quality of their local subsidiaries or investee firms.Better CG practices can enhance CSR activities,which are essential for long-term survival in local markets.This study,however,is limited to Korea and may not be generalizable to other emerging markets with different governance structures. 展开更多
关键词 Corporate social responsibility Corporate governance Local legitimacy theory CHAEBOL Electronic voting system DIFFERENCE-IN-DIFFERENCES
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WHEN HISTORY HERALDS PEACE The victory over fascism stands as both a triumph of justice and a lasting reminder of the responsibility to safeguard peace
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作者 Yan Wei 《China Report ASEAN》 2025年第10期48-49,共2页
In a recent interview with Beijing Review,Wang Chaoguang,former director of the Institute of World History,Chinese Academy of Social Sciences,explained why victory over fascism should be commemorated eight!decades on.... In a recent interview with Beijing Review,Wang Chaoguang,former director of the Institute of World History,Chinese Academy of Social Sciences,explained why victory over fascism should be commemorated eight!decades on.Edited excerpts from the interview follow:Why do Chinese sources often refer to World War II(WWII)as the World Anti-Fascist War?How are they di!erent and what is the relationship between the two? 展开更多
关键词 World History COMMEMORATION victory fascism Anti Fascist War Chinese Sources responsibility Peace World War II
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Environmental Awareness,Satisfaction,and Protection Intentions in Vietnam:The Role of Social Responsibility
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作者 Le Thi Cam Tu Le Thi Gai +2 位作者 Dinh Ngoc Truong Nguyen Thi Hien Nguyen Van Toan 《Journal of Environmental & Earth Sciences》 2025年第8期349-362,共14页
This study examines the relationship between ecological awareness,satisfaction,and the intention to participate in environmental protection in Vietnam,focusing on the mediating role of satisfaction and the moderating ... This study examines the relationship between ecological awareness,satisfaction,and the intention to participate in environmental protection in Vietnam,focusing on the mediating role of satisfaction and the moderating effects of social responsibility and ecological knowledge.While ecological awareness is a key driver of pro-environmental behavior,prior research shows that awareness alone does not always translate into concrete actions.To address this issue,we explore how satisfaction with environmental conditions strengthens the awareness-intention link and how personal responsibility and knowledge further enhance this process.Survey data were collected from 4,615 participants across six provinces,representing diverse ecological and socio-economic contexts.Structural equation modeling(SEM)results indicate that ecological awareness positively influences pro-environmental intention,but this effect is significantly stronger when individuals report higher levels of satisfaction.Satisfaction serves as a central mediator,showing that awareness must be complemented by confidence and trust in environmental outcomes to stimulate behavioral commitment.In addition,social responsibility and ecological knowledge moderate these relationships:individuals with greater responsibility and knowledge demonstrate stronger connections between awareness,satisfaction,and intention.The findings contribute to environmental psychology by emphasizing the interaction of cognitive,affective,and normative factors in shaping ecological behavior.For policymakers,the results highlight the need to design interventions that go beyond awareness-raising.Building satisfaction with environmental policies,fostering a sense of responsibility,and strengthening ecological knowledge are crucial for promoting sustainable behaviors and encouraging active citizen participation in environmental protection in Vietnam. 展开更多
关键词 VIETNAM Ecological Environment Ecological Environmental Protection SATISFACTION Social responsibility
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Making money move: an analysis of corporate social responsibility activities in money transfer firms
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作者 Ọláyẹmí M.Ọlábìyí Jasmine Alam 《Financial Innovation》 2025年第1期3163-3180,共18页
Although research has examined the financial sector’s response to COVID-19,the role of the cross-border money transfer industry remains unclear.This study investigates the corporate social responsibility(CSR)actions ... Although research has examined the financial sector’s response to COVID-19,the role of the cross-border money transfer industry remains unclear.This study investigates the corporate social responsibility(CSR)actions of 22 cross-border money transfer firms headquartered in Canada,the US,and the UK to determine how they supported stakeholders during the pandemic.Using qualitative data analysis software,we analyze textual data from company websites,press releases,and blogs to assess CSR activities.Our findings show that nine of the 22 cross-border money transfer firms engaged in COVID-related CSR efforts and communicated these actions through their controlled channels.Two out of every three firms that publicized their CSR initiatives during the pandemic were not traded in any stock exchange market.This research has two key implications.First,disclosing CSR initiatives through controlled or uncontrolled channels increases the likelihood of attracting socially conscious customers and investors,which could ultimately lead to higher economic profits.Second,economic profit can create a bandwagon effect,encouraging other money transfer firms to integrate CSR activities into their business models,which may enhance the well-being of the communities they serve and rely upon. 展开更多
关键词 Corporate social responsibility COVID-19 Remittances MAXQDA
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VAT Neutrality and Corporate Social Responsibility:Evidence from China’s 2018 VAT Credit Refund Reform
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作者 Ningning Zhang Xiaoyan Guan 《Proceedings of Business and Economic Studies》 2025年第6期127-134,共8页
Taking China’s 2018 value-added tax(VAT)credit refund reform as an exogenous shock to improve VAT neutrality,we use a difference-in-differences approach to explore how the reform affected corporate social responsibil... Taking China’s 2018 value-added tax(VAT)credit refund reform as an exogenous shock to improve VAT neutrality,we use a difference-in-differences approach to explore how the reform affected corporate social responsibility(CSR).We find that the reform motivated firms to improve CSR performance.The reform has a“resource”effect,increasing internal funds and reducing financing costs,thereby enhancing firms’ability to undertake CSR.The reform also has a“reputation”effect,stimulating firms’willingness to engage in CSR to improve their reputations.CSR following the reform increases firm values and reduces bankruptcy risk.Our study provides fresh insights into VAT neutrality theory and is a reference for tax reform in emerging economies. 展开更多
关键词 Corporate social responsibility Reputation effect Resource effect VAT credit refund reform VAT neutrality
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From“Cost Sharing”to“Responsibility Sharing”:Uncertain Prospect of US-Europe Relations
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作者 Song Fang 《Contemporary International Relations》 2025年第2期37-59,共23页
Burden sharing has been a perennial issue in the transatlantic alliance,primarily entailing cost sharing and responsibility sharing.During the first Trump administration,the dispute over cost sharing had been prominen... Burden sharing has been a perennial issue in the transatlantic alliance,primarily entailing cost sharing and responsibility sharing.During the first Trump administration,the dispute over cost sharing had been prominent,while the Biden administration placed more emphasis on responsibility sharing to facilitate its strategic goal of“outcompeting”China.The Ukraine crisis had prompted a US-Europe consensus on cost sharing,but the urgency of responsibility sharing subsequently increased.The shift from jointly providing the economic resources to extensively sharing the security responsibilities ref lects the recalibration of the US strategic focus and its higher expectations for the role of European allies.Nevertheless,Europe's response to the US call for responsibility sharing has been relatively limited.The responsibility sharing within the US-Europe alliance and their future relationship will be subject to the strategic coordination between the two sides and multiple complex factors. 展开更多
关键词 China-US competition cost sharing responsibility sharing US-Europe alliance
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Environmental Target Responsibility System,Governance,and Economic Growth
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作者 Yan Chengliang Zhao Fuyang Niu Huan 《China Economist》 2025年第2期2-27,共26页
This paper develops an economic growth model incorporating China’s Environmental Target Responsibility System(ETRS)to analyze its impact on both economic growth and social welfare.We find that the ETRS’s effect on e... This paper develops an economic growth model incorporating China’s Environmental Target Responsibility System(ETRS)to analyze its impact on both economic growth and social welfare.We find that the ETRS’s effect on economic growth is complex,resulting from the interplay of three key factors:its potential to improve environmental quality,its potential dampening effect on total factor productivity(TFP),and its influence on local government spending on environmental governance.A balanced ETRS can improve environmental quality,promote technological innovation,and enhance social welfare.However,excessively stringent targets and overly emphasized responsibility may lead to declines in both economic growth and social welfare.From the perspective of balancing economic growth and social welfare,we find that the ETRS that maximizes economic growth is less stringent than the ETRS that maximizes social welfare.Crucially,the economic growth cost of shifting from a growth-maximizing to a welfare-maximizing ETRS is minimal.In other words,significant improvements in environmental quality and public well-being can be achieved without substantially sacrificing economic dynamism.This paper attempts to model China’s unique environmental target assessment system within the framework of endogenous growth theory,offering a new perspective for understanding the dynamic relationship between economic growth and environmental quality in China. 展开更多
关键词 Environmental target responsibility system(ETRS) environmental governance economic growth social welfare local government
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Summary of Responsibility-based Teaching in Food Toxicology
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作者 Lili JI Jie CHENG +2 位作者 Zhoulin WU Ting BAI Jiamin ZHANG 《Agricultural Biotechnology》 2025年第5期47-49,52,共4页
Food Toxicology is a core course for the major of food quality and safety.The teaching objective is to enable students to acquire the basic theoretical concepts of food toxicology,understand the toxicity and poisoning... Food Toxicology is a core course for the major of food quality and safety.The teaching objective is to enable students to acquire the basic theoretical concepts of food toxicology,understand the toxicity and poisoning mechanisms of exogenous chemicals in food,and thereby achieve the goal of ensuring food safety.This article summarized the teaching process of the course,aiming to enhance students awareness of food safety.Through the course teaching process,in-class experiments,and small topic presentation sessions,it establishes students sense of responsibility from input to output in an all-round manner,in order to provide an objective basis for improving the teaching of this course. 展开更多
关键词 Food Toxicology TEACHING responsibility
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Research on the Evaluation Index System of Social Responsibility of Small and Medium-Sized Enterprises
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作者 Yang Yang Ali Khatibi Jacquline Tham 《Proceedings of Business and Economic Studies》 2025年第3期1-9,共9页
The social responsibility of small and medium-sized enterprises(SMEs)is very important for themselves and the whole society.The concept and connotation of social responsibility of SMEs have been defined and explained.... The social responsibility of small and medium-sized enterprises(SMEs)is very important for themselves and the whole society.The concept and connotation of social responsibility of SMEs have been defined and explained.The research dimensions of previous scholars on corporate social responsibility(CSR)have been reviewed,and an evaluation index system for social responsibility of SMEs has been constructed based on their characteristics,including four key indicators:community,customers,employees,and environment. 展开更多
关键词 Corporate social responsibility SMES EVALUATION
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Examining the Relationship Between Corporate Social Responsibility Performance and Stock Price Crash Risk
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作者 Dan Zhang Xinran Zeng 《Proceedings of Business and Economic Studies》 2025年第1期44-49,共6页
This paper selects the Corporate Social Responsibility(CSR)index from Hexun.com(2010–2020)and the stock price crash index of China’s Shanghai and Shenzhen A-share listed companies from the China Stock Market&Acc... This paper selects the Corporate Social Responsibility(CSR)index from Hexun.com(2010–2020)and the stock price crash index of China’s Shanghai and Shenzhen A-share listed companies from the China Stock Market&Accounting Research Database(CSMAR)for empirical analysis.By examining the impact of CSR performance on stock price crash risk,this study identifies key relationships and further investigates the moderating role of media promotion and communication as an intermediary to explore the transmission mechanisms and influence between the two.The empirical results indicate that CSR performance is significantly negatively correlated with stock price crash risk,suggesting that strong CSR performance can effectively reduce the likelihood of a stock price crash.Furthermore,additional analysis reveals that media plays a moderating role in the relationship between CSR performance and stock price crash risk.This study aims to contribute to the understanding of the formation mechanisms and analytical paradigms of factors influencing stock price crash risk while providing theoretical support and reference value for risk prevention strategies. 展开更多
关键词 Social responsibility information disclosure Stock price crash risk Information effect
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Research on Optimization of Audit Risk Relationship Model Based on Responsibility Subject
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作者 WANG Shufeng LI Xianglin 《Journal of Modern Accounting and Auditing》 2025年第4期281-286,共6页
Based on the objective reality that audit risk responsibility has mainly been attributed to certified public accountants in the past,and audit standards have not specifically divided the entities responsible for audit... Based on the objective reality that audit risk responsibility has mainly been attributed to certified public accountants in the past,and audit standards have not specifically divided the entities responsible for audit risk responsibility,combined with the understanding of the types of audit risk elements related to audit standards,the differences in the understanding of audit risk and its relationship model application caused by the different audit cultures in China and the West have led to a bias of Chinese certified public accountants to bear inspection risks,which affects their professional enthusiasm and continues to cause accounting firms to be lazy in audit quality management.Based on this,literature research,case analysis,and logical deduction methods were used to redefine the concept of audit risk from the perspective of risk responsibility subjects.The traditional audit risk elements and their relationship models were briefly introduced,and the identification of audit risk elements and optimization of audit risk relationship models were systematically demonstrated. 展开更多
关键词 responsible party audit risk relationship model contract risk report risk
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Institutional Construction of Directors’Climate Legal Responsibility Under the“Dual Carbon”Goals:From the Perspective of Climate Risks
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作者 Wei Qingpo 《Contemporary Social Sciences》 2025年第3期114-135,共22页
Enterprises are the primary entities responsible for the multi-governance of climate risks.Nevertheless,the obligations and duty performance systems for directors,as outlined in the new Company Law of the People’s Re... Enterprises are the primary entities responsible for the multi-governance of climate risks.Nevertheless,the obligations and duty performance systems for directors,as outlined in the new Company Law of the People’s Republic of China(the new Company Law),fall short of adequately addressing the internal demands necessary for effectively managing climate risks.Therefore,it is essential to enhance these systems by incorporating specific duties for directors related to climate issues.The accountability of directors for a company’s liability regarding damages caused by climate change is rooted in the evolving purpose of China’s Company Law,the directors’duty of diligence,and the practical demand for emission reduction.Pursuant to the directors’duties set forth by the Company Law,directors’climate responsibilities mainly include two aspects:diligence and loyalty.Diligence primarily involves the total or partial failure to consider and manage foreseeable significant climate risks.Loyalty pertains to the intentional neglect of significant climate-related risks or to decision-making that does not align with the principle of maximizing the company’s interests.To enforce directors’climate responsibilities,it is necessary to introduce provisions within the Company Law that address directors’duties to control climate risks and establish appropriate compensatory measures.Furthermore,developing evidence standards for directors’liability and overcoming the limitations associated with the objects of directors’fiduciary duties is crucial.In light of the“dual carbon”goals and the foreseeability of significant financial risks posed by climate change,directors are obliged to integrate climate change considerations into corporate strategy,supervision,and disclosure,thereby contributing to the restructure of the regulatory framework governing directors’responsibilities towards green and low-carbon transformation. 展开更多
关键词 “dual carbon ”directors’climate responsibilities duty of diligence duty of loyalty climate change
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茵陈蒿汤对胆汁淤积性肝损伤的干预作用及调控机制 被引量:1
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作者 王琳琳 朱正望 +4 位作者 赵静涵 马瑞雪 王兵 朱平生 苗明三 《中国实验方剂学杂志》 北大核心 2026年第1期71-80,共10页
胆汁淤积性肝损伤是指由各种原因导致的胆汁生成、分泌和排泄障碍诱发胆汁淤积,进而引起肝脏损伤、代谢失调和功能紊乱的肝胆系统疾病,可进一步发展为肝纤维化、肝硬化、肝衰竭甚至导致死亡。目前临床治疗的首选药物为熊去氧胆酸,但存... 胆汁淤积性肝损伤是指由各种原因导致的胆汁生成、分泌和排泄障碍诱发胆汁淤积,进而引起肝脏损伤、代谢失调和功能紊乱的肝胆系统疾病,可进一步发展为肝纤维化、肝硬化、肝衰竭甚至导致死亡。目前临床治疗的首选药物为熊去氧胆酸,但存在不良反应和部分患者不耐受的现实问题。茵陈蒿汤是中医治疗黄疸阳黄证的代表方剂,具有“清热利湿退黄”等功效,在长期临床应用中表现出了良好的疗效,且现代药理学研究发现该方具有抗炎、抗氧化、调节胆汁酸平衡、抑制肝细胞凋亡等保肝作用。对近年茵陈蒿汤治疗胆汁淤积性肝损伤的相关临床及动物实验研究进行整理归纳后发现,茵陈蒿汤可通过调节胆汁酸代谢与排泄、减轻炎症反应、抑制氧化应激、缓解内质网应激(ERS)、抑制肝细胞凋亡、保护肠道黏膜屏障等作用机制干预胆汁淤积性肝损伤的疾病进程。通过对目前研究证实的茵陈蒿汤调控胆汁淤积性肝损伤相关分子机制进行系统阐述,以期为茵陈蒿汤的临床应用和深入研究提供参考。 展开更多
关键词 茵陈蒿汤 胆汁淤积 胆汁酸代谢与排泄 炎症反应 细胞凋亡
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长白仔猪肌肉组织对急性冷刺激的应答反应
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作者 王文涛 汪亮 +3 位作者 杨硕 张童 汪洋洋 张冬杰 《中国畜牧兽医》 北大核心 2026年第3期1250-1260,共11页
【目的】探讨急性冷刺激对长白仔猪生长性能的影响,并解析其肌肉组织能量代谢的调控机制。【方法】选择12头体重相近(13.04 kg±1.63 kg)的雄性长白仔猪,随机分为2组,每组6头。称重后置于动物开放式呼吸测热装置,对照组环境温度设定... 【目的】探讨急性冷刺激对长白仔猪生长性能的影响,并解析其肌肉组织能量代谢的调控机制。【方法】选择12头体重相近(13.04 kg±1.63 kg)的雄性长白仔猪,随机分为2组,每组6头。称重后置于动物开放式呼吸测热装置,对照组环境温度设定为(25±0.3)℃,冷刺激组环境温度设定为(10±0.4)℃,处理60 h后采血、屠宰并测定生长性能,采集的血液用于血清生化指标测定,并取背部肌肉组织样品进行苏木精-伊红(HE)染色和转录组测序,筛选差异表达基因,并对其进行COG注释分类、GO功能和KEGG通路富集分析。随机选取10个差异基因通过实时荧光定量PCR进行验证。【结果】①与对照组相比,冷刺激组长白仔猪出现食欲减退、呆立现象,料重比增高,但差异不显著(P>0.05),平均增重显著降低(P<0.05),血清胰岛素水平极显著降低(P<0.01),肌酸激酶活性显著升高(P<0.05)。②与对照组相比,冷刺激组长白仔猪肌肉组织出现肌纤维排列紊乱,肌束间距增宽等病理损伤。③转录组测序结果显示,与对照组相比,冷刺激组共筛选到705个差异表达基因,其中339个基因显著下调,366个基因显著上调(P<0.05)。④COG注释表明差异基因主要富集于脂质运输和代谢、信号传导等功能;GO分析提示脂代谢和糖代谢过程增强;KEGG通路富集显示维持能量稳态和感知小分子代谢物的AMPK信号通路以及谷胱甘肽代谢通路被显著激活,而免疫防御功能相关通路受到抑制。⑤实时荧光定量PCR验证结果显示,与对照组相比,冷刺激组长白仔猪肌肉中COL3A1、IRS1、ME1、METTL24和NPY1R基因表达显著下调(P<0.05),而DNAH3、SIK1、SLC6A6、SPATA20和TXNRD2基因表达显著上调(P<0.05)。【结论】急性冷刺激可抑制长白仔猪的生长,激活肌肉组织的糖脂代谢通路,并损害免疫防御功能。本研究初步揭示了急性冷刺激下猪肌肉组织的转录调控特征,为抗寒调控机制的深入解析提供理论依据。 展开更多
关键词 长白仔猪 急性冷刺激 肌肉 转录组测序 应答反应
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刺激响应型可注射水凝胶在心肌梗死精准化治疗中的作用与趋势
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作者 刘洋 刘东辉 +3 位作者 徐磊 展旭 孙昊博 康凯 《中国组织工程研究》 北大核心 2026年第8期2072-2080,共9页
背景:心肌梗死病理变化的个体差异性较大,传统的心肌梗死的治疗目前存在个体化及靶向性不足等局限性。刺激响应型可注射水凝胶在心肌梗死的“精准治疗”应用中展示出了巨大潜力。目的:介绍多种刺激响应型可注射水凝胶在心肌梗死中的应... 背景:心肌梗死病理变化的个体差异性较大,传统的心肌梗死的治疗目前存在个体化及靶向性不足等局限性。刺激响应型可注射水凝胶在心肌梗死的“精准治疗”应用中展示出了巨大潜力。目的:介绍多种刺激响应型可注射水凝胶在心肌梗死中的应用进展,重点介绍材料设计及心肌梗死修复效果。方法:检索中国知网、PubMed数据库中刺激响应型可注射水凝胶在心肌梗死治疗中应用的相关文献,中文检索词为“心肌梗死,可注射水凝胶,刺激响应型可注射水凝胶,纳米技术,组织工程”,英文检索词为“Myocardial infarction,injectable hydrogel,stimuli-responsive injectable hydrogel,nanotechnology,tissue engineering”,文献检索时限为各数据库建库至2025年1月,最终选取符合标准的69篇文献进行综述。结果与结论:①心肌梗死病理变化存在不同或者同一个体在时间和空间维度方面的差异,尤其在心肌梗死的炎症期,梗死区微环境恶化形成的严重炎症级联反应加剧心肌细胞死亡,故构建可依据局部病理变化按需给药的载药系统进行“精准治疗”是必要的。②心肌梗死的治疗包括控制炎症、减少活性氧生成、保护心肌细胞及避免细胞外基质重构等。③刺激响应型可注射水凝胶可以精准感受梗死区微环境以及外界刺激变化,从而导致自身形态发生应变以及治疗因子的释放,具有为病变区域提供物理支撑、实现药物及治疗因子可控靶向性输送和减少流失、提高药物及治疗因子的吸收利用率等优势。因此,具有多种功能的刺激响应型可注射水凝胶在推动心肌梗死的精准化治疗中具有巨大潜力。 展开更多
关键词 刺激响应 可注射水凝胶 心肌梗死 纳米技术 组织工程 水凝胶
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跟骨骨折术后切口感染的病原菌耐药性及感染因素分析
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作者 姜洪涛 薛鑫鑫 +3 位作者 聂明洋 王佳宁 王丽颖 李小东 《中国病原生物学杂志》 北大核心 2026年第1期13-16,共4页
目的探讨跟骨骨折术后切口感染的病原菌分布、耐药性、炎性反应指标变化及相关原因。方法选取2019年6月~2024年7月于本院行手术治疗的跟骨骨折患者796例作为研究对象,根据术后是否出现切口感染分为感染组(n=56)和非感染组(n=740),观察... 目的探讨跟骨骨折术后切口感染的病原菌分布、耐药性、炎性反应指标变化及相关原因。方法选取2019年6月~2024年7月于本院行手术治疗的跟骨骨折患者796例作为研究对象,根据术后是否出现切口感染分为感染组(n=56)和非感染组(n=740),观察病原菌分布特征和耐药率;采用Logistic回归分析影响跟骨骨折患者术后切口感染的危险因素。结果796例跟骨骨折患者术后经病原菌检出切口感染56例,分离出病原菌共83株,其中革兰阳性菌、革兰阴性菌、真菌分别为34株(40.96%)、46株(55.42%)、4株(4.82%)。药敏结果显示,金黄色葡萄球菌对青霉素耐药率(81.25%)最高,其次为红霉素(68.75%)、左氧氟沙星(56.25%);表皮葡萄球菌对青霉素耐药率(92.86%)最高,其次为红霉素(64.29%)、复方新诺明(50.00%);大肠埃希菌对氨苄西林耐药率(100.00%)最高,其次为头孢唑啉(86.36%);阴沟肠杆菌对头孢唑啉耐药率(100.00%)最高,其次氨苄西林为(93.33%)。感染组的糖尿病史、术后引流管未放置占比和手术时间、IL-2、CRP、PCT水平均高于非感染组(P<0.05)。多因素Logistic回归分析显示,糖尿病史、术后未放置引流管及IL-2、CRP、PCT水平升高是影响跟骨骨折患者术后切口感染的独立危险因素(P<0.05)。结论跟骨骨折术后切口感染以金黄色葡萄球菌、表皮葡萄球菌、大肠埃希菌、阴沟肠杆菌等病原菌多见,并对青霉素、红霉素、复方新诺明、氨苄西林、头孢唑啉等抗菌药物具有较高的耐药性;且糖尿病史、术后未放置引流管及IL-2、CRP、PCT水平升高是影响术后继发切口感染的危险因素,临床应提高警惕。 展开更多
关键词 跟骨骨折 切口感染 病原菌 耐药性 炎性反应
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山药芡实面包的配方优化及其体外GI分析
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作者 魏宗烽 向晨曦 +3 位作者 李杰 陈晖 杨涵硕 邵颖 《粮食与油脂》 北大核心 2026年第3期96-101,148,共7页
以高筋小麦粉、山药粉、芡实粉、白砂糖为主要原料,制作一款山药芡实面包。以感官评分为考察指标,通过单因素试验结合响应面试验优化面包配方工艺,并对产品的体外血糖生成指数(GI)进行分析。结果表明:山药芡实面包最佳配方为以高筋小麦... 以高筋小麦粉、山药粉、芡实粉、白砂糖为主要原料,制作一款山药芡实面包。以感官评分为考察指标,通过单因素试验结合响应面试验优化面包配方工艺,并对产品的体外血糖生成指数(GI)进行分析。结果表明:山药芡实面包最佳配方为以高筋小麦粉质量为基准,山药粉添加量5.5%、芡实粉添加量5.2%、白砂糖添加量18.4%,在此条件下制得的面包感官评分为84.7±0.2,体外GI为78.31±0.05,较未添加山药和芡实的面包下降了10.7%。研究为山药、芡实功能性食品的开发提供了新思路,也为低GI烘焙产品研发奠定了试验基础。 展开更多
关键词 山药 芡实 感官评分 响应面法 血糖生成指数
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